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Items: 1 to 20 of 287

1.
Pharmacological inhibition of TAK1 prevents and induces regression of experimental organ fibrosis
Swarna Bale, Priyanka Verma, Bharath Yalavarthi, Scott Arthur Scarneo, Philip Hughes, M. Asif Amin, Pei-Suen Tsou, Dinesh Khanna, Timothy A.J. Haystead, Swati Bhattacharyya, John Varga
JCI Insight. 2023 Jul 24; 8(14): e165358. Published online 2023 Jul 24. doi: 10.1172/jci.insight.165358
PMCID:
PMC10443806
AbstractArticlePDF–14M
2.
Emerging role of TAK1 in the regulation of skeletal muscle mass
Anirban Roy, Vihang A. Narkar, Ashok Kumar
Bioessays. Author manuscript; available in PMC 2024 Apr 1.
Published in final edited form as: Bioessays. 2023 Apr; 45(4): e2300003. Published online 2023 Feb 15. doi: 10.1002/bies.202300003
PMCID:
PMC10023406
AbstractArticlePDF–1.4M
3.
A novel variant in MAP3K7 associated with an expanded cardiospondylocarpofacial syndrome phenotype
Fatima AbuBakr, Lauren Jeffries, Weizhen Ji, James M. McGrath, Saquib A. Lakhani
Cold Spring Harb Mol Case Stud. 2020 Jun; 6(3): a005207. doi: 10.1101/mcs.a005207
PMCID:
PMC7304360
AbstractArticlePDF–2.2M
4.
Loss of MAP3K7 sensitizes prostate cancer cells to CDK1/2 inhibition and DNA damage by disrupting homologous recombination
Satoshi Washino, Leah C. Rider, Lina Romero, Lauren K. Jillson, Trisiani Affandi, Angela M. Ohm, Elaine T. Lam, Mary E. Reyland, James C. Costello, Scott D. Cramer
Mol Cancer Res. Author manuscript; available in PMC 2020 Jun 2.
Published in final edited form as: Mol Cancer Res. 2019 Oct; 17(10): 1985–1998. Published online 2019 Jul 12. doi: 10.1158/1541-7786.MCR-18-1335
PMCID:
PMC7266379
AbstractArticlePDF–1.9M
5.
Novel phosphorylated TAK1 species with functional impact on NF-κB and β-catenin signaling in human Cutaneous T-cell lymphoma
Fernando Gallardo, Joan Bertran, Erika López-Arribillaga, Jéssica González, Silvia Menéndez, Ignacio Sánchez, Luis Colomo, Mar Iglesias, Marta Garrido, Luis Francisco Santamaría-Babí, Ferran Torres, Ramon M Pujol, Anna Bigas, Lluís Espinosa
Leukemia. 2018; 32(10): 2211–2223. Published online 2018 Feb 22. doi: 10.1038/s41375-018-0066-4
PMCID:
PMC6170395
AbstractArticlePDF–3.1M
6.
MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB
David M. Cordas dos Santos, Juliane Eilers, Alfonso Sosa Vizcaino, Elena Orlova, Martin Zimmermann, Martin Stanulla, Martin Schrappe, Kathleen Börner, Dirk Grimm, Martina U. Muckenthaler, Andreas E. Kulozik, Joachim B. Kunz
BMC Cancer. 2018; 18: 663. Published online 2018 Jun 18. doi: 10.1186/s12885-018-4525-0
PMCID:
PMC6006985
AbstractArticlePDF–2.1M
7.
TAK1 mediates microenvironment-triggered autocrine signals and promotes triple-negative breast cancer lung metastasis
Oihana Iriondo, Yarong Liu, Grace Lee, Mostafa Elhodaky, Christian Jimenez, Lin Li, Julie Lang, Pin Wang, Min Yu
Nat Commun. 2018; 9: 1994. Published online 2018 May 18. doi: 10.1038/s41467-018-04460-w
PMCID:
PMC5959931
AbstractArticlePDF–1018K
8.
Activation of TGF-β-activated kinase 1 (TAK1) restricts Salmonella Typhimurium growth by inducing AMPK activation and autophagy
Wei Liu, Yuanyuan Jiang, Jing Sun, Shizhong Geng, Zhiming Pan, Richard A. Prinz, Chengming Wang, Jun Sun, Xinan Jiao, Xiulong Xu
Cell Death Dis. 2018 May; 9(5): 570. Published online 2018 May 11. doi: 10.1038/s41419-018-0612-z
PMCID:
PMC5948208
AbstractArticlePDF–8.1M
9.
A novel MAP3K7 splice mutation causes cardiospondylocarpofacial syndrome with features of hereditary connective tissue disorder
Silvia Morlino, Marco Castori, Chiara Dordoni, Valeria Cinquina, Graziano Santoro, Paola Grammatico, Marina Venturini, Marina Colombi, Marco Ritelli
Eur J Hum Genet. 2018 Apr; 26(4): 582–586. Published online 2018 Feb 21. doi: 10.1038/s41431-017-0079-x
PMCID:
PMC5891500
AbstractArticlePDF–815K
10.
Expression and function of transforming growth factor-β-activated protein kinase 1 in gastric cancer
Yue Yang, Yudong Qiu, Mubai Tang, Zhaoshu Wu, Weidong Hu, Chaobo Chen
Mol Med Rep. 2017 Sep; 16(3): 3103–3110. Published online 2017 Jul 15. doi: 10.3892/mmr.2017.6998
PMCID:
PMC5548047
AbstractArticlePDF–1.6M
11.
The role of TAK1 expression in thyroid cancer
Pengfei Lin, Weibo Niu, Cheng Peng, Zhaoyang Zhang, Jun Niu
Int J Clin Exp Pathol. 2015; 8(11): 14449–14456. Published online 2015 Nov 1.
PMCID:
PMC4713548
AbstractArticlePDF–955K
12.
TAK1 Regulates Hepatic Cell Survival and Carcinogenesis
Yoon Seok Roh, Jingyi Song, Ekihiro Seki
J Gastroenterol. Author manuscript; available in PMC 2015 Feb 1.
Published in final edited form as: J Gastroenterol. 2014 Feb; 49(2): 185–194. Published online 2014 Jan 21. doi: 10.1007/s00535-013-0931-x
PMCID:
PMC3952073
AbstractArticlePDF–2.4M
13.
Loss of TAK1 increases cell traction force in a ROS-dependent manner to drive epithelial–mesenchymal transition of cancer cells
C R I Lam, C Tan, Z Teo, C Y Tay, T Phua, Y L Wu, P Q Cai, L P Tan, X Chen, P Zhu, N S Tan
Cell Death Dis. 2013 Oct; 4(10): e848. Published online 2013 Oct 10. doi: 10.1038/cddis.2013.339
PMCID:
PMC3824649
AbstractArticlePDF–4.3M
14.
Essential role of TAK1 in regulating mantle cell lymphoma survival
Daniela Buglio, Sangeetha Palakurthi, Kate Byth, Francisco Vega, Dorin Toader, Jamal Saeh, Sattva S. Neelapu, Anas Younes
Blood. 2012 Jul 12; 120(2): 347–355. Prepublished online 2012 May 30. doi: 10.1182/blood-2011-07-369397
Correction in:
Blood. 2014 Jul 17; 124(3): 463.
PMCID:
PMC3460632
AbstractArticle
15.
Inhibition of Transforming Growth Factor-Activated Kinase 1 (TAK1) Blocks and Reverses Epithelial to Mesenchymal Transition of Mesothelial Cells
Raffaele Strippoli, Ignacio Benedicto, Maria Luisa Perez Lozano, Teijo Pellinen, Pilar Sandoval, Manuel Lopez-Cabrera, Miguel Angel del Pozo
PLoS One. 2012; 7(2): e31492. Published online 2012 Feb 27. doi: 10.1371/journal.pone.0031492
PMCID:
PMC3288041
AbstractArticlePDF–1.4M
16.
Modulation of Pancreatic Cancer Chemoresistance by Inhibition of TAK1
Davide Melisi, Qianghua Xia, Genni Paradiso, Jianhua Ling, Tania Moccia, Carmine Carbone, Alfredo Budillon, James L. Abbruzzese, Paul J. Chiao
J Natl Cancer Inst. 2011 Aug 3; 103(15): 1190–1204. Published online 2011 Jul 8. doi: 10.1093/jnci/djr243
PMCID:
PMC3149044
AbstractArticlePDF–2.6M
17.
TAK1 regulates SCF expression to modulate PKBα activity that protects keratinocytes from ROS-induced apoptosis
C R I Lam, M J Tan, S H Tan, M B Y Tang, P C F Cheung, N S Tan
Cell Death Differ. 2011 Jul; 18(7): 1120–1129. Published online 2011 Jan 14. doi: 10.1038/cdd.2010.182
PMCID:
PMC3131962
AbstractArticlePDF–869K
18.
TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation
Renfang Mao, Yihui Fan, Yonggao Mou, Hong Zhang, Songbin Fu, Jianhua Yang
Cell Signal. Author manuscript; available in PMC 2012 Jan 1.
Published in final edited form as: Cell Signal. 2011 Jan; 23(1): 222–227. Published online 2010 Sep 16. doi: 10.1016/j.cellsig.2010.09.006
PMCID:
PMC2956842
AbstractArticlePDF–1.5M
19.
TAK1-Mediated Serine/Threonine Phosphorylation of Epidermal Growth Factor Receptor via p38/Extracellular Signal-Regulated Kinase: NF-κB-Independent Survival Pathways in Tumor Necrosis Factor Alpha Signaling
Miki Nishimura, Myoung-Sook Shin, Pattama Singhirunnusorn, Shunsuke Suzuki, Miho Kawanishi, Keiichi Koizumi, Ikuo Saiki, Hiroaki Sakurai
Mol Cell Biol. 2009 Oct; 29(20): 5529–5539. Published online 2009 Aug 17. doi: 10.1128/MCB.00375-09
PMCID:
PMC2756876
AbstractArticlePDF–2.1M
20.
Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes
Deepa R Hammaker, David L Boyle, Tomoyuki Inoue, Gary S Firestein
Arthritis Res Ther. 2007; 9(3): R57. Published online 2007 Jun 8. doi: 10.1186/ar2215
PMCID:
PMC2206340
AbstractArticlePDF–732K

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