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Select item 86348561.

A brief overview of BNIP3L/NIX receptor‐mediated mitophagy

Mija Marinković, Ivana Novak

FEBS Open Bio. 2021 Dec; 11(12): 3230–3236. Published online 2021 Oct 11. doi: 10.1002/2211-5463.13307

PMCID:: PMC8634856

Abstract Article PDF–842K

Select item 84967152.

BNIP3L/Nix-induced mitochondrial fission, mitophagy, and impaired myocyte glucose uptake are abrogated by PRKA/PKA phosphorylation

Simone C. da Silva Rosa, Matthew D. Martens, Jared T. Field, Lucas Nguyen, Stephanie M. Kereliuk, Yan Hai, Donald Chapman, William Diehl-Jones, Michel Aliani, Adrian R. West, James Thliveris, Saeid Ghavami, Christof Rampitsch, Vernon W. Dolinsky, Joseph W. Gordon

Autophagy. 2021; 17(9): 2257–2272. Published online 2020 Oct 12. doi: 10.1080/15548627.2020.1821548

PMCID:: PMC8496715

Abstract Article PDF–8.1M

Select item 82587583.

Expression and Clinical Significance of BCL2 Interacting Protein 3 Like in Multiple Myeloma

Ruolin Li, Gang Chen, Yiwu Dang, Rongquan He, Angui Liu, Jie Ma, Zhian Ling

Technol Cancer Res Treat. 2021; 20: 15330338211024551. Published online 2021 Jun 30. doi: 10.1177/15330338211024551

PMCID:: PMC8258758

Abstract Article PDF–1.9M

Select item 81432354.

Dimerization of mitophagy receptor BNIP3L/NIX is essential for recruitment of autophagic machinery

Mija Marinković, Matilda Šprung, Ivana Novak

Autophagy. 2021; 17(5): 1232–1243. Published online 2020 Apr 24. doi: 10.1080/15548627.2020.1755120

PMCID:: PMC8143235

Abstract Article PDF–2.9M

Select item 72126715.

Identification of rare and common variants in BNIP3L: a schizophrenia susceptibility gene

Juan Zhou, Chuanchuan Ma, Ke Wang, Xiuli Li, Xuemin Jian, Han Zhang, Jianmin Yuan, Jiajun Yin, Jianhua Chen, Yongyong Shi

Hum Genomics. 2020; 14: 16. Published online 2020 May 11. doi: 10.1186/s40246-020-00266-4

PMCID:: PMC7212671

Abstract Article PDF–1.6M

Select item 68011036.

Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma

Jinkyu Jung, Ying Zhang, Orieta Celiku, Wei Zhang, Hua Song, Brian J. Williams, Amber J. Giles, Jeremy N. Rich, Roger Abounader, Mark R. Gilbert, Deric M. Park

Cancer Res. Author manuscript; available in PMC 2020 Apr 15.

Published in final edited form as: Cancer Res. 2019 Oct 15; 79(20): 5218–5232. Published online 2019 Sep 5. doi: 10.1158/0008-5472.CAN-19-0198

PMCID:: PMC6801103

Abstract Article PDF–4.0M

Select item 61774787.

Molecular signalling towards mitochondrial breakdown is enhanced in skeletal muscle of patients with chronic obstructive pulmonary disease (COPD)

P. A. Leermakers, A. M. W. J. Schols, A. E. M. Kneppers, M. C. J. M. Kelders, C. C. de Theije, M. Lainscak, H. R. Gosker

Sci Rep. 2018; 8: 15007. Published online 2018 Oct 9. doi: 10.1038/s41598-018-33471-2

PMCID:: PMC6177478

Abstract Article PDF–2.3M

Select item 112547298.

CTCF and BORIS-mediated autophagy regulation via alternative splicing of BNIP3L in breast cancer

Anchala Pandey, Parik Kakani, Sanjeev Shukla

J Biol Chem. 2024 Jul; 300(7): 107416. Published online 2024 May 27. doi: 10.1016/j.jbc.2024.107416

PMCID:: PMC11254729

Abstract Article PDF–3.2M

Select item 103083579.

FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels

Hannah Elcocks, Ailbhe J Brazel, Katy R McCarron, Manuel Kaulich, Koraljka Husnjak, Heather Mortiboys, Michael J Clague, Sylvie Urbé

EMBO J. 2023 Jul; 42(13): e112799. Published online 2023 Apr 27. doi: 10.15252/embj.2022112799

PMCID:: PMC10308357

Abstract Article PDF–4.0M

Select item 991387810.

Mitophagy Effects of Protodioscin on Human Osteosarcoma Cells by Inhibition of p38MAPK Targeting NIX/LC3 Axis

Chien-Feng Huang, Yi-Hsien Hsieh, Shun-Fa Yang, Chao-Hung Kuo, Pei-Han Wang, Chung-Jung Liu, Renn-Chia Lin

Cells. 2023 Feb; 12(3): 395. Published online 2023 Jan 21. doi: 10.3390/cells12030395

PMCID:: PMC9913878

Abstract Article PDF–10M

Select item 750876911.

Hypoxia regulates the degradation of non-nuclear organelles during lens differentiation through activation of HIF1a.

Lisa Brennan, Joshua Disatham, Marc Kantorow

Exp Eye Res. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: Exp Eye Res. 2020 Sep; 198: 108129. Published online 2020 Jul 3. doi: 10.1016/j.exer.2020.108129

PMCID:: PMC7508769

Abstract Article PDF–1.8M

Select item 672654012.

Oncogenic Kras induces Nix-mediated mitophagy to promote pancreatic cancer

Timothy J. Humpton, Brinda Alagesan, Gina M. DeNicola, Dan Lu, Georgi N. Yordanov, Carl S. Leonhardt, Melissa A. Yao, Priya Alagesan, Maya N. Zaatari, Youngkyu Park, Jeremy N. Skepper, Kay F. Macleod, Pedro A. Perez-Mancera, Michael P. Murphy, Gerard I. Evan, Karen H. Vousden, David A. Tuveson

Cancer Discov. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: Cancer Discov. 2019 Sep; 9(9): 1268–1287. Published online 2019 Jul 1. doi: 10.1158/2159-8290.CD-18-1409

PMCID:: PMC6726540

Abstract Article PDF–2.6M

Select item 543063313.

Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins

Vladimir V. Rogov, Hironori Suzuki, Mija Marinković, Verena Lang, Ryuichi Kato, Masato Kawasaki, Maja Buljubašić, Matilda Šprung, Natalia Rogova, Soichi Wakatsuki, Anne Hamacher-Brady, Volker Dötsch, Ivan Dikic, Nathan R. Brady, Ivana Novak

Sci Rep. 2017; 7: 1131. Published online 2017 Apr 25. doi: 10.1038/s41598-017-01258-6

PMCID:: PMC5430633

Abstract Article PDF–4.7M

Select item 481145714.

Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy

Nastasia Wilfinger, Shane Austin, Barbara Scheiber-Mojdehkar, Walter Berger, Siegfried Reipert, Monika Praschberger, Jakob Paur, Robert Trondl, Bernhard K. Keppler, Christoph C. Zielinski, Karin Nowikovsky

Oncotarget. 2016 Jan 12; 7(2): 1242–1261. Published online 2015 Oct 26. doi: 10.18632/oncotarget.6233

PMCID:: PMC4811457

Abstract Article PDF–1.8M

Select item 344044015.

Nix Protein Positively Regulates NF-κB Activation in Gliomas

Yuntao Lu, Leyu Wang, Minyi He, Wenhua Huang, Hong Li, Yongkui Wang, Jiming Kong, Songtao Qi, Jun Ouyang, Xiaozhong Qiu

PLoS One. 2012; 7(9): e44559. Published online 2012 Sep 12. doi: 10.1371/journal.pone.0044559

PMCID:: PMC3440440

Abstract Article PDF–566K

Select item 248157616.

Homozygous Deletions and Recurrent Amplifications Implicate New Genes Involved in Prostate Cancer

Wennuan Liu, Chunmei Carol Xie, Yi Zhu, Tao Li, Jishan Sun, Yu Cheng, Charles M Ewing, Sue Dalrymple, Aubrey R Turner, Jielin Sun, John T Isaacs, Bao-Li Chang, Siqun Lilly Zheng, William B Isaacs, Jianfeng Xu

Neoplasia. 2008 Aug; 10(8): 897–907. doi: 10.1593/neo.08428

PMCID:: PMC2481576

Abstract Article PDF–6.4M

Select item 996033017.

The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy

Mehmet Oguz Gok, Olivia M. Connor, Xun Wang, Cameron J. Menezes, Claire B. Llamas, Prashant Mishra, Jonathan R. Friedman

J Cell Biol. 2023 Apr 3; 222(4): e202204021. Published online 2023 Feb 16. doi: 10.1083/jcb.202204021

PMCID:: PMC9960330

Abstract Article PDF–8.1M

Select item 862813918.

SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy

Xingyu Li, Peili Hou, Wenqing Ma, Xuefeng Wang, Hongmei Wang, Zhangping Yu, Huasong Chang, Tiecheng Wang, Song Jin, Xue Wang, Wenqi Wang, Yudong Zhao, Yong Zhao, Chunqing Xu, Xiaomei Ma, Yuwei Gao, Hongbin He

Cell Mol Immunol. 2022 Jan; 19(1): 67–78. Published online 2021 Nov 29. doi: 10.1038/s41423-021-00807-4

Correction in:: Cell Mol Immunol. 2023 Jun; 20(6): 686.

PMCID:: PMC8628139

Abstract Article PDF–2.0M

Select item 639144819.

Mieap-induced accumulation of lysosomes within mitochondria (MALM) regulates gastric cancer cell invasion under hypoxia by suppressing reactive oxygen species accumulation

Keiichiro Okuyama, Yoshihiko Kitajima, Noriyuki Egawa, Hiroshi Kitagawa, Kotaro Ito, Shinichi Aishima, Kazuyoshi Yanagihara, Tomokazu Tanaka, Hirokazu Noshiro

Sci Rep. 2019; 9: 2822. Published online 2019 Feb 26. doi: 10.1038/s41598-019-39563-x

PMCID:: PMC6391448

Abstract Article PDF–2.2M

Select item 534507320.

Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson’s disease

Brianada Koentjoro, Jin-Sung Park, Carolyn M. Sue

Sci Rep. 2017; 7: 44373. Published online 2017 Mar 10. doi: 10.1038/srep44373

PMCID:: PMC5345073

Abstract Article PDF–1.5M

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PMC Links for Gene (Select 665) (58)
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Homo sapiens zinc finger protein 876, pseudogene (ZNF876P), non-coding RNA
Homo sapiens zinc finger protein 876, pseudogene (ZNF876P), non-coding RNA
gi|226529339|ref|NR_027481.1|

Nucleotide

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