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Select item 112101951.

TRIM21 and Fc-engineered antibodies: decoding its complex antibody binding mode with implications for viral neutralization

Johannes Reusch, Linda Elise Franken, Jakob Then, Philippe Ringler, Joachim Butzer, Thomas Juroschek, Christian Klein, Tilman Schlothauer, Laurent Larivière

Front Immunol. 2024; 15: 1401471. Published online 2024 Jun 12. doi: 10.3389/fimmu.2024.1401471

PMCID:: PMC11210195

Abstract Article PDF–7.5M

Select item 111589842.

Presence of serum tripartite motif‐containing 21 antibodies in patients with esophageal squamous cell carcinoma

Mari Kuboshima, Hideaki Shimada, Tian‐Ling Liu, Fumio Nomura, Masaki Takiguchi, Takaki Hiwasa, Takenori Ochiai

Cancer Sci. 2006 May; 97(5): 380–386. Published online 2006 Apr 10. doi: 10.1111/j.1349-7006.2006.00192.x

PMCID:: PMC11158984

Abstract Article PDF–454K

Select item 110932113.

TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway

Bo Shu, Yingxia Zhou, Guoqiong Lei, Yu Peng, Cong Ding, Zhuan Li, Chao He

Cancer Sci. 2024 May; 115(5): 1476–1491. Published online 2024 Mar 12. doi: 10.1111/cas.16134

PMCID:: PMC11093211

Abstract Article PDF–5.7M

Select item 109704744.

TRIM21 Promotes Oxidative Stress and Ferroptosis through the SQSTM1-NRF2-KEAP1 Axis to Increase the Titers of H5N1 Highly Pathogenic Avian Influenza Virus

Yifan Wei, Yongxia Gu, Ziwei Zhou, Changrong Wu, Yanwei Liu, Hailiang Sun

Int J Mol Sci. 2024 Mar; 25(6): 3315. Published online 2024 Mar 14. doi: 10.3390/ijms25063315

PMCID:: PMC10970474

Abstract Article PDF–4.2M

Select item 100489175.

TRIM21 Expression as a Prognostic Biomarker for Progression-Free Survival in HNSCC

Amelie von Bernuth, Julika Ribbat-Idel, Luise Klapper, Tobias Jagomast, Dirk Rades, Anke Leichtle, Ralph Pries, Karl-Ludwig Bruchhage, Sven Perner, Anne Offermann, Verena Sailer, Christian Idel

Int J Mol Sci. 2023 Mar; 24(6): 5140. Published online 2023 Mar 7. doi: 10.3390/ijms24065140

PMCID:: PMC10048917

Abstract Article PDF–2.4M

Select item 99355466.

TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models

Jun-Yan Li, Yin Zhao, Sha Gong, Miao-Miao Wang, Xu Liu, Qing-Mei He, Ying-Qin Li, Sheng-Yan Huang, Han Qiao, Xi-Rong Tan, Ming-Liang Ye, Xun-Hua Zhu, Shi-Wei He, Qian Li, Ye-Lin Liang, Kai-Lin Chen, Sai-Wei Huang, Qing-Jie Li, Jun Ma, Na Liu

Nat Commun. 2023; 14: 865. Published online 2023 Feb 16. doi: 10.1038/s41467-023-36523-y

PMCID:: PMC9935546

Abstract Article PDF–5.8M

Select item 98670907.

Multiple Roles of TRIM21 in Virus Infection

Xue Li, Lin Yang, Si Chen, Jiawei Zheng, Huimin Zhang, Linzhu Ren

Int J Mol Sci. 2023 Jan; 24(2): 1683. Published online 2023 Jan 14. doi: 10.3390/ijms24021683

PMCID:: PMC9867090

Abstract Article PDF–3.9M

Select item 95066798.

The emerging roles of TRIM21 in coordinating cancer metabolism, immunity and cancer treatment

Xintian Chen, Menghan Cao, Pengfei Wang, Sufang Chu, Minle Li, Pingfu Hou, Junnian Zheng, Zhongwei Li, Jin Bai

Front Immunol. 2022; 13: 968755. Published online 2022 Sep 9. doi: 10.3389/fimmu.2022.968755

PMCID:: PMC9506679

Abstract Article PDF–1.3M

Select item 85337769.

A Promising Intracellular Protein-Degradation Strategy: TRIMbody-Away Technique Based on Nanobody Fragment

Gang Chen, Yu Kong, You Li, Ailing Huang, Chunyu Wang, Shanshan Zhou, Zhenlin Yang, Yanling Wu, Jianke Ren, Tianlei Ying

Biomolecules. 2021 Oct; 11(10): 1512. Published online 2021 Oct 14. doi: 10.3390/biom11101512

PMCID:: PMC8533776

Abstract Article PDF–4.1M

Select item 827784510.

Induced TRIM21 ISGylation by IFN-β enhances p62 ubiquitination to prevent its autophagosome targeting

Jie Jin, Xianbin Meng, Yi Huo, Haiteng Deng

Cell Death Dis. 2021 Jul; 12(7): 697. Published online 2021 Jul 13. doi: 10.1038/s41419-021-03989-x

PMCID:: PMC8277845

Abstract Article PDF–3.1M

Select item 824177811.

TRIM21 Polymorphisms are associated with Susceptibility and Clinical Status of Oral Squamous Cell Carcinoma patients

Chun-Yi Chuang, Yi-Chung Chien, Chiao-Wen Lin, Chia-Hsuan Chou, Shuo-Chueh Chen, Chun-Lin Liu, Li-Yuan Bai, Shun-Fa Yang, Yung-Luen Yu

Int J Med Sci. 2021; 18(13): 2997–3003. Published online 2021 Jun 11. doi: 10.7150/ijms.56614

PMCID:: PMC8241778

Abstract Article PDF–451K

Select item 807435112.

TRIM21 inhibits porcine epidemic diarrhea virus proliferation by proteasomal degradation of the nucleocapsid protein

Hua Wang, Xiaoyong Chen, Ning Kong, Yajuan Jiao, Dage Sun, Sujie Dong, Wenzhen Qin, Huanjie Zhai, Lingxue Yu, Hao Zheng, Wu Tong, Hai Yu, Guangzhi Tong, Tongling Shan

Arch Virol. 2021; 166(7): 1903–1911. Published online 2021 Apr 26. doi: 10.1007/s00705-021-05080-4

PMCID:: PMC8074351

Abstract Article PDF–1.8M

Select item 743191513.

Autoantigen TRIM21/Ro52 is expressed on the surface of antigen-presenting cells and its enhanced expression in Sjögren’s syndrome is associated with B cell hyperactivity and type I interferon activity

Maarten R Hillen, Katia Urso, Emma Koppe, Ana Pinheiro Lopes, Sofie L M Blokland, Aridaman Pandit, Tom Slocombe, André van Maurik, Joel A G van Roon, Timothy R D J Radstake

RMD Open. 2020; 6(2): e001184. Published online 2020 Jun 15. doi: 10.1136/rmdopen-2020-001184