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Select item 90994201.

BRD2 Compartmentalizes the Accessible Genome

Liangqi Xie, Peng Dong, Yifeng Qi, Tsung-Han S. Hsieh, Brian P. English, SeolKyoung Jung, Xingqi Chen, Margherita De Marzio, Rafael Casellas, Howard Y. Chang, Bin Zhang, Robert Tjian, Zhe Liu

Nat Genet. Author manuscript; available in PMC 2022 May 13.

Published in final edited form as: Nat Genet. 2022 Apr; 54(4): 481–491. Published online 2022 Apr 11. doi: 10.1038/s41588-022-01044-9

PMCID:: PMC9099420

Abstract Article PDF–7.5M

Select item 77232762.

BRD2 regulation of sigma-2 receptor upon cholesterol deprivation

Hongtao Shen, Jing Li, Xiujie Xie, Huan Yang, Mengxue Zhang, Bowen Wang, K Craig Kent, Jorge Plutzky, Lian-Wang Guo

Life Sci Alliance. 2021 Jan; 4(1): e201900540. Published online 2020 Nov 24. doi: 10.26508/lsa.201900540

PMCID:: PMC7723276

Abstract Article PDF–3.7M

Select item 73072653.

BRD2 induces drug resistance through activation of the RasGRP1/Ras/ERK signaling pathway in adult T‐cell lymphoblastic lymphoma

Xiao‐Peng Tian, Jun Cai, Shu‐Yun Ma, Yu Fang, Hui‐Qiang Huang, Tong‐Yu Lin, Hui‐Lan Rao, Mei Li, Zhong‐Jun Xia, Tie‐Bang Kang, Dan Xie, Qing‐Qing Cai

Cancer Commun (Lond) 2020 Jun; 40(6): 245–259. Published online 2020 May 27. doi: 10.1002/cac2.12039

PMCID:: PMC7307265

Abstract Article PDF–6.6M

Select item 59343024.

DNA methylation of the BRD2 promoter is associated with Juvenile Myoclonic Epilepsy in Caucasians

Shilpa Pathak, James Miller, Emily C Morris, William C L Stewart, David A Greenberg

Epilepsia. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Epilepsia. 2018 May; 59(5): 1011–1019. Published online 2018 Apr 2. doi: 10.1111/epi.14058

PMCID:: PMC5934302

Abstract Article PDF–494K

Select item 56350055.

Spatially restricted loading of BRD2 at DNA double-strand breaks protects H4 acetylation domains and promotes DNA repair

Ozge Gursoy-Yuzugullu, Chelsea Carman, Brendan D. Price

Sci Rep. 2017; 7: 12921. Published online 2017 Oct 10. doi: 10.1038/s41598-017-13036-5

PMCID:: PMC5635005

Abstract Article PDF–4.9M

Select item 39366016.

Activation-induced nuclear translocation of RING3

Ning Guo, Douglas V. Faller, Gerald V. Denis

J Cell Sci. Author manuscript; available in PMC 2014 Feb 27.

Published in final edited form as: J Cell Sci. 2000 Sep; 113(0 17): 3085–3091. doi: 10.1242/jcs.113.17.3085

PMCID:: PMC3936601

Abstract Article PDF–3.5M

Select item 38269937.

The C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing

Jarmila Hnilicová, Samira Hozeifi, Eva Stejskalová, Eva Dušková, Ina Poser, Jana Humpolíčková, Martin Hof, David Staněk

Mol Biol Cell. 2013 Nov 15; 24(22): 3557–3568. doi: 10.1091/mbc.E13-06-0303

PMCID:: PMC3826993

Abstract Article PDF–1.2M

Select item 28442088.

Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain

Takashi Umehara, Yoshihiro Nakamura, Moon Kyoo Jang, Kazumi Nakano, Akiko Tanaka, Keiko Ozato, Balasundaram Padmanabhan, Shigeyuki Yokoyama

J Biol Chem. 2010 Mar 5; 285(10): 7610–7618. Published online 2010 Jan 4. doi: 10.1074/jbc.M109.062422

PMCID:: PMC2844208

Abstract Article PDF–2.9M

Select item 28230669.

Identification of Transcription Complexes that Contain the Double Bromodomain Protein Brd2 and Chromatin Remodeling Machines

Gerald V. Denis, Mark E. McComb, Douglas V. Faller, Anupama Sinha, Paul B. Romesser, Catherine E. Costello

J Proteome Res. Author manuscript; available in PMC 2010 Feb 17.

Published in final edited form as: J Proteome Res. 2006 Mar; 5(3): 502. doi: 10.1021/pr050430u

PMCID:: PMC2823066

Abstract Article PDF–841K

Select item 113495410.

Bromodomain analysis of Brd2-dependent transcriptional activation of cyclin A

Anupama Sinha, Douglas V. Faller, Gerald V. Denis

Biochem J. 2005 Apr 1; 387(Pt 1): 257–269. Prepublished online 2004 Nov 17. Published online 2005 Mar 22. doi: 10.1042/BJ20041793

PMCID:: PMC1134954

Abstract Article PDF–480K

Select item 866416011.

PD-L1 is upregulated via BRD2 in head and neck squamous cell carcinoma models of acquired cetuximab resistance

Neil E. Bhola, Christian Njatcha, Lanlin Hu, Eliot D. Lee, Jamie V. Shiah, Mi-Ok Kim, Daniel E. Johnson, Dr. Jennifer R. Grandis

Head Neck. Author manuscript; available in PMC 2021 Dec 10.

Published in final edited form as: Head Neck. 2021 Nov; 43(11): 3364–3373. Published online 2021 Aug 3. doi: 10.1002/hed.26827

PMCID:: PMC8664160

Abstract Article PDF–501K

Select item 706380712.

Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation

Archit Trivedi, Aanchal Mehrotra, Caitlin E. Baum, Brandon Lewis, Tupa Basuroy, Thomas Blomquist, Robert Trumbly, Fabian V. Filipp, Vijayasaradhi Setaluri, Ivana L. de la Serna

Epigenetics Chromatin. 2020; 13: 14. Published online 2020 Mar 10. doi: 10.1186/s13072-020-00333-z

PMCID:: PMC7063807

Abstract Article PDF–2.7M

Select item 549451013.

Brd4‐Brd2 isoform switching coordinates pluripotent exit and Smad2‐dependent lineage specification

Rosalia Fernandez‐Alonso, Lindsay Davidson, Jens Hukelmann, Michael Zengerle, Alan R Prescott, Angus Lamond, Alessio Ciulli, Gopal P Sapkota, Greg M Findlay

EMBO Rep. 2017 Jul; 18(7): 1108–1122. Published online 2017 Jun 6. doi: 10.15252/embr.201643534

PMCID:: PMC5494510

Abstract Article PDF–2.1M

Select item 317867614.

THE BROMODOMAIN-CONTAINING GENE BRD2 IS REGULATED AT TRANSCRIPTION, SPLICING, AND TRANSLATION LEVELS

Enyuan Shang, Qingping Cui, Xiangyuan Wang, Cheryl Beseler, David A. Greenberg, Debra J. Wolgemuth

J Cell Biochem. Author manuscript; available in PMC 2012 Oct 1.

Published in final edited form as: J Cell Biochem. 2011 Oct; 112(10): 2784–2793. doi: 10.1002/jcb.23192

PMCID:: PMC3178676

Abstract Article PDF–1.2M

Select item 282548215.

Eμ-BRD2 transgenic mice develop B-cell lymphoma and leukemia

Rebecca J. Greenwald, Joseph R. Tumang, Anupama Sinha, Nicolas Currier, Robert D. Cardiff, Thomas L. Rothstein, Douglas V. Faller, Gerald V. Denis

Blood. Author manuscript; available in PMC 2010 Feb 20.

Published in final edited form as: Blood. 2004 Feb 15; 103(4): 1475–1484. Published online 2003 Oct 16. doi: 10.1182/blood-2003-06-2116

PMCID:: PMC2825482

Abstract Article PDF–1.4M

Select item 281933316.

Tumor-specific and Proliferation-specific Gene Expression Typifies Murine Transgenic B Cell Lymphomagenesis

Marc E. Lenburg, Anupama Sinha, Douglas V. Faller, Gerald V. Denis

J Biol Chem. Author manuscript; available in PMC 2010 Feb 10.

Published in final edited form as: J Biol Chem. 2007 Feb 16; 282(7): 4803. Published online 2006 Dec 13. doi: 10.1074/jbc.M605870200

PMCID:: PMC2819333

Abstract Article PDF–1.5M

Select item 206586617.

Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails

Hongda Huang, Jiahai Zhang, Weiqun Shen, Xingsheng Wang, Jiawen Wu, Jihui Wu, Yunyu Shi

BMC Struct Biol. 2007; 7: 57. Published online 2007 Sep 12. doi: 10.1186/1472-6807-7-57

PMCID:: PMC2065866

Abstract Article PDF–2.0M

Select item 156390118.

Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Interacts with Bromodomain Protein Brd4 on Host Mitotic Chromosomes

Jianxin You, Viswanathan Srinivasan, Gerald V. Denis, William J. Harrington, Jr., Mary E. Ballestas, Kenneth M. Kaye, Peter M. Howley

J Virol. 2006 Sep; 80(18): 8909–8919. doi: 10.1128/JVI.00502-06

PMCID:: PMC1563901

Abstract Article PDF–636K

Select item 118036619.

BRD2 (RING3) Is a Probable Major Susceptibility Gene for Common Juvenile Myoclonic Epilepsy

Deb K. Pal, Oleg V. Evgrafov, Paula Tabares, Fengli Zhang, Martina Durner, David A. Greenberg

Am J Hum Genet. 2003 Aug; 73(2): 261–270. Published online 2003 Jun 25. doi: 10.1086/377006

PMCID:: PMC1180366

Abstract Article PDF–262K

Select item 923402120.

Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2

Irene P. Chen, James E. Longbotham, Sarah McMahon, Rahul K. Suryawanshi, Mir M. Khalid, Taha Y. Taha, Takako Tabata, Jennifer M. Hayashi, Frank W. Soveg, Jared Carlson-Stevermer, Meghna Gupta, Meng Yao Zhang, Victor L. Lam, Yang Li, Zanlin Yu, Erron W. Titus, Amy Diallo, Jennifer Oki, Kevin Holden, Nevan Krogan, Danica Galonić Fujimori, Melanie Ott

Cell Rep. 2022 Jul 19; 40(3): 111088. Published online 2022 Jun 27. doi: 10.1016/j.celrep.2022.111088