PMC Links for Gene (Select 64101) - PMC

Select item 101061531.

Leucine-rich repeats containing 4 protein (LRRC4) in memory, psychoneurosis, and glioblastoma

Kun Deng, Minghua Wu

Chin Med J (Engl) 2023 Jan 5; 136(1): 4–12. Published online 2023 Feb 10. doi: 10.1097/CM9.0000000000002441

PMCID:: PMC10106153

Abstract Article PDF–2.2M

Select item 25886342.

Promoter Hypermethylation-mediated Inactivation of LRRC4 in Gliomas

Zuping Zhang, Dan Li, Minghua Wu, Bo Xiang, Li Wang, Ming Zhou, Pan Chen, Xiaoling Li, Shourong Shen, Guiyuan Li

BMC Mol Biol. 2008; 9: 99. Published online 2008 Nov 3. doi: 10.1186/1471-2199-9-99

PMCID:: PMC2588634

Abstract Article PDF–541K

Select item 53565753.

Low expression of miR-381 is a favorite prognosis factor and enhances the chemosensitivity of osteosarcoma

Yunchao Li, Chunhua Zhao, Zhibin Yu, Jiarui Chen, Xiaoling She, Peiyao Li, Changhong Liu, Yan Zhang, Jianbo Feng, Haijuan Fu, Bing Wang, Lei Kuang, Lei Li, Guohua Lv, Minghua Wu

Oncotarget. 2016 Oct 18; 7(42): 68585–68596. Published online 2016 Sep 6. doi: 10.18632/oncotarget.11861

PMCID:: PMC5356575

Abstract Article PDF–12M

Select item 72699094.

Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide

Jianbo Feng, Yan Zhang, Xing Ren, Di Li, Haijuan Fu, Changhong Liu, Wen Zhou, Qing Liu, Qiang Liu, Minghua Wu

Oncogene. 2020; 39(23): 4551–4566. Published online 2020 May 5. doi: 10.1038/s41388-020-1312-6

PMCID:: PMC7269909

Abstract Article PDF–6.1M

Select item 51232855.

The D Domain of LRRC4 anchors ERK1/2 in the cytoplasm and competitively inhibits MEK/ERK activation in glioma cells

Zeyou Wang, Qin Guo, Rong Wang, Gang Xu, Peiyao Li, Yingnan Sun, Xiaoling She, Qiang Liu, Qiong Chen, Zhibin Yu, Changhong Liu, Jing Xiong, Guiyuan Li, Minghua Wu

J Hematol Oncol. 2016; 9: 130. Published online 2016 Nov 25. doi: 10.1186/s13045-016-0355-1

PMCID:: PMC5123285

Abstract Article PDF–2.3M

Select item 15252336.

LRRC4, a Putative Tumor Suppressor Gene, Requires a Functional Leucine-rich Repeat Cassette Domain to Inhibit Proliferation of Glioma Cells In Vitro by Modulating the Extracellular Signal-regulated Kinase/Protein Kinase B/Nuclear Factor-κB Pathway

Minghua Wu, Chen Huang, Kai Gan, He Huang, Qiong Chen, Jue Ouyang, Yunlian Tang, Xiaoling Li, Yixin Yang, Houde Zhou, Yanhong Zhou, Zhaoyang Zeng, Lan Xiao, Dan Li, Ke Tang, Shourong Shen, Guiyuan Li

Mol Biol Cell. 2006 Aug; 17(8): 3534–3542. doi: 10.1091/mbc.E05-11-1082

PMCID:: PMC1525233

Abstract Article PDF–1007K

Select item 38802757.

Disturbing miR-182 and -381 Inhibits BRD7 Transcription and Glioma Growth by Directly Targeting LRRC4

Hailin Tang, Zeyou Wang, Qing Liu, Xiaoping Liu, Minghua Wu, Guiyuan Li

PLoS One. 2014; 9(1): e84146. Published online 2014 Jan 3. doi: 10.1371/journal.pone.0084146

PMCID:: PMC3880275

Abstract Article PDF–2.2M

Select item 32303788.

Structural basis for cell surface patterning through NetrinG–NGL interactions

Elena Seiradake, Charlotte H Coles, Pavel V Perestenko, Karl Harlos, Robert Andrew Jeffrey McIlhinney, Alexandru Radu Aricescu, Edith Yvonne Jones

EMBO J. 2011 Nov 2; 30(21): 4479–4488. Published online 2011 Sep 23. doi: 10.1038/emboj.2011.346

PMCID:: PMC3230378

Abstract Article PDF–1.6M

Select item 67729459.

Netrin-G1: a Novel Glycosyl Phosphatidylinositol-Linked Mammalian Netrin That Is Functionally Divergent from Classical Netrins

Toshiaki Nakashiba, Toshio Ikeda, Sachiko Nishimura, Kei Tashiro, Tasuku Honjo, Joseph G. Culotti, Shigeyoshi Itohara

J Neurosci. 2000 Sep 1; 20(17): 6540–6550. doi: 10.1523/JNEUROSCI.20-17-06540.2000

PMCID:: PMC6772945

Abstract Article PDF–829K

Select item 583609710.

FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration

Ella Fung, Carmen Richter, Hong‐Bin Yang, Isabell Schäffer, Roman Fischer, Benedikt M Kessler, Florian Bassermann, Vincenzo D'Angiolella

EMBO Rep. 2018 Mar; 19(3): e44799. Published online 2018 Jan 18. doi: 10.15252/embr.201744799

PMCID:: PMC5836097

Abstract Article PDF–1.9M

Select item 288296111.

Human Chromosome 7: DNA Sequence and Biology

Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui

Science. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423

PMCID:: PMC2882961

Abstract Article PDF–1.2M

Select item 40369712.

The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment

Hilary F. Clark, Austin L. Gurney, Evangeline Abaya, Kevin Baker, Daryl Baldwin, Jennifer Brush, Jian Chen, Bernard Chow, Clarissa Chui, Craig Crowley, Bridget Currell, Bethanne Deuel, Patrick Dowd, Dan Eaton, Jessica Foster, Christopher Grimaldi, Qimin Gu, Philip E. Hass, Sherry Heldens, Arthur Huang, Hok Seon Kim, Laura Klimowski, Yisheng Jin, Stephanie Johnson, James Lee, Lhney Lewis, Dongzhou Liao, Melanie Mark, Edward Robbie, Celina Sanchez, Jill Schoenfeld, Somasekar Seshagiri, Laura Simmons, Jennifer Singh, Victoria Smith, Jeremy Stinson, Alicia Vagts, Richard Vandlen, Colin Watanabe, David Wieand, Kathryn Woods, Ming-Hong Xie, Daniel Yansura, Sothy Yi, Guoying Yu, Jean Yuan, Min Zhang, Zemin Zhang, Audrey Goddard, William I. Wood, Paul Godowski

Genome Res. 2003 Oct; 13(10): 2265–2270. doi: 10.1101/gr.1293003

Correction in:: Genome Res. 2003 Dec; 13(12): 2759.

PMCID:: PMC403697

Abstract Article PDF–120K

Select item 934857613.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 1015161514.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011