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Select item 104568761.

Structural basis of telomeric nucleosome recognition by shelterin factor TRF1

Hongmiao Hu, Anne-Marie M. van Roon, George E. Ghanim, Bilal Ahsan, Abraham O. Oluwole, Sew-Yeu Peak-Chew, Carol V. Robinson, Thi Hoang Duong Nguyen

Sci Adv. 2023 Aug; 9(34): eadi4148. Published online 2023 Aug 25. doi: 10.1126/sciadv.adi4148

PMCID:: PMC10456876

Abstract Article PDF–2.0M

Select item 78262882.

Dynamics of TRF1 organizing a single human telomere

Xu Li, Meijie Wang, Wei Zheng, Wei Huang, Zeyu Wang, Kairang Jin, Lin Liu, Zhongbo Yu

Nucleic Acids Res. 2021 Jan 25; 49(2): 760–775. Published online 2020 Dec 21. doi: 10.1093/nar/gkaa1222

PMCID:: PMC7826288

Abstract Article PDF–3.2M

Select item 69819813.

A Novel Tissue and Stem Cell Specific TERF1 Splice Variant Is Downregulated in Tumour Cells

Yousef Ashraf Tawfik Morcos, Gregoire Najjar, Sabine Meessen, Britta Witt, Anca Azoitei, Mukesh Kumar, Gamal Wakileh, Klaus Schwarz, Hubert Schrezenmeier, Friedemann Zengerling, Christian Bolenz, Cagatay Günes

Int J Mol Sci. 2020 Jan; 21(1): 85. Published online 2019 Dec 20. doi: 10.3390/ijms21010085

PMCID:: PMC6981981

Abstract Article PDF–6.4M

Select item 56760564.

Gene therapy with the TRF1 telomere gene rescues decreased TRF1 levels with aging and prolongs mouse health span

Aksinya Derevyanko, Kurt Whittemore, Ralph P. Schneider, Verónica Jiménez, Fàtima Bosch, Maria A. Blasco

Aging Cell. 2017 Dec; 16(6): 1353–1368. Published online 2017 Sep 24. doi: 10.1111/acel.12677

PMCID:: PMC5676056

Abstract Article PDF–2.7M

Select item 51079615.

TRF1 phosphorylation on T271 modulates telomerase-dependent telomere length maintenance as well as the formation of ALT-associated PML bodies

Angus Ho, Florence R. Wilson, Stephanie L. Peragine, Kajaparan Jeyanthan, Taylor R. H. Mitchell, Xu-Dong Zhu

Sci Rep. 2016; 6: 36913. Published online 2016 Nov 14. doi: 10.1038/srep36913

PMCID:: PMC5107961

Abstract Article PDF–1.5M

Select item 37762286.

A Comprehensive Model for the Recognition of Human Telomeres by TRF1

Michael Garton, Charles Laughton

J Mol Biol. 2013 Aug 23; 425(16): 2910–2921. doi: 10.1016/j.jmb.2013.05.005

PMCID:: PMC3776228

Abstract Article

Select item 35908437.

A TRF1-controlled common fragile site containing interstitial telomeric sequences

Nazario Bosco, Titia de Lange

Chromosoma. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Chromosoma. 2012 Oct; 121(5): 465–474. Published online 2012 Jul 13. doi: 10.1007/s00412-012-0377-6

PMCID:: PMC3590843

Abstract Article PDF–2.8M

Select item 28531358.

The human telomeric protein hTRF1 induces telomere-specific nucleosome mobility

Sabrina Pisano, Daniela Leoni, Alessandra Galati, Daniela Rhodes, Maria Savino, Stefano Cacchione

Nucleic Acids Res. 2010 Apr; 38(7): 2247–2255. Published online 2010 Jan 7. doi: 10.1093/nar/gkp1228

PMCID:: PMC2853135

Abstract Article PDF–8.7M

Select item 28126469.

Intrinsic hTRF1fluorescence quenching reveals details of telomere DNA binding activity: Impact of DNA length, structure and position of telomeric repeats

Kambiz Tahmaseb, John J. Turchi

Arch Biochem Biophys. Author manuscript; available in PMC 2011 Jan 15.

Published in final edited form as: Arch Biochem Biophys. 2010 Jan 15; 493(2): 207–212. Published online 2009 Nov 1. doi: 10.1016/j.abb.2009.10.015

PMCID:: PMC2812646

Abstract Article PDF–1.8M

Select item 139063410.

Study on the expression and mutation of human telomeric repeat binding factor (hTRF1) in 10 malignant hematopoietic cell lines

Jie Sun, He Huang, Yuan-yuan Zhu, Jian-ping Lan, Jing-yuan Li, Xiao-yu Lai, Jian Yu

J Zhejiang Univ Sci B. 2005 Dec; 6(12): 1141–1147. Published online 2005 Nov 22. doi: 10.1631/jzus.2005.B1141

PMCID:: PMC1390634

Abstract Article PDF–390K

Select item 136376111.

A study of the relationship between expression level of TRF1 protein and telomerase activity in human acute leukemia

Ji-min Shi, He Huang, Qiao-fang Chen, Mao-fang Lin

J Zhejiang Univ Sci B. 2006 Feb; 7(2): 154–158. Published online 2006 Jan 19. doi: 10.1631/jzus.2006.B0154

PMCID:: PMC1363761

Abstract Article PDF–204K

Select item 950095612.

In Vitro Characterization of the Physical Interactions between the Long Noncoding RNA TERRA and the Telomeric Proteins TRF1 and TRF2

Patricia L. Abreu, Yong Woo Lee, Claus M. Azzalin

Int J Mol Sci. 2022 Sep; 23(18): 10463. Published online 2022 Sep 9. doi: 10.3390/ijms231810463

PMCID:: PMC9500956

Abstract Article PDF–2.3M

Select item 898800713.

Compartmentalization of Telomeres through DNA-scaffolded Phase Separation

Amanda Jack, Yoonji Kim, Amy R. Strom, Daniel S.W. Lee, Byron Williams, Jeffrey M. Schaub, Elizabeth H. Kellogg, Ilya J. Finkelstein, Luke S. Ferro, Ahmet Yildiz, Clifford P. Brangwynne

Dev Cell. Author manuscript; available in PMC 2022 Apr 24.

Published in final edited form as: Dev Cell. 2022 Jan 24; 57(2): 277–290.e9. doi: 10.1016/j.devcel.2021.12.017

PMCID:: PMC8988007

Abstract Article PDF–2.6M

Select item 764697914.

TERF1 downregulation promotes the migration and invasion of the PC3 prostate cancer cell line as a target of miR-155

Wei Chen, Li-Na He, Yong Liang, Xiang Zeng, Cui-Ping Wu, Ming-Qiang Su, Yang Cheng, Jian-Hui Liu

Mol Med Rep. 2020 Dec; 22(6): 5209–5218. Published online 2020 Oct 21. doi: 10.3892/mmr.2020.11623

PMCID:: PMC7646979

Abstract Article PDF–1.2M

Select item 733508015.

Persistent telomere cohesion protects aged cells from premature senescence

Kameron Azarm, Amit Bhardwaj, Eugenie Kim, Susan Smith

Nat Commun. 2020; 11: 3321. Published online 2020 Jul 3. doi: 10.1038/s41467-020-17133-4

PMCID:: PMC7335080

Abstract Article PDF–4.6M

Select item 676737216.

Condensin II subunit NCAPH2 associates with shelterin protein TRF1 and is required for telomere stability

Heather A. Wallace, Vibhuti Rana, Huy Q. Nguyen, Giovanni Bosco

J Cell Physiol. 2019 Nov; 234(11): 20755–20768. Published online 2019 Apr 26. doi: 10.1002/jcp.28681

PMCID:: PMC6767372

Abstract Article PDF–3.5M

Select item 580884517.

TRF1 participates in chromosome end protection by averting TRF2-dependent telomeric R-loops

Yong Woo Lee, Rajika Arora, Harry Wischnewski, Claus M. Azzalin

Nat Struct Mol Biol. Author manuscript; available in PMC 2018 Jul 22.

Published in final edited form as: Nat Struct Mol Biol. 2018 Feb; 25(2): 147–153. Published online 2018 Jan 22. doi: 10.1038/s41594-017-0021-5

PMCID:: PMC5808845

Abstract Article PDF–3.3M

Select item 554180618.

Expression of Telomere Repeat Binding Factor 1 and TRF2 in Prostate Cancer and Correlation with Clinical Parameters

Wei Chen, Yong Wang, Fei Li, Wei Lin, Yong Liang, Zhiwei Ma

Biomed Res Int. 2017; 2017: 9764752. Published online 2017 Jul 20. doi: 10.1155/2017/9764752

PMCID:: PMC5541806

Abstract Article PDF–1.2M

Select item 549780619.

Rho GDP‐dissociation inhibitor α is a potential prognostic biomarker and controls telomere regulation in colorectal cancer

Dandan Huang, Weisi Lu, Shaomin Zou, Huaiming Wang, Yuanling Jiang, Xiya Zhang, Pengqing Li, Zhou Songyang, Lei Wang, Jianping Wang, Junjiu Huang, Lekun Fang

Cancer Sci. 2017 Jul; 108(7): 1293–1302. Published online 2017 May 31. doi: 10.1111/cas.13259

PMCID:: PMC5497806

Abstract Article PDF–2.6M

Select item 529127020.

Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA–DNA pairing

Jiangguo Lin, Preston Countryman, Haijiang Chen, Hai Pan, Yanlin Fan, Yunyun Jiang, Parminder Kaur, Wang Miao, Gisele Gurgel, Changjiang You, Jacob Piehler, Neil M. Kad, Robert Riehn, Patricia L. Opresko, Susan Smith, Yizhi Jane Tao, Hong Wang

Nucleic Acids Res. 2016 Jul 27; 44(13): 6363–6376. Published online 2016 Jun 13. doi: 10.1093/nar/gkw518