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Select item 99846421.

P2Y12 receptor gene polymorphisms are associated with epilepsy

Qi Wang, Nan-Rui Shi, Peng Lv, Juan Liu, Ji-Zhou Zhang, Bin-Lu Deng, Yan-Qin Zuo, Jie Yang, Xin Wang, Xiang Chen, Xiu-Min Hu, Ting-Ting Liu, Jie Liu

Purinergic Signal. 2023 Mar; 19(1): 155–162. Published online 2022 Feb 17. doi: 10.1007/s11302-022-09848-4

PMCID:: PMC9984642

Abstract Article PDF–546K

Select item 98938392.

Correlation P2Y12 Genetic Polymorphism As Risk Factor of Clopidogrel Resistance in Indonesian Stroke Patients

Rakhmad Hidayat, Al Rasyid, Salim Harris, Alida Harahap, Herqutanto, Melva Louisa, Erlin Listiyaningsih, Aldy Safruddin Rambe, Tonny Loho

Vasc Health Risk Manag. 2023; 19: 53–61. Published online 2023 Jan 29. doi: 10.2147/VHRM.S386107

PMCID:: PMC9893839

Abstract Article PDF–1.2M

Select item 98016273.

Influence of genetic polymorphisms in P2Y12 receptor signaling pathway on antiplatelet response to clopidogrel in coronary heart disease

Yan-Jiao Zhang, Dong-Jie Li, Zhong-Yi Li, Xiao-Lei Hu, He Li, Qi-Lin Ma, Xiao-Ping Chen

BMC Cardiovasc Disord. 2022; 22: 575. Published online 2022 Dec 30. doi: 10.1186/s12872-022-02988-w

PMCID:: PMC9801627

Abstract Article PDF–1.4M

Select item 94495904.

Inhibiting P2Y12 receptor relieves LPS‐induced inflammation and endothelial dysfunction

Xiuxia Han

Immun Inflamm Dis. 2022 Oct; 10(10): e697. Published online 2022 Sep 7. doi: 10.1002/iid3.697

PMCID:: PMC9449590

Abstract Article PDF–2.0M

Select item 82341745.

The Molecular Aspects of Disturbed Platelet Activation through ADP/P2Y₁₂ Pathway in Multiple Sclerosis

Angela Dziedzic, Elzbieta Miller, Joanna Saluk-Bijak, Marta Niwald, Michal Bijak

Int J Mol Sci. 2021 Jun; 22(12): 6572. Published online 2021 Jun 18. doi: 10.3390/ijms22126572

PMCID:: PMC8234174

Abstract Article PDF–3.4M

Select item 79159796.

Microglia and Neuroinflammation: What Place for P2RY12?

Albert Gómez Morillas, Valérie C. Besson, Dominique Lerouet

Int J Mol Sci. 2021 Feb; 22(4): 1636. Published online 2021 Feb 6. doi: 10.3390/ijms22041636

PMCID:: PMC7915979

Abstract Article PDF–1001K

Select item 70858257.

Association between P2RY12 Gene Polymorphisms and IVIG Resistance in Kawasaki Patients

Zhouping Wang, Yufen Xu, Huazhong Zhou, Yanfei Wang, Wei Li, Zhaoliang Lu, Zhiyong Jiang, Xueping Gu, Hao Zheng, Lanlan Zeng, Ping Huang, Li Zhang, Xiaoqiong Gu

Cardiovasc Ther. 2020; 2020: 3568608. Published online 2020 Mar 10. doi: 10.1155/2020/3568608

PMCID:: PMC7085825

Abstract Article PDF–482K

Select item 70142488.

Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer’s Disease Brains

Douglas G. Walker, Tiffany M. Tang, Anarmaa Mendsaikhan, Ikuo Tooyama, Geidy E. Serrano, Lucia I. Sue, Thomas G. Beach, Lih-Fen Lue

Int J Mol Sci. 2020 Jan; 21(2): 678. Published online 2020 Jan 20. doi: 10.3390/ijms21020678

PMCID:: PMC7014248

Abstract Article PDF–6.7M

Select item 67798949.

ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12

Loreen Kloss, Claudia Dollt, Kai Schledzewski, Andreas Krewer, Susanne Melchers, Calin Manta, Carsten Sticht, Carolina de la Torre, Jochen Utikal, Viktor Umansky, Astrid Schmieder

Cell Death Dis. 2019 Oct; 10(10): 760. Published online 2019 Oct 7. doi: 10.1038/s41419-019-2010-6

PMCID:: PMC6779894

Abstract Article PDF–3.2M

Select item 509909310.

Inherited dysfunctional platelet P2Y₁₂ receptor mutations associated with bleeding disorders

Anna Lecchi, Eti A. Femia, Silvia Paoletta, Arnaud Dupuis, Philippe Ohlmann, Christian Gachet, Kenneth A. Jacobson, Katharina Machura, Gian M. Podda, Barbara Zieger, Marco Cattaneo

Hamostaseologie. Author manuscript; available in PMC 2017 Nov 7.

Published in final edited form as: Hamostaseologie. 2016 Nov 7; 36(4): 279–283. Published online 2016 Aug 4. doi: 10.5482/HAMO-16-03-0010

PMCID:: PMC5099093

Abstract Article PDF–881K

Select item 475703111.

The Ratio of ADP- to TRAP-Induced Platelet Aggregation Quantifies P2Y₁₂-Dependent Platelet Inhibition Independently of the Platelet Count

Christoph B. Olivier, Melanie Meyer, Hans Bauer, Katharina Schnabel, Patrick Weik, Qian Zhou, Christoph Bode, Martin Moser, Philipp Diehl

PLoS One. 2016; 11(2): e0149053. Published online 2016 Feb 17. doi: 10.1371/journal.pone.0149053

PMCID:: PMC4757031

Abstract Article PDF–230K

Select item 457801612.

A pharmacodynamic study of the optimal P2Y₁₂ inhibitor regimen for East Asian patients with acute coronary syndrome

Ji Hyun Lee, Sung Gyun Ahn, Bonil Park, Sang Wook Park, Yong Seok Kang, Jun-Won Lee, Young Jin Youn, Min-Soo Ahn, Jang-Young Kim, Byung-Su Yoo, Seung-Hwan Lee, Junghan Yoon

Korean J Intern Med. 2015 Sep; 30(5): 620–628. Published online 2015 Aug 27. doi: 10.3904/kjim.2015.30.5.620

PMCID:: PMC4578016

Abstract Article PDF–404K

Select item 456500113.

Aspirin and P2Y₁₂ inhibition attenuate platelet-induced ovarian cancer cell invasion

Niamh M. Cooke, Cathy D. Spillane, Orla Sheils, John O’Leary, Dermot Kenny

BMC Cancer. 2015; 15: 627. Published online 2015 Sep 9. doi: 10.1186/s12885-015-1634-x

PMCID:: PMC4565001

Abstract Article PDF–930K

Select item 431923114.

Identification of a new dysfunctional platelet P2Y₁₂ receptor variant associated with bleeding diathesis

Anna Lecchi, Cristina Razzari, Silvia Paoletta, Arnaud Dupuis, Lea Nakamura, Philippe Ohlmann, Christian Gachet, Kenneth A. Jacobson, Barbara Zieger, Marco Cattaneo

Blood. 2015 Feb 5; 125(6): 1006–1013. Prepublished online 2014 Nov 26. doi: 10.1182/blood-2013-07-517896

PMCID:: PMC4319231

Abstract Article

Select item 420382715.

Another “String to the Bow” of PJ34, a Potent Poly(ADP-Ribose)Polymerase Inhibitor: An Antiplatelet Effect through P2Y₁₂ Antagonism?

Marie Lechaftois, Elise Dreano, Bruno Palmier, Isabelle Margaill, Catherine Marchand-Leroux, Christilla Bachelot-Loza, Dominique Lerouet

PLoS One. 2014; 9(10): e110776. Published online 2014 Oct 20. doi: 10.1371/journal.pone.0110776

PMCID:: PMC4203827

Abstract Article PDF–868K

Select item 417430716.

Structure of the human P2Y₁₂ receptor in complex with an antithrombotic drug

Kaihua Zhang, Jin Zhang, Zhan-Guo Gao, Dandan Zhang, Lan Zhu, Gye Won Han, Steven M. Moss, Silvia Paoletta, Evgeny Kiselev, Weizhen Lu, Gustavo Fenalti, Wenru Zhang, Christa E. Müller, Huaiyu Yang, Hualiang Jiang, Vadim Cherezov, Vsevolod Katritch, Kenneth A. Jacobson, Raymond C. Stevens, Beili Wu, Qiang Zhao

Nature. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: Nature. 2014 May 1; 509(7498): 115–118. Published online 2014 Mar 23. doi: 10.1038/nature13083

PMCID:: PMC4174307

Abstract Article PDF–2.5M

Select item 416335117.

Glycoprotein IIb/IIIa and P2Y₁₂ Induction by Oligochitosan Accelerates Platelet Aggregation

Mercy Halleluyah Periayah, Ahmad Sukari Halim, Nik Soriani Yaacob, Arman Zaharil Mat Saad, Abdul Rahim Hussein, Ahmad Hazri Abdul Rashid, Zanariah Ujang

Biomed Res Int. 2014; 2014: 653149. Published online 2014 Aug 28. doi: 10.1155/2014/653149

PMCID:: PMC4163351

Abstract Article PDF–1.0M

Select item 412891718.

Agonist-bound structure of the human P2Y₁₂ receptor

Jin Zhang, Kaihua Zhang, Zhan-Guo Gao, Silvia Paoletta, Dandan Zhang, Gye Won Han, Tingting Li, Limin Ma, Wenru Zhang, Christa E. Müller, Huaiyu Yang, Hualiang Jiang, Vadim Cherezov, Vsevolod Katritch, Kenneth A. Jacobson, Raymond C. Stevens, Beili Wu, Qiang Zhao

Nature. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Nature. 2014 May 1; 509(7498): 119–122. doi: 10.1038/nature13288

PMCID:: PMC4128917

Abstract Article PDF–2.1M

Select item 397693119.

Association of P2Y12 Gene Promoter DNA Methylation with the Risk of Clopidogrel Resistance in Coronary Artery Disease Patients

Jia Su, Xiaojing Li, Qinglin Yu, Yahui Liu, Yaqing Wang, Haojun Song, Hanbin Cui, Weiping Du, Xiaohong Fei, Junsong Liu, Shaoyi Lin, Jian Wang, Wenyuan Zheng, Jinyan Zhong, Lulu Zhang, Maoqing Tong, Jin Xu, Xiaomin Chen

Biomed Res Int. 2014; 2014: 450814. Published online 2014 Mar 18. doi: 10.1155/2014/450814

PMCID:: PMC3976931

Abstract Article PDF–852K

Select item 369965720.

Comparison of a New P2Y12 Receptor Specific Platelet Aggregation Test with Other Laboratory Methods in Stroke Patients on Clopidogrel Monotherapy

Zsuzsa Bagoly, Ferenc Sarkady, Tünde Magyar, János Kappelmayer, Endre Pongrácz, László Csiba, László Muszbek

PLoS One. 2013; 8(7): e69417. Published online 2013 Jul 2. doi: 10.1371/journal.pone.0069417

PMCID:: PMC3699657

Abstract Article PDF–1.5M

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