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Select item 111601771.

DNA hypermethylation and histone hypoacetylation of the HLTF gene are associated with reduced expression in gastric carcinoma

Yoichi Hamai, Naohide Oue, Yoshitsugu Mitani, Hirofumi Nakayama, Reiko Ito, Keisuke Matsusaki, Kazuhiro Yoshida, Tetsuya Toge, Wataru Yasui

Cancer Sci. 2003 Aug; 94(8): 692–698. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01504.x

PMCID:: PMC11160177

Abstract Article PDF–244K

Select item 111316142.

The Helicase-Like Transcription Factor and its implication in cancer progression

G. Debauve, A. Capouillez, A. Belayew, S. Saussez

Cell Mol Life Sci. 2008 Feb; 65(4): 591–604. Published online 2007 Nov 24. doi: 10.1007/s00018-007-7392-4

PMCID:: PMC11131614

Abstract Article PDF–1.3M

Select item 104009473.

The helicase-like transcription factor redirects the autophagic flux and restricts human T cell leukemia virus type 1 infection

Aurélie Beauvois, Hélène Gazon, Pradeep Singh Chauhan, Majeed Jamakhani, Jean-Rock Jacques, Marc Thiry, Emmanuel Dejardin, Emmanuel Di Valentin, Jean-Claude Twizere, Jean-Marie Péloponèse, Makon-Sébastien Njock, Jun-Ichirou Yasunaga, Masao Matsuoka, Malik Hamaïdia, Luc Willems

Proc Natl Acad Sci U S A. 2023 Aug 1; 120(31): e2216127120. Published online 2023 Jul 24. doi: 10.1073/pnas.2216127120

PMCID:: PMC10400947

Abstract Article PDF–5.5M

Select item 73059984.

HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis

Gongshi Bai, Chames Kermi, Henriette Stoy, Carl Schiltz, Julien Bacal, Angela M. Zaino, M. Kyle Hadden, Brandt Eichman, Massimo Lopes, Karlene A. Cimprich

Mol Cell. Author manuscript; available in PMC 2021 Jun 18.

Published in final edited form as: Mol Cell. 2020 Jun 18; 78(6): 1237–1251.e7. Published online 2020 May 21. doi: 10.1016/j.molcel.2020.04.031

PMCID:: PMC7305998

Abstract Article PDF–2.9M

Select item 59028965.

Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC)

Ludovic Dhont, Melania Pintilie, Ethan Kaufman, Roya Navab, Shirley Tam, Arsène Burny, Frances Shepherd, Alexandra Belayew, Ming-Sound Tsao, Céline Mascaux

BMC Cancer. 2018; 18: 429. Published online 2018 Apr 16. doi: 10.1186/s12885-018-4215-y

PMCID:: PMC5902896

Abstract Article PDF–1.1M

Select item 44754616.

HLTF’s Ancient HIRAN Domain Binds 3′-DNA Ends to Drive Replication Fork Reversal

Andrew C. Kile, Diana A. Chavez, Julien Bacal, Sherif Eldirany, Dmitry M. Korzhnev, Irina Bezsonova, Brandt F. Eichman, Karlene A. Cimprich

Mol Cell. Author manuscript; available in PMC 2016 Jun 18.

Published in final edited form as: Mol Cell. 2015 Jun 18; 58(6): 1090–1100. Published online 2015 Jun 4. doi: 10.1016/j.molcel.2015.05.013

PMCID:: PMC4475461

Abstract Article PDF–2.7M

Select item 41079607.

Helicase-like transcription factor: a new marker of well-differentiated thyroid cancers

Vanessa Arcolia, Paula Paci, Ludovic Dhont, Gilbert Chantrain, Nicolas Sirtaine, Christine Decaestecker, Myriam Remmelink, Alexandra Belayew, Sven Saussez

BMC Cancer. 2014; 14: 492. Published online 2014 Jul 8. doi: 10.1186/1471-2407-14-492

PMCID:: PMC4107960

Abstract Article PDF–1.8M

Select item 31615878.

Coordinated protein and DNA remodeling by human HLTF on stalled replication fork

Yathish Jagadheesh Achar, David Balogh, Lajos Haracska

Proc Natl Acad Sci U S A. 2011 Aug 23; 108(34): 14073-14078. Published online 2011 Jul 27. doi: 10.1073/pnas.1101951108

PMCID:: PMC3161587

Abstract Article PDF–830K

Select item 28122319.

Role of Double-Stranded DNA Translocase Activity of Human HLTF in Replication of Damaged DNA

András Blastyák, Ildikó Hajdú, Ildikó Unk, Lajos Haracska

Mol Cell Biol. 2010 Feb; 30(3): 684–693. Published online 2009 Nov 30. doi: 10.1128/MCB.00863-09

PMCID:: PMC2812231

Abstract Article PDF–1.2M

Select item 12368710.

HLTF gene silencing in human colon cancer

Helen R. Moinova, Wei-Dong Chen, Lanlan Shen, Dominic Smiraglia, Joseph Olechnowicz, Lakshmeswari Ravi, Lakshmi Kasturi, Lois Myeroff, Christoph Plass, Ramon Parsons, John Minna, James K. V. Willson, Sylvan B. Green, Jean-Pierre Issa, Sanford D. Markowitz

Proc Natl Acad Sci U S A. 2002 Apr 2; 99(7): 4562–4567. Published online 2002 Mar 19. doi: 10.1073/pnas.062459899

Correction in:: Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13): 9081.

PMCID:: PMC123687

Abstract Article PDF–293K

Select item 1110851611.

The helicase-like transcription factor (HLTF) in cancer: loss of function or oncomorphic conversion of a tumor suppressor?

Ludovic Dhont, Céline Mascaux, Alexandra Belayew

Cell Mol Life Sci. 2016 Jan; 73(1): 129–145. Published online 2015 Oct 15. doi: 10.1007/s00018-015-2060-6

PMCID:: PMC11108516

Abstract Article PDF–970K

Select item 717531512.

The Human RAD5 Homologs, HLTF and SHPRH, Have Separate Functions in DNA Damage Tolerance Dependent on the DNA Lesion Type

Mareike Seelinger, Caroline Krogh Søgaard, Marit Otterlei

Biomolecules. 2020 Mar; 10(3): 463. Published online 2020 Mar 17. doi: 10.3390/biom10030463

PMCID:: PMC7175315

Abstract Article PDF–4.3M

Select item 651105713.

HIV-1 Vpr counteracts HLTF-mediated restriction of HIV-1 infection in T cells

Junpeng Yan, Ming-Chieh Shun, Yi Zhang, Caili Hao, Jacek Skowronski

Proc Natl Acad Sci U S A. 2019 May 7; 116(19): 9568–9577. Published online 2019 Apr 24. doi: 10.1073/pnas.1818401116

PMCID:: PMC6511057

Abstract Article PDF–1.5M

Select item 621894914.

Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress

Min Peng, Ke Cong, Nicholas J. Panzarino, Sumeet Nayak, Jennifer Calvo, Bin Deng, Lihua Julie Zhu, Monika Morocz, Lili Hegedus, Lajos Haracska, Sharon B. Cantor

Cell Rep. Author manuscript; available in PMC 2018 Nov 6.

Published in final edited form as: Cell Rep. 2018 Sep 18; 24(12): 3251–3261. doi: 10.1016/j.celrep.2018.08.065

PMCID:: PMC6218949

Abstract Article PDF–1.4M

Select item 578855315.

ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells

Shengfu Piao, Rani Ojha, Vito W. Rebecca, Arabinda Samanta, Xiao-hong Ma, Quentin Mcafee, Michael C. Nicastri, Meghan Buckley, Eric Brown, Jeffrey D. Winkler, Phyllis A. Gimotty, Ravi K. Amaravadi

Autophagy. 2017; 13(12): 2056–2071. Published online 2017 Oct 5. doi: 10.1080/15548627.2017.1377377