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Select item 73506571.

Primary fibroblast co-culture stimulates growth and metabolism in Sdhb-impaired mouse pheochromocytoma MTT cells

Susan Richter, Vanessa D’Antongiovanni, Serena Martinelli, Nicole Bechmann, Maria Riverso, David M. Poitz, Karel Pacak, Graeme Eisenhofer, Massimo Mannelli, Elena Rapizzi

Cell Tissue Res. Author manuscript; available in PMC 2020 Jul 10.

Published in final edited form as: Cell Tissue Res. 2018 Dec; 374(3): 473–485. Published online 2018 Aug 29. doi: 10.1007/s00441-018-2907-x

PMCID:: PMC7350657

Abstract Article PDF–3.4M

Select item 45914702.

Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis

Simone Cardaci, Liang Zheng, Gillian MacKay, Niels J.F. van den Broek, Elaine D. MacKenzie, Colin Nixon, David Stevenson, Sergey Tumanov, Vinay Bulusu, Jurre J. Kamphorst, Alexei Vazquez, Stewart Fleming, Francesca Schiavi, Gabriela Kalna, Karen Blyth, Douglas Strathdee, Eyal Gottlieb

Nat Cell Biol. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Nat Cell Biol. 2015 Oct; 17(10): 1317–1326. Published online 2015 Aug 24. doi: 10.1038/ncb3233

PMCID:: PMC4591470

Abstract Article PDF–2.4M

Select item 92332993.

β-Cell Succinate Dehydrogenase Deficiency Triggers Metabolic Dysfunction and Insulinopenic Diabetes

Sooyeon Lee, Haixia Xu, Aidan Van Vleck, Alex M. Mawla, Albert Mao Li, Jiangbin Ye, Mark O. Huising, Justin P. Annes

Diabetes. 2022 Jul; 71(7): 1439–1453. Published online 2022 Apr 26. doi: 10.2337/db21-0834

PMCID:: PMC9233299

Abstract Article PDF–82M

Select item 44228914.

Pituitary Adenoma With Paraganglioma/Pheochromocytoma (3PAs) and Succinate Dehydrogenase Defects in Humans and Mice

Paraskevi Xekouki, Eva Szarek, Petra Bullova, Alessio Giubellino, Martha Quezado, Spyridon A. Mastroyannis, Panagiotis Mastorakos, Christopher A. Wassif, Margarita Raygada, Nadia Rentia, Louis Dye, Antony Cougnoux, Deloris Koziol, Maria de La Luz Sierra, Charalampos Lyssikatos, Elena Belyavskaya, Carl Malchoff, Jessica Moline, Charis Eng, Louis James Maher, III, Karel Pacak, Maya Lodish, Constantine A. Stratakis

J Clin Endocrinol Metab. 2015 May; 100(5): E710–E719. Published online 2015 Feb 19. doi: 10.1210/jc.2014-4297

PMCID:: PMC4422891

Abstract Article

Select item 95362745.

Succinate dehydrogenase inversely regulates red cell distribution width and healthy life span in chronically hypoxic mice

Bora E. Baysal, Abdulrahman A. Alahmari, Tori C. Rodrick, Debra Tabaczynski, Leslie Curtin, Mukund Seshadri, Drew R. Jones, Sandra Sexton

JCI Insight. 2022 Sep 8; 7(17): e158737. Published online 2022 Sep 8. doi: 10.1172/jci.insight.158737

PMCID:: PMC9536274

Abstract Article PDF–1.4M

Select item 80969756.

GIPC2 is an endocrine-specific tumor suppressor gene for both sporadic and hereditary tumors of RET- and SDHB-, but not VHL-associated clusters of pheochromocytoma/paraganglioma

Yeqing Dong, Yongsheng Huang, Chengyan Fan, Liang Wang, Ran Zhang, Wenhua Li, Zhengguang Guo, Dong Wang, Zhi Zheng

Cell Death Dis. 2021 May; 12(5): 444. Published online 2021 May 4. doi: 10.1038/s41419-021-03731-7

PMCID:: PMC8096975

Abstract Article PDF–3.6M

Select item 46326467.

Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism

Charlotte Lussey-Lepoutre, Kate E. R. Hollinshead, Christian Ludwig, Mélanie Menara, Aurélie Morin, Luis-Jaime Castro-Vega, Seth J. Parker, Maxime Janin, Cosimo Martinelli, Chris Ottolenghi, Christian Metallo, Anne-Paule Gimenez-Roqueplo, Judith Favier, Daniel A. Tennant

Nat Commun. 2015; 6: 8784. Published online 2015 Nov 2. doi: 10.1038/ncomms9784

PMCID:: PMC4632646

Abstract Article PDF–1.0M

Select item 31573458.

Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity

Lydia W. S. Finley, Wilhelm Haas, Valérie Desquiret-Dumas, Douglas C. Wallace, Vincent Procaccio, Steven P. Gygi, Marcia C. Haigis

PLoS One. 2011; 6(8): e23295. Published online 2011 Aug 17. doi: 10.1371/journal.pone.0023295

PMCID:: PMC3157345

Abstract Article PDF–1.1M

Select item 93321119.

Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation

Xuyong Chen, Benjamin Sunkel, Meng Wang, Siwen Kang, Tingting Wang, JN Rashida Gnanaprakasam, Lingling Liu, Teresa A. Cassel, David A. Scott, Ana M. Muñoz-Cabello, Jose Lopez-Barneo, Jun Yang, Andrew N. Lane, Gang Xin, Benjamin Stanton, Teresa W.-M. Fan, Ruoning Wang

Sci Immunol. Author manuscript; available in PMC 2022 Oct 29.

Published in final edited form as: Sci Immunol. 2022 Apr 29; 7(70): eabm8161. Published online 2022 Apr 29. doi: 10.1126/sciimmunol.abm8161

PMCID:: PMC9332111

Abstract Article PDF–3.6M

Select item 893905310.

SDHB knockout and succinate accumulation are insufficient for tumorigenesis but dual SDHB/NF1 loss yields SDHx-like pheochromocytomas

Neali Armstrong, Claire M. Storey, Sarah E. Noll, Katherine Margulis, Myat Han Soe, Haixia Xu, Benjamin Yeh, Lauren Fishbein, Electron Kebebew, Brooke E. Howitt, Richard N. Zare, Julien Sage, Justin P. Annes

Cell Rep. Author manuscript; available in PMC 2022 Mar 22.

Published in final edited form as: Cell Rep. 2022 Mar 1; 38(9): 110453. doi: 10.1016/j.celrep.2022.110453

PMCID:: PMC8939053

Abstract Article PDF–3.1M

Select item 258221911.

Mitochondrial mechanism of neuroprotection by CART

Peizhong Mao, Ardi Ardeshiri, Rachel Jacks, Sufang Yang, Patricia D. Hurn, Nabil J. Alkayed

Eur J Neurosci. Author manuscript; available in PMC 2008 Nov 11.

Published in final edited form as: Eur J Neurosci. 2007 Aug; 26(3): 624–632. Published online 2007 Jul 18. doi: 10.1111/j.1460-9568.2007.05691.x

PMCID:: PMC2582219

Abstract Article PDF–1.0M

Select item 338766012.

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

Mengtao Xiao, Hui Yang, Wei Xu, Shenghong Ma, Huaipeng Lin, Honguang Zhu, Lixia Liu, Ying Liu, Chen Yang, Yanhui Xu, Shimin Zhao, Dan Ye, Yue Xiong, Kun-Liang Guan

Genes Dev. 2012 Jun 15; 26(12): 1326–1338. doi: 10.1101/gad.191056.112

Correction in:: Genes Dev. 2015 Apr 15; 29(8): 887.

PMCID:: PMC3387660

Abstract Article PDF–2.0M

Select item 803986413.

Itaconate confers tolerance to late NLRP3 inflammasome activation

Monika Bambouskova, Lucie Potuckova, Tomas Paulenda, Martina Kerndl, Denis A. Mogilenko, Kate Lizotte, Amanda Swain, Sebastian Hayes, Ryan D. Sheldon, Hyeryun Kim, Unnati Kapadnis, Abigail E. Ellis, Christine Isaguirre, Samantha Burdess, Anwesha Laha, Gaya K. Amarasinghe, Victor Chubukov, Thomas P. Roddy, Michael S. Diamond, Russell G. Jones, Donald M. Simons, Maxim N. Artyomov

Cell Rep. Author manuscript; available in PMC 2021 Apr 12.

Published in final edited form as: Cell Rep. 2021 Mar 9; 34(10): 108756. doi: 10.1016/j.celrep.2021.108756

PMCID:: PMC8039864

Abstract Article PDF–1.2M

Select item 185051214.

Mitochondrial Alterations Caused by Defective Peroxisomal Biogenesis in a Mouse Model for Zellweger Syndrome (PEX5 Knockout Mouse)

Eveline Baumgart, Ilse Vanhorebeek, Markus Grabenbauer, Marcel Borgers, Peter E. Declercq, H. Dariush Fahimi, Myriam Baes

Am J Pathol. 2001 Oct; 159(4): 1477–1494. doi: 10.1016/S0002-9440(10)62534-5

PMCID:: PMC1850512

Abstract Article PDF–2.2M

Select item 1029015015.

Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice

Anna Park, Kwang-eun Kim, Isaac Park, Sang Heon Lee, Kun-Young Park, Minkyo Jung, Xiaoxu Li, Maroun Bou Sleiman, Su Jeong Lee, Dae-Soo Kim, Jaehoon Kim, Dae-Sik Lim, Eui-Jeon Woo, Eun Woo Lee, Baek Soo Han, Kyoung-Jin Oh, Sang Chul Lee, Johan Auwerx, Ji Young Mun, Hyun-Woo Rhee, Won Kon Kim, Kwang-Hee Bae, Jae Myoung Suh

Nat Commun. 2023; 14: 3746. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39106-z

PMCID:: PMC10290150

Abstract Article PDF–1.7M

Select item 873323216.

The mitochondrial protease LONP1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals

Xiaoqiang Sheng, Chuanming Liu, Guijun Yan, Guangyu Li, Jingyu Liu, Yanjun Yang, Shiyuan Li, Zhongxun Li, Jidong Zhou, Xin Zhen, Yang Zhang, Zhenyu Diao, Yali Hu, Chuanhai Fu, Bin Yao, Chaojun Li, Yu Cao, Bin Lu, Zhongzhou Yang, Yingying Qin, Haixiang Sun, Lijun Ding

EBioMedicine. 2022 Jan; 75: 103790. Published online 2021 Dec 30. doi: 10.1016/j.ebiom.2021.103790

PMCID:: PMC8733232

Abstract Article PDF–4.2M

Select item 682604017.

A concerted metabolic shift in early forebrain alters the CSF proteome and depends on MYC downregulation for mitochondrial maturation

Ryann M. Fame, Morgan L. Shannon, Kevin F. Chau, Joshua P. Head, Maria K. Lehtinen

Development. 2019 Oct 15; 146(20): dev182857. Published online 2019 Oct 24. doi: 10.1242/dev.182857

PMCID:: PMC6826040

Abstract Article

Select item 498526718.

Perinatal licensing of thermogenesis by IL-33 and ST2

Justin I. Odegaard, Min-Woo Lee, Yoshitaka Sogawa, Ambre M. Bertholet, Richard M. Locksley, David E. Weinberg, Yuriy Kirichok, Rahul C. Deo, Ajay Chawla

Cell. Author manuscript; available in PMC 2017 Aug 11.

Published in final edited form as: Cell. 2016 Aug 11; 166(4): 841–854. Published online 2016 Jul 21. doi: 10.1016/j.cell.2016.06.040

Correction in:: Cell. 2017 Dec 14; 171(7): 1707.

PMCID:: PMC4985267

Abstract Article PDF–6.3M

Select item 733879919.

FBXL4 deficiency increases mitochondrial removal by autophagy

David Alsina, Oleksandr Lytovchenko, Aleksandra Schab, Ilian Atanassov, Florian A Schober, Min Jiang, Camilla Koolmeister, Anna Wedell, Robert W Taylor, Anna Wredenberg, Nils‐Göran Larsson

EMBO Mol Med. 2020 Jul 7; 12(7): e11659. Published online 2020 Jun 11. doi: 10.15252/emmm.201911659

PMCID:: PMC7338799

Abstract Article PDF–1.2M

Select item 742864520.

Stress‐Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics

Jessica M. Ponce, Grace Coen, Kathryn M. Spitler, Nikola Dragisic, Ines Martins, Antentor Hinton, Jr, Margaret Mungai, Satya Murthy Tadinada, Hao Zhang, Gavin Y. Oudit, Long‐Sheng Song, Na Li, Peter Sicinski, Stefan Strack, E. Dale Abel, Colleen Mitchell, Duane D. Hall, Chad E. Grueter

J Am Heart Assoc. 2020 Apr 7; 9(7): e014366. Published online 2020 Apr 4. doi: 10.1161/JAHA.119.014366

PMCID:: PMC7428645

Abstract Article PDF–1.9M

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PMC Links for Gene (Select 67680) (66)
PMC
CCL25 C-C motif chemokine ligand 25 [Homo sapiens]
CCL25 C-C motif chemokine ligand 25 [Homo sapiens]
Gene ID:6370

Gene
Gene Links for GEO Profiles (Select 132549716) (1)
Gene
Gm19149 predicted gene, 19149 [Mus musculus]
Gm19149 predicted gene, 19149 [Mus musculus]
Gene ID:100418339

Gene
related_functional_gene_67680[group] AND (alive[prop]) (1)
Gene

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