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Select item 86141201.

Colorectal cancer risk variants rs10161980 and rs7495132 are associated with cancer survival outcome by a recessive mode of inheritance

Yazhou He, Maria Timofeeva, Xiaomeng Zhang, Wei Xu, Xue Li, Farhat V. N. Din, Victoria Svinti, Susan M. Farrington, Harry Campbell, Malcolm G. Dunlop, Evropi Theodoratou

Int J Cancer. 2021 Jun 1; 148(11): 2774–2778. Published online 2021 Jan 23. doi: 10.1002/ijc.33465

PMCID:: PMC8614120

Article PDF–962K

Select item 60761522.

Cyclic adenosine monophosphate-regulated transcriptional co-activator 3 polymorphism in Chinese patients with acute coronary syndrome

Li Zhu, Yahui Wang, Jun Jiang, Ruifang Zhou, Jun Ye

Medicine (Baltimore) 2018 Jul; 97(27): e11382. Published online 2018 Jul 6. doi: 10.1097/MD.0000000000011382

PMCID:: PMC6076152

Article PDF–435K

Select item 31213493.

Role of cAMP-responsive Element-binding Protein (CREB)-regulated Transcription Coactivator 3 (CRTC3) in the Initiation of Mitochondrial Biogenesis and Stress Response in Liver Cells

Tin Aung Than, Huan Lou, Cheng Ji, Sanda Win, Neil Kaplowitz

J Biol Chem. 2011 Jun 24; 286(25): 22047–22054. Published online 2011 May 2. doi: 10.1074/jbc.M111.240481

PMCID:: PMC3121349

Article PDF–1.1M

Select item 54333504.

CORRELATION OF CRTC1/3-MAML2 FUSION STATUS, GRADE AND SURVIVAL IN MUCOEPIDERMOID CARCINOMA

Andrew C. Birkeland, Susan K. Foltin, Nicole L. Michmerhuizen, Rebecca C. Hoesli, Andrew J. Rosko, Serena Byrd, Megan Yanik, Jacques E. Nor, Carol R. Bradford, Mark E. Prince, Thomas E. Carey, Jonathan B. McHugh, Matthew E. Spector, J. Chad Brenner

Oral Oncol. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Oral Oncol. 2017 May; 68: 5–8. Published online 2017 Mar 10. doi: 10.1016/j.oraloncology.2017.02.025

PMCID:: PMC5433350

Article PDF–224K

Select item 15696745.

Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1α transcription and mitochondrial biogenesis in muscle cells

Zhidan Wu, Xueming Huang, Yajun Feng, Christoph Handschin, Yan Feng, P. Scott Gullicksen, Olivia Bare, Mark Labow, Bruce Spiegelman, Susan C. Stevenson

Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39): 14379–14384. Published online 2006 Sep 15. doi: 10.1073/pnas.0606714103

PMCID:: PMC1569674

Article PDF–1.2M

Select item 30257116.

The CREB Coactivator CRTC3 Links Catecholamine Signaling to Energy Balance

Youngsup Song, Judith Altarejos, Mark O. Goodarzi, Hiroshi Inoue, Xiuqing Guo, Rebecca Berdeaux, Jeong-Ho Kim, Jason Goode, Motoyuki Igata, Jose Paz, Meghan F. Hogan, Pankaj K. Singh, Naomi Goebel, Lili Vera, Nina Miller, Jinrui Cui, Michelle R. Jones, CHARGE Consortium, GIANT Consortium, Yii-Der I. Chen, Kent D. Taylor, Willa A. Hsueh, Jerome I. Rotter, Marc Montminy

Nature. Author manuscript; available in PMC 2011 Dec 16.

Published in final edited form as: Nature. 2010 Dec 16; 468(7326): 933–939. doi: 10.1038/nature09564

PMCID:: PMC3025711

Article PDF–1.6M

Select item 57990077.

14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs)

Tim Sonntag, Joan M. Vaughan, Marc Montminy

FEBS J. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: FEBS J. 2018 Feb; 285(3): 467–480. Published online 2018 Jan 9. doi: 10.1111/febs.14351

PMCID:: PMC5799007

Article PDF–2.3M

Select item 34794638.

Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

Kristopher Clark, Kirsty F. MacKenzie, Kasparas Petkevicius, Yosua Kristariyanto, Jiazhen Zhang, Hwan Geun Choi, Mark Peggie, Lorna Plater, Patrick G. A. Pedrioli, Ed McIver, Nathanael S. Gray, J. Simon C. Arthur, Philip Cohen

Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42): 16986–16991. Published online 2012 Oct 2. doi: 10.1073/pnas.1215450109

PMCID:: PMC3479463

Article PDF–946K

Select item 2187279.

Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells

Vadim Iourgenko, Wenjun Zhang, Craig Mickanin, Ira Daly, Can Jiang, Jonathan M. Hexham, Anthony P. Orth, Loren Miraglia, Jodi Meltzer, Dan Garza, Gung-Wei Chirn, Elizabeth McWhinnie, Dalia Cohen, Joanne Skelton, Robert Terry, Yang Yu, Dale Bodian, Frank P. Buxton, Jian Zhu, Chuanzheng Song, Mark A. Labow

Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21): 12147–12152. Published online 2003 Sep 23. doi: 10.1073/pnas.1932773100

PMCID:: PMC218727

Article PDF–651K

Select item 510833910.

MDM2 facilitates adipocyte differentiation through CRTC-mediated activation of STAT3

P Hallenborg, M Siersbæk, I Barrio-Hernandez, R Nielsen, K Kristiansen, S Mandrup, L Grøntved, B Blagoev

Cell Death Dis. 2016 Jun; 7(6): e2289. Published online 2016 Jun 30. doi: 10.1038/cddis.2016.188

PMCID:: PMC5108339

Article PDF–2.7M

Select item 631727911.

Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment

Tim Sonntag, Jelena Ostojić, Joan M. Vaughan, James J. Moresco, Young-Sil Yoon, John R. Yates, III, Marc Montminy

iScience. 2019 Jan 25; 11: 134–145. Published online 2018 Dec 19. doi: 10.1016/j.isci.2018.12.012

PMCID:: PMC6317279

Article PDF–6.2M

Select item 331901512.

Whole genome association scan for genetic polymorphisms influencing information processing speed

Michelle Luciano, Narelle K. Hansell, Jari Lahti, Gail Davies, Sarah E. Medland, Katri Räikkönen, Albert Tenesa, Elisabeth Widen, Kevin A. McGhee, Aarno Palotie, David Liewald, David J. Porteous, John M. Starr, Grant W. Montgomery, Nicholas G. Martin, Johan G. Eriksson, Margaret J. Wright, Ian J. Deary

Biol Psychol. Author manuscript; available in PMC 2012 Apr 4.

Published in final edited form as: Biol Psychol. 2011 Mar; 86(3): 193–202. Published online 2010 Dec 3. doi: 10.1016/j.biopsycho.2010.11.008

PMCID:: PMC3319015

Article PDF–322K

Select item 884482713.

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase

Zhifen Zhou, Yujing Li, Huimin Xu, Xiaowei Xie, Zibin He, Song Lin, Ruofei Li, Shouheng Jin, Jun Cui, Hai Hu, Feng Liu, Su Wu, Wenbin Ma, Zhou Songyang

iScience. 2022 Feb 18; 25(2): 103813. Published online 2022 Jan 25. doi: 10.1016/j.isci.2022.103813

PMCID:: PMC8844827

Article PDF–6.0M

Select item 636858414.

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer

Weimei Tang, Weijie Zhou, Li Xiang, Xiaosheng Wu, Pei Zhang, Jing Wang, Guangnan Liu, Wenjing Zhang, Ying Peng, Xiaoting Huang, Jianqun Cai, Yang Bai, Lan Bai, Wei Zhu, Hongxiang Gu, Jing Xiong, Chen Ye, Aimin Li, Side Liu, Jide Wang

Nat Commun. 2019; 10: 663. Published online 2019 Feb 8. doi: 10.1038/s41467-018-08225-3

PMCID:: PMC6368584

Article PDF–6.8M

Select item 743103015.

A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

David E. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M. White, Matthew J. O’Meara, Veronica V. Rezelj, Jeffrey Z. Guo, Danielle L. Swaney, Tia A. Tummino, Ruth Huettenhain, Robyn M. Kaake, Alicia L. Richards, Beril Tutuncuoglu, Helene Foussard, Jyoti Batra, Kelsey Haas, Maya Modak, Minkyu Kim, Paige Haas, Benjamin J. Polacco, Hannes Braberg, Jacqueline M. Fabius, Manon Eckhardt, Margaret Soucheray, Melanie J. Bennett, Merve Cakir, Michael J. McGregor, Qiongyu Li, Bjoern Meyer, Ferdinand Roesch, Thomas Vallet, Alice Mac Kain, Lisa Miorin, Elena Moreno, Zun Zar Chi Naing, Yuan Zhou, Shiming Peng, Ying Shi, Ziyang Zhang, Wenqi Shen, Ilsa T. Kirby, James E. Melnyk, John S. Chorba, Kevin Lou, Shizhong A. Dai, Inigo Barrio-Hernandez, Danish Memon, Claudia Hernandez-Armenta, Jiankun Lyu, Christopher J.P. Mathy, Tina Perica, Kala B. Pilla, Sai J. Ganesan, Daniel J. Saltzberg, Ramachandran Rakesh, Xi Liu, Sara B. Rosenthal, Lorenzo Calviello, Srivats Venkataramanan, Jose Liboy-Lugo, Yizhu Lin, Xi-Ping Huang, YongFeng Liu, Stephanie A. Wankowicz, Markus Bohn, Maliheh Safari, Fatima S. Ugur, Cassandra Koh, Nastaran Sadat Savar, Quang Dinh Tran, Djoshkun Shengjuler, Sabrina J Fletcher, Michael C. O’Neal, Yiming Cai, Jason C.J.Chang, David J. Broadhurst, Saker Klippsten, Phillip P. Sharp, Nicole A. Wenzell, Duygu Kuzuoglu, Hao-Yuan Wang, Raphael Trenker, Janet M. Young, Devin A. Cavero, Joseph Hiatt, Theodore L. Roth, Ujjwal Rathore, Advait Subramanian, Julia Noack, Mathieu Hubert, Robert M. Stroud, Alan D. Frankel, Oren S. Rosenberg, Kliment A Verba, David A. Agard, Melanie Ott, Michael Emerman, Natalia Jura, Mark von Zastrow, Eric Verdin, Alan Ashworth, Olivier Schwartz, Christophe d’Enfert, Shaeri Mukherjee, Matt Jacobson, Harmit S. Malik, Danica G. Fujimori, Trey Ideker, Charles S. Craik, Stephen N. Floor, James S. Fraser, John D. Gross, Andrej Sali, Bryan L. Roth, Davide Ruggero, Jack Taunton, Tanja Kortemme, Pedro Beltrao, Marco Vignuzzi, Adolfo García-Sastre, Kevan M. Shokat, Brian K. Shoichet, Nevan J. Krogan

Nature. Author manuscript; available in PMC 2020 Oct 30.

Published in final edited form as: Nature. 2020 Jul; 583(7816): 459–468. Published online 2020 Apr 30. doi: 10.1038/s41586-020-2286-9

PMCID:: PMC7431030

Article PDF–7.7M

Select item 349180316.

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N Ananthakrishnan, Vibeke Andersen, Jane M Andrews, Leonard Baidoo, Tobias Balschun, Peter A Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C Lawrance, Charlie W Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y Ponsioen, Uros Potocnik, Natalie J Prescott, Miguel Regueiro, Jerome I Rotter, Richard K Russell, Jeremy D Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A Simms, Jurgita Sventoraityte, Stephan R Targan, Kent D Taylor, Mark Tremelling, Hein W Verspaget, Martine De Vos, Cisca Wijmenga, David C Wilson, Juliane Winkelmann, Ramnik J Xavier, Sebastian Zeissig, Bin Zhang, Clarence K Zhang, Hongyu Zhao, The International IBD Genetics Consortium, Mark S Silverberg, Vito Annese, Hakon Hakonarson, Steven R Brant, Graham Radford-Smith, Christopher G Mathew, John D Rioux, Eric E Schadt, Mark J Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C Barrett, Judy H Cho

Nature. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Nature. 2012 Nov 1; 491(7422): 119–124. doi: 10.1038/nature11582

PMCID:: PMC3491803

Article PDF–706K

Select item 412394417.

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover

David J. Elzi, Meihua Song, Kevin Hakala, Susan T. Weintraub, Yuzuru Shiio

J Proteome Res. 2014 Aug 1; 13(8): 3783–3791. Published online 2014 Jul 7. doi: 10.1021/pr500387m

PMCID:: PMC4123944

Article PDF–3.8M

Select item 876907218.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Article PDF–2.9M

Select item 484876219.

Pooled‐matrix protein interaction screens using Barcode Fusion Genetics

Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth

Mol Syst Biol. 2016 Apr; 12(4): 863. Published online 2016 Apr 23. doi: 10.15252/msb.20156660

PMCID:: PMC4848762

Article PDF–2.8M

Select item 729072120.

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation

Danielle G. May, Kelsey L. Scott, Alexandre R. Campos, Kyle J. Roux

Cells. 2020 May; 9(5): 1070. Published online 2020 Apr 25. doi: 10.3390/cells9051070

PMCID:: PMC7290721

Article PDF–9.2M

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