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Select item 76095681.

Disorders caused by genetic defects associated with GH-dependent genes: PAPPA2 defects.

Masanobu Fujimoto, Melissa Andrew, Andrew Dauber

Mol Cell Endocrinol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Mol Cell Endocrinol. 2020 Dec 1; 518: 110967. Published online 2020 Jul 30. doi: 10.1016/j.mce.2020.110967

PMCID:: PMC7609568

Abstract Article PDF–575K

Select item 75397992.

Uteroplacental Ischemia Is Associated with Increased PAPP-A2

Leah M. Lamale-Smith, Diane L. Gumina, Anita W. Kramer, Vaughn A. Browne, Lilian Toledo-Jaldin, Colleen G. Julian, Virginia D. Winn, Lorna G. Moore

Reprod Sci. 2020 Feb; 27(2): 529–536. Published online 2020 Jan 28. doi: 10.1007/s43032-019-00050-3

PMCID:: PMC7539799

Abstract Article PDF–416K

Select item 48483943.

Differential Expression of Human Placental PAPP-A2 over Gestation and in Preeclampsia

Anita W. Kramer, Leah M. Lamale-Smith, Virginia D. Winn

Placenta. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: Placenta. 2016 Jan; 37: 19–25. Published online 2015 Nov 23. doi: 10.1016/j.placenta.2015.11.004

PMCID:: PMC4848394

Abstract Article PDF–1.6M

Select item 41984814.

Pregnancy Associated Plasma Protein-A2: A Novel Biomarker for Down Syndrome

Swapna Munnangi, Susan J. Gross, Rajeevi Mudankamar, Graça Salcedo, Sandra E. Reznik

Placenta. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Placenta. 2014 Nov; 35(11): 900–906. Published online 2014 Aug 12. doi: 10.1016/j.placenta.2014.08.001

PMCID:: PMC4198481

Abstract Article PDF–1.3M

Select item 40167235.

First-Trimester Levels of Pregnancy-Associated Plasma Protein A2 (PAPP-A2) in the Maternal Circulation Are Elevated in Pregnancies That Subsequently Develop Preeclampsia

Erin J. Crosley, Ursula Durland, Ken Seethram, Scott MacRae, Andrée Gruslin, Julian K. Christians

Reprod Sci. 2014 Jun; 21(6): 754–760. doi: 10.1177/1933719113512532

PMCID:: PMC4016723

Abstract Article PDF–220K

Select item 39301376.

A Replication Study for the Association of rs726252 in PAPPA2 with Developmental Dysplasia of the Hip in Chinese Han Population

Dongquan Shi, Wei Sun, Xingquan Xu, Zheng Hao, Jin Dai, Zhihong Xu, Dongyang Chen, Huajian Teng, Qing Jiang

Biomed Res Int. 2014; 2014: 979520. Published online 2014 Feb 3. doi: 10.1155/2014/979520

PMCID:: PMC3930137

Abstract Article PDF–562K

Select item 30969167.

Regulation of pregnancy-associated plasma protein A2 (PAPPA2) in a human placental trophoblast cell line (BeWo)

Pamela K Wagner, Aki Otomo, Julian K Christians

Reprod Biol Endocrinol. 2011; 9: 48. Published online 2011 Apr 15. doi: 10.1186/1477-7827-9-48

PMCID:: PMC3096916

Abstract Article PDF–321K

Select item 77924198.

PAPP‐A2 and Inhibin A as Novel Predictors for Pregnancy Complications in Women With Suspected or Confirmed Preeclampsia

Rugina I. Neuman, Maaike M. Alblas van der Meer, Daan Nieboer, Langeza Saleh, Koen Verdonk, Bhanu Kalra, Ajay Kumar, Kannan Alpadi, Anton H. van den Meiracker, Willy Visser, A. H. Jan Danser

J Am Heart Assoc. 2020 Oct 6; 9(19): e018219. Published online 2020 Sep 29. doi: 10.1161/JAHA.120.018219

PMCID:: PMC7792419

Abstract Article PDF–566K

Select item 72151829.

Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors

Katie A. Lloyd, Bryony N. Parsons, Michael D. Burkitt, Andrew R. Moore, Stamatia Papoutsopoulou, Malcolm Boyce, Carrie A. Duckworth, Klaire Exarchou, Nathan Howes, Lucille Rainbow, Yongxiang Fang, Claus Oxvig, Steven Dodd, Andrea Varro, Neil Hall, D. Mark Pritchard

Cell Mol Gastroenterol Hepatol. 2020; 10(1): 113–132. Published online 2020 Jan 28. doi: 10.1016/j.jcmgh.2020.01.010

PMCID:: PMC7215182

Abstract Article PDF–7.0M

Select item 539359810.

Treatment With Recombinant Human Insulin-Like Growth Factor-1 Improves Growth in Patients With PAPP-A2 Deficiency

María T. Muñoz-Calvo, Vicente Barrios, Jesús Pozo, Julie A. Chowen, Gabriel Á. Martos-Moreno, Federico Hawkins, Andrew Dauber, Horacio M. Domené, Shoshana Yakar, Ron G. Rosenfeld, Luis A. Pérez-Jurado, Claus Oxvig, Jan Frystyk, Jesús Argente

J Clin Endocrinol Metab. 2016 Nov; 101(11): 3879–3883. Published online 2016 Sep 20. doi: 10.1210/jc.2016-2751

PMCID:: PMC5393598

Abstract Article

Select item 481875311.

Mutations in pregnancy‐associated plasma protein A2 cause short stature due to low IGF‐I availability

Andrew Dauber, María T Muñoz‐Calvo, Vicente Barrios, Horacio M Domené, Soren Kloverpris, Clara Serra‐Juhé, Vardhini Desikan, Jesús Pozo, Radhika Muzumdar, Gabriel Á Martos‐Moreno, Federico Hawkins, Héctor G Jasper, Cheryl A Conover, Jan Frystyk, Shoshana Yakar, Vivian Hwa, Julie A Chowen, Claus Oxvig, Ron G Rosenfeld, Luis A Pérez‐Jurado, Jesús Argente

EMBO Mol Med. 2016 Apr; 8(4): 363–374. Published online 2016 Feb 22. doi: 10.15252/emmm.201506106

PMCID:: PMC4818753

Abstract Article PDF–2.0M

Select item 263090512.

Severe Preeclampsia-Related Changes in Gene Expression at the Maternal-Fetal Interface Include Sialic Acid-Binding Immunoglobulin-Like Lectin-6 and Pappalysin-2

Virginia D. Winn, Matthew Gormley, Agnes C. Paquet, Kasper Kjaer-Sorensen, Anita Kramer, Kristen K. Rumer, Ronit Haimov-Kochman, Ru-Fang Yeh, Michael T. Overgaard, Ajit Varki, Claus Oxvig, Susan J. Fisher

Endocrinology. 2009 Jan; 150(1): 452–462. Published online 2008 Sep 25. doi: 10.1210/en.2008-0990

PMCID:: PMC2630905

Abstract Article

Select item 830383913.

Genetic Study of IL6, GDF5 and PAPPA2 in Association with Developmental Dysplasia of the Hip

Stefan Harsanyi, Radoslav Zamborsky, Lubica Krajciova, Milan Kokavec, Lubos Danisovic

Genes (Basel) 2021 Jul; 12(7): 986. Published online 2021 Jun 28. doi: 10.3390/genes12070986

PMCID:: PMC8303839

Abstract Article PDF–241K

Select item 723829414.

Anthropometric and biochemical correlates of PAPP-A2, free IGF-I, and IGFBP-3 in childhood

Masanobu Fujimoto, Jane C Khoury, Philip R Khoury, Bhanu Kalra, Ajay Kumar, Patrick Sluss, Claus Oxvig, Vivian Hwa, Andrew Dauber

Eur J Endocrinol. Author manuscript; available in PMC 2020 May 20.

Published in final edited form as: Eur J Endocrinol. 2020 Mar; 182(3): 363–374. doi: 10.1530/EJE-19-0859

PMCID:: PMC7238294

Abstract Article PDF–942K

Select item 592861415.

Placental expression of PAPPA, PAPPA-2 and PLAC-1 in pregnacies is associated with FGR

Stavros Sifakis, Vasilis P. Androutsopoulos, Artemis Pontikaki, Alexis Velegrakis, George I. Papaioannou, Ourania Koukoura, Demetrios A. Spandidos, Nikos Papantoniou

Mol Med Rep. 2018 May; 17(5): 6435–6440. Published online 2018 Mar 9. doi: 10.3892/mmr.2018.8721

PMCID:: PMC5928614

Abstract Article PDF–742K

Select item 285488716.

A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

Anne B. Newman, Stefan Walter, Kathryn L. Lunetta, Melissa E. Garcia, P. Eline Slagboom, Kaare Christensen, Alice M. Arnold, Thor Aspelund, Yurii S. Aulchenko, Emelia J. Benjamin, Lene Christiansen, Ralph B. D'Agostino, Sr, Annette L. Fitzpatrick, Nora Franceschini, Nicole L. Glazer, Vilmundur Gudnason, Albert Hofman, Robert Kaplan, David Karasik, Margaret Kelly-Hayes, Douglas P. Kiel, Lenore J. Launer, Kristin D. Marciante, Joseph M. Massaro, Iva Miljkovic, Michael A. Nalls, Dena Hernandez, Bruce M. Psaty, Fernando Rivadeneira, Jerome Rotter, Sudha Seshadri, Albert V. Smith, Kent D. Taylor, Henning Tiemeier, Hae-Won Uh, André G. Uitterlinden, James W. Vaupel, Jeremy Walston, Rudi G. J. Westendorp, Tamara B. Harris, Thomas Lumley, Cornelia M. van Duijn, Joanne M. Murabito

J Gerontol A Biol Sci Med Sci. 2010 May; 65A(5): 478–487. doi: 10.1093/gerona/glq028

PMCID:: PMC2854887

Abstract Article PDF–472K

Select item 122206817.

Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin.

H B Boldt, M T Overgaard, L S Laursen, K Weyer, L Sottrup-Jensen, C Oxvig

Biochem J. 2001 Sep 1; 358(Pt 2): 359–367. doi: 10.1042/0264-6021:3580359

PMCID:: PMC1222068

Summary PDF–234K

Select item 433458718.

Fractional exhaled nitric oxide in childhood is associated with 17q11.2-q12 and 17q12-q21 variants

Ralf JP van der Valk, Liesbeth Duijts, Nicolas J Timpson, Muhammad T Salam, Marie Standl, John A Curtin, Jon Genuneit, Marjan Kerhof, Eskil Kreiner-Møller, Alejandro Cáceres, Anna Gref, Liming L Liang, H Rob Taal, Emmanuelle Bouzigon, Florence Demenais, Rachel Nadif, Carole Ober, Emma E Thompson, Karol Estrada, Albert Hofman, André G Uitterlinden, Cornélia van Duijn, Fernando Rivadeneira, Xia Li, Sandrah P Eckel, Kiros Berhane, W James Gauderman, Raquel Granell, David M Evans, Beate St Pourcain, Wendy McArdle, John P Kemp, George Davey Smith, Carla MT Tiesler, Claudia Flexeder, Angela Simpson, Clare S Murray, Oliver Fuchs, Dirkje S Postma, Klaus Bønnelykke, Maties Torrent, Martin Andersson, Patrick Sleiman, Hakon Hakonarson, William O Cookson, Miriam F Moffatt, Lavinia Paternoster, Erik Melén, Jordi Sunyer, Hans Bisgaard, Gerard H Koppelman, Markus Ege, Adnan Custovic, Joachim Heinrich, Frank D Gilliland, Alexander J Henderson, Vincent WV Jaddoe, Johan C de Jongste, the EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium

J Allergy Clin Immunol. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: J Allergy Clin Immunol. 2014 Jul; 134(1): 46–55. Published online 2013 Dec 6. doi: 10.1016/j.jaci.2013.08.053

PMCID:: PMC4334587

Abstract Article PDF–1013K

Select item 360788619.

A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis

Nicolas Greliche, Marine Germain, Jean-Charles Lambert, William Cohen, Marion Bertrand, Anne-Marie Dupuis, Luc Letenneur, Mark Lathrop, Philippe Amouyel, Pierre-Emmanuel Morange, David-Alexandre Trégouët

BMC Med Genet. 2013; 14: 36. Published online 2013 Mar 20. doi: 10.1186/1471-2350-14-36

PMCID:: PMC3607886

Abstract Article PDF–191K

Select item 275281120.

Sequential Use of Transcriptional Profiling, Expression Quantitative Trait Mapping, and Gene Association Implicates MMP20 in Human Kidney Aging

Heather E. Wheeler, E. Jeffrey Metter, Toshiko Tanaka, Devin Absher, John Higgins, Jacob M. Zahn, Julie Wilhelmy, Ronald W. Davis, Andrew Singleton, Richard M. Myers, Luigi Ferrucci, Stuart K. Kim

PLoS Genet. 2009 Oct; 5(10): e1000685. Published online 2009 Oct 16. doi: 10.1371/journal.pgen.1000685

PMCID:: PMC2752811

Abstract Article PDF–409K

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