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Select item 75040701.

Characterization of Two Novel Variants of the Steroidogenic Acute Regulatory Protein Identified in a Girl with Classic Lipoid Congenital Adrenal Hyperplasia

Efstathios Katharopoulos, Natascia Di Iorgi, Paula Fernandez-Alvarez, Amit V. Pandey, Michael Groessl, Shraddha Dubey, Núria Camats, Flavia Napoli, Giuseppa Patti, Marilea Lezzi, Mohamad Maghnie, Christa E. Flück

Int J Mol Sci. 2020 Sep; 21(17): 6185. Published online 2020 Aug 27. doi: 10.3390/ijms21176185

PMCID:: PMC7504070

Abstract Article PDF–1.8M

Select item 66085772.

Overexpression of the steroidogenic acute regulatory protein in breast cancer: Regulation by histone deacetylase inhibition

Pulak R. Manna, Ahsen U Ahmed, David Vartak, Deborah Molehin, Kevin Pruitt

Biochem Biophys Res Commun. Author manuscript; available in PMC 2020 Feb 5.

Published in final edited form as: Biochem Biophys Res Commun. 2019 Feb 5; 509(2): 476–482. Published online 2018 Dec 27. doi: 10.1016/j.bbrc.2018.12.145

PMCID:: PMC6608577

Abstract Article PDF–1.2M

Select item 56267553.

Mechanism of mRNA-STAR domain interaction: Molecular dynamics simulations of Mammalian Quaking STAR protein

Monika Sharma, C. R. Anirudh

Sci Rep. 2017; 7: 12567. Published online 2017 Oct 3. doi: 10.1038/s41598-017-12930-2

PMCID:: PMC5626755

Abstract Article PDF–3.9M

Select item 55229674.

Mutation Spectrum of STAR and the Founder Effect of p.Q258* in Korean Patients with Congenital Lipoid Adrenal Hyperplasia

Eungu Kang, Yoon-Myung Kim, Gu-Hwan Kim, Beom Hee Lee, Han-Wook Yoo, Jin-Ho Choi

Mol Med. 2017; 23: 149–154. Published online 2017 May 2. doi: 10.2119/molmed.2017.00023

PMCID:: PMC5522967

Abstract Article PDF–518K

Select item 47070565.

Role of the steroidogenic acute regulatory protein in health and disease

Pulak R. Manna, Cloyce L. Stetson, Andrzej T. Slominski, Kevin Pruitt

Endocrine. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: Endocrine. 2016 Jan; 51(1): 7–21. Published online 2015 Aug 14. doi: 10.1007/s12020-015-0715-6

PMCID:: PMC4707056

Abstract Article PDF–804K

Select item 40907136.

Upregulation of Steroidogenic Acute Regulatory Protein by Hypoxia Stimulates Aldosterone Synthesis in Pulmonary Artery Endothelial Cells to Promote Pulmonary Vascular Fibrosis

Bradley A. Maron, William M. Oldham, Stephen Y. Chan, Sara O. Vargas, Elena Arons, Ying-Yi Zhang, Joseph Loscalzo, Jane A. Leopold

Circulation. Author manuscript; available in PMC 2015 Jul 8.

Published in final edited form as: Circulation. 2014 Jul 8; 130(2): 168–179. Published online 2014 Apr 28. doi: 10.1161/CIRCULATIONAHA.113.007690

PMCID:: PMC4090713

Abstract Article PDF–3.0M

Select item 37019187.

Identification of Novel Mutations in STAR Gene in Patients with Lipoid Congenital Adrenal Hyperplasia: A First Report from India

Lakshmi Vasudevan, Rajesh Joshi, Dhanjit Kumar Das, Sudha Rao, Daksha Sanghavi, Shiny Babu, Parag M. Tamhankar

J Clin Res Pediatr Endocrinol. 2013 Jun; 5(2): 121–124. Published online 2013 May 30. doi: 10.4274/Jcrpe.927

PMCID:: PMC3701918

Abstract Article PDF–457K

Select item 34045128.

cAMP stimulation of STAR expression and cholesterol metabolism is modulated by co-expression of labile suppressors of transcription and mRNA turnover

Colin R Jefcoate, Jinwoo Lee, Nadia Cherradi, Hiroshi Takemori H, Haichuan Duan

Mol Cell Endocrinol. Author manuscript; available in PMC 2012 Jul 25.

Published in final edited form as: Mol Cell Endocrinol. 2011 Apr 10; 336(1-2): 53–62. Published online 2010 Dec 13. doi: 10.1016/j.mce.2010.12.006

PMCID:: PMC3404512

Abstract Article PDF–986K

Select item 31035409.

Characterization of Novel StAR (Steroidogenic Acute Regulatory Protein) Mutations Causing Non-Classic Lipoid Adrenal Hyperplasia

Christa E. Flück, Amit V. Pandey, Bernhard Dick, Núria Camats, Mónica Fernández-Cancio, María Clemente, Miquel Gussinyé, Antonio Carrascosa, Primus E. Mullis, Laura Audi

PLoS One. 2011; 6(5): e20178. Published online 2011 May 27. doi: 10.1371/journal.pone.0020178

PMCID:: PMC3103540

Abstract Article PDF–637K

Select item 292891010.

Clinical, Genetic, and Functional Characterization of Four Patients Carrying Partial Loss-of-Function Mutations in the Steroidogenic Acute Regulatory Protein (StAR)

Taninee Sahakitrungruang, Raymond E. Soccio, Mariarosaria Lang-Muritano, Joanna M. Walker, John C. Achermann, Walter L. Miller

J Clin Endocrinol Metab. 2010 Jul; 95(7): 3352–3359. Published online 2010 May 5. doi: 10.1210/jc.2010-0437

Correction in:: J Clin Endocrinol Metab. December 1, 2011; 96(12): 3908.

PMCID:: PMC2928910

Abstract Article

Select item 276149311.

Overexpression of mitochondrial cholesterol delivery protein, StAR, decreases intracellular lipids and inflammatory factors secretion in macrophages

Yanxia Ning, Qianming Bai, Hong Lu, Xiaobo Li, William M. Pandak, Fengdi Zhao, Sifeng Chen, Shunlin Ren, Lianhua Yin

Atherosclerosis. Author manuscript; available in PMC 2009 Oct 14.

Published in final edited form as: Atherosclerosis. 2009 May; 204(1): 114–120. Published online 2008 Sep 13. doi: 10.1016/j.atherosclerosis.2008.09.006

PMCID:: PMC2761493

Abstract Article PDF–2.0M

Select item 1940712.

Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: Implications for the mechanism of StAR action

Futoshi Arakane, Teruo Sugawara, Hideaki Nishino, Zhiming Liu, John A. Holt, Debkumar Pain, Douglas M. Stocco, Walter L. Miller, Jerome F. Strauss, III

Proc Natl Acad Sci U S A. 1996 Nov 26; 93(24): 13731–13736. doi: 10.1073/pnas.93.24.13731

PMCID:: PMC19407

Abstract Article PDF–581K

Select item 982090313.

Expression and Function of StAR in Cancerous and Non-Cancerous Human and Mouse Breast Tissues: New Insights into Diagnosis and Treatment of Hormone-Sensitive Breast Cancer

Pulak R. Manna, Sabarish Ramachandran, Jangampalli Adi Pradeepkiran, Deborah Molehin, Isabel Castro-Piedras, Kevin Pruitt, Vadivel Ganapathy, P. Hemachandra Reddy

Int J Mol Sci. 2023 Jan; 24(1): 758. Published online 2023 Jan 1. doi: 10.3390/ijms24010758

PMCID:: PMC9820903

Abstract Article PDF–3.0M

Select item 885781014.

Growth differentiation factor-11 downregulates steroidogenic acute regulatory protein expression through ALK5-mediated SMAD3 signaling pathway in human granulosa-lutein cells

Qiongqiong Jia, Boqun Liu, Xuan Dang, Yanjie Guo, Xiaoyu Han, Tinglin Song, Jung-Chien Cheng, Lanlan Fang

Reprod Biol Endocrinol. 2022; 20: 34. Published online 2022 Feb 19. doi: 10.1186/s12958-022-00912-7

PMCID:: PMC8857810

Abstract Article PDF–3.6M

Select item 857379115.

STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway

Laura Conde de la Rosa, Carmen Garcia-Ruiz, Carmen Vallejo, Anna Baulies, Susana Nuñez, Maria J. Monte, Jose J. G. Marin, Lucia Baila-Rueda, Ana Cenarro, Fernando Civeira, Josep Fuster, Juan C. Garcia-Valdecasas, Joana Ferrer, Michael Karin, Vicent Ribas, Jose C. Fernandez-Checa

J Hepatol. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: J Hepatol. 2021 Jun; 74(6): 1429–1441. Published online 2021 Jan 27. doi: 10.1016/j.jhep.2021.01.028

PMCID:: PMC8573791

Abstract Article PDF–3.3M

Select item 493739816.

Fractalkine restores the decreased expression of StAR and progesterone in granulosa cells from patients with polycystic ovary syndrome

Shuo Huang, Yanli Pang, Jie Yan, Shengli Lin, Yue Zhao, Li Lei, Liying Yan, Rong Li, Caihong Ma, Jie Qiao

Sci Rep. 2016; 6: 26205. Published online 2016 Jul 8. doi: 10.1038/srep26205

PMCID:: PMC4937398

Abstract Article PDF–949K

Select item 414885617.

Structural Basis for Regulation of the Human Acetyl-CoA Thioesterase 12 and Interactions with the Steroidogenic Acute Regulatory Protein-related Lipid Transfer (START) Domain

Crystall M. D. Swarbrick, Noelia Roman, Nathan Cowieson, Edward I. Patterson, Jeffrey Nanson, Marina I. Siponen, Helena Berglund, Lari Lehtiö, Jade K. Forwood

J Biol Chem. 2014 Aug 29; 289(35): 24263–24274. Published online 2014 Jul 7. doi: 10.1074/jbc.M114.589408