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Select item 105335291.

MRPS6 modulates glucose-stimulated insulin secretion in mouse islet cells through mitochondrial unfolded protein response

Danhong Lin, Jingwen Yu, Leweihua Lin, Qianying Ou, Huibiao Quan

Sci Rep. 2023; 13: 16173. Published online 2023 Sep 27. doi: 10.1038/s41598-023-43438-7

PMCID:: PMC10533529

Abstract Article PDF–6.9M

Select item 26810112.

Genome-wide association of early-onset myocardial infarction with common single nucleotide polymorphisms, common copy number variants, and rare copy number variants

Myocardial Infarction Genetics Consortium

Nat Genet. Author manuscript; available in PMC 2009 Sep 1.

Published in final edited form as: Nat Genet. 2009 Mar; 41(3): 334–341. Published online 2009 Feb 8. doi: 10.1038/ng.327

Correction in:: volume 41 on page 762

PMCID:: PMC2681011

Article PDF–630K

Select item 29653513.

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

Samuli Ripatti, Emmi Tikkanen, Marju Orho-Melander, Aki S Havulinna, Kaisa Silander, Amitabh Sharma, Candace Guiducci, Markus Perola, Antti Jula, Juha Sinisalo, Marja-Liisa Lokki, Markku S Nieminen, Olle Melander, Veikko Salomaa, Leena Peltonen, Sekar Kathiresan

Lancet. 2010 Oct 23; 376(9750): 1393–1400. doi: 10.1016/S0140-6736(10)61267-6

PMCID:: PMC2965351

Abstract Article

Select item 33517294.

Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses

Nicolas Simonis, Jean-François Rual, Irma Lemmens, Mathieu Boxus, Tomoko Hirozane-Kishikawa, Jean-Stéphane Gatot, Amélie Dricot, Tong Hao, Didier Vertommen, Sébastien Legros, Sarah Daakour, Niels Klitgord, Maud Martin, Jean-François Willaert, Franck Dequiedt, Vincent Navratil, Michael E Cusick, Arsène Burny, Carine Van Lint, David E Hill, Jan Tavernier, Richard Kettmann, Marc Vidal, Jean-Claude Twizere

Retrovirology. 2012; 9: 26. Published online 2012 Mar 29. doi: 10.1186/1742-4690-9-26

PMCID:: PMC3351729

Abstract Article PDF–1.3M

Select item 31192615.

Large-scale association analyses identifies 13 new susceptibility loci for coronary artery disease

Heribert Schunkert, Inke R. König, Sekar Kathiresan, Muredach P. Reilly, Themistocles L. Assimes, Hilma Holm, Michael Preuss, Alexandre F. R. Stewart, Maja Barbalic, Christian Gieger, Devin Absher, Zouhair Aherrahrou, Hooman Allayee, David Altshuler, Sonia S. Anand, Karl Andersen, Jeffrey L. Anderson, Diego Ardissino, Stephen G. Ball, Anthony J. Balmforth, Timothy A. Barnes, Diane M. Becker, Lewis C. Becker, Klaus Berger, Joshua C. Bis, S. Matthijs Boekholdt, Eric Boerwinkle, Peter S. Braund, Morris J. Brown, Mary Susan Burnett, Ian Buysschaert, Cardiogenics, John F. Carlquist, Li Chen, Sven Cichon, Veryan Codd, Robert W. Davies, George Dedoussis, Abbas Dehghan, Serkalem Demissie, Joseph M. Devaney, Ron Do, Angela Doering, Sandra Eifert, Nour Eddine El Mokhtari, Stephen G. Ellis, Roberto Elosua, James C. Engert, Stephen E. Epstein, Ulf de Faire, Marcus Fischer, Aaron R. Folsom, Jennifer Freyer, Bruna Gigante, Domenico Girelli, Solveig Gretarsdottir, Vilmundur Gudnason, Jeffrey R. Gulcher, Eran Halperin, Naomi Hammond, Stanley L. Hazen, Albert Hofman, Benjamin D. Horne, Thomas Illig, Carlos Iribarren, Gregory T. Jones, J.Wouter Jukema, Michael A. Kaiser, Lee M. Kaplan, John J.P. Kastelein, Kay-Tee Khaw, Joshua W. Knowles, Genovefa Kolovou, Augustine Kong, Reijo Laaksonen, Diether Lambrechts, Karin Leander, Guillaume Lettre, Mingyao Li, Wolfgang Lieb, Patrick Linsel-Nitschke, Christina Loley, Andrew J. Lotery, Pier M. Mannucci, Seraya Maouche, Nicola Martinelli, Pascal P. McKeown, Christa Meisinger, Thomas Meitinger, Olle Melander, Pier Angelica Merlini, Vincent Mooser, Thomas Morgan, Thomas W. Mühleisen, Joseph B. Muhlestein, Thomas Münzel, Kiran Musunuru, Janja Nahrstaedt, Christopher P. Nelson, Markus M. Nöthen, Oliviero Olivieri, Riyaz S. Patel, Chris C. Patterson, Annette Peters, Flora Peyvandi, Liming Qu, Arshed A. Quyyumi, Daniel J. Rader, Loukianos S. Rallidis, Catherine Rice, Frits R. Rosendaal, Diana Rubin, Veikko Salomaa, M. Lourdes Sampietro, Manj S. Sandhu, Eric Schadt, Arne Schäfer, Arne Schillert, Stefan Schreiber, Jürgen Schrezenmeir, Stephen M. Schwartz, David S. Siscovick, Mohan Sivananthan, Suthesh Sivapalaratnam, Albert Smith, Tamara B. Smith, Jaapjan D. Snoep, Nicole Soranzo, John A. Spertus, Klaus Stark, Kathy Stirrups, Monika Stoll, W. H. Wilson Tang, Stephanie Tennstedt, Gudmundur Thorgeirsson, Gudmar Thorleifsson, Maciej Tomaszewski, Andre G. Uitterlinden, Andre M. van Rij, Benjamin F. Voight, Nick J. Wareham, George A. Wells, H.-Erich Wichmann, Philipp S. Wild, Christina Willenborg, Jaqueline C. M. Witteman, Benjamin J. Wright, Shu Ye, Tanja Zeller, Andreas Ziegler, Francois Cambien, Alison H. Goodall, L. Adrienne Cupples, Thomas Quertermous, Winfried März, Christian Hengstenberg, Stefan Blankenberg, Willem H. Ouwehand, Alistair S. Hall, Panos Deloukas, John R. Thompson, Kari Stefansson, Robert Roberts, Unnur Thorsteinsdottir, Christopher J. O’Donnell, Ruth McPherson, Jeanette Erdmann, Nilesh J. Samani

Nat Genet. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Nat Genet. 2011 Mar 6; 43(4): 333–338. Published online 2011 Mar 6. doi: 10.1038/ng.784

PMCID:: PMC3119261

Abstract Article PDF–405K

Select item 45014316.

The structure of the human mitochondrial ribosome

Alexey Amunts, Alan Brown, Jaan Toots, Sjors H. W. Scheres, V. Ramakrishnan

Science. Author manuscript; available in PMC 2015 Oct 3.

Published in final edited form as: Science. 2015 Apr 3; 348(6230): 95–98. Published online 2015 Apr 2. doi: 10.1126/science.aaa1193

PMCID:: PMC4501431

Abstract Article PDF–1.7M

Select item 85695937.

Neddylation modification of the U3 snoRNA-binding protein RRP9 by Smurf1 promotes tumorigenesis

Meng-ge Du, Fan Liu, Yan Chang, Shuai Tong, Wei Liu, Yu-jiao Chen, Ping Xie

J Biol Chem. 2021 Nov; 297(5): 101307. Published online 2021 Oct 15. doi: 10.1016/j.jbc.2021.101307

Correction in:: J Biol Chem. 2022 Nov; 298(11): 102567.

PMCID:: PMC8569593

Abstract Article PDF–4.2M

Select item 108508188.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 66200289.

Mitochondrial ClpP-mediated proteolysis induces selective cancer cell lethality

Jo Ishizawa, Sarah F. Zarabi, R. Eric Davis, Ondrej Halgas, Takenobu Nii, Yulia Jitkova, Ran Zhao, Jonathan St-Germain, Lauren E. Heese, Grace Egan, Vivian R. Ruvolo, Samir H. Barghout, Yuki Nishida, Rose Hurren, Wencai Ma, Marcela Gronda, Todd Link, Keith Wong, Mark Mabanglo, Kensuke Kojima, Gautam Borthakur, Neil MacLean, John Man Chun Ma, Andrew B. Leber, Mark D. Minden, Walid Houry, Hagop Kantarjian, Martin Stogniew, Brian Raught, Emil F. Pai, Aaron D. Schimmer, Michael Andreeff

Cancer Cell. Author manuscript; available in PMC 2020 May 13.

Published in final edited form as: Cancer Cell. 2019 May 13; 35(5): 721–737.e9. Published online 2019 May 2. doi: 10.1016/j.ccell.2019.03.014

PMCID:: PMC6620028

Abstract Article PDF–2.9M

Select item 284527110.

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

Ricarda Richter, Joanna Rorbach, Aleksandra Pajak, Paul M Smith, Hans J Wessels, Martijn A Huynen, Jan A Smeitink, Robert N Lightowlers, Zofia M Chrzanowska-Lightowlers

EMBO J. 2010 Mar 17; 29(6): 1116–1125. Published online 2010 Feb 25. doi: 10.1038/emboj.2010.14

PMCID:: PMC2845271

Abstract Article PDF–1.3M

Select item 794896411.

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1

Lee D. Harris, Janic Le Pen, Nico Scholz, Juliusz Mieszczanek, Natalie Vaughan, Simon Davis, Georgina Berridge, Benedikt M. Kessler, Mariann Bienz, Julien D.F. Licchesi

J Biol Chem. 2021 Jan-Jun; 296: 100246. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015162

PMCID:: PMC7948964

Abstract Article PDF–2.7M

Select item 738231312.

MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation

Gayoung Seo, Han Han, Rebecca Elizabeth Vargas, Bing Yang, Xu Li, Wenqi Wang

Cell Rep. Author manuscript; available in PMC 2020 Jul 25.

Published in final edited form as: Cell Rep. 2020 Jul 7; 32(1): 107860. doi: 10.1016/j.celrep.2020.107860

PMCID:: PMC7382313

Abstract Article PDF–2.6M

Select item 702912313.

The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival

Yuanming He, Siyu Wang, Jiefei Tong, Shuoyi Jiang, Ye Yang, Zubin Zhang, Yujia Xu, Yuanying Zeng, Biyin Cao, Michael F. Moran, Xinliang Mao

J Biol Chem. 2020 Feb 14; 295(7): 2084–2096. Published online 2019 Dec 10. doi: 10.1074/jbc.RA119.010724

PMCID:: PMC7029123

Abstract Article PDF–3.6M

Select item 632118514.

High Throughput Chemical Screening Reveals Multiple Regulatory Proteins on FOXA1 in Breast Cancer Cell Lines

Shixiong Wang, Sachin Kumar Singh, Madhumohan R. Katika, Sandra Lopez-Aviles, Antoni Hurtado

Int J Mol Sci. 2018 Dec; 19(12): 4123. Published online 2018 Dec 19. doi: 10.3390/ijms19124123

PMCID:: PMC6321185

Abstract Article PDF–2.8M

Select item 471456115.

KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II

Ryan P. McNamara, Jonathan E. Reeder, Elizabeth A. McMillan, Curtis W. Bacon, Jennifer L. McCann, Iván D’Orso

Mol Cell. Author manuscript; available in PMC 2017 Jan 7.

Published in final edited form as: Mol Cell. 2016 Jan 7; 61(1): 39–53. Published online 2015 Dec 24. doi: 10.1016/j.molcel.2015.11.004

PMCID:: PMC4714561

Abstract Article PDF–2.2M

Select item 468531216.

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis

Giorgio Oliviero, Nayla Munawar, Ariane Watson, Gundula Streubel, Gwendolyn Manning, Vivian Bardwell, Adrian P. Bracken, Gerard Cagney

Sci Rep. 2015; 5: 18388. Published online 2015 Dec 21. doi: 10.1038/srep18388

PMCID:: PMC4685312

Abstract Article PDF–1.5M

Select item 885704917.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

Select item 790504018.

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer

Hantao Wang, Junjie Xing, Wei Wang, Guifen Lv, Haiyan He, Yeqing Lu, Mei Sun, Haiyan Chen, Xu Li

Front Cell Dev Biol. 2020; 8: 601502. Published online 2021 Feb 11. doi: 10.3389/fcell.2020.601502

PMCID:: PMC7905040

Abstract Article PDF–3.2M

Select item 622622519.

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation

Jaewoo Choi, Anita Saraf, Laurence Florens, Michael P. Washburn, Luca Busino

Cell Cycle. 2018; 17(18): 2243–2255. Published online 2018 Sep 25. doi: 10.1080/15384101.2018.1522912

PMCID:: PMC6226225

Abstract Article PDF–1.7M

Select item 605223620.

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease

Isaac Bishof, Eric B. Dammer, Duc M. Duong, Sean R. Kundinger, Marla Gearing, James J. Lah, Allan I. Levey, Nicholas T. Seyfried

J Biol Chem. 2018 Jul 13; 293(28): 11047–11066. Published online 2018 May 25. doi: 10.1074/jbc.RA118.001747

PMCID:: PMC6052236

Abstract Article PDF–5.1M

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