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Select item 104856371.

Quantitative proteomics and phosphoproteomics of PP2A-PPP2R5D variants reveal deregulation of RPS6 phosphorylation via converging signaling cascades

Kali A. Smolen, Cinta M. Papke, Mark R. Swingle, Alla Musiyenko, Chenchen Li, E. Alan Salter, Ashley D. Camp, Richard E. Honkanen, Arminja N. Kettenbach

J Biol Chem. 2023 Sep; 299(9): 105154. Published online 2023 Aug 10. doi: 10.1016/j.jbc.2023.105154

PMCID:: PMC10485637

Abstract Article PDF–2.9M

Select item 86827712.

Phosphorylation of ribosomal protein S6 differentially affects mRNA translation based on ORF length

Jonathan Bohlen, Mykola Roiuk, Aurelio A Teleman

Nucleic Acids Res. 2021 Dec 16; 49(22): 13062–13074. Published online 2021 Dec 6. doi: 10.1093/nar/gkab1157

PMCID:: PMC8682771

Abstract Article PDF–17M

Select item 74577593.

Knockdown of ribosomal protein S6 suppresses proliferation, migration, and invasion in epithelial ovarian cancer

Xueqing Yang, Luxi Xu, Yu-e Yang, Chang Xiong, Jinjin Yu, Yuan Wang, Yaying Lin

J Ovarian Res. 2020; 13: 100. Published online 2020 Aug 31. doi: 10.1186/s13048-020-00707-7

PMCID:: PMC7457759

Abstract Article PDF–2.3M

Select item 72931024.

Ribosomal protein S6 promotes stem‐like characters in glioma cells

Yuki Shirakawa, Takuichiro Hide, Michiko Yamaoka, Yuki Ito, Naofumi Ito, Kunimasa Ohta, Naoki Shinojima, Akitake Mukasa, Hideyuki Saito, Hirofumi Jono

Cancer Sci. 2020 Jun; 111(6): 2041–2051. Published online 2020 Apr 30. doi: 10.1111/cas.14399

PMCID:: PMC7293102

Abstract Article PDF–2.2M

Select item 48080085.

The ribosomal protein S6 in renal cell carcinoma: functional relevance and potential as biomarker

Maximilian Knoll, Stephan Macher-Goeppinger, Jürgen Kopitz, Stefan Duensing, Sascha Pahernik, Markus Hohenfellner, Peter Schirmacher, Wilfried Roth

Oncotarget. 2016 Jan 5; 7(1): 418–432. Published online 2015 Oct 25. doi: 10.18632/oncotarget.6225

PMCID:: PMC4808008

Abstract Article PDF–3.1M

Select item 46181486.

Hyperphosphorylation of ribosomal protein S6 predicts unfavorable clinical survival in non-small cell lung cancer

Bojiang Chen, Zhi Tan, Jun Gao, Wei Wu, Lida Liu, Wei Jin, Yidan Cao, Shuang Zhao, Wen Zhang, Zhixin Qiu, Dan Liu, Xianming Mo, Weimin Li

J Exp Clin Cancer Res. 2015; 34: 126. Published online 2015 Oct 21. doi: 10.1186/s13046-015-0239-1

PMCID:: PMC4618148

Abstract Article PDF–3.1M

Select item 41028167.

Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers

Chong-kui Sun, Fan Zhang, Tao Xiang, Qianming Chen, Tej K. Pandita, Yuping Huang, Mickey C.T. Hu, Qin Yang

Oncotarget. 2014 May; 5(10): 3375–3385. Published online 2014 May 8. doi: 10.18632/oncotarget.1952

PMCID:: PMC4102816

Abstract Article PDF–3.7M

Select item 34280378.

A Novel Origin for Granulovacuolar Degeneration in Aging and Alzheimer’s Disease: Parallels to Stress Granules

Rudy J. Castellani, Yashi Gupta, Baiyang Sheng, Sandra L. Siedlak, Peggy L.R. Harris, Jeff M. Coller, George Perry, Hyoung-gon Lee, Massimo Tabaton, Mark A. Smith, Xinglong Wang, Xiongwei Zhu

Lab Invest. Author manuscript; available in PMC 2012 Aug 27.

Published in final edited form as: Lab Invest. 2011 Dec; 91(12): 1777–1786. Published online 2011 Oct 3. doi: 10.1038/labinvest.2011.149

PMCID:: PMC3428037

Abstract Article PDF–1.5M

Select item 32276809.

Ribosomal protein S6 is highly expressed in non-Hodgkin lymphoma and associates with mRNA containing a 5′ terminal oligopyrimidine tract

PR Hagner, K Mazan-Mamczarz, B Dai, EM Balzer, S Corl, SS Martin, XF Zhao, RB Gartenhaus

Oncogene. Author manuscript; available in PMC 2011 Nov 30.

Published in final edited form as: Oncogene. 2011 Mar 31; 30(13): 1531–1541. Published online 2010 Nov 22. doi: 10.1038/onc.2010.533

PMCID:: PMC3227680

Abstract Article PDF–2.7M

Select item 305732910.

Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma

Diego F. Calvisi, Chunmei Wang, Coral Ho, Sara Ladu, Susie A. Lee, Sandra Mattu, Giulia Destefanis, Salvatore Delogu, Antje Zimmermann, Johan Ericsson, Stefania Brozzetti, Tommaso Staniscia, Xin Chen, Frank Dombrowski, Matthias Evert

Gastroenterology. Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: Gastroenterology. 2011 Mar; 140(3): 1071–1083.e5. Published online 2010 Dec 11. doi: 10.1053/j.gastro.2010.12.006

PMCID:: PMC3057329

Abstract Article PDF–3.8M

Select item 304875011.

Regulation of Ribosomal Protein S6 Phosphorylation by Casein Kinase 1 and Protein Phosphatase 1

John A. Hutchinson, Naval P. Shanware, Haeyoon Chang, Randal S. Tibbetts

J Biol Chem. 2011 Mar 11; 286(10): 8688–8696. Published online 2011 Jan 13. doi: 10.1074/jbc.M110.141754

PMCID:: PMC3048750

Abstract Article PDF–1.6M

Select item 744753112.

Phosphorylated ribosomal S6 (p-rpS6) as a post-treatment indicator of HER2 signalling targeted drug resistance

Gloria Yang-Kolodji, Shannon M. Mumenthaler, Arjun Mehta, Lingyun Ji, Debu Tripathy

Biomarkers. Author manuscript; available in PMC 2020 Aug 25.

Published in final edited form as: Biomarkers. 2015; 20(5): 313–322. doi: 10.3109/1354750X.2015.1068865

PMCID:: PMC7447531

Abstract Article PDF–1004K

Select item 726903513.

Capturing the Mechanism Underlying TOP mRNA Binding to LARP1

Kevin C. Cassidy, Roni M. Lahr, Jesse C. Kaminsky, Stephanie Mack, Bruno D. Fonseca, Subha R. Das, Andrea J. Berman, Jacob D. Durrant

Structure. Author manuscript; available in PMC 2020 Dec 3.

Published in final edited form as: Structure. 2019 Dec 3; 27(12): 1771–1781.e5. Published online 2019 Oct 31. doi: 10.1016/j.str.2019.10.006

PMCID:: PMC7269035

Abstract Article PDF–1.7M

Select item 710601414.

Nsp1 proteins of group I and SARS coronaviruses share structural and functional similarities

Yongjin Wang, Huiling Shi, Pascal Rigolet, Nannan Wu, Lichen Zhu, Xu-Guang Xi, Astrid Vabret, Xiaoming Wang, Tianhou Wang

Infect Genet Evol. 2010 Oct; 10(7): 919–924. Published online 2010 Jun 2. doi: 10.1016/j.meegid.2010.05.014

PMCID:: PMC7106014

Abstract Article PDF–411K

Select item 647652515.

Novel AU-rich proximal UTR sequences (APS) enhance CXCL8 synthesis upon the induction of rpS6 phosphorylation

Zhiwei Ang, Ricky Abdi Gunawan Koean, Jun Zhi Er, Li Ting Lee, John Kit Chung Tam, Huili Guo, Jeak Ling Ding

PLoS Genet. 2019 Apr; 15(4): e1008077. Published online 2019 Apr 10. doi: 10.1371/journal.pgen.1008077

PMCID:: PMC6476525

Abstract Article PDF–4.4M

Select item 504543316.

Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas

Darío García-Carracedo, Maria Ángeles Villaronga, Saúl Álvarez-Teijeiro, Francisco Hermida-Prado, Iñigo Santamaría, Eva Allonca, Laura Suárez-Fernández, Maria Victoria Gonzalez, Milagros Balbín, Aurora Astudillo, Pablo Martínez-Camblor, Gloria H. Su, Juan Pablo Rodrigo, Juana María García-Pedrero

Oncotarget. 2016 May 17; 7(20): 29780–29793. Published online 2016 Apr 23. doi: 10.18632/oncotarget.8957

PMCID:: PMC5045433

Abstract Article PDF–2.9M

Select item 421225717.

Resistance to Selumetinib (AZD6244) in Colorectal Cancer Cell Lines is Mediated by p70S6K and RPS6 Activation

Silvina Grasso, Elena Tristante, Miguel Saceda, Pablo Carbonell, Leticia Mayor-López, Mar Carballo-Santana, Estefanía Carrasco-García, Lourdes Rocamora-Reverte, Pilar García-Morales, Fernando Carballo, José A. Ferragut, Isabel Martínez-Lacaci

Neoplasia. 2014 Oct; 16(10): 845–860. Published online 2014 Oct 23. doi: 10.1016/j.neo.2014.08.011

PMCID:: PMC4212257

Abstract Article PDF–1.7M

Select item 404134018.

Phosphorylation of mTOR and S6RP predicts the efficacy of everolimus in patients with metastatic renal cell carcinoma

Siming Li, Yan Kong, Lu Si, Zhihong Chi, Chuanliang Cui, Xinan Sheng, Jun Guo

BMC Cancer. 2014; 14: 376. Published online 2014 May 28. doi: 10.1186/1471-2407-14-376

PMCID:: PMC4041340

Abstract Article PDF–2.4M

Select item 316575219.

Ribosomal Protein S6 Interacts with the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus

Wuguo Chen, Dirk P. Dittmer

J Virol. 2011 Sep; 85(18): 9495–9505. doi: 10.1128/JVI.02620-10

PMCID:: PMC3165752

Abstract Article PDF–922K

Select item 182050220.

hDREF Regulates Cell Proliferation and Expression of Ribosomal Protein Genes

Daisuke Yamashita, Yukako Sano, Yuka Adachi, Yuma Okamoto, Hirotaka Osada, Takashi Takahashi, Tomohiro Yamaguchi, Takashi Osumi, Fumiko Hirose

Mol Cell Biol. 2007 Mar; 27(6): 2003–2013. Published online 2007 Jan 12. doi: 10.1128/MCB.01462-06

PMCID:: PMC1820502

Abstract Article PDF–467K

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PMC Links for Gene (Select 6194) (229)
PMC
Homo sapiens mRNA; cDNA DKFZp762B162 (from clone DKFZp762B162)
Homo sapiens mRNA; cDNA DKFZp762B162 (from clone DKFZp762B162)
gi|21732982|emb|AL832418.1|

Nucleotide
gamma-aminobutyric acid type B receptor subunit 1 isoform X2 [Homo sapiens]
gamma-aminobutyric acid type B receptor subunit 1 isoform X2 [Homo sapiens]
gi|2462493239|ref|XP_054186219.1|

Protein
PREDICTED: Homo sapiens gamma-aminobutyric acid type B receptor subunit 1 (GABBR...
PREDICTED: Homo sapiens gamma-aminobutyric acid type B receptor subunit 1 (GABBR1), transcript variant X7, mRNA
gi|2462494882|ref|XM_054331029.1|

Nucleotide

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