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Select item 72264911.

uL3 Mediated Nucleolar Stress Pathway as a New Mechanism of Action of Antiproliferative G-quadruplex TBA Derivatives in Colon Cancer Cells

Annalisa Pecoraro, Antonella Virgilio, Veronica Esposito, Aldo Galeone, Giulia Russo, Annapina Russo

Biomolecules. 2020 Apr; 10(4): 583. Published online 2020 Apr 10. doi: 10.3390/biom10040583

PMCID:: PMC7226491

Abstract Article PDF–1.6M

Select item 53725632.

Role of uL3 in Multidrug Resistance in p53-Mutated Lung Cancer Cells

Annapina Russo, Assunta Saide, Silvia Smaldone, Raffaella Faraonio, Giulia Russo

Int J Mol Sci. 2017 Mar; 18(3): 547. Published online 2017 Mar 3. doi: 10.3390/ijms18030547

PMCID:: PMC5372563

Abstract Article PDF–1.6M

Select item 42943883.

Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP

Davide Esposito, Elvira Crescenzi, Vinay Sagar, Fabrizio Loreni, Annapina Russo, Giulia Russo

Oncotarget. 2014 Nov; 5(22): 11737–11751. Published online 2014 Nov 28. doi: 10.18632/oncotarget.2591

PMCID:: PMC4294388

Abstract Article PDF–2.7M

Select item 99860624.

BAIAP2L1 accelerates breast cancer progression and chemoresistance by activating AKT signaling through binding with ribosomal protein L3

Ning Deng, Xiupeng Zhang, Yong Zhang

Cancer Sci. 2023 Mar; 114(3): 764–780. Published online 2022 Dec 1. doi: 10.1111/cas.15632

PMCID:: PMC9986062

Abstract Article PDF–15M

Select item 91771495.

METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance

Eriko Matsuura-Suzuki, Tadahiro Shimazu, Mari Takahashi, Kaoru Kotoshiba, Takehiro Suzuki, Kazuhiro Kashiwagi, Yoshihiro Sohtome, Mai Akakabe, Mikiko Sodeoka, Naoshi Dohmae, Takuhiro Ito, Yoichi Shinkai, Shintaro Iwasaki

eLife. 2022; 11: e72780. Published online 2022 Jun 8. doi: 10.7554/eLife.72780

PMCID:: PMC9177149

Abstract Article PDF–2.9M

Select item 80346396.

Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function

Jędrzej M Małecki, Marie-Francoise Odonohue, Yeji Kim, Magnus E Jakobsson, Luca Gessa, Rita Pinto, Jie Wu, Erna Davydova, Anders Moen, Jesper V Olsen, Bernd Thiede, Pierre-Emmanuel Gleizes, Sebastian A Leidel, Pål Ø Falnes

Nucleic Acids Res. 2021 Apr 6; 49(6): 3185–3203. Published online 2021 Mar 8. doi: 10.1093/nar/gkab088

PMCID:: PMC8034639

Abstract Article PDF–10M

Select item 78775617.

DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3

Xue Zhang, Jing Han, Li Feng, Lianghui Zhi, Da Jiang, Bin Yu, Zhenya Zhang, Bo Gao, Cong Zhang, Meng Li, Lianmei Zhao, Guiying Wang

Carcinogenesis. 2021 Jan; 42(1): 105–117. Published online 2020 Jun 12. doi: 10.1093/carcin/bgaa056

PMCID:: PMC7877561

Abstract Article PDF–1.4M

Select item 77959608.

S-Adenosyl-l-Methionine Overcomes uL3-Mediated Drug Resistance in p53 Deleted Colon Cancer Cells

Laura Mosca, Martina Pagano, Annalisa Pecoraro, Luigi Borzacchiello, Luigi Mele, Giovanna Cacciapuoti, Marina Porcelli, Giulia Russo, Annapina Russo

Int J Mol Sci. 2021 Jan; 22(1): 103. Published online 2020 Dec 24. doi: 10.3390/ijms22010103

PMCID:: PMC7795960

Abstract Article PDF–5.7M

Select item 53467449.

Enhancement of 5-FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles

Annapina Russo, Sara Maiolino, Valentina Pagliara, Francesca Ungaro, Fabiana Tatangelo, Alessandra Leone, Giulia Scalia, Alfredo Budillon, Fabiana Quaglia, Giulia Russo

Oncotarget. 2016 Nov 29; 7(48): 79670–79687. Published online 2016 Nov 8. doi: 10.18632/oncotarget.13216

PMCID:: PMC5346744

Abstract Article PDF–5.3M

Select item 522658610.

5-FU targets rpL3 to induce mitochondrial apoptosis via cystathionine-β-synthase in colon cancer cells lacking p53

Valentina Pagliara, Assunta Saide, Emma Mitidieri, Bianca Roberta d'Emmanuele di Villa, Raffaella Sorrentino, Giulia Russo, Annapina Russo

Oncotarget. 2016 Aug 2; 7(31): 50333–50348. Published online 2016 Jul 2. doi: 10.18632/oncotarget.10385

PMCID:: PMC5226586

Abstract Article PDF–6.1M

Select item 357052011.

Human rpL3 induces G₁/S arrest or apoptosis by modulating p21^waf1/cip1 levels in a p53-independent manner

Annapina Russo, Davide Esposito, Morena Catillo, Concetta Pietropaolo, Elvira Crescenzi, Giulia Russo

Cell Cycle. 2013 Jan 1; 12(1): 76–87. doi: 10.4161/cc.22963

PMCID:: PMC3570520

Abstract Article PDF–2.6M

Select item 681790012.

Ribosomal protein uL3 targets E2F1 and Cyclin D1 in cancer cell response to nucleolar stress

Annalisa Pecoraro, Pietro Carotenuto, Giulia Russo, Annapina Russo

Sci Rep. 2019; 9: 15431. Published online 2019 Oct 28. doi: 10.1038/s41598-019-51723-7

PMCID:: PMC6817900

Abstract Article PDF–2.9M

Select item 317720613.

Autoregulatory circuit of human rpL3 expression requires hnRNP H1, NPM and KHSRP

Annapina Russo, Morena Catillo, Davide Esposito, Paola Briata, Concetta Pietropaolo, Giulia Russo

Nucleic Acids Res. 2011 Sep; 39(17): 7576–7585. Published online 2011 Jun 25. doi: 10.1093/nar/gkr461

Correction in:: Nucleic Acids Res. 2017 Dec 1; 45(21): 12600.

Correction in:: Nucleic Acids Res. 2022 Nov 11; 50(20): 11999.

PMCID:: PMC3177206

Abstract Article PDF–631K

Select item 452530714.

The DHX33 RNA Helicase Promotes mRNA Translation Initiation

Yandong Zhang, Jin You, Xingshun Wang, Jason Weber

Mol Cell Biol. 2015 Sep; 35(17): 2918–2931. Prepublished online 2015 Jun 22. Published online 2015 Aug 4. doi: 10.1128/MCB.00315-15

PMCID:: PMC4525307

Abstract Article PDF–2.6M

Select item 163636615.

NOP132 is required for proper nucleolus localization of DEAD-box RNA helicase DDX47

Takeshi Sekiguchi, Toshiya Hayano, Mitsuaki Yanagida, Nobuhiro Takahashi, Takeharu Nishimoto

Nucleic Acids Res. 2006 Sep; 34(16): 4593–4608. Published online 2006 Sep 8. doi: 10.1093/nar/gkl603

PMCID:: PMC1636366

Abstract Article PDF–1.1M

Select item 825766016.

USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-β2 transcription

Xiaohua Jie, William Pat Fong, Rui Zhou, Ye Zhao, Yingchao Zhao, Rui Meng, Sheng Zhang, Xiaorong Dong, Tao Zhang, Kunyu Yang, Gang Wu, Shuangbing Xu

Cell Death Differ. 2021 Jul; 28(7): 2095–2111. Published online 2021 Feb 8. doi: 10.1038/s41418-021-00740-z

PMCID:: PMC8257660

Abstract Article PDF–6.4M

Select item 542340517.

Ubiquitination of the spliceosome auxiliary factor hnRNPA1 by TRAF6 links chronic innate immune signaling with hematopoietic defects and myelodysplasia

Jing Fang, Lyndsey Bolanos, Kwangmin Choi, Xiaona Liu, Susanne Christie, Shailaja Akunuru, Rupali Kumar, Dehua Wang, Xiaoting Chen, Ken D. Greis, Peter Stoilov, Marie-Dominique Filippi, Jaroslaw P. Maciejewski, Guillermo Garcia-Manero, Matthew T. Weirauch, Nathan Salamonis, Hartmut Geiger, Yi Zheng, Daniel T. Starczynowski

Nat Immunol. Author manuscript; available in PMC 2017 Jun 26.

Published in final edited form as: Nat Immunol. 2017 Feb; 18(2): 236–245. Published online 2016 Dec 26. doi: 10.1038/ni.3654

Correction in:: Nat Immunol. 2017 Mar 22; 18(4): 474.

PMCID:: PMC5423405

Abstract Article PDF–2.9M

Select item 633279118.

OTUB2 stabilizes U2AF2 to promote the Warburg effect and tumorigenesis via the AKT/mTOR signaling pathway in non-small cell lung cancer

Jing Li, Dongdong Cheng, Miaoxin Zhu, Huajian Yu, Zhen Pan, Lei Liu, Qin Geng, Hongyu Pan, Mingxia Yan, Ming Yao

Theranostics. 2019; 9(1): 179–195. Published online 2019 Jan 1. doi: 10.7150/thno.29545

PMCID:: PMC6332791

Abstract Article PDF–3.3M

Select item 274240219.

Shwachman-Bodian Diamond syndrome is a multi-functional protein implicated in cellular stress responses

Heather L. Ball, Bing Zhang, J. Jacob Riches, Rikesh Gandhi, Jing Li, Johanna M. Rommens, Jeremy S. Myers

Hum Mol Genet. 2009 Oct 1; 18(19): 3684–3695. Published online 2009 Jul 14. doi: 10.1093/hmg/ddp316

PMCID:: PMC2742402

Abstract Article PDF–366K

Select item 186613220.

NFX1-123 and Poly(A) Binding Proteins Synergistically Augment Activation of Telomerase in Human Papillomavirus Type 16 E6-Expressing Cells

Rachel A. Katzenellenbogen, Erin M. Egelkrout, Portia Vliet-Gregg, Lindy C. Gewin, Philip R. Gafken, Denise A. Galloway

J Virol. 2007 Apr; 81(8): 3786–3796. Published online 2007 Jan 31. doi: 10.1128/JVI.02007-06

PMCID:: PMC1866132

Abstract Article PDF–554K

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PMC Links for Gene (Select 6122) (209)
PMC
leucine-rich repeat and calponin homology domain-containing protein 4 isoform X2...
leucine-rich repeat and calponin homology domain-containing protein 4 isoform X2 [Homo sapiens]
gi|2462614416|ref|XP_054214207.1|

Protein
YJR146W [Saccharomyces cerevisiae S288C]
YJR146W [Saccharomyces cerevisiae S288C]
Gene ID:853611

Gene
DC181509 Xenopus tropicalis embryo gastrula Xenopus tropicalis cDNA clone st60g1...
DC181509 Xenopus tropicalis embryo gastrula Xenopus tropicalis cDNA clone st60g14 5', mRNA sequence
gi|119158254|gnl|dbEST|43422728|dbj 1509.1|

Nucleotide
AGENCOURT_103351693 NICHD_XGC_tropInt_66 Xenopus tropicalis cDNA clone IMAGE:896...
AGENCOURT_103351693 NICHD_XGC_tropInt_66 Xenopus tropicalis cDNA clone IMAGE:8962361 5', mRNA sequence
gi|126534318|gnl|dbEST|45052324|gb| 043.1|

Nucleotide

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