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Select item 106855631.

SIX1 amplification modulates stemness and tumorigenesis in breast cancer

Liantao Guo, Faminzi Li, Hanqing Liu, Deguang Kong, Chuang Chen, Shengrong Sun

J Transl Med. 2023; 21: 866. Published online 2023 Nov 29. doi: 10.1186/s12967-023-04679-2

PMCID:: PMC10685563

Article PDF–5.8M

Select item 103619702.

Phenotypic and molecular basis of SIX1 variants linked to non-syndromic deafness and atypical branchio-otic syndrome in South Korea

Somin Lee, Yejin Yun, Ju Hyuen Cha, Jin Hee Han, Dae Hee Lee, Jae-Jin Song, Moo Kyun Park, Jun Ho Lee, Seung Ha Oh, Byung Yoon Choi, Sang-Yeon Lee

Sci Rep. 2023; 13: 11776. Published online 2023 Jul 21. doi: 10.1038/s41598-023-38909-w

PMCID:: PMC10361970

Article PDF–2.6M

Select item 86331733.

Homeoprotein SIX1 compromises antitumor immunity through TGF-β-mediated regulation of collagens

Wancheng Liu, Meiling Gao, Lili Li, Yu Chen, Huimin Fan, Qiaomei Cai, Yueyue Shi, Chaohu Pan, Junxiao Liu, Lucy S. Cheng, Heng Yang, Genhong Cheng

Cell Mol Immunol. 2021 Dec; 18(12): 2660–2672. Published online 2021 Nov 15. doi: 10.1038/s41423-021-00800-x

PMCID:: PMC8633173

Article PDF–4.1M

Select item 74499274.

O-GlcNAcylation of SIX1 enhances its stability and promotes Hepatocellular Carcinoma Proliferation

Yi Chu, Mingzuo Jiang, Nan Wu, Bing Xu, Wenjiao Li, Haiming Liu, Song Su, Yanting Shi, Hao Liu, Xiaoliang Gao, Xin Fu, Di Chen, Xiaowei Li, Weijie Wang, Jie Liang, Yongzhan Nie, Daiming Fan

Theranostics. 2020; 10(21): 9830–9842. Published online 2020 Aug 2. doi: 10.7150/thno.45161

PMCID:: PMC7449927

Article PDF–2.1M

Select item 72058235.

Increased SIX‐1 expression promotes breast cancer metastasis by regulating lncATB‐miR‐200s‐ZEB1 axis

Lizhe Zhu, Siyuan Jiang, Shibo Yu, Xiaoxu Liu, Shengyu Pu, Peiling Xie, Heyan Chen, Xiaoqin Liao, Ke Wang, Bin Wang

J Cell Mol Med. 2020 May; 24(9): 5290–5303. Published online 2020 Mar 30. doi: 10.1111/jcmm.15185

PMCID:: PMC7205823

Article PDF–2.8M

Select item 66098586.

Six1 regulates leukemia stem cell maintenance in acute myeloid leukemia

Yajing Chu, Yangpeng Chen, Mengke Li, Deyang Shi, Bichen Wang, Yu Lian, Xuelian Cheng, Xiaomin Wang, Mingjiang Xu, Tao Cheng, Jun Shi, Weiping Yuan

Cancer Sci. 2019 Jul; 110(7): 2200–2210. Published online 2019 May 29. doi: 10.1111/cas.14033

PMCID:: PMC6609858

Article PDF–1.4M

Select item 63616097.

Sine oculis homeobox 1 promotes proliferation and migration of human colorectal cancer cells through activation of Wnt/β‐catenin signaling

Wenxin Song, Jian Ma, Bingbing Lei, Xin Yuan, Binfeng Cheng, Haijie Yang, Mian Wang, Zhiwei Feng, Lei Wang

Cancer Sci. 2019 Feb; 110(2): 608–616. Published online 2019 Jan 28. doi: 10.1111/cas.13905

PMCID:: PMC6361609

Article PDF–1.0M

Select item 59160928.

The Sineoculis Homeobox Homolog 1 (SIX1) Gene Regulates Paclitaxel Resistance by Affecting Reactive Oxygen Species and Autophagy in Human Hepatocellular Carcinoma Cell Line HepG2

Baowei Li, Shahe Zhao, Ruipeng Geng, Zhongchao Huo, Hui Zhang

Med Sci Monit. 2018; 24: 2271–2279. Published online 2018 Apr 15. doi: 10.12659/MSM.906361

PMCID:: PMC5916092

Article PDF–1.1M

Select item 53839579.

Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer

Tristan Lerbs, Savita Bisht, Sebastian Schölch, Mathieu Pecqueux, Glen Kristiansen, Martin Schneider, Bianca T. Hofmann, Thilo Welsch, Christoph Reissfelder, Nuh N. Rahbari, Johannes Fritzmann, Peter Brossart, Jürgen Weitz, Georg Feldmann, Christoph Kahlert

BMC Cancer. 2017; 17: 249. Published online 2017 Apr 7. doi: 10.1186/s12885-017-3225-5

PMCID:: PMC5383957

Article PDF–1.3M

Select item 476593610.

The role of Six1 signaling in paclitaxel-dependent apoptosis in MCF-7 cell line

Marzieh Armat, Taiebeh Oghabi Bakhshaiesh, Mehdi Sabzichi, Dariush Shanehbandi, Simin Sharifi, Ommoleila Molavi, Jamal Mohammadian, Mohammad Saeid Hejazi, Nasser Samadi

Bosn J Basic Med Sci. 2016 Feb; 16(1): 28–34. doi: 10.17305/bjbms.2016.674

PMCID:: PMC4765936

Article PDF–2.5M

Select item 474188311.

Aberrant expression of homeobox gene SIX1 in Hodgkin lymphoma

Stefan Nagel, Corinna Meyer, Maren Kaufmann, Hans G. Drexler, Roderick A.F. MacLeod

Oncotarget. 2015 Nov 24; 6(37): 40112–40126. Published online 2015 Oct 12. doi: 10.18632/oncotarget.5556

PMCID:: PMC4741883

Article PDF–1.8M

Select item 425985812.

Six1 Overexpression at Early Stages of HPV16-mediated Transformation of Human Keratinocytes Promotes Differentiation Resistance and EMT

Hanwen Xu, Lucia Pirisi, Kim E. Creek

Virology. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Virology. 2015 Jan 1; 474: 144–153. Published online 2014 Nov 17. doi: 10.1016/j.virol.2014.10.010

PMCID:: PMC4259858

Article PDF–3.1M

Select item 409729413.

Overexpression of sineoculis homeobox homolog 1 predicts poor prognosis of hepatocellular carcinoma

Jienan Kong, Xianchun Zhou, Shusen Liu, Tiefeng Jin, Yingshi Piao, Chao Liu, Zhenhua Lin

Int J Clin Exp Pathol. 2014; 7(6): 3018–3027. Published online 2014 May 15.

PMCID:: PMC4097294

Article PDF–1.2M

Select item 404324014.

Six1 promotes epithelial–mesenchymal transition and malignant conversion in human papillomavirus type 16-immortalized human keratinocytes

Hanwen Xu, Yu Zhang, Diego Altomare, Maria M. Peña, Fang Wan, Lucia Pirisi, Kim E. Creek

Carcinogenesis. 2014 Jun; 35(6): 1379–1388. Published online 2014 Feb 26. doi: 10.1093/carcin/bgu050

PMCID:: PMC4043240

Article PDF–7.2M

Select item 392590715.

Targeting Six1 by lentivirus-mediated RNA interference inhibits colorectal cancer cell growth and invasion

Zhaoming Li, Tian Tian, Xiaopeng Hu, Xudong Zhang, Lifeng Li, Feifei Nan, Yu Chang, Xinhua Wang, Zhenchang Sun, Feng Lv, Mingzhi Zhang

Int J Clin Exp Pathol. 2014; 7(2): 631–639. Published online 2014 Jan 15.

PMCID:: PMC3925907

Article PDF–790K

Select item 368093616.

Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways

Ritsuko Iwanaga, Chu-An Wang, Douglas S Micalizzi, J Chuck Harrell, Paul Jedlicka, Carol A Sartorius, Peter Kabos, Susan M Farabaugh, Andrew P Bradford, Heide L Ford

Breast Cancer Res. 2012; 14(4): R100. Published online 2012 Jul 5. doi: 10.1186/bcr3219

PMCID:: PMC3680936

Article PDF–3.7M

Select item 360410217.

Six1 Promotes Proliferation of Pancreatic Cancer Cells via Upregulation of Cyclin D1 Expression

Zhaoming Li, Tian Tian, Feng Lv, Yu Chang, Xinhua Wang, Lei Zhang, Xin Li, Ling Li, Wang Ma, Jingjing Wu, Mingzhi Zhang

PLoS One. 2013; 8(3): e59203. Published online 2013 Mar 20. doi: 10.1371/journal.pone.0059203

PMCID:: PMC3604102

Article PDF–1.2M

Select item 273591418.

The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-β signaling

Douglas S. Micalizzi, Kimberly L. Christensen, Paul Jedlicka, Ricardo D. Coletta, Anna E. Barón, J. Chuck Harrell, Kathryn B. Horwitz, Dean Billheimer, Karen A. Heichman, Alana L. Welm, William P. Schiemann, Heide L. Ford

J Clin Invest. 2009 Sep 1; 119(9): 2678–2690. Published online 2009 Aug 24. doi: 10.1172/JCI37815

PMCID:: PMC2735914

Article PDF–4.1M

Select item 273590919.

Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition

Erica L. McCoy, Ritsuko Iwanaga, Paul Jedlicka, Nee-Shamo Abbey, Lewis A. Chodosh, Karen A. Heichman, Alana L. Welm, Heide L. Ford

J Clin Invest. 2009 Sep 1; 119(9): 2663–2677. Published online 2009 Aug 24. doi: 10.1172/JCI37691

PMCID:: PMC2735909

Article PDF–5.1M

Select item 173553420.

A gene locus for branchio-otic syndrome maps to chromosome 14q21.3-q24.3

R Ruf, J Berkman, M Wolf, P Nurnberg, M Gattas, E Ruf, V Hyland, J Kromberg, I Glass, J Macmillan, E Otto, G Nurnberg, B Lucke, H Hennies, F Hildebrandt

J Med Genet. 2003 Jul; 40(7): 515–519. doi: 10.1136/jmg.40.7.515