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Select item 106469271.

Clinical characteristics of a large familial cohort with Medullary thyroid cancer and germline Cys618Arg RET mutation in an Israeli multicenter study

Rachel Chava Rosenblum, Dania Hirsch, Simona Grozinsky-Glasberg, Carlos Benbassat, Uri Yoel, Avraham Ishay, Sagit Zolotov, Gideon Bachar, Ehud Banne, Sigal Levy, Orit Twito

Front Endocrinol (Lausanne) 2023; 14: 1268193. Published online 2023 Oct 30. doi: 10.3389/fendo.2023.1268193

PMCID:: PMC10646927

Article PDF–889K

Select item 103581282.

Extended RET Gene Analysis in Patients with Apparently Sporadic Medullary Thyroid Cancer: Clinical Benefits and Cost

Susan C. Lindsey, Ilda S. Kunii, Fausto Germano-Neto, Misaki Y. Sittoni, Cléber P. Camacho, Flávia O. F. Valente, Ji H. Yang, Priscila S. Signorini, Rosana Delcelo, Janete M. Cerutti, Rui M. B. Maciel, Magnus R. Dias-da-Silva

Horm Cancer. 2012 Aug; 3(4): 181–186. Published online 2012 May 31. doi: 10.1007/s12672-012-0109-7

PMCID:: PMC10358128

Article PDF–402K

Select item 101661683.

RET Fusion-Positive Non-small Cell Lung Cancer: The Evolving Treatment Landscape

Silvia Novello, Raffaele Califano, Niels Reinmuth, Antonella Tamma, Tarun Puri

Oncologist. 2023 May; 28(5): 402–413. Published online 2023 Feb 23. doi: 10.1093/oncolo/oyac264

PMCID:: PMC10166168

Article PDF–1.0M

Select item 101415254.

RET aberrant cancers and RET inhibitor therapies: Current state-of-the-art and future perspectives

Alfredo Addeo, Ernesto Miranda-Morales, Petra den Hollander, Alex Friedlaender, Herman O. Sintim, Jie Wu, Sendurai A. Mani, Vivek Subbiah

Pharmacol Ther. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Pharmacol Ther. 2023 Feb; 242: 108344. Published online 2023 Jan 9. doi: 10.1016/j.pharmthera.2023.108344

PMCID:: PMC10141525

Article PDF–959K

Select item 101191975.

Successful combination of selpercatinib and radioiodine after pretherapeutic dose estimation in RET-altered thyroid carcinoma

Rudolf A. Werner, Cyrus Sayehli, Heribert Hänscheid, Takahiro Higuchi, Sebastian E. Serfling, Martin Fassnacht, Maria-Elisabeth Goebeler, Andreas K. Buck, Matthias Kroiss

Eur J Nucl Med Mol Imaging. 2023; 50(6): 1833–1834. Published online 2022 Dec 16. doi: 10.1007/s00259-022-06061-8

PMCID:: PMC10119197

Article PDF–580K

Select item 100157896.

RET signaling in breast cancer therapeutic resistance and metastasis

Geoffrey Pecar, Simeng Liu, Jagmohan Hooda, Jennifer M. Atkinson, Steffi Oesterreich, Adrian V. Lee

Breast Cancer Res. 2023; 25: 26. Published online 2023 Mar 14. doi: 10.1186/s13058-023-01622-7

PMCID:: PMC10015789

Article PDF–2.8M

Select item 94900357.

Unexpected structures formed by the kinase RET C634R mutant extracellular domain suggest potential oncogenic mechanisms in MEN2A

Yixin Liu, Orquidea De Castro Ribeiro, Outi Haapanen, Gregory B. Craven, Vivek Sharma, Stephen P. Muench, Adrian Goldman

J Biol Chem. 2022 Oct; 298(10): 102380. Published online 2022 Aug 17. doi: 10.1016/j.jbc.2022.102380

PMCID:: PMC9490035

Article PDF–2.9M

Select item 94410628.

RET fusions as primary oncogenic drivers and secondary acquired resistance to EGFR tyrosine kinase inhibitors in patients with non-small-cell lung cancer

Chunyue Wang, Zhenlong Zhang, Yulan Sun, Song Wang, Mengmeng Wu, Qiuxiang Ou, Yang Xu, Zhiming Chen, Yang Shao, Hong Liu, Peifeng Hou

J Transl Med. 2022; 20: 390. Published online 2022 Sep 4. doi: 10.1186/s12967-022-03593-3

PMCID:: PMC9441062

Article PDF–1.6M

Select item 89259609.

Clinical features and signaling effects of RET D631Y variant multiple endocrine neoplasia type 2 (MEN2)

Ji-young Lee, Su Yeon Kim, Kwan Hoon Jo, Eun Yeong Mo, Eun Sook Kim, Hye Soo Kim, Je Ho Han, Sung-dae Moon

Korean J Intern Med. 2022 Mar; 37(2): 398–410. Published online 2021 Dec 15. doi: 10.3904/kjim.2021.311

PMCID:: PMC8925960

Article PDF–1.1M

Select item 883080710.

Distribution of RET proto‐oncogene variants in children with appendicitis

Jurek Schultz, Ines Freibothe, Michael Haase, Patrick Glatte, Gustavo Barreton, Andreas Ziegler, Heike Görgens, Guido Fitze

Mol Genet Genomic Med. 2022 Feb; 10(2): e1864. Published online 2022 Jan 3. doi: 10.1002/mgg3.1864

PMCID:: PMC8830807

Article PDF–570K

Select item 874821711.

Identification of RET fusions in a Chinese multicancer retrospective analysis by next‐generation sequencing

Minke Shi, Weiran Wang, Jinku Zhang, Bobo Li, Dongxiao Lv, Danhua Wang, Sizhen Wang, Dezhi Cheng, Tonghui Ma

Cancer Sci. 2022 Jan; 113(1): 308–318. Published online 2021 Nov 15. doi: 10.1111/cas.15181

PMCID:: PMC8748217

Article PDF–942K

Select item 868354112.

Association between somatic RET mutations and clinical and genetic characteristics in patients with metastatic colorectal cancer

Yuan‐Zhong Yang, Wan‐Ming Hu, Liang‐Ping Xia, Wen‐Zhuo He

Cancer Med. 2021 Dec; 10(24): 8876–8882. Published online 2021 Nov 5. doi: 10.1002/cam4.4400

PMCID:: PMC8683541

Article PDF–425K

Select item 867216013.

Germline RET Leu56Met Variant Is Likely Not Causative of Multiple Endocrine Neoplasia Type 2

Anna Reimer Hansen, Line Borgwardt, Åse Krogh Rasmussen, Christian Godballe, Morten Møller Poulsen, Filipe G. Vieira, Jes Sloth Mathiesen, Maria Rossing

Front Endocrinol (Lausanne) 2021; 12: 764512. Published online 2021 Dec 1. doi: 10.3389/fendo.2021.764512

PMCID:: PMC8672160

Article PDF–255K

Select item 858397114.

Modifier Role of Common RET Variants in Sporadic Medullary Thyroid Carcinoma

Anna Skalniak, Małgorzata Trofimiuk-Müldner, Elwira Przybylik-Mazurek, Alicja Hubalewska-Dydejczyk

Int J Mol Sci. 2021 Nov; 22(21): 11794. Published online 2021 Oct 30. doi: 10.3390/ijms222111794

PMCID:: PMC8583971

Article PDF–803K

Select item 844558815.

RET Protein Expression in Papillary Renal Cell Carcinoma

Richard Flavin, Stephen P Finn, Toni K Choueiri, Helen Ingoldsby, Martina Ring, Ciara Barrett, Miranda Rogers, Paul Smyth, Esther O’Regan, Eoin Gaffney, John J O'Leary, Massimo Loda, Sabina Signoretti, Orla Sheils

Urol Oncol. Author manuscript; available in PMC 2021 Sep 16.

Published in final edited form as: Urol Oncol. 2012 Nov-Dec; 30(6): 900–905. Published online 2011 Mar 10. doi: 10.1016/j.urolonc.2010.08.025

PMCID:: PMC8445588

Article PDF–583K

Select item 835293216.

Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases

Marialuisa Moccia, Donglin Yang, Naga Rajiv Lakkaniga, Brendan Frett, Nicholas McConnell, Lingtian Zhang, Annalisa Brescia, Giorgia Federico, Lingzhi Zhang, Paolo Salerno, Massimo Santoro, Hong-yu Li, Francesca Carlomagno

Sci Rep. 2021; 11: 16103. Published online 2021 Aug 9. doi: 10.1038/s41598-021-95612-4