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Items: 1 to 20 of 203

1.
STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential
Meng Lin, Amy T. Ku, Jie Dong, Fei Yue, Weiyu Jiang, Ahmed Atef Ibrahim, Fanglue Peng, Chad J. Creighton, Chandandeep Nagi, Carolina Gutierrez, Jeffrey M. Rosen, Xiang H.-F. Zhang, Susan G. Hilsenbeck, Xi Chen, Yi-Chieh Nancy Du, Shixia Huang, Aiping Shi, Zhimin Fan, Yi Li
Oncogene. Author manuscript; available in PMC 2023 May 1.
Published in final edited form as: Oncogene. 2022 Nov; 41(48): 5214–5222. Published online 2022 Oct 19. doi: 10.1038/s41388-022-02500-w
PMCID:
PMC9701164
AbstractArticlePDF–991K
2.
Genomic Mutations of the STAT5 Transcription Factor Are Associated with Human Cancer and Immune Diseases
Uijin Kim, Ha Youn Shin
Int J Mol Sci. 2022 Oct; 23(19): 11297. Published online 2022 Sep 25. doi: 10.3390/ijms231911297
PMCID:
PMC9569778
AbstractArticlePDF–1.0M
3.
Impaired activation of STAT5 upon IL-2 stimulation in Tregs and elevated sIL-2R in Sjögren’s syndrome
Magdalena Keindl, Richard Davies, Brith Bergum, Johan G. Brun, Daniel Hammenfors, Roland Jonsson, Valeriya Lyssenko, Silke Appel
Arthritis Res Ther. 2022; 24: 101. Published online 2022 May 7. doi: 10.1186/s13075-022-02769-y
PMCID:
PMC9077945
AbstractArticlePDF–2.6M
4.
Serine residues 726 and 780 have nonredundant roles regulating STAT5a activity in luminal breast cancer
Alicia E. Woock, Jacqueline M. Grible, Amy L. Olex, J. Chuck Harrell, Patricija Zot, Michael Idowu, Charles V. Clevenger
Sci Rep. 2021; 11: 13506. Published online 2021 Jun 29. doi: 10.1038/s41598-021-92830-8
PMCID:
PMC8242097
AbstractArticlePDF–6.0M
5.
Therapeutic delivery of siRNA with polymeric carriers to down-regulate STAT5A expression in high-risk B-cell acute lymphoblastic leukemia (B-ALL)
Mahsa Mohseni, Cezary Kucharski, Remant Bahadur K. C., Mohammad Nasrullah, Xiaoyan Jiang, Hasan Uludağ, Joseph Brandwein
PLoS One. 2021; 16(6): e0251719. Published online 2021 Jun 22. doi: 10.1371/journal.pone.0251719
PMCID:
PMC8219370
AbstractArticlePDF–2.4M
6.
Mitochondrial STAT5A promotes metabolic remodeling and the Warburg effect by inactivating the pyruvate dehydrogenase complex
Liang Zhang, Jianong Zhang, Yan Liu, Pingzhao Zhang, Ji Nie, Rui Zhao, Qin Shi, Huiru Sun, Dongyue Jiao, Yingji Chen, Xiaying Zhao, Yan Huang, Yao Li, Jian-Yuan Zhao, Wei Xu, Shi-Min Zhao, Chenji Wang
Cell Death Dis. 2021 Jul; 12(7): 634. Published online 2021 Jun 19. doi: 10.1038/s41419-021-03908-0
PMCID:
PMC8214628
AbstractArticlePDF–3.4M
7.
Acriflavine targets oncogenic STAT5 signaling in myeloid leukemia cells
Rawan Hallal, Rawan Nehme, Marie Brachet‐Botineau, Ali Nehme, Hassan Dakik, Margaux Deynoux, Persio Dello Sbarba, Yves Levern, Kazem Zibara, Fabrice Gouilleux, Frédéric Mazurier
J Cell Mol Med. 2020 Sep; 24(17): 10052–10062. Published online 2020 Jul 15. doi: 10.1111/jcmm.15612
PMCID:
PMC7520299
AbstractArticlePDF–1.9M
8.
High activation of STAT5A drives peripheral T-cell lymphoma and leukemia
Barbara Maurer, Harini Nivarthi, Bettina Wingelhofer, Ha Thi Thanh Pham, Michaela Schlederer, Tobias Suske, Reinhard Grausenburger, Ana-Iris Schiefer, Michaela Prchal-Murphy, Doris Chen, Susanne Winkler, Olaf Merkel, Christoph Kornauth, Maximilian Hofbauer, Birgit Hochgatterer, Gregor Hoermann, Andrea Hoelbl-Kovacic, Jana Prochazkova, Cosimo Lobello, Abbarna A. Cumaraswamy, Johanna Latzka, Melitta Kitzwögerer, Andreas Chott, Andrea Janikova, Šárka Pospíšilova, Joanna I. Loizou, Stefan Kubicek, Peter Valent, Thomas Kolbe, Florian Grebien, Lukas Kenner, Patrick T. Gunning, Robert Kralovics, Marco Herling, Mathias Müller, Thomas Rülicke, Veronika Sexl, Richard Moriggl
Haematologica. 2020 Feb; 105(2): 435–447. Prepublished online 2019 May 23. doi: 10.3324/haematol.2019.216986
PMCID:
PMC7012494
AbstractArticlePDF–7.1M
9.
Positive STAT5 protein and locus amplification status predicts recurrence after radical prostatectomy to assist clinical precision management of prostate cancer
Bassem R. Haddad, Andrew Erickson, Vindhya Udhane, Peter S. LaViolette, Janice D. Rone, Markku A. Kallajoki, William A. See, Antti Rannikko, Tuomas Mirtti, Marja T. Nevalainen
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2019 Oct; 28(10): 1642–1651. Published online 2019 Jul 10. doi: 10.1158/1055-9965.EPI-18-1358
PMCID:
PMC6774884
AbstractArticlePDF–1.0M
10.
Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells
Barbara Peter, Siham Bibi, Gregor Eisenwort, Bettina Wingelhofer, Daniela Berger, Gabriele Stefanzl, Katharina Blatt, Harald Herrmann, Emir Hadzijusufovic, Gregor Hoermann, Thomas Hoffmann, Juliana Schwaab, Mohamad Jawhar, Michael Willmann, Wolfgang R. Sperr, Johannes Zuber, Karl Sotlar, Hans-Peter Horny, Richard Moriggl, Andreas Reiter, Michel Arock, Peter Valent
Leukemia. Author manuscript; available in PMC 2018 Jul 10.
Published in final edited form as: Leukemia. 2018 Apr; 32(4): 1016–1022. Published online 2017 Nov 29. doi: 10.1038/leu.2017.338
PMCID:
PMC6037300
AbstractArticlePDF–1.1M
11.
Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex
Safder S. Ganaie, Wei Zou, Peng Xu, Xuefeng Deng, Steve Kleiboeker, Jianming Qiu
PLoS Pathog. 2017 May; 13(5): e1006370. Published online 2017 May 1. doi: 10.1371/journal.ppat.1006370
PMCID:
PMC5426800
AbstractArticlePDF–44M
12.
STAT-5 is activated constitutively in T cells, B cells and monocytes from patients with primary Sjögren's syndrome
M Pertovaara, O Silvennoinen, P Isomäki
Clin Exp Immunol. 2015 Jul; 181(1): 29–38. Published online 2015 Apr 23. doi: 10.1111/cei.12614
PMCID:
PMC4469153
AbstractArticlePDF–379K
13.
Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes
Amy R Peck, Agnieszka K Witkiewicz, Chengbao Liu, Alexander C Klimowicz, Ginger A Stringer, Edward Pequignot, Boris Freydin, Ning Yang, Adam Ertel, Thai H Tran, Melanie A Girondo, Anne L Rosenberg, Jeffrey A Hooke, Albert J Kovatich, Craig D Shriver, David L Rimm, Anthony M Magliocco, Terry Hyslop, Hallgeir Rui
Breast Cancer Res. 2012; 14(5): R130. Published online 2012 Oct 4. doi: 10.1186/bcr3328
PMCID:
PMC4053108
AbstractArticlePDF–4.1M
14.
An N-terminal splice variant of human Stat5a that interacts with different transcription factors is the dominant form expressed in invasive ductal carcinoma
Dunyong Tan, KuanHui E. Chen, Changhui Deng, Peizhi Tang, Jianjun Huang, Trina Mansour, Richard A. Luben, Ameae M. Walker
Cancer Lett. Author manuscript; available in PMC 2015 Apr 28.
Published in final edited form as: Cancer Lett. 2014 Apr 28; 346(1): 148–157. Published online 2013 Dec 30. doi: 10.1016/j.canlet.2013.12.030
PMCID:
PMC3959904
AbstractArticlePDF–1.4M
15.
STAT5 polarization promotes iTregs and suppresses human T-cell alloresponses while preserving CTL capacity
Brian C. Betts, Anandharaman Veerapathran, Joseph Pidala, Xue-Zhong Yu, Claudio Anasetti
J Leukoc Biol. 2014 Feb; 95(2): 205–213. doi: 10.1189/jlb.0313154
PMCID:
PMC3896660
AbstractArticle
16.
The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors
Erik A. Nelson, Sarah R. Walker, Ellen Weisberg, Michal Bar-Natan, Rosemary Barrett, Laurie B. Gashin, Shariya Terrell, Josephine L. Klitgaard, Loredana Santo, Martha R. Addorio, Benjamin L. Ebert, James D. Griffin, David A. Frank
Blood. 2011 Mar 24; 117(12): 3421–3429. Prepublished online 2011 Jan 13. doi: 10.1182/blood-2009-11-255232
PMCID:
PMC3069678
AbstractArticle
17.
Single-Cell STAT5 Signal Transduction Profiling in Normal and Leukemic Stem and Progenitor Cell Populations Reveals Highly Distinct Cytokine Responses
Lina Han, Albertus T. J. Wierenga, Marjan Rozenveld-Geugien, Kim van de Lande, Edo Vellenga, Jan Jacob Schuringa
PLoS One. 2009; 4(11): e7989. Published online 2009 Nov 24. doi: 10.1371/journal.pone.0007989
PMCID:
PMC2776352
AbstractArticlePDF–621K
18.
Structural characterization of unphosphorylated STAT5a oligomerization equilibrium in solution by small-angle X-ray scattering
Pau Bernadó, Yolanda Pérez, Jascha Blobel, Juan Fernández-Recio, Dmitri I Svergun, Miquel Pons
Protein Sci. 2009 Apr; 18(4): 716–726. Published online 2009 Feb 10. doi: 10.1002/pro.83
PMCID:
PMC2762584
AbstractArticlePDF–493K
19.
Maximal STAT5-Induced Proliferation and Self-Renewal at Intermediate STAT5 Activity Levels
Albertus T. J. Wierenga, Edo Vellenga, Jan Jacob Schuringa
Mol Cell Biol. 2008 Nov; 28(21): 6668–6680. Published online 2008 Sep 8. doi: 10.1128/MCB.01025-08
PMCID:
PMC2573230
AbstractArticlePDF–1.6M
20.
Nuclear Factor κB–dependent Gene Expression Profiling of Hodgkin's Disease Tumor Cells, Pathogenetic Significance, and Link to Constitutive Signal Transducer and Activator of Transcription 5a Activity
Michael Hinz, Petra Lemke, Ioannis Anagnostopoulos, Christine Hacker, Daniel Krappmann, Stephan Mathas, Bernd Dörken, Martin Zenke, Harald Stein, Claus Scheidereit
J Exp Med. 2002 Sep 2; 196(5): 605–617. doi: 10.1084/jem.20020062
PMCID:
PMC2194004
AbstractArticlePDF–444K

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