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Select item 110670251.

TRAF3 loss-of-function reveals the noncanonical NF-κB pathway as a therapeutic target in diffuse large B cell lymphoma

Michael Y. Li, Lauren C. Chong, Gerben Duns, Andrew Lytle, Bruce Woolcock, Aixiang Jiang, Adèle Telenius, Susana Ben-Neriah, Waqas Nawaz, Graham W. Slack, Ingrid Elisia, Elena Viganò, Tomohiro Aoki, Shannon Healy, Gerald Krystal, Leandro Venturutti, David W. Scott, Christian Steidl

Proc Natl Acad Sci U S A. 2024 Apr 30; 121(18): e2320421121. Published online 2024 Apr 25. doi: 10.1073/pnas.2320421121

PMCID:: PMC11067025

Abstract Article PDF–4.2M

Select item 105572792.

Effects of TRAF3 on the proliferation and migration of lung adenocarcinoma depend partly on pyroptosis

Wangjia Wang, Shiqi Wang, Min Wang, Yamei Ma, Wanting Hu, Binsha Wu, Chichi Li, Dan Zhang

BMC Cancer. 2023; 23: 942. Published online 2023 Oct 5. doi: 10.1186/s12885-023-11468-z

PMCID:: PMC10557279

Abstract Article PDF–2.5M

Select item 99500633.

TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion

Wenwen Zheng, Zhenbang Zhou, Yajuan Rui, Runxin Ye, Fengyan Xia, Fei Guo, Xiaoman Liu, Jiaming Su, Meng Lou, Xiao-Fang Yu

Signal Transduct Target Ther. 2023; 8: 79. Published online 2023 Feb 24. doi: 10.1038/s41392-022-01287-2

PMCID:: PMC9950063

Abstract Article PDF–5.5M

Select item 79679194.

Hypoxic colorectal cancer‐derived extracellular vesicles deliver microRNA‐361‐3p to facilitate cell proliferation by targeting TRAF3 via the noncanonical NF‐κB pathways

Jie Li, Peng Yang, Fangyu Chen, Yuqian Tan, Changzhi Huang, Hengyang Shen, Chaofan Peng, Yifei Feng, Yueming Sun

Clin Transl Med. 2021 Mar; 11(3): e349. Published online 2021 Mar 17. doi: 10.1002/ctm2.349

PMCID:: PMC7967919

Abstract Article PDF–15M

Select item 79472185.

Rv3722c Promotes Mycobacterium tuberculosis Survival in Macrophages by Interacting With TRAF3

Yingying Lei, Xiaojian Cao, Weize Xu, Bing Yang, Yangyang Xu, Wei Zhou, Shuang Dong, Qijun Wu, Khaista Rahman, Rohit Tyagi, Shuhong Zhao, Xi Chen, Gang Cao

Front Cell Infect Microbiol. 2021; 11: 627798. Published online 2021 Feb 25. doi: 10.3389/fcimb.2021.627798

PMCID:: PMC7947218

Abstract Article PDF–2.3M

Select item 71170126.

TRAF3 signaling: Competitive binding and evolvability of adaptive viral molecular mimicry

Emine Guven-Maiorov, Ozlem Keskin, Attila Gursoy, Carter VanWaes, Zhong Chen, Chung-Jung Tsai, Ruth Nussinov

Biochim Biophys Acta Gen Subj. 2016 Nov; 1860(11): 2646–2655. Published online 2016 May 18. doi: 10.1016/j.bbagen.2016.05.021

PMCID:: PMC7117012

Abstract Article PDF–1.3M

Select item 61658877.

TRAF3 as a Multifaceted Regulator of B Lymphocyte Survival and Activation

Gail A. Bishop, Laura L. Stunz, Bruce S. Hostager

Front Immunol. 2018; 9: 2161. Published online 2018 Sep 24. doi: 10.3389/fimmu.2018.02161

PMCID:: PMC6165887

Abstract Article PDF–706K

Select item 46131458.

Roles of TRAF3 in T cells: many surprises

Zuoan Yi, Alicia M Wallis, Gail A Bishop

Cell Cycle. 2015 Apr 15; 14(8): 1156–1163. Published online 2015 Feb 27. doi: 10.1080/15384101.2015.1021524

PMCID:: PMC4613145

Abstract Article PDF–123K

Select item 41117559.

The TRAF3 adaptor protein drives proliferation of anaplastic large cell lymphoma cells by regulating multiple signaling pathways

Israel Muro, Gloria Fang, Kacie A Gardella, Indra M Mahajan, Casey W Wright

Cell Cycle. 2014 Jun 15; 13(12): 1918–1927. Published online 2014 Apr 16. doi: 10.4161/cc.28895

PMCID:: PMC4111755

Abstract Article PDF–2.1M

Select item 403636910.

Activation-induced Tumor Necrosis Factor Receptor-associated Factor 3 (Traf3) Alternative Splicing Controls the Noncanonical Nuclear Factor κB Pathway and Chemokine Expression in Human T Cells

Monika Michel, Ilka Wilhelmi, Astrid-Solveig Schultz, Marco Preussner, Florian Heyd

J Biol Chem. 2014 May 9; 289(19): 13651–13660. Published online 2014 Mar 26. doi: 10.1074/jbc.M113.526269

PMCID:: PMC4036369

Abstract Article PDF–1.7M

Select item 399916911.

Roles for TNF-Receptor Associated Factor 3 (TRAF3) in Lymphocyte Functions

Zuoan Yi, Wai Wai Lin, Laura L. Stunz, Gail A. Bishop

Cytokine Growth Factor Rev. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Cytokine Growth Factor Rev. 2014 Apr; 25(2): 147–156. Published online 2013 Dec 25. doi: 10.1016/j.cytogfr.2013.12.002

PMCID:: PMC3999169

Abstract Article PDF–596K

Select item 320229912.

Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions

Joanne M. Hildebrand, Zuoan Yi, Claire M. Buchta, Jayakumar Poovassery, Laura L. Stunz, Gail A. Bishop

Immunol Rev. Author manuscript; available in PMC 2012 Nov 1.

Published in final edited form as: Immunol Rev. 2011 Nov; 244(1): 55–74. doi: 10.1111/j.1600-065X.2011.01055.x

PMCID:: PMC3202299

Abstract Article PDF–859K

Select item 226571613.

Epstein-Barr virus latent membrane protein-1 (LMP-1) 30-bp deletion and Xho I-loss is associated with type III nasopharyngeal carcinoma in Malaysia

Hui Shien See, Yoke Yeow Yap, Wai Kien Yip, Heng Fong Seow

World J Surg Oncol. 2008; 6: 18. Published online 2008 Feb 15. doi: 10.1186/1477-7819-6-18

PMCID:: PMC2265716

Abstract Article PDF–358K

Select item 223406014.

The LMP1 oncogene of EBV activates PERK and the unfolded protein response to drive its own synthesis

Dong Yun Lee, Bill Sugden

Blood. 2008 Feb 15; 111(4): 2280–2289. Prepublished online 2007 Nov 27. doi: 10.1182/blood-2007-07-100032

PMCID:: PMC2234060

Abstract Article

Select item 1050135615.

Circular RNA SMARCA5 inhibits cholangiocarcinoma via microRNA-95-3p/tumor necrosis factor receptor associated factor 3 axis

Guangxin Wang, Xia Gao, Zhijun Sun, Tianyou He, Chaogang Huang, Shouwei Li, Haocheng Long

Anticancer Drugs. 2023 Oct; 34(9): 1002–1009. Published online 2023 Jan 24. doi: 10.1097/CAD.0000000000001487

PMCID:: PMC10501356

Abstract Article PDF–1.1M

Select item 1013090516.

TRAF3–EWSR1 signaling axis acts as a checkpoint on germinal center responses

Yanchuan Li, Lele Zhu, Chun-Jung Ko, Jin-Young Yang, Hongjiao Wang, Ganiraju Manyam, Jing Wang, Xuhong Cheng, Shuli Zhao, Zuliang Jie

J Exp Med. 2023 Aug 7; 220(8): e20221483. Published online 2023 Apr 25. doi: 10.1084/jem.20221483

Correction in:: J Exp Med. 2023 Aug 7; 220(8): e2022148307122023c.

PMCID:: PMC10130905

Abstract Article PDF–6.2M

Select item 826224417.

Brief Research Report Regional Difference in TRAF2 and TRAF3 Gene Mutations in Colon Cancers

Seong Won Moon, Hyun Ji Son, Eun Ji Choi, Nam Jin Yoo, Sug Hyung Lee

Pathol Oncol Res. 2021; 27: 625438. Published online 2021 Apr 14. doi: 10.3389/pore.2021.625438

PMCID:: PMC8262244

Abstract Article PDF–1.8M

Select item 793786918.

Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1

Zhihai Zhou, Yuan Sun, Jingya Xu, Xiaoyu Tang, Ling Zhou, Qianniu Li, Tian Lan, Jingyun Ma

Front Immunol. 2021; 12: 573078. Published online 2021 Feb 22. doi: 10.3389/fimmu.2021.573078

PMCID:: PMC7937869

Abstract Article PDF–2.8M

Select item 725723319.

TRAF3 can interact with GMEB1 and modulate its anti-apoptotic function

George Kotsaris, Despoina Kerselidou, Dimitrios Koutsoubaris, Elena Constantinou, George Malamas, Dimitrios A. Garyfallos, Eudoxia G. Ηatzivassiliou

J Biol Res (Thessalon) 2020 Dec; 27: 7. Published online 2020 May 29. doi: 10.1186/s40709-020-00117-2

PMCID:: PMC7257233

Abstract Article PDF–978K

Select item 700296620.

SMAC mimetic birinapant inhibits hepatocellular carcinoma growth by activating the cIAP1/TRAF3 signaling pathway

Jun Ding, Daming Qin, Yong Zhang, Qinghe Li, Yi Li, Jinmao Li

Mol Med Rep. 2020 Mar; 21(3): 1251–1257. Published online 2020 Jan 3. doi: 10.3892/mmr.2020.10908

PMCID:: PMC7002966

Abstract Article PDF–1012K

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PMC Links for Gene (Select 7187) (188)
PMC
deubiquitinase MYSM1 isoform X4 [Homo sapiens]
deubiquitinase MYSM1 isoform X4 [Homo sapiens]
gi|2217263597|ref|XP_047299674.1|

Protein
TNF receptor-associated factor 3 isoform 1 [Homo sapiens]
TNF receptor-associated factor 3 isoform 1 [Homo sapiens]
gi|22027616|ref|NP_003291.2|

Protein
Homo sapiens zinc finger CCHC-type containing 2 (ZCCHC2), transcript variant 1, ...
Homo sapiens zinc finger CCHC-type containing 2 (ZCCHC2), transcript variant 1, mRNA
gi|1653962072|ref|NM_017742.6|

Nucleotide
RecName: Full=G-protein coupled receptor 52
RecName: Full=G-protein coupled receptor 52
gi|76803659|sp|Q9Y2T5.2|GPR52_HUMAN

Protein

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