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Select item 51556871.

Mutations in TBL1X Are Associated With Central Hypothyroidism

Charlotte A. Heinen, Monique Losekoot, Yu Sun, Peter J. Watson, Louise Fairall, Sjoerd D. Joustra, Nitash Zwaveling-Soonawala, Wilma Oostdijk, Erica L. T. van den Akker, Mariëlle Alders, Gijs W. E. Santen, Rick R. van Rijn, Wouter A. Dreschler, Olga V. Surovtseva, Nienke R. Biermasz, Raoul C. Hennekam, Jan M. Wit, John W. R. Schwabe, Anita Boelen, Eric Fliers, A. S. Paul van Trotsenburg

J Clin Endocrinol Metab. 2016 Dec; 101(12): 4564–4573. Published online 2016 Sep 7. doi: 10.1210/jc.2016-2531

PMCID:: PMC5155687

Abstract Article

Select item 99296872.

TBL1X: AT THE CROSSROADS OF TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL REGULATION

Betsy A Pray, Youssef Youssef, Lapo Alinari

Exp Hematol. Author manuscript; available in PMC 2023 Feb 15.

Published in final edited form as: Exp Hematol. 2022 Dec; 116: 18–25. Published online 2022 Oct 4. doi: 10.1016/j.exphem.2022.09.006

PMCID:: PMC9929687

Abstract Article PDF–594K

Select item 85612813.

Transducin b-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma

Youssef Youssef, Vrajesh Karkhanis, Wing Keung Chan, Frankie Jeney, Alessandro Canella, Xiaoli Zhang, Shelby Sloan, Alexander Prouty, JoBeth Helmig-Mason, Liudmyla Tsyba, Walter Hanel, Xuguang Zheng, Pu Zhang, Ji-Hyun Chung, David M. Lucas, Zachary Kauffman, Karilyn Larkin, Anne M. Strohecker, Hatice G. Ozer, Rosa Lapalombella, Hui Zhou, Zijun Y. Xu-Monette, Ken H. Young, Ruolan Han, Elmar Nurmemmedov, Gerard Nuovo, Kami Maddocks, John C. Byrd, Robert A. Baiocchi, Lapo Alinari

Haematologica. 2021 Nov 1; 106(11): 2927–2939. Published online 2020 Sep 14. doi: 10.3324/haematol.2020.268235

PMCID:: PMC8561281

Abstract Article PDF–1.9M

Select item 51730464.

SUMOylation of TBL1 and TBLR1 promotes androgen-independent prostate cancer cell growth

Soo-Yeon Park, Younghwa Na, Mee-Hee Lee, Jae-Sung Seo, Yoo-Hyun Lee, Kyung-Chul Choi, Hyo-Kyoung Choi, Ho-Geun Yoon

Oncotarget. 2016 Jul 5; 7(27): 41110–41122. Published online 2016 Apr 26. doi: 10.18632/oncotarget.9002

PMCID:: PMC5173046

Abstract Article PDF–9.5M

Select item 13779035.

X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats.

M T Bassi, R S Ramesar, B Caciotti, I M Winship, A De Grandi, M Riboni, P L Townes, P Beighton, A Ballabio, G Borsani

Am J Hum Genet. 1999 Jun; 64(6): 1604–1616. doi: 10.1086/302408

PMCID:: PMC1377903

Summary PDF–746K

Select item 45513436.

Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy

Christian Stoy, Aishwarya Sundaram, Marcos Rios Garcia, Xiaoyue Wang, Oksana Seibert, Annika Zota, Susann Wendler, David Männle, Ulf Hinz, Carsten Sticht, Maria Muciek, Norbert Gretz, Adam J Rose, Vera Greiner, Thomas G Hofmann, Andrea Bauer, Jörg Hoheisel, Mauricio Berriel Diaz, Matthias M Gaida, Jens Werner, Tobias Schafmeier, Oliver Strobel, Stephan Herzig

EMBO Mol Med. 2015 Aug; 7(8): 1048–1062. Published online 2015 Jun 13. doi: 10.15252/emmm.201404837

PMCID:: PMC4551343

Abstract Article PDF–2.1M

Select item 41426207.

SUMOylation of GPS2 protein regulates its transcription-suppressing function

Hailian Bi, Shujing Li, Miao Wang, Zhaojun Jia, Alan K. Chang, Pengsha Pang, Huijian Wu

Mol Biol Cell. 2014 Aug 15; 25(16): 2499–2508. doi: 10.1091/mbc.E13-12-0733

PMCID:: PMC4142620

Abstract Article PDF–1.8M

Select item 32324518.

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

Jasmeen Oberoi, Louise Fairall, Peter J. Watson, Ji-Chun Yang, Zsolt Czimmerer, Thorsten Kampmann, Benjamin T. Goult, Jacquie A. Greenwood, John T. Gooch, Bettina C. Kallenberger, Laszlo Nagy, David Neuhaus, John W.R. Schwabe

Nat Struct Mol Biol. Author manuscript; available in PMC 2011 Dec 7.

Published in final edited form as: Nat Struct Mol Biol. 2011 Feb; 18(2): 177–184. Published online 2011 Jan 16. doi: 10.1038/nsmb.1983

PMCID:: PMC3232451

Abstract Article PDF–2.4M

Select item 30678169.

Transducin β-Like Protein 1 Recruits Nuclear Factor κB to the Target Gene Promoter for Transcriptional Activation

Sivakumar Ramadoss, Jiong Li, Xiangming Ding, Khalid Al Hezaimi, Cun-Yu Wang

Mol Cell Biol. 2011 Mar; 31(5): 924–934. Published online 2010 Dec 28. doi: 10.1128/MCB.00576-10

PMCID:: PMC3067816

Abstract Article PDF–1.5M

Select item 999549610.

A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay

Beatrice Alexander-Howden, Li Zhang, Almer M. van der Sloot, Sylvain Tollis, Daniel J. St-Cyr, Frank Sicheri, Adrian P. Bird, Mike Tyers, Matthew J. Lyst

Sci Rep. 2023; 13: 3868. Published online 2023 Mar 8. doi: 10.1038/s41598-023-29915-z

PMCID:: PMC9995496

Abstract Article PDF–2.4M

Select item 541952411.

Function of Multiple Lis-Homology Domain/WD-40 Repeat-Containing Proteins in Feed-Forward Transcriptional Repression by Silencing Mediator for Retinoic and Thyroid Receptor/Nuclear Receptor Corepressor Complexes

Hyo-Kyoung Choi, Kyung-Chul Choi, Hee-Bum Kang, Han-Cheon Kim, Yoo-Hyun Lee, Seungjoo Haam, Hyoung-Gi Park, Ho-Geun Yoon

Mol Endocrinol. May 1, 2008; 22(5): 1093–1104. doi: 10.1210/me.2007-0396

PMCID:: PMC5419524

Abstract Article

Select item 457020912.

SENP2 regulates MMP13 expression in a bladder cancer cell line through SUMOylation of TBL1/TBLR1

Mingyue Tan, Hua Gong, Jun Wang, Le Tao, Dongliang Xu, Erdun Bao, Zhihong Liu, Jianxin Qiu

Sci Rep. 2015; 5: 13996. Published online 2015 Sep 15. doi: 10.1038/srep13996

PMCID:: PMC4570209

Abstract Article PDF–670K

Select item 236461113.

TBL1 and TBLR1 Phosphorylation on Regulated Gene Promoters Overcomes Dual CtBP and NCoR/SMRT Transcriptional Repression Checkpoints

Valentina Perissi, Claudio Scafoglio, Jie Zhang, Kenneth A. Ohgi, David W. Rose, Christopher K. Glass, Michael G. Rosenfeld

Mol Cell. Author manuscript; available in PMC 2008 May 1.

Published in final edited form as: Mol Cell. 2008 Mar 28; 29(6): 755–766. doi: 10.1016/j.molcel.2008.01.020

PMCID:: PMC2364611

Abstract Article PDF–1.3M

Select item 31656914.

A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness

Matthew G. Guenther, William S. Lane, Wolfgang Fischle, Eric Verdin, Mitchell A. Lazar, Ramin Shiekhattar

Genes Dev. 2000 May 1; 14(9): 1048–1057.

PMCID:: PMC316569

Abstract Article PDF–2.1M

Select item 18750015.

Assembly of the SMRT–histone deacetylase 3 repression complex requires the TCP-1 ring complex

Matthew G. Guenther, Jiujiu Yu, Gary D. Kao, Tim J. Yen, Mitchell A. Lazar

Genes Dev. 2002 Dec 15; 16(24): 3130–3135. doi: 10.1101/gad.1037502

PMCID:: PMC187500

Abstract Article PDF–294K

Select item 283317216.

Adamantyl-Substituted Retinoid-Related Molecules Bind Small Heterodimer Partner and Modulate the Sin3A Repressor

Lulu Farhana, Marcia I. Dawson, Mark Leid, Li Wang, David D. Moore, Gang Liu, Zeben Xia, Joseph A. Fontana

Cancer Res. Author manuscript; available in PMC 2010 Mar 5.

Published in final edited form as: Cancer Res. 2007 Jan 1; 67(1): 318–325. doi: 10.1158/0008-5472.CAN-06-2164

PMCID:: PMC2833172

Abstract Article PDF–1.2M

Select item 30203017.

Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3

Jiwen Li, Jin Wang, Jianxiang Wang, Zafar Nawaz, Johnson M. Liu, Jun Qin, Jiemin Wong

EMBO J. 2000 Aug 15; 19(16): 4342–4350. doi: 10.1093/emboj/19.16.4342

PMCID:: PMC302030

Abstract Article PDF–462K

Select item 540241518.

Structure of the MeCP2–TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders

Valdeko Kruusvee, Matthew J. Lyst, Ceitidh Taylor, Žygimantė Tarnauskaitė, Adrian P. Bird, Atlanta G. Cook

Proc Natl Acad Sci U S A. 2017 Apr 18; 114(16): E3243–E3250. Published online 2017 Mar 27. doi: 10.1073/pnas.1700731114

PMCID:: PMC5402415

Abstract Article PDF–1.7M

Select item 239377119.

Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore–microtubule attachment

Sumiyasu Ishii, Yasuhiro Kurasawa, Jiemin Wong, Li-yuan Yu-Lee

Proc Natl Acad Sci U S A. 2008 Mar 18; 105(11): 4179–4184. Published online 2008 Mar 6. doi: 10.1073/pnas.0710140105

PMCID:: PMC2393771

Abstract Article PDF–990K

Select item 53877920.

Reading and Function of a Histone Code Involved in Targeting Corepressor Complexes for Repression

Ho-Geun Yoon, Youngsok Choi, Philip A. Cole, Jiemin Wong

Mol Cell Biol. 2005 Jan; 25(1): 324–335. doi: 10.1128/MCB.25.1.324-335.2005

PMCID:: PMC538779

Abstract Article PDF–629K

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