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Select item 111583701.

Expression of CUB domain containing protein (CDCP1) is correlated with prognosis and survival of patients with adenocarcinoma of lung

Jun‐ichiro Ikeda, Tomofumi Oda, Masayoshi Inoue, Takamasa Uekita, Ryuichi Sakai, Meinoshin Okumura, Katsuyuki Aozasa, Eiichi Morii

Cancer Sci. 2009 Mar; 100(3): 429–433. Published online 2008 Dec 11. doi: 10.1111/j.1349-7006.2008.01066.x

PMCID:: PMC11158370

Abstract Article PDF–171K

Select item 99897452.

Metastatic prostate cancer‐derived extracellular vesicles facilitate osteoclastogenesis by transferring the CDCP1 protein

Fumihiko Urabe, Nobuyoshi Kosaka, Yusuke Yamamoto, Kagenori Ito, Kurataka Otsuka, Carolina Soekmadji, Shin Egawa, Takahiro Kimura, Takahiro Ochiya

J Extracell Vesicles. 2023 Mar; 12(3): 12312. Published online 2023 Mar 7. doi: 10.1002/jev2.12312

PMCID:: PMC9989745

Abstract Article PDF–2.3M

Select item 99807593.

CDCP1 (CUB domain containing protein 1) is a potential urine-based biomarker in the diagnosis of low-grade urothelial carcinoma

Chien-Liang Liu, Hung-Wen Tsai, Shu-Ling Peng, Ching-Ping Chang, Yu-Hao Chang, Huei-Sheng Huang

PLoS One. 2023; 18(3): e0281873. Published online 2023 Mar 2. doi: 10.1371/journal.pone.0281873

PMCID:: PMC9980759

Abstract Article PDF–2.0M

Select item 88437434.

Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers

Shion A. Lim, Jie Zhou, Alexander J. Martinko, Yung-Hua Wang, Ekaterina V. Filippova, Veronica Steri, Donghui Wang, Soumya G. Remesh, Jia Liu, Byron Hann, Anthony A. Kossiakoff, Michael J. Evans, Kevin K. Leung, James A. Wells

J Clin Invest. 2022 Feb 15; 132(4): e154604. Published online 2022 Feb 15. doi: 10.1172/JCI154604

PMCID:: PMC8843743

Abstract Article PDF–2.4M

Select item 84552025.

Preclinical Molecular PET-CT Imaging Targeting CDCP1 in Colorectal Cancer

Tahleesa J. Cuda, Yaowu He, Thomas Kryza, Tashbib Khan, Brian W. Tse, Kamil A. Sokolowski, Cheng Liu, Nicholas Lyons, Madeline Gough, Cameron E. Snell, David K. Wyld, Stephen Rose, Andrew D. Riddell, Andrew R. L. Stevenson, Paul A. Thomas, David A. Clark, Simon Puttick, John D. Hooper

Contrast Media Mol Imaging. 2021; 2021: 3153278. Published online 2021 Sep 13. doi: 10.1155/2021/3153278

PMCID:: PMC8455202

Abstract Article PDF–3.6M

Select item 76571676.

Suppression of autophagy by CUB domain‐containing protein 1 signaling is essential for anchorage‐independent survival of lung cancer cells

Takamasa Uekita, Satoko Fujii, Yuri Miyazawa, Akinori Hashiguchi, Hitosi Abe, Michiie Sakamoto, Ryuichi Sakai

Cancer Sci. 2013 Jul; 104(7): 865–870. Published online 2013 Apr 19. doi: 10.1111/cas.12154

PMCID:: PMC7657167

Abstract Article PDF–641K

Select item 76112357.

Prospective identification of elevated circulating CDCP1 in patients years before onset of lung cancer

Sonia Dagnino, Barbara Bodinier, Florence Guida, Karl Smith-Byrne, Dusan Petrovic, Matthew D. Whitaker, Therese Haugdahl Nøst, Claudia Agnoli, Domenico Palli, Carlotta Sacerdote, Salvatore Panico, Rosario Tumino, Matthias B. Schulze, Mikael Johansson, Pekka Keski-Rahkonen, Augustin Scalbert, Paolo Vineis, Mattias Johansson, Torkjel M. Sandanger, Roel C.H. Vermeulen, Marc Chadeau-Hyam

Cancer Res. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Cancer Res. 2021 Jul 1; 81(13): 3738–3748. Published online 2021 Feb 11. doi: 10.1158/0008-5472.CAN-20-3454

PMCID:: PMC7611235

Abstract Article PDF–2.2M

Select item 70863618.

Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma

Thomas Kryza, Tashbib Khan, Simon Puttick, Chao Li, Kamil A Sokolowski, Brian WC Tse, Tahleesa Cuda, Nicholas Lyons, Madeline Gough, Julia Yin, Ashleigh Parkin, Elena I Deryugina, James P. Quigley, Ruby H. P. Law, James C. Whisstock, Andrew D. Riddell, Andrew P. Barbour, David K. Wyld, Paul A. Thomas, Stephen Rose, Cameron E. Snell, Marina Pajic, Yaowu He, John D. Hooper

Theranostics. 2020; 10(9): 4116–4133. Published online 2020 Mar 4. doi: 10.7150/thno.43589

PMCID:: PMC7086361

Abstract Article PDF–3.3M

Select item 70601689.

Identification of CD318 (CDCP1) as novel prognostic marker in AML

Jonas S. Heitmann, Ilona Hagelstein, Clemens Hinterleitner, Malte Roerden, Gundram Jung, Helmut R. Salih, Melanie Märklin, Joseph Kauer

Ann Hematol. 2020; 99(3): 477–486. Published online 2020 Jan 21. doi: 10.1007/s00277-020-03907-9

PMCID:: PMC7060168

Abstract Article PDF–1002K

Select item 596704110.

The PDGFRβ/ERK1/2 pathway regulates CDCP1 expression in triple-negative breast cancer

Luca Forte, Federica Turdo, Cristina Ghirelli, Piera Aiello, Patrizia Casalini, Marilena Valeria Iorio, Elvira D’Ippolito, Patrizia Gasparini, Roberto Agresti, Beatrice Belmonte, Gabriella Sozzi, Lucia Sfondrini, Elda Tagliabue, Manuela Campiglio, Francesca Bianchi

BMC Cancer. 2018; 18: 586. Published online 2018 May 23. doi: 10.1186/s12885-018-4500-9

PMCID:: PMC5967041

Abstract Article PDF–5.8M

Select item 555902011.

CDCP1 drives triple-negative breast cancer metastasis through reduction of lipid-droplet abundance and stimulation of fatty acid oxidation

Heather J. Wright, Jue Hou, Binzhi Xu, Marvin Cortez, Eric O. Potma, Bruce J. Tromberg, Olga V. Razorenova

Proc Natl Acad Sci U S A. 2017 Aug 8; 114(32): E6556–E6565. Published online 2017 Jul 24. doi: 10.1073/pnas.1703791114

PMCID:: PMC5559020

Abstract Article PDF–1.9M

Select item 534250512.

CDCP1 is a novel marker of the most aggressive human triple-negative breast cancers

Federica Turdo, Francesca Bianchi, Patrizia Gasparini, Marco Sandri, Marianna Sasso, Loris De Cecco, Luca Forte, Patrizia Casalini, Piera Aiello, Lucia Sfondrini, Roberto Agresti, Maria Luisa Carcangiu, Ilaria Plantamura, Gabriella Sozzi, Elda Tagliabue, Manuela Campiglio

Oncotarget. 2016 Oct 25; 7(43): 69649–69665. Published online 2016 Sep 10. doi: 10.18632/oncotarget.11935

PMCID:: PMC5342505

Abstract Article PDF–9.1M

Select item 498550513.

CDCP1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer

HJ Wright, J Arulmoli, M Motazedi, LJ Nelson, FS Heinemann, LA Flanagan, OV Razorenova

Oncogene. Author manuscript; available in PMC 2016 Sep 8.

Published in final edited form as: Oncogene. 2016 Sep 8; 35(36): 4762–4772. Published online 2016 Feb 15. doi: 10.1038/onc.2016.7

PMCID:: PMC4985505

Abstract Article PDF–3.1M

Select item 497593414.

The role of membrane microdomains in transmembrane signaling through the epithelial glycoprotein Gp140/CDCP1

Stacy M. Alvares, Clarence A. Dunn, Tod A. Brown, Elizabeth E. Wayner, William G. Carter

Biochim Biophys Acta. Author manuscript; available in PMC 2016 Aug 6.

Published in final edited form as: Biochim Biophys Acta. 2008 Mar; 1780(3): 486–496. Published online 2008 Jan 26. doi: 10.1016/j.bbagen.2008.01.010

PMCID:: PMC4975934

Abstract Article PDF–927K

Select item 481577315.

Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer

Brittney S Harrington, Yaowu He, Claire M Davies, Sarah J Wallace, Mark N Adams, Elizabeth A Beaven, Deborah K Roche, Catherine Kennedy, Naven P Chetty, Alexander J Crandon, Christopher Flatley, Niara B Oliveira, Catherine M Shannon, Anna deFazio, Anna V Tinker, C Blake Gilks, Brian Gabrielli, Donal J Brennan, Jermaine I Coward, Jane E Armes, Lewis C Perrin, John D Hooper

Br J Cancer. 2016 Feb 16; 114(4): 417–426. Published online 2016 Feb 4. doi: 10.1038/bjc.2015.471