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Items: 1 to 20 of 74

1.
Enthalpy–Entropy Compensation in the Promiscuous Interaction of an Intrinsically Disordered Protein with Homologous Protein Partners
Jaka Kragelj, Thibault Orand, Elise Delaforge, Laura Tengo, Martin Blackledge, Andrés Palencia, Malene Ringkjøbing Jensen
Biomolecules. 2021 Aug; 11(8): 1204. Published online 2021 Aug 13. doi: 10.3390/biom11081204
PMCID:
PMC8391806
AbstractArticlePDF–3.3M
2.
Downregulation of phosphorylated MKK4 is associated with a poor prognosis in colorectal cancer patients
Pu-Ning Wang, Jun Huang, Ying-Hua Duan, Jia-Min Zhou, Pin-Zhu Huang, Xin-Juan Fan, Yan Huang, Lei Wang, Huan-Liang Liu, Jian-Ping Wang, Mei-Jin Huang
Oncotarget. 2017 May 23; 8(21): 34352–34361. Published online 2017 Mar 11. doi: 10.18632/oncotarget.16128
PMCID:
PMC5470973
AbstractArticlePDF–8.2M
3.
Mitogen-Activated Protein Kinase Kinase 4 Gene Polymorphism and Cancer Risk
Peiliang Geng, Juanjuan Ou, Ganfeng Xie, Jianjun Li, Xiaoxin Zhao, Lisha Xiang, Yunmei Liao, Ning Wang, Houjie Liang
Medicine (Baltimore) 2015 Nov; 94(44): e0938. Published online 2015 Nov 6. doi: 10.1097/MD.0000000000000938
PMCID:
PMC4915862
AbstractArticlePDF–365K
4.
Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Promotes Human Prostate Cancer Metastasis
Janet M. Pavese, Irene M. Ogden, Eric A. Voll, Xiaoke Huang, Li Xu, Borko Jovanovic, Raymond C. Bergan
PLoS One. 2014; 9(7): e102289. Published online 2014 Jul 14. doi: 10.1371/journal.pone.0102289
PMCID:
PMC4096757
AbstractArticlePDF–3.2M
5.
The Association Between -1304T>G Polymorphism in the Promoter of Mitogen-Activated Protein Kinase Kinase 4 Gene and the Risk of Cervical Cancer in Chinese Population
Min Hu, Jian Zheng, Liyuan Zhang, Lan Jiang, Yonghe You, Mingjun Jiang, Hua Li
DNA Cell Biol. 2012 Jul; 31(7): 1167–1173. doi: 10.1089/dna.2011.1586
PMCID:
PMC3391489
AbstractArticlePDF–234K
6.
Analysis of the Mitogen-activated protein kinase kinase 4 (MAP2K4) tumor suppressor gene in ovarian cancer
Sally J Davis, David YH Choong, Manasa Ramakrishna, Georgina L Ryland, Ian G Campbell, Kylie L Gorringe
BMC Cancer. 2011; 11: 173. Published online 2011 May 17. doi: 10.1186/1471-2407-11-173
PMCID:
PMC3115913
AbstractArticlePDF–1.8M
7.
Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs
Bernard S. Marasa, Subramanya Srikantan, Kiyoshi Masuda, Kotb Abdelmohsen, Yuki Kuwano, Xiaoling Yang, Jennifer L. Martindale, Carrie W. Rinker-Schaeffer, Myriam Gorospe
Sci Signal. Author manuscript; available in PMC 2010 Apr 27.
Published in final edited form as: Sci Signal. 2009 Oct 27; 2(94): ra69. Published online 2009 Oct 27. doi: 10.1126/scisignal.2000442
PMCID:
PMC2770878
AbstractArticlePDF–2.9M
8.
MEK4 Function, Genistein Treatment, and Invasion of Human Prostate Cancer Cells
Li Xu, Yongzeng Ding, William J. Catalona, Ximing J. Yang, Wayne F. Anderson, Borko Jovanovic, Kenji Wellman, Jaqueline Killmer, Xiaoke Huang, Karl A. Scheidt, R. Bruce Montgomery, Raymond C. Bergan
J Natl Cancer Inst. 2009 Aug 19; 101(16): 1141–1155. Published online 2009 Aug 19. doi: 10.1093/jnci/djp227
PMCID:
PMC2728746
AbstractArticlePDF–1.2M
9.
Mitogen-Activated Protein Kinase Kinase 4/c-Jun NH2-Terminal Kinase Kinase 1 Protein Expression Is Subject to Translational Regulation in Prostate Cancer Cell Lines
Victoria L. Robinson, Ore Shalhav, Kristen Otto, Tomoko Kawai, Myriam Gorospe, Carrie W. Rinker-Schaeffer
Mol Cancer Res. Author manuscript; available in PMC 2009 Mar 1.
Published in final edited form as: Mol Cancer Res. 2008 Mar; 6(3): 501–508. doi: 10.1158/1541-7786.MCR-07-2075
PMCID:
PMC2435180
AbstractArticlePDF–1.4M
10.
MAP2K4 interacts with Vimentin to activate the PI3K/AKT pathway and promotes breast cancer pathogenesis
Shu Liu, Juan Huang, Yewei Zhang, Yiyi Liu, Shi Zuo, Rong Li
Aging (Albany NY) 2019 Nov 30; 11(22): 10697–10710. Published online 2019 Nov 25. doi: 10.18632/aging.102485
PMCID:
PMC6914392
AbstractArticlePDF–1.9M
11.
Orange is the new black: Kinases are the new master regulators of tumor suppression
Elvira An, John Brognard
IUBMB Life. 2019 Jun; 71(6): 738–748. Published online 2018 Dec 11. doi: 10.1002/iub.1981
PMCID:
PMC6563145
AbstractArticlePDF–1.2M
12.
Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancers
Filip Mundt, Sandeep Rajput, Shunqiang Li, Kelly Ruggles, Arshag D. Mooradian, Philipp Mertins, Michael A. Gillette, Karsten Krug, Zhanfang Guo, Jeremy Hoog, Petra Erdmann-Gilmore, Tina Primeau, Shixia Huang, Dean P. Edwards, Xiaowei Wang, Xuya Wang, Emily Kawaler, D R. Mani, Karl R. Clauser, Feng Gao, Jingqin Luo, Sherri R. Davies, Gary L. Johnson, Kuan-lin Huang, Christopher J. Yoon, Li Ding, David Fenyö, Matthew J. Ellis, R. Reid Townsend, Jason M. Held, Steven A. Carr, Cynthia X. Ma
Cancer Res. Author manuscript; available in PMC 2019 May 15.
Published in final edited form as: Cancer Res. 2018 May 15; 78(10): 2732–2746. Published online 2018 Feb 22. doi: 10.1158/0008-5472.CAN-17-1990
PMCID:
PMC5955814
AbstractArticlePDF–1.2M
13.
Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes
S J Kiddle, C J Steves, M Mehta, A Simmons, X Xu, S Newhouse, M Sattlecker, N J Ashton, C Bazenet, R Killick, J Adnan, E Westman, S Nelson, H Soininen, I Kloszewska, P Mecocci, M Tsolaki, B Vellas, C Curtis, G Breen, S C R Williams, S Lovestone, T D Spector, R J B Dobson
Transl Psychiatry. 2015 Jun; 5(6): e584. Published online 2015 Jun 16. doi: 10.1038/tp.2015.78
PMCID:
PMC4490288
AbstractArticlePDF–1007K
14.
JNK3 Enzyme Binding to Arrestin-3 Differentially Affects the Recruitment of Upstream Mitogen-activated Protein (MAP) Kinase Kinases
Xuanzhi Zhan, Tamer S. Kaoud, Seunghyi Kook, Kevin N. Dalby, Vsevolod V. Gurevich
J Biol Chem. 2013 Oct 4; 288(40): 28535–28547. Published online 2013 Aug 19. doi: 10.1074/jbc.M113.508085
PMCID:
PMC3789954
AbstractArticlePDF–1.5M
15.
JNK regulates binding of α-catenin to adherens junctions and cell-cell adhesion
Meng-Horng Lee, Roshan Padmashali, Piyush Koria, Stelios T. Andreadis
FASEB J. 2011 Feb; 25(2): 613–623. doi: 10.1096/fj.10-161380
PMCID:
PMC3023394
AbstractArticle
16.
PCAT19 Regulates the Proliferation and Apoptosis of Lung Cancer Cells by Inhibiting miR-25-3p via Targeting the MAP2K4 Signal Axis
Bing Wang, Shengrong Yang, Yang Jia, Jianru Yang, Kun Du, Yujie Luo, Yunhe Li, Zhenghong Wang, Yi Liu, Bing Zhu
Dis Markers. 2022; 2022: 2442094. Published online 2022 May 16. doi: 10.1155/2022/2442094
PMCID:
PMC9126706
AbstractArticlePDF–3.6M
17.
Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression
Xueran Chen, Aijun Hao, Xian Li, Kaiqin Ye, Chenggang Zhao, Haoran Yang, Huihui Ma, Lei Hu, Zhiyang Zhao, Lizhu Hu, Fang Ye, Qiuyan Sun, Huaman Zhang, Hongzhi Wang, Xuebiao Yao, Zhiyou Fang
Theranostics. 2020; 10(3): 998–1015. Published online 2020 Jan 1. doi: 10.7150/thno.40076
PMCID:
PMC6956818
AbstractArticlePDF–3.7M
18.
MicroRNA‐802 plays a tumour suppressive role in tongue squamous cell carcinoma through directly targeting MAP2K4
Xiaozhen Wu, Zuode Gong, Lanying Sun, Long Ma, Qibao Wang
Cell Prolif. 2017 Jun; 50(3): e12336. Published online 2017 Mar 20. doi: 10.1111/cpr.12336
PMCID:
PMC6529076
AbstractArticlePDF–901K
19.
Thioredoxin Activates MKK4-NFκB Pathway in a Redox-dependent Manner to Control Manganese Superoxide Dismutase Gene Expression in Endothelial Cells
Venkatesh Kundumani-Sridharan, Jaganathan Subramani, Kumuda C. Das
J Biol Chem. 2015 Jul 10; 290(28): 17505–17519. Published online 2015 May 31. doi: 10.1074/jbc.M115.660365
PMCID:
PMC4498085
AbstractArticlePDF–3.2M
20.
Genetic variants in Fas signaling pathway genes and risk of gastric cancer
Paula L. Hyland, Shih-Wen Lin, Nan Hu, Han Zhang, Lemin Wang, Hua Su, Chaoyu Wang, Ti Ding, Ze-Zhong Tang, Jin-Hu Fan, You-Lin Qiao, Xiaoqin Xiong, William Wheeler, Carol Giffen, Kai Yu, Jeff Yuenger, Laurie Burdett, Zhaoming Wang, Stephen J. Chanock, Margaret A. Tucker, Sanford M. Dawsey, Neal D. Freedman, Alisa M. Goldstein, Christian C. Abnet, Philip R Taylor
Int J Cancer. Author manuscript; available in PMC 2015 Feb 15.
Published in final edited form as: Int J Cancer. 2014 Feb 15; 134(4): 822–831. Published online 2013 Sep 11. doi: 10.1002/ijc.28415
PMCID:
PMC3858487
AbstractArticlePDF–423K

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