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Select item 53392871.

Hypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly

Hasan Tawamie, Igor Martianov, Natalie Wohlfahrt, Rebecca Buchert, Gabrielle Mengus, Steffen Uebe, Luigi Janiri, Franz Wolfgang Hirsch, Johannes Schumacher, Fulvia Ferrazzi, Heinrich Sticht, André Reis, Irwin Davidson, Roberto Colombo, Rami Abou Jamra

Am J Hum Genet. 2017 Mar 2; 100(3): 555–561. Published online 2017 Mar 2. doi: 10.1016/j.ajhg.2017.01.032

PMCID:: PMC5339287

Abstract Article PDF–618K

Select item 42370022.

De novo mutations in schizophrenia implicate synaptic networks

Menachem Fromer, Andrew J. Pocklington, David H. Kavanagh, Hywel J. Williams, Sarah Dwyer, Padhraig Gormley, Lyudmila Georgieva, Elliott Rees, Priit Palta, Douglas M. Ruderfer, Noa Carrera, Isla Humphreys, Jessica S. Johnson, Panos Roussos, Douglas D. Barker, Eric Banks, Vihra Milanova, Seth G. Grant, Eilis Hannon, Samuel A. Rose, Kimberly Chambert, Milind Mahajan, Edward M. Scolnick, Jennifer L. Moran, George Kirov, Aarno Palotie, Steven A. McCarroll, Peter Holmans, Pamela Sklar, Michael J. Owen, Shaun M. Purcell, Michael C. O’Donovan

Nature. Author manuscript; available in PMC 2014 Nov 19.

Published in final edited form as: Nature. 2014 Feb 13; 506(7487): 179–184. Published online 2014 Jan 22. doi: 10.1038/nature12929

PMCID:: PMC4237002

Abstract Article PDF–1.7M

Select item 1088633.

EWS, but Not EWS-FLI-1, Is Associated with Both TFIID and RNA Polymerase II: Interactions between Two Members of the TET Family, EWS and hTAF_II68, and Subunits of TFIID and RNA Polymerase II Complexes

Anne Bertolotti, Thomas Melot, Joël Acker, Marc Vigneron, Olivier Delattre, Laszlo Tora

Mol Cell Biol. 1998 Mar; 18(3): 1489–1497. doi: 10.1128/mcb.18.3.1489

PMCID:: PMC108863

Abstract Article PDF–729K

Select item 3982394.

Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.

G Mengus, M May, X Jacq, A Staub, L Tora, P Chambon, I Davidson

EMBO J. 1995 Apr 3; 14(7): 1520–1531. doi: 10.1002/j.1460-2075.1995.tb07138.x

PMCID:: PMC398239

Summary Page Browse PDF–2.6M

Select item 35523825.

Human TFIID binds to core promoter DNA in a reorganized structural state

Michael A. Cianfrocco, George A. Kassavetis, Patricia Grob, Jie Fang, Tamar Juven-Gershon, James T. Kadonaga, Eva Nogales

Cell. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Cell. 2013 Jan 17; 152(1-2): 120–131. doi: 10.1016/j.cell.2012.12.005

PMCID:: PMC3552382

Abstract Article PDF–4.9M

Select item 18208496.

Identification of a Small TAF Complex and Its Role in the Assembly of TAF-Containing Complexes

Màté A. Demény, Evi Soutoglou, Zita Nagy, Elisabeth Scheer, Àgnes Jànoshàzi, Magalie Richardot, Manuela Argentini, Pascal Kessler, Laszlo Tora

PLoS One. 2007; 2(3): e316. Published online 2007 Mar 21. doi: 10.1371/journal.pone.0000316

PMCID:: PMC1820849

Abstract Article PDF–505K

Select item 3980867.

Novel mechanism and factor for regulation by HIV-1 Tat.

Q Zhou, P A Sharp

EMBO J. 1995 Jan 16; 14(2): 321–328. doi: 10.1002/j.1460-2075.1995.tb07006.x

PMCID:: PMC398086

Summary Page Browse PDF–2.1M

Select item 1904568.

Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly.

P S Pendergrast, D Morrison, W P Tansey, N Hernandez

J Virol. 1996 Aug; 70(8): 5025–5034. doi: 10.1128/jvi.70.8.5025-5034.1996

PMCID:: PMC190456

Summary PDF–667K

Select item 872369.

The TFIID Components Human TAF_II140 and Drosophila BIP2 (TAF_II155) Are Novel Metazoan Homologues of Yeast TAF_II47 Containing a Histone Fold and a PHD Finger

Yann-Gaël Gangloff, Jean-Christophe Pointud, Sylvie Thuault, Lucie Carré, Christophe Romier, Selen Muratoglu, Marjorie Brand, Laszlo Tora, Jean-Louis Couderc, Irwin Davidson

Mol Cell Biol. 2001 Aug; 21(15): 5109–5121. doi: 10.1128/MCB.21.15.5109-5121.2001

PMCID:: PMC87236

Abstract Article PDF–927K

Select item 485629510.

Structure of promoter-bound TFIID and insight into human PIC assembly

Robert K. Louder, Yuan He, José Ramón López-Blanco, Jie Fang, Pablo Chacón, Eva Nogales

Nature. Author manuscript; available in PMC 2016 Sep 23.

Published in final edited form as: Nature. 2016 Mar 31; 531(7596): 604–609. Published online 2016 Mar 23. doi: 10.1038/nature17394

Correction in:: Nature. 2016 Apr 20; 536(7614): 112.

PMCID:: PMC4856295

Abstract Article PDF–5.0M

Select item 19050811.

Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex.

F Kashanchi, S N Khleif, J F Duvall, M R Sadaie, M F Radonovich, M Cho, M A Martin, S Y Chen, R Weinmann, J N Brady

J Virol. 1996 Aug; 70(8): 5503–5510. doi: 10.1128/jvi.70.8.5503-5510.1996

PMCID:: PMC190508

Summary PDF–468K

Select item 23715812.

Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function.

S H Ou, L F Garcia-Martínez, E J Paulssen, R B Gaynor

J Virol. 1994 Nov; 68(11): 7188–7199. doi: 10.1128/jvi.68.11.7188-7199.1994

PMCID:: PMC237158

Summary Page Browse PDF–3.2M

Select item 569028213.

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID

Kapil Gupta, Aleksandra A Watson, Tiago Baptista, Elisabeth Scheer, Anna L Chambers, Christine Koehler, Juan Zou, Ima Obong-Ebong, Eaazhisai Kandiah, Arturo Temblador, Adam Round, Eric Forest, Petr Man, Christoph Bieniossek, Ernest D Laue, Edward A Lemke, Juri Rappsilber, Carol V Robinson, Didier Devys, Làszlò Tora, Imre Berger

eLife. 2017; 6: e30395. Published online 2017 Nov 7. doi: 10.7554/eLife.30395

PMCID:: PMC5690282

Abstract Article PDF–4.0M

Select item 264865314.

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function

Matthew T. Knuesel, Krista D. Meyer, Carrie Bernecky, Dylan J. Taatjes

Genes Dev. 2009 Feb 15; 23(4): 439–451. doi: 10.1101/gad.1767009

PMCID:: PMC2648653

Abstract Article PDF–767K

Select item 117034615.

Three transitions in the RNA polymerase II transcription complex during initiation.

F C Holstege, U Fiedler, H T Timmers

EMBO J. 1997 Dec 15; 16(24): 7468–7480. doi: 10.1093/emboj/16.24.7468

PMCID:: PMC1170346

Summary PDF–609K

Select item 314532516.

Human Mediator Subunit Med26 Functions As A Docking Site For Transcription Elongation Factors

Hidehisa Takahashi, Tari J. Parmely, Shigeo Sato, Chieri Tomomori-Sato, Charles A. S. Banks, Stephanie E. Kong, Henrietta Szutorisz, Selene K. Swanson, Skylar Martin-Brown, Michael P. Washburn, Laurence Florens, Chris Seidel, Chengqi Lin, Edwin R. Smith, Ali Shilatifard, Ronald C. Conaway, Joan W. Conaway

Cell. Author manuscript; available in PMC 2012 Jul 8.

Published in final edited form as: Cell. 2011 Jul 8; 146(1): 92–104. doi: 10.1016/j.cell.2011.06.005

PMCID:: PMC3145325

Abstract Article PDF–1.9M

Select item 1085081817.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 449890318.

Systematic Analysis of the Protein Interaction Network for the Human Transcription Machinery Reveals the Identity of the 7SK Capping Enzyme

Célia Jeronimo, Diane Forget, Annie Bouchard, Qintong Li, Gordon Chua, Christian Poitras, Cynthia Thérien, Dominique Bergeron, Sylvie Bourassa, Jack Greenblatt, Benoit Chabot, Guy G. Poirier, Timothy R. Hughes, Mathieu Blanchette, David H. Price, Benoit Coulombe

Mol Cell. Author manuscript; available in PMC 2015 Jul 10.

Published in final edited form as: Mol Cell. 2007 Jul 20; 27(2): 262–274. doi: 10.1016/j.molcel.2007.06.027

PMCID:: PMC4498903

Abstract Article PDF–1.5M

Select item 694204419.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 674264620.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

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