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1.
Genetic preservation of SLC22A3 in the Admixed and Xhosa populations living in the Western Cape
Brendon Pearce, Clifford Jacobs, Mongi Benjeddou
Mol Biol Rep. 2023; 50(12): 10199–10206. Published online 2023 Nov 4. doi: 10.1007/s11033-023-08884-6
PMCID:
PMC10676312
AbstractArticlePDF–1.0M
2.
Genetic variants in SLC22A3 contribute to the susceptibility to colorectal cancer
Anjing Ren, Shanwen Sun, Shuwei Li, Tao Chen, Yongqian Shu, Mulong Du, Lingjun Zhu
Int J Cancer. 2019 Jul 1; 145(1): 154–163. Published online 2019 Jan 3. doi: 10.1002/ijc.32079
PMCID:
PMC6590332
AbstractArticlePDF–902K
3.
OCT3 promoter haplotype is associated with metformin pharmacokinetics in Koreans
Eun Young Kwon, Jae-Yong Chung, Hyo Jin Park, Bo Min Kim, Minsuk Kim, Ji Ha Choi
Sci Rep. 2018; 8: 16965. Published online 2018 Nov 16. doi: 10.1038/s41598-018-35322-6
PMCID:
PMC6240047
AbstractArticlePDF–1.5M
4.
Epigenetic alterations of a novel antioxidant gene SLC22A3 predispose susceptible individuals to increased risk of esophageal cancer
Ji-Xian Xiong, Yan-Song Wang, Jingyi Sheng, Di Xiang, Tu-Xiong Huang, Bin-Bin Tan, Cui-Mian Zeng, Hua-Hui Li, Jiao Yang, Stephen J. Meltzer, Yuriko Mori, Yan-Ru Qin, Xin-Yuan Guan, Li Fu
Int J Biol Sci. 2018; 14(12): 1658–1668. Published online 2018 Sep 7. doi: 10.7150/ijbs.28482
PMCID:
PMC6216027
AbstractArticlePDF–1.9M
5.
RNA editing of SLC22A3 drives early tumor invasion and metastasis in familial esophageal cancer
Li Fu, Yan-Ru Qin, Xiao-Yan Ming, Xian-Bo Zuo, Yu-Wen Diao, Li-Yi Zhang, Jiaoyu Ai, Bei-Lei Liu, Tu-Xiong Huang, Ting-Ting Cao, Bin-Bin Tan, Di Xiang, Chui-Mian Zeng, Jing Gong, Qiangfeng Zhang, Sui-Sui Dong, Juan Chen, Haibo Liu, Jian-Lin Wu, Robert Z. Qi, Dan Xie, Li-Dong Wang, Xin-Yuan Guan
Proc Natl Acad Sci U S A. 2017 Jun 6; 114(23): E4631–E4640. Published online 2017 May 22. doi: 10.1073/pnas.1703178114
PMCID:
PMC5468658
AbstractArticlePDF–2.0M
6.
SLC22A3 polymorphisms do not modify pancreatic cancer risk, but may influence overall patient survival
Beatrice Mohelnikova-Duchonova, Ondrej Strouhal, David J. Hughes, Ivana Holcatova, Martin Oliverius, Zdenek Kala, Daniele Campa, Cosmeri Rizzato, Federico Canzian, Raffaele Pezzilli, Renata Talar-Wojnarowska, Ewa Malecka-Panas, Cosimo Sperti, Carlo Federico Zambon, Sergio Pedrazzoli, Paola Fogar, Anna Caterina Milanetto, Gabriele Capurso, Gianfranco Delle Fave, Roberto Valente, Maria Gazouli, Giuseppe Malleo, Rita Teresa Lawlor, Oliver Strobel, Thilo Hackert, Nathalia Giese, Pavel Vodicka, Ludmila Vodickova, Stefano Landi, Francesca Tavano, Domenica Gioffreda, Ada Piepoli, Valerio Pazienza, Andrea Mambrini, Mariangela Pedata, Maurizio Cantore, Franco Bambi, Stefano Ermini, Niccola Funel, Radmila Lemstrova, Pavel Soucek
Sci Rep. 2017; 7: 43812. Published online 2017 Mar 8. doi: 10.1038/srep43812
PMCID:
PMC5341046
AbstractArticlePDF–646K
7.
A Solute Carrier Family 22 Member 3 Variant rs3088442 G→A Associated with Coronary Heart Disease Inhibits Lipopolysaccharide-induced Inflammatory Response
Lu Li, Meian He, Li Zhou, Xiaoping Miao, Fangqing Wu, Suli Huang, Xiayun Dai, Tian Wang, Tangchun Wu
J Biol Chem. 2015 Feb 27; 290(9): 5328–5340. Published online 2015 Jan 5. doi: 10.1074/jbc.M114.584953
PMCID:
PMC4342451
AbstractArticlePDF–3.7M
8.
Genetic Variant rs7758229 in 6q26–q27 Is Not Associated with Colorectal Cancer Risk in a Chinese Population
Lingjun Zhu, Mulong Du, Dongying Gu, Lan Ma, Haiyan Chu, Na Tong, Jinfei Chen, Zhengdong Zhang, Meilin Wang
PLoS One. 2013; 8(3): e59256. Published online 2013 Mar 12. doi: 10.1371/journal.pone.0059256
PMCID:
PMC3595231
AbstractArticlePDF–126K
9.
Genetic and Epigenetic Regulation of the Organic Cation Transporter 3, SLC22A3
Ligong Chen, Chibo Hong, Eugene C. Chen, Sook Wah Yee, Lu Xu, Emil U. Almof, Christopher Wen, Kacyn Fujii, Susan J. Johns, Doug Stryke, Thomas E. Ferrin, Jeff Simko, Xin Chen, Joseph F. Costello, Kathleen M. Giacomini
Pharmacogenomics J. Author manuscript; available in PMC 2013 Oct 1.
Published in final edited form as: Pharmacogenomics J. 2013 Apr; 13(2): 110–120. Published online 2012 Jan 10. doi: 10.1038/tpj.2011.60
PMCID:
PMC3396779
AbstractArticlePDF–1.3M
10.
Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3
Martina Hayer-Zillgen, Michael Brüss, Heinz Bönisch
Br J Pharmacol. 2002 Jul; 136(6): 829–836. doi: 10.1038/sj.bjp.0704785
PMCID:
PMC1573414
AbstractArticlePDF–252K
11.
Release of non-neuronal acetylcholine from the isolated human placenta is mediated by organic cation transporters
Ignaz Wessler, Elisabeth Roth, Carola Deutsch, Peter Brockerhoff, Fernando Bittinger, Charles James Kirkpatrick, Heinz Kilbinger
Br J Pharmacol. 2001 Nov; 134(5): 951–956. doi: 10.1038/sj.bjp.0704335
PMCID:
PMC1573028
AbstractArticlePDF–157K
12.
Protein expression of ABCC2 and SLC22A3 associates with prognosis of pancreatic adenocarcinoma
Lenka Cervenkova, Ondrej Vycital, Jan Bruha, Jachym Rosendorf, Richard Palek, Vaclav Liska, Ondrej Daum, Beatrice Mohelnikova-Duchonova, Pavel Soucek
Sci Rep. 2019; 9: 19782. Published online 2019 Dec 24. doi: 10.1038/s41598-019-56059-w
PMCID:
PMC6930301
AbstractArticlePDF–1.6M
13.
Cytoplasmic dsRNA induces the expression of OCT3/4 and NANOG mRNAs in differentiated human cells
Guanming Wang, Takahisa Kouwaki, Kazuki Mugikura, Masaaki Okamoto, Hiromi Takaki, Kenji Funami, Tsukasa Seya, Hiroyuki Oshiumi
J Biol Chem. 2019 Dec 13; 294(50): 18969–18979. Published online 2019 Oct 15. doi: 10.1074/jbc.RA119.009783
PMCID:
PMC6916484
AbstractArticlePDF–4.1M
14.
Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population
R Cui, Y Okada, S G Jang, J L Ku, J G Park, Y Kamatani, N Hosono, T Tsunoda, V Kumar, C Tanikawa, N Kamatani, R Yamada, M Kubo, Y Nakamura, K Matsuda
Gut. 2011 Jun; 60(6): 799–805. Published online 2011 Jan 17. doi: 10.1136/gut.2010.215947
PMCID:
PMC3095478
AbstractArticlePDF–501K
15.
Serotonin homeostasis in the materno-foetal interface at term: Role of transporters (SERT/SLC6A4 and OCT3/SLC22A3) and monoamine oxidase A (MAO-A) in uptake and degradation of serotonin by human and rat term placenta
Rona Karahoda, Hana Horackova, Petr Kastner, Andreas Matthios, Lukas Cerveny, Radim Kucera, Marian Kacerovsky, Jurjen Duintjer Tebbens, Alexandre Bonnin, Cilia Abad, Frantisek Staud
Acta Physiol (Oxf) Author manuscript; available in PMC 2021 Aug 6.
Published in final edited form as: Acta Physiol (Oxf). 2020 Aug; 229(4): e13478. Published online 2020 May 18. doi: 10.1111/apha.13478
PMCID:
PMC8345021
AbstractArticlePDF–1.4M
16.
PHACTR1 and SLC22A3 gene polymorphisms are associated with reduced coronary artery disease risk in the male Chinese Han population
Qingbin Zhao, Huiyi Wei, Dandan Liu, Baolan Shi, Lei Li, Mengdan Yan, Xiyang Zhang, Fengjiao Wang, Yongri Ouyang
Oncotarget. 2017 Jan 3; 8(1): 658–663. Published online 2016 Nov 22. doi: 10.18632/oncotarget.13506
PMCID:
PMC5352186
AbstractArticlePDF–1.7M
17.
Targeted Disruption of Organic Cation Transporter 3 Attenuates the Pharmacologic Response to Metformin
Eugene C. Chen, Xiaomin Liang, Sook Wah Yee, Ethan G. Geier, Sophie L. Stocker, Ligong Chen, Kathleen M. Giacomini
Mol Pharmacol. 2015 Jul; 88(1): 75–83. Published online 2015 Jul. doi: 10.1124/mol.114.096776
PMCID:
PMC4468641
AbstractArticlePDF–914K
18.
Expression of Wnt3 activates Wnt/β-catenin pathway and promotes EMT-like phenotype in trastuzumab resistant HER2-overexpressing breast cancer cells
Yanyuan Wu, Charles Ginther, Juri Kim, Nicole Mosher, Seyung Chung, Dennis Slamon, Jaydutt V. Vadgama
Mol Cancer Res. Author manuscript; available in PMC 2013 Dec 1.
Published in final edited form as: Mol Cancer Res. 2012 Dec; 10(12): 1597–1606. Published online 2012 Oct 15. doi: 10.1158/1541-7786.MCR-12-0155-T
PMCID:
PMC3732195
AbstractArticlePDF–1.3M
19.
Lack of association between four SNPs in the SLC22A3-LPAL2-LPA gene cluster and coronary artery disease in a Chinese Han population: a case control study
Xiaofei Lv, Yuan Zhang, Shaoqi Rao, Fengqiong Liu, Xiaoyu Zuo, Dongfang Su, Min Wang, Min Xia, Honghui Guo, Dan Feng, Changjiang Hong, Dan Li, Wenjun Ma, Ping Ouyang, Xinrui Li, Xiang Feng, Yan Yang, Wenhua Ling, Jian Qiu
Lipids Health Dis. 2012; 11: 128. Published online 2012 Oct 4. doi: 10.1186/1476-511X-11-128
PMCID:
PMC3478218
AbstractArticlePDF–389K
20.
Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis
Chiara Grisanzio, Lillian Werner, David Takeda, Bisola C. Awoyemi, Mark M. Pomerantz, Hiroki Yamada, Prasanna Sooriakumaran, Brian D. Robinson, Robert Leung, Anna C. Schinzel, Ian Mills, Helen Ross-Adams, David E. Neal, Masahito Kido, Toshihiro Yamamoto, Gillian Petrozziello, Edward C. Stack, Rosina Lis, Philip W. Kantoff, Massimo Loda, Oliver Sartor, Shin Egawa, Ashutosh K. Tewari, William C. Hahn, Matthew L. Freedman
Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28): 11252–11257. Published online 2012 Jun 22. doi: 10.1073/pnas.1200853109
PMCID:
PMC3396469
AbstractArticlePDF–755K

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