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Items: 1 to 20 of 96

1.
UBE2O promotes hepatocellular carcinoma cell proliferation and invasion by regulating the AMPKα2/mTOR pathway
Zhan Shi, Runkun Liu, Qiliang Lu, Zhi Zeng, Yang Liu, Junjun Zhao, Xin Liu, Lijie Li, Hui Huang, Yingmin Yao, Dongsheng Huang, Qiuran Xu
Int J Med Sci. 2021; 18(16): 3749–3758. Published online 2021 Oct 11. doi: 10.7150/ijms.63220
PMCID:
PMC8579295
AbstractArticlePDF–2.0M
2.
UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop
Xu Liu, Fei Ma, Chunxiao Liu, Kaiyuan Zhu, Wenjie Li, Yuting Xu, Ge Li, Zhenbo Niu, Jiaxin Liu, Du Chen, Zhigao Li, Yingqiang Fu, Cheng Qian
Cell Death Dis. 2020 Jan; 11(1): 10. Published online 2020 Jan 6. doi: 10.1038/s41419-019-2194-9
PMCID:
PMC6944706
AbstractArticlePDF–4.0M
3.
UBE2O is a quality control factor for orphans of multi-protein complexes
Kota Yanagitani, Szymon Juszkiewicz, Ramanujan S. Hegde
Science. Author manuscript; available in PMC 2018 Feb 4.
Published in final edited form as: Science. 2017 Aug 4; 357(6350): 472–475. doi: 10.1126/science.aan0178
PMCID:
PMC5549844
AbstractArticlePDF–1.5M
4.
UBE2O targets Mxi1 for ubiquitination and degradation to promote lung cancer progression and radioresistance
Yumei Huang, Xijie Yang, Yanwei Lu, Ye Zhao, Rui Meng, Sheng Zhang, Xiaorong Dong, Shuangbing Xu, Gang Wu
Cell Death Differ. 2021 Feb; 28(2): 671–684. Published online 2020 Sep 8. doi: 10.1038/s41418-020-00616-8
PMCID:
PMC7862231
AbstractArticlePDF–4.1M
5.
Saliva exosomes-derived UBE2O mRNA promotes angiogenesis in cutaneous wounds by targeting SMAD6
Bobin Mi, Lang Chen, Yuan Xiong, Chenchen Yan, Hang Xue, Adriana C. Panayi, Jing Liu, Liangcong Hu, Yiqiang Hu, Faqi Cao, Yun Sun, Wu Zhou, Guohui Liu
J Nanobiotechnology. 2020; 18: 68. Published online 2020 May 6. doi: 10.1186/s12951-020-00624-3
PMCID:
PMC7203970
AbstractArticlePDF–5.3M
6.
Hypoxia-induced exosomal circPDK1 promotes pancreatic cancer glycolysis via c-myc activation by modulating miR-628-3p/BPTF axis and degrading BIN1
Jiewei Lin, Xinjing Wang, Shuyu Zhai, Minmin Shi, Chenghong Peng, Xiaxing Deng, Da Fu, Jiancheng Wang, Baiyong Shen
J Hematol Oncol. 2022; 15: 128. Published online 2022 Sep 6. doi: 10.1186/s13045-022-01348-7
PMCID:
PMC9450374
AbstractArticlePDF–10M
7.
The N‐end rule ubiquitin ligase UBR2 mediates NLRP1B inflammasome activation by anthrax lethal toxin
Hao Xu, Jianjin Shi, Hang Gao, Ying Liu, Zhenxiao Yang, Feng Shao, Na Dong
EMBO J. 2019 Jul 1; 38(13): e101996. Published online 2019 May 6. doi: 10.15252/embj.2019101996
PMCID:
PMC6600268
AbstractArticlePDF–1.8M
8.
The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis
Yujia Xu, Zubin Zhang, Jie Li, Jiefei Tong, Biyin Cao, Paul Taylor, Xiaowen Tang, Depei Wu, Michael F. Moran, Yuanying Zeng, Xinliang Mao
J Hematol Oncol. 2017; 10: 132. Published online 2017 Jul 3. doi: 10.1186/s13045-017-0499-7
PMCID:
PMC5496436
AbstractArticlePDF–3.5M
9.
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1
Xiaotong Cen, Qing Chen, Bin Wang, Hongjie Xu, Xu Wang, Yixia Ling, Xiaofei Zhang, Dajiang Qin
Cell Commun Signal. 2022; 20: 191. Published online 2022 Nov 28. doi: 10.1186/s12964-022-00996-z
PMCID:
PMC9703712
AbstractArticlePDF–5.9M
10.
A muscle-specific UBE2O/AMPKα2 axis promotes insulin resistance and metabolic syndrome in obesity
Isabelle K. Vila, Mi Kyung Park, Stephanie Rebecca Setijono, Yixin Yao, Hyejin Kim, Pierre-Marie Badin, Sekyu Choi, Vihang Narkar, Sung-Woo Choi, Jongkyeong Chung, Cedric Moro, Su Jung Song, Min Sup Song
JCI Insight. 2019 Jul 11; 4(13): e128269. Published online 2019 Jul 11. doi: 10.1172/jci.insight.128269
PMCID:
PMC6629239
AbstractArticlePDF–7.8M
11.
Mechanism of client selection by the protein quality control factor UBE2O
Matthew C.J. Yip, Samantha F. Sedor, Sichen Shao
Nat Struct Mol Biol. Author manuscript; available in PMC 2023 Feb 1.
Published in final edited form as: Nat Struct Mol Biol. 2022 Aug; 29(8): 774–780. Published online 2022 Aug 1. doi: 10.1038/s41594-022-00807-6
PMCID:
PMC9526450
AbstractArticlePDF–4.5M
12.
A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis
Jessica D. Kessler, Kristopher T. Kahle, Tingting Sun, Kristen L. Meerbrey, Michael R. Schlabach, Earlene M. Schmitt, Samuel O. Skinner, Qikai Xu, Mamie Z. Li, Zachary C. Hartman, Mitchell Rao, Peng Yu, Rocio Dominguez-Vidana, Anthony C. Liang, Nicole L. Solimini, Ronald J. Bernardi, Bing Yu, Tiffany Hsu, Ido Golding, Ji Luo, C. Kent Osborne, Chad J. Creighton, Susan G. Hilsenbeck, Rachel Schiff, Chad A. Shaw, Stephen J. Elledge, Thomas F. Westbrook
Science. Author manuscript; available in PMC 2014 Jun 16.
Published in final edited form as: Science. 2012 Jan 20; 335(6066): 348–353. Published online 2011 Dec 8. doi: 10.1126/science.1212728
PMCID:
PMC4059214
AbstractArticlePDF–1.1M
13.
UBE2O negatively regulates TRAF6-mediated NF-κB activation by inhibiting TRAF6 polyubiquitination
Xiaofei Zhang, Juan Zhang, Long Zhang, Hans van Dam, Peter ten Dijke
Cell Res. 2013 Mar; 23(3): 366–377. Published online 2013 Feb 5. doi: 10.1038/cr.2013.21
PMCID:
PMC3587711
AbstractArticlePDF–1.2M
14.
Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6
Xiaofei Zhang, Juan Zhang, Andreas Bauer, Long Zhang, Douglas W Selinger, Chris X Lu, Peter ten Dijke
EMBO J. 2013 Apr 3; 32(7): 996–1007. Published online 2013 Mar 1. doi: 10.1038/emboj.2013.38
PMCID:
PMC3616286
AbstractArticlePDF–2.3M
15.
Regulation of WASH-Dependent Actin Polymerization and Protein Trafficking by Ubiquitination
Yi-Heng Hao, Jennifer M. Doyle, Saumya Ramanathan, Timothy S. Gomez, Da Jia, Ming Xu, Zhijian J. Chen, Daniel D. Billadeau, Michael K. Rosen, Patrick Ryan Potts
Cell. Author manuscript; available in PMC 2013 Aug 28.
Published in final edited form as: Cell. 2013 Feb 28; 152(5): 1051–1064. doi: 10.1016/j.cell.2013.01.051
PMCID:
PMC3640276
AbstractArticlePDF–6.0M
16.
BAP1 maintains chromosome stability by stabilizing DIDO1 in renal cell carcinoma
Jiantao Xiao, Ruhan Zhang, Jingtao Peng, Zhonghua Yang
Am J Cancer Res. 2020; 10(5): 1455–1466. Published online 2020 May 1.
PMCID:
PMC7269789
AbstractArticlePDF–1.4M
17.
ARRDC1 and ARRDC3 act as tumor suppressors in renal cell carcinoma by facilitating YAP1 degradation
Jiantao xiao, Qing Shi, Weiguo Li, Xingyu Mu, Jintao Peng, Mingzi Li, Mulin Chen, Huabing Huang, Chenji Wang, Kun Gao, Jie Fan
Am J Cancer Res. 2018; 8(1): 132–143. Published online 2018 Jan 1.
PMCID:
PMC5794727
AbstractArticlePDF–1.4M
18.
The MALDI-TOF E2/E3 Ligase Assay as Universal Tool for Drug Discovery in the Ubiquitin Pathway
Virginia De Cesare, Clare Johnson, Victoria Barlow, James Hastie, Axel Knebel, Matthias Trost
Cell Chem Biol. 2018 Sep 20; 25(9): 1117–1127.e4. doi: 10.1016/j.chembiol.2018.06.004
PMCID:
PMC6162346
AbstractArticle
19.
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
Agne Kazlauskaite, Van Kelly, Clare Johnson, Carla Baillie, C. James Hastie, Mark Peggie, Thomas Macartney, Helen I. Woodroof, Dario R. Alessi, Patrick G. A. Pedrioli, Miratul M. K. Muqit
Open Biol. 2014 Mar; 4(3): 130213. Published online 2014 Mar 19. doi: 10.1098/rsob.130213
PMCID:
PMC3971407
AbstractArticlePDF–1.7M
20.
A UBE2O-AMPKα2 Axis That Promotes Tumor Initiation and Progression Offers Opportunities for Therapy
Isabelle K. Vila, Yixin Yao, Goeun Kim, Weiya Xia, Hyejin Kim, Sun-Joong Kim, Mi Kyung Park, James P. Hwang, Enrique González Billalabeitia, Mien-Chie Hung, Su Jung Song, Min Sup Song
Cancer Cell. Author manuscript; available in PMC 2018 Feb 13.
Published in final edited form as: Cancer Cell. 2017 Feb 13; 31(2): 208–224. Published online 2017 Feb 2. doi: 10.1016/j.ccell.2017.01.003
PMCID:
PMC5463996
AbstractArticlePDF–2.6M

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