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Select item 107170421.

SPOCK1, as a potential prognostic and therapeutic biomarker for lung adenocarcinoma, is associated with epithelial-mesenchymal transition and immune evasion

Yafeng Liu, Tao Han, Jing Wu, Jiawei Zhou, Jianqiang Guo, Rui Miao, Zhi Xu, Yingru Xing, Ying Bai, Dong Hu

J Transl Med. 2023; 21: 909. Published online 2023 Dec 12. doi: 10.1186/s12967-023-04616-3

PMCID:: PMC10717042

Abstract Article PDF–21M

Select item 99137952.

Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition

Yung-Wei Lin, Yu-Ching Wen, Chi-Hao Hsiao, Feng-Ru Lai, Shun-Fa Yang, Yi-Chieh Yang, Kuo-Hao Ho, Feng-Koo Hsieh, Michael Hsiao, Wei-Jiunn Lee, Ming-Hsien Chien

Cells. 2023 Feb; 12(3): 352. Published online 2023 Jan 17. doi: 10.3390/cells12030352

PMCID:: PMC9913795

Abstract Article PDF–3.7M

Select item 82368073.

Multiomic analysis of the function of SPOCK1 across cancers: an integrated bioinformatics approach

Jie Han, Yihui Rong, Xudong Gao

J Int Med Res. 2021 Jun; 49(6): 0300060520962659. Published online 2021 Jun 22. doi: 10.1177/0300060520962659

PMCID:: PMC8236807

Abstract Article PDF–1.5M

Select item 78386864.

Knockdown of SPOCK1 Inhibits the Proliferation and Invasion in Colorectal Cancer Cells by Suppressing the PI3K/Akt Pathway

Ping Zhao, Hai-Tao Guan, Zhi-Jun Dai, Yu-Guang Ma, Xiao-Xu Liu, Xi-Jing Wang

Oncol Res. 2016; 24(6): 437–445. Published online 2016 Oct 27. doi: 10.3727/096504016X14685034103554

PMCID:: PMC7838686

Abstract Article PDF–7.6M

Select item 77632185.

The Central Region of Testican-2 Forms a Compact Core and Promotes Cell Migration

Anja Krajnc, Aljaž Gaber, Brigita Lenarčič, Miha Pavšič

Int J Mol Sci. 2020 Dec; 21(24): 9413. Published online 2020 Dec 10. doi: 10.3390/ijms21249413

PMCID:: PMC7763218

Abstract Article PDF–8.1M

Select item 55377006.

Stromal SPOCK1 supports invasive pancreatic cancer growth

Veronique L. Veenstra, Helene Damhofer, Cynthia Waasdorp, Anne Steins, Hemant M. Kocher, Jan P. Medema, Hanneke W. van Laarhoven, Maarten F Bijlsma

Mol Oncol. 2017 Aug; 11(8): 1050–1064. Published online 2017 Jun 5. doi: 10.1002/1878-0261.12073

PMCID:: PMC5537700

Abstract Article PDF–1.8M

Select item 50231877.

SPOCK1 Is a Novel Transforming Growth Factor-β–Induced Myoepithelial Marker That Enhances Invasion and Correlates with Poor Prognosis in Breast Cancer

Li-Ching Fan, Yung-Ming Jeng, Yueh-Tong Lu, Huang-Chun Lien

PLoS One. 2016; 11(9): e0162933. Published online 2016 Sep 14. doi: 10.1371/journal.pone.0162933

PMCID:: PMC5023187

Abstract Article PDF–1.8M

Select item 49583688.

SPOCK1 promotes tumor growth and metastasis in human prostate cancer

Qi Chen, Yuan-ting Yao, Huan Xu, Yan-bo Chen, Meng Gu, Zhi-kang Cai, Zhong Wang

Drug Des Devel Ther. 2016; 10: 2311–2321. Published online 2016 Jul 18. doi: 10.2147/DDDT.S91321

PMCID:: PMC4958368

Abstract Article PDF–2.7M

Select item 43208429.

SPOCK1 as a potential cancer prognostic marker promotes the proliferation and metastasis of gallbladder cancer cells by activating the PI3K/AKT pathway

Yi-Jun Shu, Hao Weng, Yuan-Yuan Ye, Yun-Ping Hu, Run-Fa Bao, Yang Cao, Xu-An Wang, Fei Zhang, Shan-Shan Xiang, Huai-Feng Li, Xiang-Song Wu, Mao-Lan Li, Lin Jiang, Wei Lu, Bao-San Han, Zhi-Gang Jie, Ying-Bin Liu

Mol Cancer. 2015; 14(1): 12. Published online 2015 Jan 27. doi: 10.1186/s12943-014-0276-y

PMCID:: PMC4320842

Abstract Article PDF–3.4M

Select item 265210710.

Genome-Wide Association Analyses Identify SPOCK as a Key Novel Gene Underlying Age at Menarche

Yao-Zhong Liu, Yan-Fang Guo, Liang Wang, Li-Jun Tan, Xiao-Gang Liu, Yu-Fang Pei, Han Yan, Dong-Hai Xiong, Fei-Yan Deng, Na Yu, Yin-Ping Zhang, Lei Zhang, Shu-Feng Lei, Xiang-Ding Chen, Hong-Bin Liu, Xue-Zhen Zhu, Shawn Levy, Christopher J. Papasian, Betty M. Drees, James J. Hamilton, Robert R. Recker, Hong-Wen Deng

PLoS Genet. 2009 Mar; 5(3): e1000420. Published online 2009 Mar 13. doi: 10.1371/journal.pgen.1000420

PMCID:: PMC2652107

Abstract Article PDF–752K

Select item 982658111.

SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor immune infiltrates in colorectal cancer

Caiqin Gan, Mengting Li, Yuanyuan Lu, Ganjing Peng, Wenjie Li, Haizhou Wang, Yanan Peng, Qian Hu, Wanhui Wei, Fan Wang, Lan Liu, Qiu Zhao

BMC Gastroenterol. 2023; 23: 4. Published online 2023 Jan 7. doi: 10.1186/s12876-022-02621-2

PMCID:: PMC9826581

Abstract Article PDF–11M

Select item 783506112.

SPOCK1/SIX1axis promotes breast cancer progression by activating AKT/mTOR signaling

Ming Xu, Xianglan Zhang, Songnan Zhang, Junjie Piao, Yang Yang, Xinyue Wang, Zhenhua Lin

Aging (Albany NY) 2021 Jan 15; 13(1): 1032–1050. Published online 2020 Dec 3. doi: 10.18632/aging.202231

PMCID:: PMC7835061

Abstract Article PDF–3.7M

Select item 730001113.

SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth

Rehab Alshargabi, Tomomi Sano, Akiko Yamashita, Aiko Takano, Taiki Sanada, Misaki Iwashita, Takanori Shinjo, Takao Fukuda, Terukazu Sanui, Shosei Kishida, Fusanori Nishimura

Sci Rep. 2020; 10: 9785. Published online 2020 Jun 17. doi: 10.1038/s41598-020-66660-z

PMCID:: PMC7300011

Abstract Article PDF–6.5M

Select item 578386714.

SPOCK1 promotes the invasion and metastasis of gastric cancer through Slug‐induced epithelial‐mesenchymal transition

Dehu Chen, Haihua Zhou, Guiyuan Liu, Yinghai Zhao, Gan Cao, Qinghong Liu

J Cell Mol Med. 2018 Feb; 22(2): 797–807. Published online 2017 Sep 22. doi: 10.1111/jcmm.13357

PMCID:: PMC5783867

Abstract Article PDF–1.1M

Select item 524852615.

EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth

Naiara Perurena, Carolina Zandueta, Susana Martínez-Canarias, Haritz Moreno, Silvestre Vicent, Ana S. Almeida, Elisabet Guruceaga, Roger R. Gomis, Marta Santisteban, Mikala Egeblad, José Hermida, Fernando Lecanda

J Hematol Oncol. 2017; 10: 23. Published online 2017 Jan 19. doi: 10.1186/s13045-017-0399-x

PMCID:: PMC5248526

Abstract Article PDF–2.7M

Select item 886359016.

Expression and Potential Prognostic Value of SOX9, MCL-1 and SPOCK1 in Gastric Adenocarcinoma

Wenyi Luo, Teddy S. Nagaria, Hongxia Sun, Junsheng Ma, Jamie L. Lombardo, Roland Bassett, Austin C. Cao, Dongfeng Tan

Pathol Oncol Res. 2022; 28: 1610293. Published online 2022 Feb 9. doi: 10.3389/pore.2022.1610293

PMCID:: PMC8863590

Abstract Article PDF–1.5M

Select item 829178817.

Long non-coding RNA TTN antisense RNA 1 facilitates hepatocellular carcinoma progression via regulating miR-139-5p/SPOCK1 axis

Xinghao Zhu, Shiqing Jiang, Zongyao Wu, Tonghua Liu, Wei Zhang, Lili Wu, Lijun Xu, Mingliang Shao

Bioengineered. 2021; 12(1): 578–588. Published online 2021 Feb 8. doi: 10.1080/21655979.2021.1882133

PMCID:: PMC8291788

Abstract Article PDF–3.0M

Select item 643365718.

MiR‐139‐5p, miR‐940 and miR‐193a‐5p inhibit the growth of hepatocellular carcinoma by targeting SPOCK1

Peng Li, Zhiwei Xiao, Jiajun Luo, Yaojun Zhang, Lizhu Lin

J Cell Mol Med. 2019 Apr; 23(4): 2475–2488. Published online 2019 Feb 1. doi: 10.1111/jcmm.14121

PMCID:: PMC6433657

Abstract Article PDF–3.1M

Select item 372767519.

A Genome-Wide Association Study (GWAS) for Bronchopulmonary Dysplasia

Hui Wang, Krystal R. St. Julien, David K. Stevenson, Thomas J. Hoffmann, John S. Witte, Laura C. Lazzeroni, Mark A. Krasnow, Cecele C. Quaintance, John W. Oehlert, Laura L. Jelliffe-Pawlowski, Jeffrey B. Gould, Gary M. Shaw, Hugh M. O’Brodovich

Pediatrics. 2013 Aug; 132(2): 290–297. doi: 10.1542/peds.2013-0533

PMCID:: PMC3727675

Abstract Article PDF–844K

Select item 752370620.

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani

Oncogene. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9