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Select item 107907711.

Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus

Joanne Dai, Elliott D. SoRelle, Emma Heckenberg, Lingyun Song, Jana M. Cable, Gregory E. Crawford, Micah A. Luftig

mBio. 2024 Jan; 15(1): e02444-23. Published online 2023 Dec 7. doi: 10.1128/mbio.02444-23

PMCID:: PMC10790771

Abstract Article PDF–7.7M

Select item 106378012.

BCL2A1 is associated with tumor-associated macrophages and unfavorable prognosis in human gliomas

Lun Gao, Zhang Ye, Shu Peng, Pan Lei, Ping Song, Zhiyang Li, Long Zhou, Qiuwei Hua, Li Cheng, Hangyu Wei, Junhui Liu, Qiang Cai

Aging (Albany NY) 2023 Oct 31; 15(20): 11611–11638. Published online 2023 Oct 25. doi: 10.18632/aging.205149

PMCID:: PMC10637801

Abstract Article PDF–3.9M

Select item 92720573.

Bulk RNA Sequencing With Integrated Single-Cell RNA Sequencing Identifies BCL2A1 as a Potential Diagnostic and Prognostic Biomarker for Sepsis

Jun Li, Mi Zhou, Jia-Qi Feng, Soon-Min Hong, Shao-Ying Yang, Lang-Xian Zhi, Wan-Yi Lin, Cheng Zhu, Yue-Tian Yu, Liang-Jing Lu

Front Public Health. 2022; 10: 937303. Published online 2022 Jun 27. doi: 10.3389/fpubh.2022.937303

PMCID:: PMC9272057

Abstract Article PDF–3.6M

Select item 75441584.

A redox switch regulates the structure and function of anti-apoptotic BFL-1

Kyle J. Korshavn, Thomas E. Wales, Gregory H. Bird, John R. Engen, Loren D. Walensky

Nat Struct Mol Biol. Author manuscript; available in PMC 2021 Jan 13.

Published in final edited form as: Nat Struct Mol Biol. 2020 Sep; 27(9): 781–789. Published online 2020 Jul 13. doi: 10.1038/s41594-020-0458-9

PMCID:: PMC7544158

Abstract Article PDF–2.3M

Select item 72831365.

Snail augments fatty acid oxidation by suppression of mitochondrial ACC2 during cancer progression

Ji Hye Yang, Nam Hee Kim, Jun Seop Yun, Eunae Sandra Cho, Yong Hoon Cha, Sue Bean Cho, Seon-Hyeong Lee, So Young Cha, Soo-Youl Kim, Jiwon Choi, Tin-Tin Manh Nguyen, Sunghyouk Park, Hyun Sil Kim, Jong In Yook

Life Sci Alliance. 2020 Jul; 3(7): e202000683. Published online 2020 Jun 2. doi: 10.26508/lsa.202000683

PMCID:: PMC7283136

Abstract Article PDF–2.6M

Select item 72060786.

Characterization of a novel human BFL-1-specific monoclonal antibody

Lahiru Gangoda, Charis E. Teh, Michael A. Dengler, Sarah A. Best, Clare E. Weeden, Lin Tai, Erinna F. Lee, Walter D. Fairlie, Kate D. Sutherland, Leonard C. Harrison, Daniel H. Gray, Andreas Strasser, Marco J. Herold

Cell Death Differ. 2020 Feb; 27(2): 826–828. Published online 2019 Nov 12. doi: 10.1038/s41418-019-0454-y

PMCID:: PMC7206078

Article PDF–1018K

Select item 67481317.

BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL

Hector Flores-Romero, Olatz Landeta, Begoña Ugarte-Uribe, Katia Cosentino, Miguel García-Porras, Ana J. García-Sáez, Gorka Basañez

Cell Death Differ. 2019 Oct; 26(10): 1880–1894. Published online 2018 Dec 18. doi: 10.1038/s41418-018-0258-5

PMCID:: PMC6748131

Abstract Article PDF–5.9M

Select item 64935008.

BCL2A1 is a Potential Biomarker for Postoperative Seizure Control in Patients with Low‐grade Gliomas

Gan You, Lin Feng, Wei Yan, Wei Zhang, Yong‐Zhi Wang, Shao‐Wu Li, Shou‐Wei Li, Gui‐Lin Li, Yi‐Jun Song, Chun‐Sheng Kang, Yong‐Ping You, Tao Jiang

CNS Neurosci Ther. 2013 Nov; 19(11): 882–888. Published online 2013 Jul 10. doi: 10.1111/cns.12148

PMCID:: PMC6493500

Abstract Article PDF–322K

Select item 59479609.

Crystal Structures of Anti-Apoptotic BFL-1 and its Complex with a Covalent Stapled Peptide Inhibitor

Edward P. Harvey, Hyuk-Soo Seo, Rachel M. Guerra, Gregory H. Bird, Sirano Dhe-Paganon, Loren D. Walensky

Structure. Author manuscript; available in PMC 2019 Jan 2.

Published in final edited form as: Structure. 2018 Jan 2; 26(1): 153–160.e4. Published online 2017 Dec 21. doi: 10.1016/j.str.2017.11.016

PMCID:: PMC5947960

Abstract Article PDF–1.3M

Select item 337999710.

µ-Calpain Conversion of Antiapoptotic Bfl-1 (BCL2A1) into a Prodeath Factor Reveals Two Distinct alpha-Helices Inducing Mitochondria-Mediated Apoptosis

Juan García Valero, Aurélie Cornut-Thibaut, Romain Jugé, Anne-Laure Debaud, Diana Giménez, Germain Gillet, Nathalie Bonnefoy-Bérard, Jesús Salgado, Gilles Salles, Abdel Aouacheria, Jérôme Kucharczak

PLoS One. 2012; 7(6): e38620. Published online 2012 Jun 20. doi: 10.1371/journal.pone.0038620

PMCID:: PMC3379997

Abstract Article PDF–3.9M

Select item 337612511.

Anti-Apoptotic Bfl-1 Is the Major Effector in Activation-Induced Human Mast Cell Survival

Maria Ekoff, Katarina Lyberg, Maryla Krajewska, Monica Arvidsson, Sabina Rak, John C. Reed, Ilkka Harvima, Gunnar Nilsson

PLoS One. 2012; 7(6): e39117. Published online 2012 Jun 15. doi: 10.1371/journal.pone.0039117

PMCID:: PMC3376125

Abstract Article PDF–1.4M

Select item 337555712.

Tax Protein-induced Expression of Antiapoptotic Bfl-1 Protein Contributes to Survival of Human T-cell Leukemia Virus Type 1 (HTLV-1)-infected T-cells

Héloïse Macaire, Aurélien Riquet, Vincent Moncollin, Marie-Claude Biémont-Trescol, Madeleine Duc Dodon, Olivier Hermine, Anne-Laure Debaud, Renaud Mahieux, Jean-Michel Mesnard, Marlène Pierre, Louis Gazzolo, Nathalie Bonnefoy, Hélène Valentin

J Biol Chem. 2012 Jun 15; 287(25): 21357–21370. Published online 2012 May 2. doi: 10.1074/jbc.M112.340992

Correction in:: J Biol Chem. 2012 Oct 5; 287(41): 34495.

PMCID:: PMC3375557

Abstract Article PDF–2.7M

Select item 316627413.

The C-terminal region of Bfl-1 sensitizes non-small cell lung cancer to gemcitabine-induced apoptosis by suppressing NF-κB activity and down-regulating Bfl-1

Min-Kyoung Kim, Yoon-Kyung Jeon, Jong-Kyu Woo, Yun Choi, Dae-Han Choi, Yeul-Hong Kim, Chul-Woo Kim

Mol Cancer. 2011; 10: 98. Published online 2011 Aug 16. doi: 10.1186/1476-4598-10-98

PMCID:: PMC3166274

Abstract Article PDF–1.4M

Select item 305502414.

Bfl-1 gene expression in breast cancer: its relationship with other prognostic factors.

Ho-Sung Yoon, Sung-Hee Hong, Hee-Jun Kang, Byung Kyun Ko, Sei-Hyun Ahn, Joo-Ryung Huh

J Korean Med Sci. 2003 Apr; 18(2): 225–230. doi: 10.3346/jkms.2003.18.2.225

PMCID:: PMC3055024

Summary PDF–101K

Select item 288071915.

Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist

MJ Simmons, G Fan, W-X Zong, K Degenhardt, E White, C Gélinas

Oncogene. Author manuscript; available in PMC 2010 Jun 4.

Published in final edited form as: Oncogene. 2008 Feb 28; 27(10): 1421–1428. Published online 2007 Sep 3. doi: 10.1038/sj.onc.1210771

PMCID:: PMC2880719

Abstract Article PDF–1.2M

Select item 278158116.

C-terminal Residues Regulate Localization and Function of the Antiapoptotic Protein Bfl-1

Gaelle Brien, Anne-Laure Debaud, Xavier Robert, Lisa Oliver, Marie-Claude Trescol-Biemont, Nicolas Cauquil, Olivier Geneste, Nushin Aghajari, Francois M. Vallette, Richard Haser, Nathalie Bonnefoy-Berard

J Biol Chem. 2009 Oct 30; 284(44): 30257–30263. Published online 2009 Sep 15. doi: 10.1074/jbc.M109.040824

PMCID:: PMC2781581

Abstract Article PDF–1.3M

Select item 236038317.

Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia

A Olsson, M Norberg, A ökvist, K Derkow, A Choudhury, G Tobin, F Celsing, A österborg, R Rosenquist, M Jondal, L M Osorio

Br J Cancer. 2007 Sep 11; 97(6): 769–777. Published online 2007 Aug 28. doi: 10.1038/sj.bjc.6603951

PMCID:: PMC2360383

Abstract Article PDF–215K

Select item 219389918.

Identification of a Polymorphic Gene, BCL2A1, Encoding Two Novel Hematopoietic Lineage-specific Minor Histocompatibility Antigens

Yoshiki Akatsuka, Tetsuya Nishida, Eisei Kondo, Mikinori Miyazaki, Hirohumi Taji, Hiroatsu Iida, Kunio Tsujimura, Makoto Yazaki, Tomoki Naoe, Yasuo Morishima, Yoshihisa Kodera, Kiyotaka Kuzushima, Toshitada Takahashi

J Exp Med. 2003 Jun 2; 197(11): 1489–1500. doi: 10.1084/jem.20021925