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Select item 105223831.

Identification of ROCK1 as a novel biomarker for postmenopausal osteoporosis and pan-cancer analysis

Bowen Lai, Heng Jiang, Yuan Gao, Xuhui Zhou

Aging (Albany NY) 2023 Sep 15; 15(17): 8873–8907. Published online 2023 Sep 7. doi: 10.18632/aging.205004

PMCID:: PMC10522383

Abstract Article PDF–6.0M

Select item 82668952.

Impact of plasma 5-hydroxyindoleacetic acid, a serotonin metabolite, on clinical outcome in septic shock, and its effect on vascular permeability

Takeshi Tanaka, Masahiko Mori, Motohiro Sekino, Ushio Higashijima, Masahiro Takaki, Yoshiro Yamashita, Satoshi Kakiuchi, Masato Tashiro, Konosuke Morimoto, Osamu Tasaki, Koichi Izumikawa

Sci Rep. 2021; 11: 14146. Published online 2021 Jul 8. doi: 10.1038/s41598-021-93649-z

PMCID:: PMC8266895

Abstract Article PDF–1010K

Select item 73434643.

ROCK1 knockdown inhibits non-small-cell lung cancer progression by activating the LATS2-JNK signaling pathway

Ting Xin, Wei Lv, Dongmei Liu, Yongle Jing, Fang Hu

Aging (Albany NY) 2020 Jun 30; 12(12): 12160–12174. Published online 2020 Jun 17. doi: 10.18632/aging.103386

PMCID:: PMC7343464

Abstract Article PDF–1.9M

Select item 67819854.

Up regulation of Rho-associated coiled-coil containing kinase1 (ROCK1) is associated with genetic instability and poor prognosis in prostate cancer

Stefan Steurer, Benjamin Hager, Franziska Büscheck, Doris Höflmayer, Maria Christina Tsourlakis, Sarah Minner, Till S. Clauditz, Claudia Hube-Magg, Andreas M. Luebke, Ronald Simon, Jakob R. Izbicki, Eike Burandt, Guido Sauter, Christoph Fraune, Sören Weidemann, Thorsten Schlomm, Hans Heinzer, Alexander Haese, Markus Graefen, Hartwig Huland, Asmus Heumann

Aging (Albany NY) 2019 Sep 30; 11(18): 7859–7879. Published online 2019 Sep 25. doi: 10.18632/aging.102294

PMCID:: PMC6781985

Abstract Article PDF–4.9M

Select item 67442475.

Rho-Associated Coiled-Coil Kinase 1 Translocates to the Nucleus and Inhibits Human Cytomegalovirus Propagation

Erez Eliyahu, Osnat Tirosh, Martina Dobesova, Aharon Nachshon, Michal Schwartz, Noam Stern-Ginossar

J Virol. 2019 Oct 1; 93(19): e00453-19. Prepublished online 2019 Jul 10. Published online 2019 Sep 12. doi: 10.1128/JVI.00453-19

PMCID:: PMC6744247

Abstract Article PDF–1.8M

Select item 67418466.

ROCK1 promotes migration and invasion of non-small-cell lung cancer cells through the PTEN/PI3K/FAK pathway

Changpeng Hu, Huyue Zhou, Yali Liu, Jingbin Huang, Wuyi Liu, Qian Zhang, Qin Tang, Fangfang Sheng, Guobing Li, Rong Zhang

Int J Oncol. 2019 Oct; 55(4): 833–844. Published online 2019 Aug 30. doi: 10.3892/ijo.2019.4864

PMCID:: PMC6741846

Abstract Article PDF–3.1M

Select item 67185357.

Rho‐associated coiled‐coil kinase 1 activation mediates amyloid precursor protein site‐specific Ser655 phosphorylation and triggers amyloid pathology

Yong‐Bo Hu, Ru‐Jing Ren, Yong‐Fang Zhang, Yue Huang, Hai‐Lun Cui, Chao Ma, Wen‐Ying Qiu, Hao Wang, Pei‐Jing Cui, Hong‐Zhuan Chen, Gang Wang

Aging Cell. 2019 Oct; 18(5): e13001. Published online 2019 Jul 9. doi: 10.1111/acel.13001

PMCID:: PMC6718535

Abstract Article PDF–2.3M

Select item 55719858.

Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer

Clifford J. Whatcott, Serina Ng, Michael T. Barrett, Galen Hostetter, Daniel D. Von Hoff, Haiyong Han

PLoS One. 2017; 12(8): e0183871. Published online 2017 Aug 25. doi: 10.1371/journal.pone.0183871

PMCID:: PMC5571985

Abstract Article PDF–6.1M

Select item 55372299.

ROCK1 is a novel Rac1 effector to regulate tubular endocytic membrane formation during clathrin-independent endocytosis

David Soriano-Castell, Albert Chavero, Carles Rentero, Marta Bosch, Maite Vidal-Quadras, Albert Pol, Carlos Enrich, Francesc Tebar

Sci Rep. 2017; 7: 6866. Published online 2017 Jul 31. doi: 10.1038/s41598-017-07130-x

PMCID:: PMC5537229

Abstract Article PDF–11M

Select item 510072610.

Investigation of Rho-Kinase Expressions and Polymorphisms in Mantle Cell Lymphoma Patients

Didar Yanardağ Açık, Mehmet Yılmaz, İbrahim Sarı, Serdar Öztuzcu, Zeynel A. Sayıner, Salih Subari, Abdullah T. Demiryürek

Turk J Haematol. 2016 Jun; 33(2): 141–147. Published online 2016 May 16. doi: 10.4274/tjh.2015.0193

PMCID:: PMC5100726

Abstract Article PDF–267K

Select item 499634711.

Melatonin decreases breast cancer metastasis by modulating Rho-associated kinase protein-1 expression

Thaiz Ferraz Borin, Ali Syed Arbab, Gabriela Bottaro Gelaleti, Lívia Carvalho Ferreira, Marina Gobbe Moschetta, Bruna Victorasso Jardim-Perassi, ASM Iskander, Nadimpalli Ravi S. Varma, Adarsh Shankar, Verena Benedick Coimbra, Vanessa Alves Fabri, Juliana Garcia de Oliveira, Debora Aparecida Pires de Campos Zuccari

J Pineal Res. Author manuscript; available in PMC 2016 Aug 24.

Published in final edited form as: J Pineal Res. 2016 Jan; 60(1): 3–15. Published online 2015 Oct 20. doi: 10.1111/jpi.12270

PMCID:: PMC4996347

Abstract Article PDF–3.8M

Select item 493965612.

Intercellular Adhesion-Dependent Cell Survival and ROCK-Regulated Actomyosin-Driven Forces Mediate Self-Formation of a Retinal Organoid

Albert Lowe, Raven Harris, Punita Bhansali, Ales Cvekl, Wei Liu

Stem Cell Reports. 2016 May 10; 6(5): 743–756. Published online 2016 Apr 28. doi: 10.1016/j.stemcr.2016.03.011

PMCID:: PMC4939656

Abstract Article PDF–5.4M

Select item 471702513.

Enhancement of migration and invasion of hepatoma cells via a Rho GTPase signaling pathway

De-Sheng Wang, Ke-Feng Dou, Kai-Zong Li, Zhen-Shun Song

World J Gastroenterol. 2004 Jan 15; 10(2): 299–302. Published online 2004 Jan 15. doi: 10.3748/wjg.v10.i2.299

PMCID:: PMC4717025

Abstract Article PDF–105K

Select item 443003314.

RhoA/ROCK1 regulates Avian Reovirus S1133-induced switch from autophagy to apoptosis

Ping-Yuan Lin, Ching-Dong Chang, Yo-Chia Chen, Wen-Ling Shih

BMC Vet Res. 2015; 11: 103. Published online 2015 May 6. doi: 10.1186/s12917-015-0417-6

PMCID:: PMC4430033

Abstract Article PDF–3.7M

Select item 430049415.

ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma

Marjon A Smit, Gianluca Maddalo, Kylie Greig, Linsey M Raaijmakers, Patricia A Possik, Bas van Breukelen, Salvatore Cappadona, Albert JR Heck, AF Maarten Altelaar, Daniel S Peeper

Mol Syst Biol. 2014 Dec; 10(12): 772. Published online 2014 Dec 23. doi: 10.15252/msb.20145450

PMCID:: PMC4300494

Abstract Article PDF–8.7M

Select item 423271416.

ROCK1 as a novel prognostic marker in vulvar cancer

Erica M Akagi, André M Lavorato-Rocha, Beatriz de Melo Maia, Iara S Rodrigues, Kátia C Carvalho, Monica M Stiepcich, Glauco Baiocchi, Yukie Sato-Kuwabara, Silvia R Rogatto, Fernando A Soares, Rafael M Rocha

BMC Cancer. 2014; 14: 822. Published online 2014 Nov 7. doi: 10.1186/1471-2407-14-822

PMCID:: PMC4232714

Abstract Article PDF–1.8M

Select item 394588217.

RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex

Fan Yao, Ling-Yun Long, Yue-Zhen Deng, Yuan-Yuan Feng, Guo-Yuan Ying, Wen-Dai Bao, Guo Li, Dong-Xian Guan, Yin-Qiu Zhu, Jing-Jing Li, Dong Xie

Cell Res. 2014 Mar; 24(3): 359–371. Published online 2013 Dec 10. doi: 10.1038/cr.2013.162

PMCID:: PMC3945882

Abstract Article PDF–3.0M

Select item 393129218.

The effect of ROCK-1 activity change on the adhesive and invasive ability of Y79 retinoblastoma cells

Jing Wang, Xiao-Hong Liu, Zi-Jian Yang, Bing Xie, Yi-Sheng Zhong

BMC Cancer. 2014; 14: 89. Published online 2014 Feb 14. doi: 10.1186/1471-2407-14-89

PMCID:: PMC3931292

Abstract Article PDF–636K

Select item 380708919.

Measurement of Rho-Associated Kinase (ROCK) Activity in Humans: Validity of Leukocyte p-MBS/t-MBS in Comparison with Vascular Response to Fasudil

Takaki Hata, Chikara Goto, Junko Soga, Takayuki Hidaka, Yuichi Fujii, Naomi Idei, Noritaka Fujimura, Tatsuya Maruhashi, Shinsuke Mikami, Yasuki Kihara, Kazuaki Chayama, Kensuke Noma, James K. Liao, Yukihito Higashi

Atherosclerosis. Author manuscript; available in PMC 2013 Oct 24.

Published in final edited form as: Atherosclerosis. 2011 Jan; 214(1): 117–121. Published online 2010 Oct 12. doi: 10.1016/j.atherosclerosis.2010.10.005

PMCID:: PMC3807089

Abstract Article PDF–610K

Select item 373404120.

Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot

Julian Palomino Doza, Ana Topf, Jamie Bentham, Shoumo Bhattacharya, Catherine Cosgrove, J David Brook, Javier Granados-Riveron, Frances A Bu’Lock, John O’Sullivan, A Graham Stuart, Jonathan Parsons, Caroline Relton, Judith Goodship, Deborah J Henderson, Bernard Keavney

BMC Genet. 2013; 14: 57. Published online 2013 Jun 19. doi: 10.1186/1471-2156-14-57

PMCID:: PMC3734041

Abstract Article PDF–320K

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PMC Links for Gene (Select 6093) (270)
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GAP Links for Gene (Select 6093) (2)
dbGaP
Homo sapiens genomic DNA; cDNA DKFZp564F112 (from clone DKFZp564F112)
Homo sapiens genomic DNA; cDNA DKFZp564F112 (from clone DKFZp564F112)
gi|4884238|emb|AL049987.1|

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