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Select item 80051321.

Nox2 Inhibition Regulates Stress Response and Mitigates Skeletal Muscle Fiber Atrophy during Simulated Microgravity

John M. Lawler, Jeffrey M. Hord, Pat Ryan, Dylan Holly, Mariana Janini Gomes, Dinah Rodriguez, Vinicius Guzzoni, Erika Garcia-Villatoro, Chase Green, Yang Lee, Sarah Little, Marcela Garcia, Lorrie Hill, Mary-Catherine Brooks, Matthew S. Lawler, Nicolette Keys, Amin Mohajeri, Khaled Y. Kamal

Int J Mol Sci. 2021 Mar; 22(6): 3252. Published online 2021 Mar 23. doi: 10.3390/ijms22063252

PMCID:: PMC8005132

Abstract Article PDF–27M

Select item 58787142.

Aortic Dysfunction in Metabolic Syndrome Mediated by Perivascular Adipose Tissue TNFα and NOX2 Dependent Pathway

Evan DeVallance, Kayla W Branyan, Kent Lemaster, I. Mark Olfert, David M. Smith, Emidio E Pistilli, Jefferson C Frisbee, Paul D. Chantler

Exp Physiol. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Exp Physiol. 2018 Apr 1; 103(4): 590–603. Published online 2018 Feb 28. doi: 10.1113/EP086818

PMCID:: PMC5878714

Abstract Article PDF–1.4M

Select item 55630033.

Age exacerbates microglial activation, oxidative stress, inflammatory and NOX2 gene expression, and delays functional recovery in a middle-aged rodent model of spinal cord injury

Ramona E. von Leden, Guzal Khayrullina, Kasey E. Moritz, Kimberly R. Byrnes

J Neuroinflammation. 2017; 14: 161. Published online 2017 Aug 18. doi: 10.1186/s12974-017-0933-3

PMCID:: PMC5563003

Abstract Article PDF–1.4M

Select item 53555214.

Early Loss of Blood-Brain Barrier Integrity Precedes NOX2 Elevation in the Prefrontal Cortex of an Animal Model of Psychosis

Stefania Schiavone, Emanuela Mhillaj, Margherita Neri, Maria Grazia Morgese, Paolo Tucci, Maria Bove, Mario Valentino, Giuseppe Di Giovanni, Cristoforo Pomara, Emanuela Turillazzi, Luigia Trabace, Vincenzo Cuomo

Mol Neurobiol. 2017; 54(3): 2031–2044. Published online 2016 Feb 24. doi: 10.1007/s12035-016-9791-8

PMCID:: PMC5355521

Abstract Article PDF–1.8M

Select item 51287945.

Rhein and rhubarb similarly protect the blood-brain barrier after experimental traumatic brain injury via gp91^phox subunit of NADPH oxidase/ROS/ERK/MMP-9 signaling pathway

Yang Wang, Xuegong Fan, Tao Tang, Rong Fan, Chunhu Zhang, Zebing Huang, Weijun Peng, Pingping Gan, Xingui Xiong, Wei Huang, Xi Huang

Sci Rep. 2016; 6: 37098. Published online 2016 Nov 30. doi: 10.1038/srep37098

PMCID:: PMC5128794

Abstract Article PDF–1.8M

Select item 49749136.

NOX2 Antisense Attenuates Hypoxia-Induced Oxidative Stress and Apoptosis in Cardiomyocyte

Bo Yu, Fanbo Meng, Yushuang Yang, Dongna Liu, Kaiyao Shi

Int J Med Sci. 2016; 13(8): 646–652. Published online 2016 Jul 27. doi: 10.7150/ijms.15177

PMCID:: PMC4974913

Abstract Article PDF–1.0M

Select item 42694547.

Intestinal NADPH Oxidase 2 Activity Increases in a Neonatal Rat Model of Necrotizing Enterocolitis

Scott R. Welak, Rebecca M. Rentea, Ru-Jeng Teng, Nathan Heinzerling, Ben Biesterveld, Jennifer L. Liedel, Kirkwood A. Pritchard, Jr, Katherine M. Fredrich, David M. Gourlay

PLoS One. 2014; 9(12): e115317. Published online 2014 Dec 17. doi: 10.1371/journal.pone.0115317

PMCID:: PMC4269454

Abstract Article PDF–615K

Select item 36331628.

X-ROS signalling is enhanced and graded by cyclic cardiomyocyte stretch

Benjamin L. Prosser, Christopher W. Ward, W. Jonathan Lederer

Cardiovasc Res. 2013 May 1; 98(2): 307–314. Published online 2013 Mar 21. doi: 10.1093/cvr/cvt066

PMCID:: PMC3633162

Abstract Article PDF–895K

Select item 34400219.

AAV-Based RNAi Silencing of NADPH Oxidase gp91^phox Attenuates Cold-Induced Cardiovascular Dysfunction

Xiuqing Wang, Lucille Skelley, Bo Wang, Ayesha Mejia, Val Sapozhnikov, Zhongjie Sun

Hum Gene Ther. 2012 Sep; 23(9): 1016–1026. Published online 2012 Jun 26. doi: 10.1089/hum.2012.078

PMCID:: PMC3440021

Abstract Article PDF–1.6M

Select item 340931710.

Nox2 is a mediator of chronic CsA nephrotoxicity

Arjang Djamali, Shannon Reese, Omeed Hafez, Aparna Vidyasagar, Lynn Jacobson, William Swain, Christine Kolehmainen, Lingjin Huang, Nancy A. Wilson, Jose R. Torrealba

Am J Transplant. Author manuscript; available in PMC 2013 Aug 1.

Published in final edited form as: Am J Transplant. 2012 Aug; 12(8): 1997–2007. Published online 2012 May 8. doi: 10.1111/j.1600-6143.2012.04081.x

PMCID:: PMC3409317

Abstract Article PDF–3.6M

Select item 303203511.

Cadmium induction of reactive oxygen species activates mTOR pathway, leading to neuronal cell death

Long Chen, Baoshan Xu, Lei Liu, Yan Luo, Hongyu Zhou, Wenxing Chen, Tao Shen, Xiuzhen Han, Christopher D. Kontos, Shile Huang

Free Radic Biol Med. Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: Free Radic Biol Med. 2011 Mar 1; 50(5): 624–632. Published online 2010 Dec 30. doi: 10.1016/j.freeradbiomed.2010.12.032

PMCID:: PMC3032035

Abstract Article PDF–1.1M

Select item 295516312.

Local arterial nanoparticle delivery of siRNA for NOX2 knockdown to prevent restenosis in an atherosclerotic rat model

Jian-ming Li, Peter E. Newburger, Matthew Gounis, Phong Dargon, Xueqing Zhang, Louis M. Messina

Gene Ther. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Gene Ther. 2010 Oct; 17(10): 1279–1287. Published online 2010 May 20. doi: 10.1038/gt.2010.69

PMCID:: PMC2955163

Abstract Article PDF–1.3M

Select item 287787813.

Involvement of NADPH oxidase in age-associated cardiac remodeling

Mingyi Wang, Jing Zhang, Simon J. Walker, Rafal Dworakowski, Edward G. Lakatta, Ajay M. Shah

J Mol Cell Cardiol. 2010 Apr; 48(4): 765–772. doi: 10.1016/j.yjmcc.2010.01.006

PMCID:: PMC2877878

Abstract Article

Select item 190579014.

Point mutations in the promoter region of the CYBB gene leading to mild chronic granulomatous disease

R S Weening, M De Boer, T W Kuijpers, V M E Neefjes, W W M Hack, D Roos

Clin Exp Immunol. 2000 Dec; 122(3): 410–417. doi: 10.1046/j.1365-2249.2000.01405.x

PMCID:: PMC1905790

Abstract Article PDF–138K

Select item 29519915.

Mutations in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558.

P E Newburger, D G Skalnik, P J Hopkins, E A Eklund, J T Curnutte

J Clin Invest. 1994 Sep; 94(3): 1205–1211. doi: 10.1172/JCI117437

PMCID:: PMC295199

Summary Page Browse PDF–1.6M

Select item 1105612316.

Gestational Hypoxia Impaired Endothelial Nitric Oxide Synthesis Via miR‐155‐5p/NADPH Oxidase/Reactive Oxygen Species Axis in Male Offspring Vessels

Meng Zhao, Jiahui Lei, Fengying Deng, Chenxuan Zhao, Ting Xu, Bingyu Ji, Mengyu Fu, Xietong Wang, Miao Sun, Meihua Zhang, Qinqin Gao

J Am Heart Assoc. 2024 Feb 6; 13(3): e032079. Published online 2024 Jan 19. doi: 10.1161/JAHA.123.032079

PMCID:: PMC11056123

Abstract Article PDF–13M

Select item 769804617.

Nox2 Upregulation and p38α MAPK Activation in Right Ventricular Hypertrophy of Rats Exposed to Long-Term Chronic Intermittent Hypobaric Hypoxia

Eduardo Pena, Patricia Siques, Julio Brito, Silvia M. Arribas, Rainer Böger, Juliane Hannemann, Fabiola León-Velarde, M. Carmen González, M. Rosario López, Ángel Luis López de Pablo

Int J Mol Sci. 2020 Nov; 21(22): 8576. Published online 2020 Nov 13. doi: 10.3390/ijms21228576