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Select item 107578911.

Spatiotemporal expression and coexpression patterns of SRPK1 in the human brain: A neurodevelopmental perspective

Jing‐jing Wang, Sagor Kumar Roy, Yu‐ming Xu

Brain Behav. 2024 Jan; 14(1): e3341. Published online 2023 Dec 31. doi: 10.1002/brb3.3341

PMCID:: PMC10757891

Abstract Article PDF–1.2M

Select item 100795352.

Serine-arginine protein kinase 1 (SRPK1) promotes EGFR-TKI resistance by enhancing GSK3β Ser9 autophosphorylation independent of its kinase activity in non-small-cell lung cancer

Jing-Qiang Huang, Ling-Xin Duan, Qiu-Yu Liu, He-Feng Li, Ao-Ping Hu, Jun-Wei Song, Chuxuan Lin, Bingsheng Huang, Da Yao, Bin Peng, Yehong Sun, Yuxin Wen, Lin Yang, Xingzhi Xu, Li-Yun Gong

Oncogene. 2023; 42(15): 1233–1246. Published online 2023 Mar 3. doi: 10.1038/s41388-023-02645-2

PMCID:: PMC10079535

Abstract Article PDF–6.6M

Select item 96094663.

Inhibition of SRPK1, a key splicing regulator, exhibits antitumor and chemotherapeutic-sensitizing effects on extranodal NK/T-cell lymphoma cells

Cuiying He, Beichen Liu, Huan-You Wang, Lili Wu, Guimin Zhao, Chen Huang, Yueping Liu, Baoen Shan, Lihong Liu

BMC Cancer. 2022; 22: 1100. Published online 2022 Oct 27. doi: 10.1186/s12885-022-10158-6

PMCID:: PMC9609466

Abstract Article PDF–7.9M

Select item 89737694.

Increased expression of SRPK1 (serine/arginine-rich protein-specific kinase 1) is associated with progression and unfavorable prognosis in cervical squamous cell carcinoma

Zhanfei Dong, Xuezhi Chang, Li Xie, Yina Wang, Youxiang Hou

Bioengineered. 2022; 13(3): 6100–6112. Published online 2022 Feb 22. doi: 10.1080/21655979.2022.2034705

PMCID:: PMC8973769

Abstract Article PDF–3.2M

Select item 80654625.

Nuclear Translocation of SRPKs Is Associated with 5-FU and Cisplatin Sensitivity in HeLa and T24 Cells

Ioanna Sigala, Maria Koutroumani, Anastasia Koukiali, Thomas Giannakouros, Eleni Nikolakaki

Cells. 2021 Apr; 10(4): 759. Published online 2021 Mar 30. doi: 10.3390/cells10040759

PMCID:: PMC8065462

Abstract Article PDF–6.2M

Select item 78412336.

Knockdown of Serine–Arginine Protein Kinase 1 Inhibits the Growth and Migration in Renal Cell Carcinoma Cells

Xingtao Han, Jinjian Yang, Zhankui Jia, Pengtao Wei, Han Zhang, Wenwei Lv, Jiantao Sun, Qingxiang Huo

Oncol Res. 2017; 25(3): 389–395. Published online 2017 Mar 13. doi: 10.3727/096504016X14743324568129

PMCID:: PMC7841233

Abstract Article PDF–7.4M

Select item 76996477.

Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates

Adriana Savastano, Alain Ibáñez de Opakua, Marija Rankovic, Markus Zweckstetter

Nat Commun. 2020; 11: 6041. Published online 2020 Nov 27. doi: 10.1038/s41467-020-19843-1

PMCID:: PMC7699647

Abstract Article PDF–2.5M

Select item 74144538.

Human papillomavirus type 16 infection activates the host serine arginine protein kinase 1 (SRPK1) – splicing factor axis

Sarah Mole, Arwa Ali A. Faizo, Hegel Hernandez-Lopez, Megan Griffiths, Andrew Stevenson, Sally Roberts, Sheila V Graham

J Gen Virol. 2020 May; 101(5): 523–532. Published online 2020 Mar 13. doi: 10.1099/jgv.0.001402

PMCID:: PMC7414453

Abstract Article PDF–2.3M

Select item 72534639.

SRPK1 acetylation modulates alternative splicing to regulate cisplatin resistance in breast cancer cells

Cheng Wang, Zhihong Zhou, Charannya Sozheesvari Subhramanyam, Qiong Cao, Zealyn Shi Lin Heng, Wen Liu, Xiangdong Fu, Qidong Hu

Commun Biol. 2020; 3: 268. Published online 2020 May 27. doi: 10.1038/s42003-020-0983-4

PMCID:: PMC7253463

Abstract Article PDF–1.8M

Select item 704269310.

Serine-Arginine Protein Kinase 1 Regulates Ebola Virus Transcription

Yuki Takamatsu, Verena Krähling, Larissa Kolesnikova, Sandro Halwe, Clemens Lier, Stefan Baumeister, Takeshi Noda, Nadine Biedenkopf, Stephan Becker

mBio. 2020 Jan-Feb; 11(1): e02565-19. Published online 2020 Feb 25. doi: 10.1128/mBio.02565-19

PMCID:: PMC7042693

Abstract Article PDF–2.5M

Select item 701710511.

Serine-Arginine Protein Kinase 1 (SRPK1) as a Prognostic Factor and Potential Therapeutic Target in Cancer: Current Evidence and Future Perspectives

Ilias P. Nikas, Sophie C. Themistocleous, Stavroula A. Paschou, Konstantinos I. Tsamis, Han Suk Ryu

Cells. 2020 Jan; 9(1): 19. Published online 2019 Dec 19. doi: 10.3390/cells9010019

PMCID:: PMC7017105

Abstract Article PDF–2.3M

Select item 475263612.

Serine-arginine protein kinase 1 (SRPK1), a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion

Nicholas Bullock, Jonathan Potts, Andrew J Simpkin, Anthony Koupparis, Steve J Harper, Jon Oxley, Sebastian Oltean

J Clin Pathol. 2016 Feb; 69(2): 171–175. Published online 2015 Oct 23. doi: 10.1136/jclinpath-2015-203125

PMCID:: PMC4752636

Abstract Article PDF–588K

Select item 435190913.

SERINE ARGININE PROTEIN KINASE-1 (SRPK1) INHIBITION AS A POTENTIAL NOVEL TARGETED THERAPEUTIC STRATEGY IN PROSTATE CANCER

Athina Mavrou, Karen Brakspear, Maryam Hamdollah-Zadeh, Gopinath Damodaran, Roya Babaei-Jadidi, Jon Oxley, David A Gillatt, Michael R Ladomery, Steven J Harper, David O Bates, Sebastian Oltean

Oncogene. Author manuscript; available in PMC 2016 Feb 13.

Published in final edited form as: Oncogene. 2015 Aug 13; 34(33): 4311–4319. Published online 2014 Nov 10. doi: 10.1038/onc.2014.360

PMCID:: PMC4351909

Abstract Article PDF–2.1M

Select item 424892514.

Human Papillomavirus Type 1 E1^E4 Protein Is a Potent Inhibitor of the Serine-Arginine (SR) Protein Kinase SRPK1 and Inhibits Phosphorylation of Host SR Proteins and of the Viral Transcription and Replication Regulator E2

Emma L. Prescott, Claire L. Brimacombe, Margaret Hartley, Ian Bell, Sheila Graham, Sally Roberts

J Virol. 2014 Nov; 88(21): 12599–12611. doi: 10.1128/JVI.02029-14

PMCID:: PMC4248925

Abstract Article PDF–1.9M

Select item 410817815.

Recruiting a Silent Partner for Activation of the Protein Kinase SRPK1

Brandon E. Aubol, Joseph A. Adams

Biochemistry. 2014 Jul 22; 53(28): 4625–4634. Published online 2014 Jul 1. doi: 10.1021/bi500483m

PMCID:: PMC4108178

Abstract Article PDF–2.1M

Select item 386572216.

Splicing Kinase SRPK1 Conforms to the Landscape of Its SR Protein Substrate

Brandon E. Aubol, Michael Jamros, Maria L. McGlone, Joseph A. Adams

Biochemistry. Author manuscript; available in PMC 2014 Oct 29.

Published in final edited form as: Biochemistry. 2013 Oct 29; 52(43): 10.1021/bi4010864. Published online 2013 Oct 15. doi: 10.1021/bi4010864

PMCID:: PMC3865722

Abstract Article PDF–2.9M

Select item 315361117.

Applying the Brakes to Multi-Site SR Protein Phosphorylation: Substrate-Induced Effects on the Splicing Kinase SRPK1

Brandon E. Aubol, Joseph A. Adams

Biochemistry. Author manuscript; available in PMC 2012 Aug 16.

Published in final edited form as: Biochemistry. 2011 Aug 16; 50(32): 6888–6900. Published online 2011 Jul 15. doi: 10.1021/bi2007993

PMCID:: PMC3153611

Abstract Article PDF–1.3M

Select item 264865118.

Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones

Xiang-Yang Zhong, Jian-Hua Ding, Joseph A. Adams, Gourisankar Ghosh, Xiang-Dong Fu

Genes Dev. 2009 Feb 15; 23(4): 482–495. doi: 10.1101/gad.1752109

PMCID:: PMC2648651

Abstract Article PDF–1.0M

Select item 190029519.

The E1^E4 Protein of Human Papillomavirus Interacts with the Serine-Arginine-Specific Protein Kinase SRPK1

Ian Bell, Ashley Martin, Sally Roberts

J Virol. 2007 Jun; 81(11): 5437–5448. Published online 2007 Mar 14. doi: 10.1128/JVI.02609-06

PMCID:: PMC1900295

Abstract Article PDF–609K

Select item 816475020.

Genetic analysis of sinonasal undifferentiated carcinoma discovers recurrent SWI/SNF alterations and a novel PGAP3-SRPK1 fusion gene

Molly E. Heft Neal, Andrew C. Birkeland, Apurva D. Bhangale, Jingyi Zhai, Aditi Kulkarni, Susan K. Foltin, Brittany M. Jewell, Megan L. Ludwig, Lisa Pinatti, Hui Jiang, Jonathan B. McHugh, Lawence Marentette, Erin L. McKean, J. Chad Brenner

BMC Cancer. 2021; 21: 636. Published online 2021 May 29. doi: 10.1186/s12885-021-08370-x