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Select item 70107001.

Investigation of DNA variants specific to ROBO2 Isoform ‘a’ in Irish vesicoureteric reflux patients reveals marked CpG island variation

John M. Darlow, Mark G. Dobson, Andrew J. Green, Prem Puri, David E. Barton

Sci Rep. 2020; 10: 2265. Published online 2020 Feb 10. doi: 10.1038/s41598-020-58818-6

PMCID:: PMC7010700

Abstract Article PDF–1.1M

Select item 40628142.

Down-regulation of ROBO2 Expression in Prostate Cancers

Youn Jin Choi, Nam Jin Yoo, Sug Hyung Lee

Pathol Oncol Res. 2014; 20(3): 517–519. Published online 2013 Nov 24. doi: 10.1007/s12253-013-9722-1

PMCID:: PMC4062814

Abstract Article PDF–393K

Select item 23909673.

ROBO2 Gene Variants Are Associated with Familial Vesicoureteral Reflux

Aida M. Bertoli-Avella, Maria Luisa Conte, Francesca Punzo, Bianca M. de Graaf, Giuliana Lama, Angela La Manna, Cesare Polito, Carolina Grassia, Bruno Nobili, Pier Francesco Rambaldi, Ben A. Oostra, Silverio Perrotta

J Am Soc Nephrol. 2008 Apr; 19(4): 825–831. doi: 10.1681/ASN.2007060692

PMCID:: PMC2390967

Abstract Article

Select item 110119914.

Overexpression of miR-25 Downregulates the Expression of ROBO2 in Idiopathic Intellectual Disability

Rosa María Ordoñez-Razo, Yessica Gutierrez-López, María Antonieta Araujo-Solis, Gloria Benitez-King, Israel Ramírez-Sánchez, Gabriela Galicia

Int J Mol Sci. 2024 Apr; 25(7): 3953. Published online 2024 Apr 2. doi: 10.3390/ijms25073953

PMCID:: PMC11011991

Abstract Article PDF–3.9M

Select item 91738165.

An ancient founder mutation located between ROBO1 and ROBO2 is responsible for increased microtia risk in Amerindigenous populations

Daniel Quiat, Seong Won Kim, Qi Zhang, Sarah U. Morton, Alexandre C. Pereira, Steven R. DePalma, Jon A. L. Willcox, Barbara McDonough, Daniel M. DeLaughter, Joshua M. Gorham, Justin J. Curran, Melissa Tumblin, Yamileth Nicolau, Maria A. Artunduaga, Lourdes Quintanilla-Dieck, Gabriel Osorno, Luis Serrano, Usama Hamdan, Roland D. Eavey, Christine E. Seidman, J. G. Seidman

Proc Natl Acad Sci U S A. 2022 May 24; 119(21): e2203928119. Published online 2022 May 18. doi: 10.1073/pnas.2203928119

PMCID:: PMC9173816

Abstract Article PDF–2.6M

Select item 67565756.

Roundabout signaling pathway involved in the pathogenesis of COPD by integrative bioinformatics analysis

Yuan-Zhen Lin, Xiao-Ning Zhong, Xin Chen, Yi Liang, Hui Zhang, Dong-Lan Zhu

Int J Chron Obstruct Pulmon Dis. 2019; 14: 2145–2162. Published online 2019 Sep 18. doi: 10.2147/COPD.S216050

PMCID:: PMC6756575

Abstract Article PDF–9.3M

Select item 46747657.

Whole-exome and targeted sequencing identify ROBO1 and ROBO2 mutations as progression-related drivers in myelodysplastic syndromes

Feng Xu, Ling-Yun Wu, Chun-Kang Chang, Qi He, Zheng Zhang, Li Liu, Wen-Hui Shi, Juan Guo, Yang Zhu, You-Shan Zhao, Shu-Cheng Gu, Cheng-Ming Fei, Dong Wu, Li-Yu Zhou, Ji-Ying Su, Lu-Xi Song, Chao Xiao, Xiao Li

Nat Commun. 2015; 6: 8806. Published online 2015 Nov 26. doi: 10.1038/ncomms9806

PMCID:: PMC4674765

Abstract Article PDF–1.8M

Select item 64330478.

Robo2 contains a cryptic binding site for neural EGFL-like (NELL) protein 1/2

Naoka Yamamoto, Manabu Kashiwagi, Manami Ishihara, Takaaki Kojima, Andrés D. Maturana, Shun'ichi Kuroda, Tomoaki Niimi

J Biol Chem. 2019 Mar 22; 294(12): 4693–4703. Published online 2019 Jan 30. doi: 10.1074/jbc.RA118.005819

PMCID:: PMC6433047

Abstract Article PDF–1.6M

Select item 48530369.

Human placental multipotent mesenchymal stromal cells modulate placenta angiogenesis through Slit2-Robo signaling

Cheng-Yi Chen, Chin-Han Tsai, Chia-Yu Chen, Yi-Hsin Wu, Chie-Pein Chen

Cell Adh Migr. 2016 Jan-Apr; 10(1-2): 66–76. Published online 2016 Jan 8. doi: 10.1080/19336918.2015.1108510

PMCID:: PMC4853036

Abstract Article PDF–736K

Select item 337476410.

Inactivation of SLIT2-ROBO1/2 Pathway in Premalignant Lesions of Uterine Cervix: Clinical and Prognostic Significances

Sraboni Mitra, Dipanjana Mazumder-Indra, Ranajit K. Mondal, Partha S. Basu, Anup Roy, Susanta Roychoudhury, Chinmay K. Panda

PLoS One. 2012; 7(6): e38342. Published online 2012 Jun 13. doi: 10.1371/journal.pone.0038342

PMCID:: PMC3374764

Abstract Article PDF–2.3M

Select item 185271411.

Disruption of ROBO2 Is Associated with Urinary Tract Anomalies and Confers Risk of Vesicoureteral Reflux

Weining Lu, Albertien M. van Eerde, Xueping Fan, Fabiola Quintero-Rivera, Shashikant Kulkarni, Heather Ferguson, Hyung-Goo Kim, Yanli Fan, Qiongchao Xi, Qing-gang Li, Damien Sanlaville, William Andrews, Vasi Sundaresan, Weimin Bi, Jiong Yan, Jacques C. Giltay, Cisca Wijmenga, Tom P. V. M. de Jong, Sally A. Feather, Adrian S. Woolf, Yi Rao, James R. Lupski, Michael R. Eccles, Bradley J. Quade, James F. Gusella, Cynthia C. Morton, Richard L. Maas

Am J Hum Genet. 2007 Apr; 80(4): 616–632. Published online 2007 Feb 14. doi: 10.1086/512735

PMCID:: PMC1852714

Abstract Article PDF–1.0M

Select item 417558712.

Common variation near ROBO2 is associated with expressive vocabulary in infancy

Beate St Pourcain, Rolieke A.M. Cents, Andrew J.O. Whitehouse, Claire M.A. Haworth, Oliver S.P. Davis, Paul F. O’Reilly, Susan Roulstone, Yvonne Wren, Qi W. Ang, Fleur P. Velders, David M. Evans, John P. Kemp, Nicole M. Warrington, Laura Miller, Nicholas J. Timpson, Susan M. Ring, Frank C. Verhulst, Albert Hofman, Fernando Rivadeneira, Emma L. Meaburn, Thomas S. Price, Philip S. Dale, Demetris Pillas, Anneli Yliherva, Alina Rodriguez, Jean Golding, Vincent W.V. Jaddoe, Marjo-Riitta Jarvelin, Robert Plomin, Craig E. Pennell, Henning Tiemeier, George Davey Smith

Nat Commun. 2014 Sep 16; 5: 4831. Published online 2014 Sep 16. doi: 10.1038/ncomms5831

PMCID:: PMC4175587

Abstract Article PDF–686K

Select item 279928613.

Whole-Genome Linkage and Association Scan in Primary, Nonsyndromic Vesicoureteric Reflux

Heather J. Cordell, Rebecca Darlay, Pimphen Charoen, Aisling Stewart, Ambrose M. Gullett, Heather J. Lambert, Sue Malcolm, Sally A. Feather, Timothy H.J. Goodship, Adrian S. Woolf, Rajko B. Kenda, Judith A. Goodship, for the UK VUR Study Group

J Am Soc Nephrol. 2010 Jan; 21(1): 113–123. doi: 10.1681/ASN.2009060624

PMCID:: PMC2799286

Abstract Article

Select item 449785714.

Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 Confer Risk for Congenital Anomalies of the Kidney and Urinary Tract

Daw-Yang Hwang, Stefan Kohl, Xueping Fan, Asaf Vivante, Stefanie Chan, Gabriel C Dworschak, Julian Schulz, Albertien M van Eerde, Alina C Hilger, Heon Yung Gee, Tracie Pennimpede, Bernhard G Herrmann, Glenn van de Hoek, Kirsten Y Renkema, Christoph Schell, Tobias B Huber, Heiko M Reutter, Neveen A Soliman, Natasa Stajic, Radovan Bogdanovic, Elijah O Kehinde, Richard P Lifton, Velibor Tasic, Weining Lu, Friedhelm Hildebrandt

Hum Genet. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: Hum Genet. 2015 Aug; 134(8): 905–916. Published online 2015 May 31. doi: 10.1007/s00439-015-1570-5

PMCID:: PMC4497857

Abstract Article PDF–2.5M

Select item 264395315.

A Genome-Wide Association Study of Schizophrenia Using Brain Activation as a Quantitative Phenotype

Steven G. Potkin, Jessica A. Turner, Guia Guffanti, Anita Lakatos, James H. Fallon, Dana D. Nguyen, Daniel Mathalon, Judith Ford, John Lauriello, Fabio Macciardi, FBIRN

Schizophr Bull. 2009 Jan; 35(1): 96–108. Published online 2008 Nov 20. doi: 10.1093/schbul/sbn155

PMCID:: PMC2643953

Abstract Article PDF–1.5M

Select item 336697116.

Genome-Wide Association Study of Circulating Estradiol, Testosterone, and Sex Hormone-Binding Globulin in Postmenopausal Women

Jennifer Prescott, Deborah J. Thompson, Peter Kraft, Stephen J. Chanock, Tina Audley, Judith Brown, Jean Leyland, Elizabeth Folkerd, Deborah Doody, Susan E. Hankinson, David J. Hunter, Kevin B. Jacobs, Mitch Dowsett, David G. Cox, Douglas F. Easton, Immaculata De Vivo

PLoS One. 2012; 7(6): e37815. Published online 2012 Jun 4. doi: 10.1371/journal.pone.0037815

PMCID:: PMC3366971

Abstract Article PDF–138K

Select item 236206717.

A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs)

David Melzer, John R. B. Perry, Dena Hernandez, Anna-Maria Corsi, Kara Stevens, Ian Rafferty, Fulvio Lauretani, Anna Murray, J. Raphael Gibbs, Giuseppe Paolisso, Sajjad Rafiq, Javier Simon-Sanchez, Hana Lango, Sonja Scholz, Michael N. Weedon, Sampath Arepalli, Neil Rice, Nicole Washecka, Alison Hurst, Angela Britton, William Henley, Joyce van de Leemput, Rongling Li, Anne B. Newman, Greg Tranah, Tamara Harris, Vijay Panicker, Colin Dayan, Amanda Bennett, Mark I. McCarthy, Aimo Ruokonen, Marjo-Riitta Jarvelin, Jack Guralnik, Stefania Bandinelli, Timothy M. Frayling, Andrew Singleton, Luigi Ferrucci

PLoS Genet. 2008 May; 4(5): e1000072. Published online 2008 May 9. doi: 10.1371/journal.pgen.1000072

PMCID:: PMC2362067

Abstract Article PDF–442K

Select item 377587418.

Genetic variants associated with disordered eating

Tracey D Wade, Scott Gordon, Sarah Medland, Cynthia M. Bulik, Andrew C Heath, Grant W Montgomery, Nicholas G Martin

Int J Eat Disord. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Int J Eat Disord. 2013 Sep; 46(6): 594–608. Published online 2013 Apr 9. doi: 10.1002/eat.22133

PMCID:: PMC3775874

Abstract Article PDF–2.1M

Select item 304781419.

Proteomic profiling of Myc-associated proteins

Pooja Agrawal, Kebing Yu, Arthur R Salomon, John M Sedivy

Cell Cycle. 2010 Dec 15; 9(24): 4908–4921. Published online 2010 Dec 15. doi: 10.4161/cc.9.24.14199

PMCID:: PMC3047814

Abstract Article PDF–1.6M

Select item 650411920.

Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer‐related pathways in breast cancer

Yan Liu, Jian Li, Zhifang Ma, Jun Zhang, Yuzhi Wang, Zhenghong Yu, Xue Lin, Zhi Xu, Qian Su, Li An, Yehui Zhou, Xinxing Ma, Yiwen Yang, Feifei Wang, Qingfei Chen, Yunchao Zhang, Jilinlin Wang, Huilin Zheng, Aihua Shi, Shuang Yu, Jingzhong Zhang, Weiyong Zhao, Liming Chen

Cancer Med. 2019 Feb; 8(2): 729–741. Published online 2019 Jan 16. doi: 10.1002/cam4.1938

PMCID:: PMC6504119

Abstract Article PDF–1.3M

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PMC Links for Gene (Select 6092) (30)
PMC
Homo sapiens roundabout guidance receptor 2 (ROBO2), transcript variant 11, mRNA
Homo sapiens roundabout guidance receptor 2 (ROBO2), transcript variant 11, mRNA
gi|1804072840|ref|NM_001378195.1|

Nucleotide
PREDICTED: Rattus norvegicus mitogen-activated protein kinase kinase kinase kina...
PREDICTED: Rattus norvegicus mitogen-activated protein kinase kinase kinase kinase 4 (Map4k4), transcript variant X48, mRNA
gi|2678970036|ref|XM_063266928.1|

Nucleotide
PREDICTED: Rattus norvegicus mitogen-activated protein kinase kinase kinase kina...
PREDICTED: Rattus norvegicus mitogen-activated protein kinase kinase kinase kinase 4 (Map4k4), transcript variant X8, mRNA
gi|2678969970|ref|XM_039083228.2|

Nucleotide
PREDICTED: Rattus norvegicus mitogen-activated protein kinase kinase kinase kina...
PREDICTED: Rattus norvegicus mitogen-activated protein kinase kinase kinase kinase 4 (Map4k4), transcript variant X42, mRNA
gi|2678970024|ref|XM_063266922.1|

Nucleotide

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