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Select item 108733661.

DNA binding redistributes activation domain ensemble and accessibility in pioneer factor Sox2

Sveinn Bjarnason, Jordan A. P. McIvor, Andreas Prestel, Kinga S. Demény, Jakob T. Bullerjahn, Birthe B. Kragelund, Davide Mercadante, Pétur O. Heidarsson

Nat Commun. 2024; 15: 1445. Published online 2024 Feb 16. doi: 10.1038/s41467-024-45847-2

PMCID:: PMC10873366

Abstract Article PDF–3.0M

Select item 108547812.

SOX2 Expression Does Not Guarantee Cancer Stem Cell-like Characteristics in Lung Adenocarcinoma

Seung-Hyun Bae, Kyung Yong Lee, Suji Han, Chul Won Yun, ChanHyeok Park, Hyonchol Jang

Cells. 2024 Feb; 13(3): 216. Published online 2024 Jan 24. doi: 10.3390/cells13030216

PMCID:: PMC10854781

Abstract Article PDF–3.8M

Select item 107210993.

SOX2 promotes a cancer stem cell-like phenotype and local spreading in oral squamous cell carcinoma

Alessandro Sacco, Anna Martina Battaglia, Gianluca Santamaria, Caterina Buffone, Selene Barone, Anna Procopio, Anna Maria Lavecchia, Ilenia Aversa, Emanuele Giorgio, Lavinia Petriaggi, Maria Giulia Cristofaro, Flavia Biamonte, Amerigo Giudice

PLoS One. 2023; 18(12): e0293475. Published online 2023 Dec 14. doi: 10.1371/journal.pone.0293475

PMCID:: PMC10721099

Abstract Article PDF–1.8M

Select item 107115504.

Molecular basis for SOX2-dependent regulation of super-enhancer activity

Wanki Yoo, Yi Wei Song, Jihyun Kim, Jihye Ahn, Jaehoon Kim, Yongdae Shin, Je-Kyung Ryu, Kyeong Kyu Kim

Nucleic Acids Res. 2023 Dec 11; 51(22): 11999–12019. Published online 2023 Nov 1. doi: 10.1093/nar/gkad908

PMCID:: PMC10711550

Abstract Article PDF–2.5M

Select item 106558185.

iPSCs derived from esophageal atresia patients reveal SOX2 dysregulation at the anterior foregut stage

Suleen Raad, Anu David, Melanie Sagniez, Bastien Paré, Zakaria Orfi, Nicolas A. Dumont, Martin A. Smith, Christophe Faure

Dis Model Mech. 2022 Nov 1; 15(11): dmm049541. Published online 2022 Nov 28. doi: 10.1242/dmm.049541

PMCID:: PMC10655818

Abstract Article

Select item 101981486.

SOX2 Promotes Radioresistance in Non-small Cell Lung Cancer by Regulating Tumor Cells Dedifferentiation

Shennan Wang, Zhou Li, Piao Li, Lingling Li, Yu Liu, Yanqi Feng, Ruichao Li, Shu Xia

Int J Med Sci. 2023; 20(6): 781–796. Published online 2023 Apr 29. doi: 10.7150/ijms.75315

PMCID:: PMC10198148

Abstract Article PDF–6.3M

Select item 100222777.

SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis

Abdel Jelil Njouendou, Tibor Szarvas, Arnol Auvaker Zebaze Tiofack, Rovaldo Nguims Kenfack, Pamela Derliche Tonouo, Sidonie Noa Ananga, Esther H. M. Dina Bell, Gustave Simo, Jörg D. Hoheisel, Jens T. Siveke, Smiths S. Lueong

Mol Cancer. 2023; 22: 52. Published online 2023 Mar 17. doi: 10.1186/s12943-023-01734-w

PMCID:: PMC10022277

Abstract Article PDF–5.4M

Select item 98317298.

SOX2-high cancer cells exhibit an aggressive phenotype, with increases in stemness, proliferation and invasion, as well as higher metabolic activity and ATP production

Marta Mauro-Lizcano, Federica Sotgia, Michael P. Lisanti

Aging (Albany NY) 2022 Dec 31; 14(24): 9877–9889. Published online 2022 Dec 22. doi: 10.18632/aging.204452

PMCID:: PMC9831729

Abstract Article PDF–1.0M

Select item 98151019.

Prognostic implication of SOX2 expression in small intestinal adenocarcinoma

Jeong Won Kim, Joon-Yong Chung, Kris Ylaya, Yoonho Park, Sun-Young Jun, Seung-Mo Hong, Stephen M. Hewitt

Virchows Arch. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Virchows Arch. 2021 Jun; 478(6): 1049–1060. Published online 2020 Oct 25. doi: 10.1007/s00428-020-02946-x

PMCID:: PMC9815101

Abstract Article PDF–1.5M

Select item 972681310.

SOX2 expression in the pathogenesis of premalignant lesions of the uterine cervix: its histo-topographical distribution distinguishes between low- and high-grade CIN

Jobran M. Moshi, Monique Ummelen, Jos L. V. Broers, Frank Smedts, Koen K. Van de Vijver, Jack P. M. Cleutjens, Rogier J. N. T. M. Litjens, Frans C. S. Ramaekers, Anton H. N. Hopman

Histochem Cell Biol. 2022; 158(6): 545–559. Published online 2022 Aug 9. doi: 10.1007/s00418-022-02145-6

PMCID:: PMC9726813

Abstract Article PDF–4.9M

Select item 957025211.

Dissecting Stemness in Aggressive Intracranial Meningiomas: Prognostic Role of SOX2 Expression

Rina Di Bonaventura, Maurizio Martini, Tonia Cenci, Valerio Maria Caccavella, Valeria Barresi, Marco Gessi, Alessio Albanese, Liverana Lauretti, Roberto Pallini, Quintino Giorgio D′Alessandris, Alessandro Olivi

Int J Mol Sci. 2022 Oct; 23(19): 11690. Published online 2022 Oct 2. doi: 10.3390/ijms231911690

PMCID:: PMC9570252

Abstract Article PDF–2.4M

Select item 947899012.

SOX2 regulates paclitaxel resistance of A549 non-small cell lung cancer cells via promoting transcription of ClC-3

Youwei Huang, Xiangyu Wang, Rendong Hu, Guopeng Pan, Xi Lin

Oncol Rep. 2022 Oct; 48(4): 181. Published online 2022 Sep 6. doi: 10.3892/or.2022.8396

PMCID:: PMC9478990

Abstract Article PDF–1.5M

Select item 931759213.

Evaluation of the Impact of Pregnancy-Associated Factors on the Quality of Wharton’s Jelly-Derived Stem Cells Using SOX2 Gene Expression as a Marker

Paulina Gil-Kulik, Małgorzata Świstowska, Arkadiusz Krzyżanowski, Alicja Petniak, Anna Kwaśniewska, Bartosz J. Płachno, Dariusz Galkowski, Anna Bogucka-Kocka, Janusz Kocki

Int J Mol Sci. 2022 Jul; 23(14): 7630. Published online 2022 Jul 10. doi: 10.3390/ijms23147630

PMCID:: PMC9317592

Abstract Article PDF–1.5M

Select item 916987014.

Review of 37 patients with SOX2 pathogenic variants collected by the Anophthalmia/Microphthalmia Clinical Registry and DNA research study

Louise Amlie-Wolf, Tanya Bardakjian, Sarina M. Kopinsky, Linda M. Reis, Elena V. Semina, Adele Schneider

Am J Med Genet A. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Am J Med Genet A. 2022 Jan; 188(1): 187–198. Published online 2021 Sep 25. doi: 10.1002/ajmg.a.62518

PMCID:: PMC9169870

Abstract Article PDF–313K

Select item 914401715.

SOX2 Is a Univocal Marker for Human Oral Mucosa Epithelium Useful in Post-COMET Patient Characterization

Eustachio Attico, Giulia Galaverni, Elisa Bianchi, Lorena Losi, Rossella Manfredini, Alessandro Lambiase, Paolo Rama, Graziella Pellegrini

Int J Mol Sci. 2022 May; 23(10): 5785. Published online 2022 May 21. doi: 10.3390/ijms23105785

PMCID:: PMC9144017

Abstract Article PDF–1.9M

Select item 909310616.

Movements of Ancient Human Endogenous Retroviruses Detected in SOX2-Expressing Cells

Kazuaki Monde, Yorifumi Satou, Mizuki Goto, Yoshikazu Uchiyama, Jumpei Ito, Taku Kaitsuka, Hiromi Terasawa, Nami Monde, Shinya Yamaga, Tomoya Matsusako, Fan-Yan Wei, Ituro Inoue, Kazuhito Tomizawa, Akira Ono, Takumi Era, Tomohiro Sawa, Yosuke Maeda

J Virol. 2022 May; 96(9): e00356-22. Published online 2022 Apr 14. doi: 10.1128/jvi.00356-22