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Select item 50697861.

Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells

Lin Zhang, Gan Wang, Shiwen Chen, Jun Ding, Shiming Ju, Heli Cao, Hengli Tian

World J Surg Oncol. 2016; 14: 267. Published online 2016 Oct 19. doi: 10.1186/s12957-016-1018-y

PMCID:: PMC5069786

Abstract Article PDF–1.1M

Select item 46043442.

Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteins

Sandra Vidak, Nard Kubben, Thomas Dechat, Roland Foisner

Genes Dev. 2015 Oct 1; 29(19): 2022–2036. doi: 10.1101/gad.263939.115

PMCID:: PMC4604344

Abstract Article PDF–1.3M

Select item 20637933.

Lamina-associated polypeptide 2α regulates cell cycle progression and differentiation via the retinoblastoma–E2F pathway

Daniela Dorner, Sylvia Vlcek, Nicole Foeger, Andreas Gajewski, Christian Makolm, Josef Gotzmann, Christopher J. Hutchison, Roland Foisner

J Cell Biol. 2006 Apr 10; 173(1): 83–93. doi: 10.1083/jcb.200511149

PMCID:: PMC2063793

Abstract Article PDF–3.9M

Select item 11708184.

Detergent-salt resistance of LAP2alpha in interphase nuclei and phosphorylation-dependent association with chromosomes early in nuclear assembly implies functions in nuclear structure dynamics.

T Dechat, J Gotzmann, A Stockinger, C A Harris, M A Talle, J J Siekierka, R Foisner

EMBO J. 1998 Aug 17; 17(16): 4887–4902. doi: 10.1093/emboj/17.16.4887

PMCID:: PMC1170818

Summary PDF–876K

Select item 4322095.

Bioassay determinations of thymopoietin and thymic hormone levels in human plasma.

J J Twomey, G Goldstein, V M Lewis, P M Bealmear, R A Good

Proc Natl Acad Sci U S A. 1977 Jun; 74(6): 2541–2545. doi: 10.1073/pnas.74.6.2541

PMCID:: PMC432209

Summary Page Browse PDF–907K

Select item 1252636.

Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA

Mengli Cai, Ying Huang, Rodolfo Ghirlando, Katherine L. Wilson, Robert Craigie, G.Marius Clore

EMBO J. 2001 Aug 15; 20(16): 4399–4407. doi: 10.1093/emboj/20.16.4399

PMCID:: PMC125263

Abstract Article PDF–359K

Select item 441857.

Three distinct human thymopoietins are derived from alternatively spliced mRNAs.

C A Harris, P J Andryuk, S Cline, H K Chan, A Natarajan, J J Siekierka, G Goldstein

Proc Natl Acad Sci U S A. 1994 Jul 5; 91(14): 6283–6287. doi: 10.1073/pnas.91.14.6283

PMCID:: PMC44185

Summary Page Browse PDF–1.9M

Select item 36899548.

High Mobility Group Protein N5 (HMGN5) and Lamina-associated Polypeptide 2α (LAP2α) Interact and Reciprocally Affect Their Genome-wide Chromatin Organization

Shaofei Zhang, Dustin E. Schones, Cedric Malicet, Mark Rochman, Ming Zhou, Roland Foisner, Michael Bustin

J Biol Chem. 2013 Jun 21; 288(25): 18104–18109. Published online 2013 May 14. doi: 10.1074/jbc.C113.469544

PMCID:: PMC3689954

Abstract Article PDF–1.6M

Select item 20639369.

Nucleoplasmic LAP2α–lamin A complexes are required to maintain a proliferative state in human fibroblasts

Vanja Pekovic, Jens Harborth, Jos L.V. Broers, Frans C.S. Ramaekers, Baziel van Engelen, Martin Lammens, Thomas von Zglinicki, Roland Foisner, Chris Hutchison, Ewa Markiewicz

J Cell Biol. 2007 Jan 15; 176(2): 163–172. doi: 10.1083/jcb.200606139

PMCID:: PMC2063936

Abstract Article PDF–1.8M

Select item 456598010.

Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria

Alexandre Chojnowski, Peh Fern Ong, Esther SM Wong, John SY Lim, Rafidah A Mutalif, Raju Navasankari, Bamaprasad Dutta, Henry Yang, Yi Y Liow, Siu K Sze, Thomas Boudier, Graham D Wright, Alan Colman, Brian Burke, Colin L Stewart, Oliver Dreesen

eLife. 2015; 4: e07759. Published online 2015 Aug 27. doi: 10.7554/eLife.07759

PMCID:: PMC4565980

Abstract Article PDF–4.3M

Select item 217264011.

HA95 and LAP2β mediate a novel chromatin–nuclear envelope interaction implicated in initiation of DNA replication

Sandra Martins, Sissel Eikvar, Kazuhiro Furukawa, Philippe Collas

J Cell Biol. 2003 Jan 20; 160(2): 177–188. doi: 10.1083/jcb.200210026

PMCID:: PMC2172640

Abstract Article PDF–1.7M

Select item 13864212.

Lamin A/C Binding Protein LAP2α Is Required for Nuclear Anchorage of Retinoblastoma Protein

Ewa Markiewicz, Thomas Dechat, Roland Foisner, Roy. A Quinlan, Christopher J. Hutchison

Mol Biol Cell. 2002 Dec; 13(12): 4401–4413. doi: 10.1091/mbc.E02-07-0450

PMCID:: PMC138642

Abstract Article PDF–899K

Select item 924382013.

LncRNA TMPO-AS1 promotes esophageal squamous cell carcinoma progression by forming biomolecular condensates with FUS and p300 to regulate TMPO transcription

Xiao-Jing Luo, Ming-Ming He, Jia Liu, Jia-Bo Zheng, Qi-Nian Wu, Yan-Xing Chen, Qi Meng, Kong-Jia Luo, Dong-Liang Chen, Rui-Hua Xu, Zhao-Lei Zeng, Ze-Xian Liu, Hui-Yan Luo

Exp Mol Med. 2022 Jun; 54(6): 834–847. Published online 2022 Jun 27. doi: 10.1038/s12276-022-00791-3

PMCID:: PMC9243820

Abstract Article PDF–7.0M

Select item 637907814.

LAP2 Proteins Chaperone GLI1 Movement Between Lamina and Chromatin to Regulate Transcription

Amar N. Mirza, Siegen A. McKellar, Nicole M. Urman, Alexander S. Brown, Tyler Hollmig, Sumaira Z. Aasi, Anthony E. Oro

Cell. Author manuscript; available in PMC 2020 Jan 10.

Published in final edited form as: Cell. 2019 Jan 10; 176(1-2): 198–212.e15. Published online 2018 Nov 29. doi: 10.1016/j.cell.2018.10.054

PMCID:: PMC6379078

Abstract Article PDF–3.4M

Select item 275880715.

Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases

Kathryn E. Tifft, Katherine A. Bradbury, Katherine L. Wilson

J Cell Sci. 2009 Oct 15; 122(20): 3780–3790. Published online 2009 Sep 29. doi: 10.1242/jcs.048397

PMCID:: PMC2758807

Abstract Article

Select item 313556516.

Concordant and opposite roles of DNA-PK and the "facilitator of chromatin transcription" (FACT) in DNA repair, apoptosis and necrosis after cisplatin

Janna Sand-Dejmek, Guillaume Adelmant, Bijan Sobhian, Anne S Calkins, Jarrod Marto, Dirk J Iglehart, Jean-Bernard Lazaro

Mol Cancer. 2011; 10: 74. Published online 2011 Jun 16. doi: 10.1186/1476-4598-10-74

PMCID:: PMC3135565

Abstract Article PDF–1011K

Select item 501618317.

FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator)

Wei Shao, Kristina Zumer, Koh Fujinaga, B. Matija Peterlin

J Biol Chem. 2016 Aug 19; 291(34): 17953–17963. Published online 2016 Jun 30. doi: 10.1074/jbc.M116.724401

PMCID:: PMC5016183

Abstract Article PDF–1.0M

Select item 840391118.

Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of three proteins from SARS-CoV-2

Moriya Slavin, Joanna Zamel, Keren Zohar, Tsiona Eliyahu, Merav Braitbard, Esther Brielle, Leah Baraz, Miri Stolovich-Rain, Ahuva Friedman, Dana G. Wolf, Alexander Rouvinski, Michal Linial, Dina Schneidman-Duhovny, Nir Kalisman

Proc Natl Acad Sci U S A. 2021 Aug 24; 118(34): e2103554118. Published online 2021 Aug 9. doi: 10.1073/pnas.2103554118

PMCID:: PMC8403911

Abstract Article PDF–1.9M

Select item 744247419.

DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination

Syed Feroj Ahmed, Lori Buetow, Mads Gabrielsen, Sergio Lilla, Chatrin Chatrin, Gary J. Sibbet, Sara Zanivan, Danny T. Huang

Sci Adv. 2020 Aug; 6(34): eabc0629. Published online 2020 Aug 21. doi: 10.1126/sciadv.abc0629

PMCID:: PMC7442474

Abstract Article PDF–2.4M

Select item 620539620.

E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs

Enguang Bi, Rong Li, Laura C. Bover, Haiyan Li, Pan Su, Xingzhe Ma, Chunjian Huang, Qiang Wang, Lintao Liu, Maojie Yang, Zhijuan Lin, Jianfei Qian, Weijun Fu, Yong-Jun Liu, Qing Yi

J Clin Invest. 2018 Nov 1; 128(11): 4821–4831. Published online 2018 Oct 2. doi: 10.1172/JCI121421