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Select item 88414351.

Pharmacogenomics of celiprolol – evidence for a role of P‐glycoprotein and organic anion transporting polypeptide 1A2 in celiprolol pharmacokinetics

Päivi Hirvensalo, Aleksi Tornio, Tuija Tapaninen, Maria Paile‐Hyvärinen, Mikko Neuvonen, Janne T. Backman, Mikko Niemi

Clin Transl Sci. 2022 Feb; 15(2): 409–421. Published online 2021 Sep 29. doi: 10.1111/cts.13159

PMCID:: PMC8841435

Abstract Article PDF–615K

Select item 44030982.

Human organic anion transporting polypeptide 1A2 (OATP1A2) mediates cellular uptake of all-trans-retinol in human retinal pigmented epithelial cells

Ting Chan, Ling Zhu, Michele C Madigan, Ke Wang, Weiyong Shen, Mark C Gillies, Fanfan Zhou

Br J Pharmacol. 2015 May; 172(9): 2343–2353. Published online 2015 Feb 27. doi: 10.1111/bph.13060

PMCID:: PMC4403098

Abstract Article PDF–1022K

Select item 37872383.

Functional Analysis of Novel Polymorphisms in the Human SLCO1A2 Gene that Encodes the Transporter OATP1A2

Fanfan Zhou, Jian Zheng, Ling Zhu, Andreas Jodal, Pei H. Cui, Mark Wong, Howard Gurney, W. Bret Church, Michael Murray

AAPS J. 2013 Oct; 15(4): 1099–1108. Published online 2013 Aug 6. doi: 10.1208/s12248-013-9515-1

PMCID:: PMC3787238

Abstract Article PDF–529K

Select item 34767324.

Environmental and genetic factors affecting transport of imatinib by OATP1A2

K Eechoute, RM Franke, WJ Loos, LA Scherkenbach, I Boere, J Verweij, H Gurney, RB Kim, RG Tirona, RHJ Mathijssen, A Sparreboom

Clin Pharmacol Ther. Author manuscript; available in PMC 2012 Oct 19.

Published in final edited form as: Clin Pharmacol Ther. 2011 Jun; 89(6): 816–820. Published online 2011 Apr 20. doi: 10.1038/clpt.2011.42

PMCID:: PMC3476732

Abstract Article PDF–1.8M

Select item 30581695.

Protein kinase C regulates the internalization and function of the human organic anion transporting polypeptide 1A2

Fanfan Zhou, Andy C Lee, Katja Krafczyk, Ling Zhu, Michael Murray

Br J Pharmacol. 2011 Mar; 162(6): 1380–1388. doi: 10.1111/j.1476-5381.2010.01144.x

PMCID:: PMC3058169

Abstract Article PDF–941K

Select item 60383526.

Replication of progressive supranuclear palsy genome-wide association study identifies SLCO1A2 and DUSP10 as new susceptibility loci

Monica Y. Sanchez-Contreras, Naomi Kouri, Casey N. Cook, Daniel J. Serie, Michael G. Heckman, NiCole A. Finch, Richard J. Caselli, Ryan J. Uitti, Zbigniew K. Wszolek, Neill Graff-Radford, Leonard Petrucelli, Li-San Wang, Gerard D. Schellenberg, Dennis W. Dickson, Rosa Rademakers, Owen A. Ross

Mol Neurodegener. 2018; 13: 37. Published online 2018 Jul 9. doi: 10.1186/s13024-018-0267-3

PMCID:: PMC6038352

Abstract Article PDF–1.2M

Select item 25970477.

Interplay between the nuclear receptor PXR and the uptake transporter OATP1A2 selectively enhances estrogen effects in breast cancer

Henriette E. Meyer zu Schwabedissen, Rommel G. Tirona, Cindy S. Yip, Richard H. Ho, Richard B. Kim

Cancer Res. Author manuscript; available in PMC 2009 Nov 15.

Published in final edited form as: Cancer Res. 2008 Nov 15; 68(22): 9338–9347. doi: 10.1158/0008-5472.CAN-08-0265

PMCID:: PMC2597047

Abstract Article PDF–2.2M

Select item 70996318.

SLCO1A2, SLCO1B1 and SLCO2B1 polymorphisms influences chloroquine and primaquine treatment in Plasmodium vivax malaria

Vinicius A Sortica, Juliana D Lindenau, Maristela G Cunha, Maria Deise O Ohnishi, Ana Maria R Ventura, Ândrea KC Ribeiro-dos-Santos, Sidney EB Santos, Luciano SP Guimarães, Mara H Hutz

Pharmacogenomics. 2017 Oct; 18(15): 1393–1400. Published online 2017 Oct 4. doi: 10.2217/pgs-2017-0077

PMCID:: PMC7099631

Abstract Article PDF–668K

Select item 51985129.

Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance

Hannah H. Lee, Brenda F. Leake, Richard B. Kim, Richard H. Ho

Mol Pharmacol. 2017 Jan; 91(1): 14–24. Published online 2017 Jan. doi: 10.1124/mol.116.105544

PMCID:: PMC5198512

Abstract Article PDF–1.4M

Select item 485941010.

HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms

Ruben C Hartkoorn, Wai San Kwan, Victoria Shallcross, Ammara Chaikan, Neill Liptrott, Deirdre Egan, J Enrique Salcedo Sora, Chloe E James, Sara Gibbons, Pat G Bray, David J Back, Saye H Khoo, Andrew Owen

Pharmacogenet Genomics. Author manuscript; available in PMC 2016 May 6.

Published in final edited form as: Pharmacogenet Genomics. 2010 Feb; 20(2): 112–120. doi: 10.1097/FPC.0b013e328335b02d

PMCID:: PMC4859410

Abstract Article PDF–2.7M

Select item 398424911.

PDZK1 and NHERF1 Regulate the Function of Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2) by Modulating Its Subcellular Trafficking and Stability

Jian Zheng, Ting Chan, Florence Shin Gee Cheung, Ling Zhu, Michael Murray, Fanfan Zhou

PLoS One. 2014; 9(4): e94712. Published online 2014 Apr 11. doi: 10.1371/journal.pone.0094712

PMCID:: PMC3984249

Abstract Article PDF–1.6M

Select item 288402912.

The role of organic anion-transporting polypeptides and their common genetic variants in mycophenolic acid pharmacokinetics

Nicolas Picard, Sook Wah Yee, J. B. Woillard, Yvon Lebranchu, Yannick Le Meur, Kathleen M. Giacomini, Pierre Marquet

Clin Pharmacol Ther. Author manuscript; available in PMC 2010 Jun 14.

Published in final edited form as: Clin Pharmacol Ther. 2010 Jan; 87(1): 100–108. Published online 2009 Nov 4. doi: 10.1038/clpt.2009.205

PMCID:: PMC2884029

Abstract Article

Select item 279304013.

Germline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With Methotrexate Pharmacokinetics and Clinical Effects

Lisa R. Treviño, Noriko Shimasaki, Wenjian Yang, John C. Panetta, Cheng Cheng, Deqing Pei, Diana Chan, Alex Sparreboom, Kathleen M. Giacomini, Ching-Hon Pui, William E. Evans, Mary V. Relling

J Clin Oncol. 2009 Dec 10; 27(35): 5972–5978. Published online 2009 Nov 9. doi: 10.1200/JCO.2008.20.4156

PMCID:: PMC2793040

Abstract Article PDF–224K

Select item 311255814.

The expression of thyroid hormone transporters in the human fetal cerebral cortex during early development and in N-Tera-2 neurodifferentiation

S-Y Chan, A Martín-Santos, L S Loubière, A M González, B Stieger, A Logan, C J McCabe, J A Franklyn, M D Kilby

J Physiol. 2011 Jun 1; 589(Pt 11): 2827–2845. Published online 2011 Mar 21. doi: 10.1113/jphysiol.2011.207290

PMCID:: PMC3112558

Abstract Article PDF–564K

Select item 312547615.

Identification of common variants influencing risk of the tauopathy Progressive Supranuclear Palsy

Günter U. Höglinger, Nadine M. Melhem, Dennis W. Dickson, Patrick M.A. Sleiman, Li-San Wang, Lambertus Klei, Rosa Rademakers, Rohan de Silva, Irene Litvan, David E. Riley, John C. van Swieten, Peter Heutink, Zbigniew K. Wszolek, Ryan J. Uitti, Jana Vandrovcova, Howard I. Hurtig, Rachel G. Gross, Walter Maetzler, Stefano Goldwurm, Eduardo Tolosa, Barbara Borroni, Pau Pastor, PSP Genetics Study Group, Laura B. Cantwell, Mi Ryung Han, Allissa Dillman, Marcel P. van der Brug, J Raphael Gibbs, Mark R. Cookson, Dena G. Hernandez, Andrew B. Singleton, Matthew J. Farrer, Chang-En Yu, Lawrence I. Golbe, Tamas Revesz, John Hardy, Andrew J. Lees, Bernie Devlin, Hakon Hakonarson, Ulrich Müller, Gerard D. Schellenberg

Nat Genet. Author manuscript; available in PMC 2012 Jan 1.

Published in final edited form as: Nat Genet. 2011 Jul; 43(7): 699–705. Published online 2011 Jun 19. doi: 10.1038/ng.859

PMCID:: PMC3125476

Abstract Article PDF–1.4M

Select item 8679016.

Antisense Promoter of Human L1 Retrotransposon Drives Transcription of Adjacent Cellular Genes

Mart Speek

Mol Cell Biol. 2001 Mar; 21(6): 1973–1985. doi: 10.1128/MCB.21.6.1973-1985.2001

PMCID:: PMC86790

Abstract Article PDF–958K

Select item 919023317.

Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier

Raymond K. Hau, Robert R. Klein, Stephen H. Wright, Nathan J. Cherrington

Drug Metab Dispos. 2022 Jun; 50(6): 770–780. Published online 2022 Jun. doi: 10.1124/dmd.121.000748

PMCID:: PMC9190233

Abstract Article PDF–2.8M

Select item 270133618.

Genome-wide association meta-analysis for total serum bilirubin levels

Andrew D. Johnson, Maryam Kavousi, Albert V. Smith, Ming-Huei Chen, Abbas Dehghan, Thor Aspelund, Jing-Ping Lin, Cornelia M. van Duijn, Tamara B. Harris, L. Adrienne Cupples, Andre G. Uitterlinden, Lenore Launer, Albert Hofman, Fernando Rivadeneira, Bruno Stricker, Qiong Yang, Christopher J. O'Donnell, Vilmundur Gudnason, Jacqueline C. Witteman

Hum Mol Genet. 2009 Jul 15; 18(14): 2700–2710. Published online 2009 May 4. doi: 10.1093/hmg/ddp202

PMCID:: PMC2701336

Abstract Article PDF–237K

Select item 287520119.

Identification of Type 2 Diabetes-associated combination of SNPs using Support Vector Machine

Hyo-Jeong Ban, Jee Yeon Heo, Kyung-Soo Oh, Keun-Joon Park

BMC Genet. 2010; 11: 26. Published online 2010 Apr 23. doi: 10.1186/1471-2156-11-26

PMCID:: PMC2875201

Abstract Article PDF–1.0M

Select item 322964120.

Image-Based Genome-Wide siRNA Screen Identifies Selective Autophagy Factors

Anthony Orvedahl, Rhea Sumpter, Jr., Guanghua Xiao, Aylwin Ng, Zhongju Zou, Yi Tang, Masahiro Narimatsu, Christopher Gilpin, Qihua Sun, Michael Roth, Christian V. Forst, Jeffrey L. Wrana, Ying E. Zhang, Katherine Luby-Phelps, Ramnik Xavier, Yang Xie, Beth Levine

Nature. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: Nature. 2011 Dec 1; 480(7375): 113–117. doi: 10.1038/nature10546

PMCID:: PMC3229641

Abstract Article PDF–2.3M

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