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Select item 107352241.

The lncRNA Malat1 inhibits miR-15/16 to enhance cytotoxic T cell activation and memory cell formation

Benjamin D Wheeler, John D Gagnon, Wandi S Zhu, Priscila Muñoz-Sandoval, Simon K Wong, Dimitre S Simeonov, Zhongmei Li, Rachel DeBarge, Matthew H Spitzer, Alexander Marson, K Mark Ansel

eLife. 2023; 12: RP87900. Published online 2023 Dec 21. doi: 10.7554/eLife.87900

PMCID:: PMC10735224

Abstract Article PDF–9.0M

Select item 106186552.

Targeted Inhibition of lncRNA Malat1 Alters the Tumor Immune Microenvironment in Preclinical Syngeneic Mouse Models of Triple-Negative Breast Cancer

Oluwatoyosi Adewunmi, Yichao Shen, Xiang H.-F. Zhang, Jeffrey M. Rosen

Cancer Immunol Res. 2023 Nov 1; 11(11): 1462–1479. Published online 2023 Aug 21. doi: 10.1158/2326-6066.CIR-23-0045

PMCID:: PMC10618655

Abstract Article PDF–13M

Select item 103109173.

Mesenchymal stem cell-derived exosome alleviates sepsis- associated acute liver injury by suppressing MALAT1 through microRNA-26a-5p: an innovative immunopharmacological intervention and therapeutic approach for sepsis

Jizhen Cai, Da Tang, Xiao Hao, Enyi Liu, Wenbo Li, Jian Shi

Front Immunol. 2023; 14: 1157793. Published online 2023 Jun 15. doi: 10.3389/fimmu.2023.1157793

PMCID:: PMC10310917

Abstract Article PDF–21M

Select item 100797264.

Fate mapping RNA-sequencing reveal Malat1 regulates Sca1⁺ progenitor cells to vascular smooth muscle cells transition in vascular remodeling

Lingxia Lyu, Zhoubin Li, Zuoshi Wen, Yongchun He, Xuliang Wang, Liujun Jiang, Xuhao Zhou, Chengchen Huang, Yutao Wu, Ting Chen, Xiaogang Guo

Cell Mol Life Sci. 2023 May; 80(5): 118. Published online 2023 Apr 6. doi: 10.1007/s00018-023-04762-3

PMCID:: PMC10079726

Abstract Article PDF–11M

Select item 99043625.

LncRNA MALAT1 mediates osteogenic differentiation in osteoporosis by regulating the miR-485-5p/WNT7B axis

Yuan Zhou, Zhuo Xu, Yuanyi Wang, Qiang Song, Ruofeng Yin

Front Endocrinol (Lausanne) 2022; 13: 922560. Published online 2023 Jan 24. doi: 10.3389/fendo.2022.922560

PMCID:: PMC9904362

Abstract Article PDF–18M

Select item 94648216.

Malat1 deficiency prevents hypoxia-induced lung dysfunction by protecting the access to alveoli

Sandrine Sallé-Lefort, Stéphanie Miard, Cyndi Henry, Christian Arias-Reyes, François Marcouiller, Marie-Josée Beaulieu, Sophie Aubin, Ariane Lechasseur, Éric Jubinville, David Marsolais, Mathieu C. Morissette, Vincent Joseph, Jorge Soliz, Ynuk Bossé, Frédéric Picard

Front Physiol. 2022; 13: 949378. Published online 2022 Aug 29. doi: 10.3389/fphys.2022.949378

PMCID:: PMC9464821

Abstract Article PDF–2.2M

Select item 93672217.

High-fat diet aggravates colitis via mesenteric adipose tissue derived exosome metastasis-associated lung adenocarcinoma transcript 1

Dong Chen, Miao-Miao Lu, Jin-Hai Wang, Yue Ren, Ling-Ling Xu, Wei-Xin Cheng, Sai-Sai Wang, Xiao-Lin Li, Xiao-Fei Cheng, Jian-Guo Gao, Farhin Shaheed Kalyani, Xi Jin

World J Gastroenterol. 2022 Aug 7; 28(29): 3838–3853. Published online 2022 Aug 7. doi: 10.3748/wjg.v28.i29.3838

PMCID:: PMC9367221

Abstract Article PDF–16M

Select item 92410538.

Ablation of long noncoding RNA MALAT1 activates antioxidant pathway and alleviates sepsis in mice

Jingshu Chen, Shu Tang, Sui Ke, James J. Cai, Daniel Osorio, Andrei Golovko, Benjamin Morpurgo, Shaodong Guo, Yuxiang Sun, Melanie Winkle, George A. Calin, Yanan Tian

Redox Biol. 2022 Aug; 54: 102377. Published online 2022 Jun 18. doi: 10.1016/j.redox.2022.102377

PMCID:: PMC9241053

Abstract Article PDF–4.9M

Select item 88349009.

Exosomal MALAT1 Derived from High Glucose-Treated Macrophages Up-Regulates Resistin Expression via miR-150-5p Downregulation

Kou-Gi Shyu, Bao-Wei Wang, Wei-Jen Fang, Chun-Ming Pan, Chiu-Mei Lin

Int J Mol Sci. 2022 Feb; 23(3): 1095. Published online 2022 Jan 20. doi: 10.3390/ijms23031095

PMCID:: PMC8834900

Abstract Article PDF–2.2M

Select item 793783310.

The lncRNA Malat1 regulates microvascular function after myocardial infarction in mice via miR-26b-5p/Mfn1 axis-mediated mitochondrial dynamics

Yuqiong Chen, Su Li, Yan Zhang, Mengshen Wang, Xinyan Li, Shuang Liu, Dengyue Xu, Yandong Bao, Pengyu Jia, Nan Wu, Yao Lu, Dalin Jia

Redox Biol. 2021 May; 41: 101910. Published online 2021 Feb 22. doi: 10.1016/j.redox.2021.101910

PMCID:: PMC7937833

Abstract Article PDF–23M

Select item 723185211.

Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells

James P. Hewitson, Katie A. West, Kylie R. James, Gulab Fatima Rani, Nidhi Dey, Audrey Romano, Najmeeyah Brown, Sarah A. Teichmann, Paul M. Kaye, Dimitris Lagos

J Immunol. 2020 Jun 1; 204(11): 2949–2960. Published online 2020 Apr 22. doi: 10.4049/jimmunol.1900940

PMCID:: PMC7231852

Abstract Article PDF–1.7M

Select item 653347812.

EPC‐derived exosomes promote osteoclastogenesis through LncRNA‐MALAT1

Yigong Cui, Shenglong Fu, Dong Sun, Junchao Xing, Tianyong Hou, Xuehui Wu

J Cell Mol Med. 2019 Jun; 23(6): 3843–3854. Published online 2019 Apr 25. doi: 10.1111/jcmm.14228

PMCID:: PMC6533478

Abstract Article PDF–1.4M

Select item 633343213.

Long noncoding RNA Malat1 is not essential for T cell development and response to LCMV infection

Yingpeng Yao, Wenhui Guo, Jingjing Chen, Pingting Guo, Guotao Yu, Juanjuan Liu, Fang Wang, Jingjing Liu, Menghao You, Tianyan Zhao, Youmin Kang, Xi Ma, Shuyang Yu

RNA Biol. 2018; 15(12): 1477–1486. Published online 2018 Dec 4. doi: 10.1080/15476286.2018.1551705

PMCID:: PMC6333432

Abstract Article PDF–2.8M

Select item 609915414.

The Long Noncoding RNA MALAT1 Induces Tolerogenic Dendritic Cells and Regulatory T Cells via miR155/Dendritic Cell-Specific Intercellular Adhesion Molecule-3 Grabbing Nonintegrin/IL10 Axis

Jian Wu, Hanlu Zhang, Yang Zheng, Xiangyuan Jin, Mingyang Liu, Shuang Li, Qi Zhao, Xianglan Liu, Yongshun Wang, Ming Shi, Shengnan Zhang, Jinwei Tian, Yong Sun, Maomao Zhang, Bo Yu

Front Immunol. 2018; 9: 1847. Published online 2018 Aug 13. doi: 10.3389/fimmu.2018.01847

Correction in:: Front Immunol. 2020; 11: 582491.

PMCID:: PMC6099154

Abstract Article PDF–4.5M

Select item 603236915.

Long Non-Coding RNA Malat1 Regulates Angiogenesis in Hindlimb Ischemia

Xuejing Zhang, Xuelian Tang, Milton H. Hamblin, Ke-Jie Yin

Int J Mol Sci. 2018 Jun; 19(6): 1723. Published online 2018 Jun 11. doi: 10.3390/ijms19061723

PMCID:: PMC6032369

Abstract Article PDF–2.8M

Select item 594498716.

Loss of Malat1 does not modify age- or diet-induced adipose tissue accretion and insulin resistance in mice

Sophie Carter, Stéphanie Miard, Louise Boivin, Sandrine Sallé-Lefort, Frédéric Picard

PLoS One. 2018; 13(5): e0196603. Published online 2018 May 10. doi: 10.1371/journal.pone.0196603

PMCID:: PMC5944987

Abstract Article PDF–5.1M

Select item 584666117.

Cognitive improvement following ischemia/reperfusion injury induced by voluntary running-wheel exercise is associated with LncMALAT1-mediated apoptosis inhibition

Jin-Lin Shang, Qing Cheng, Sheng-Jie Duan, Lu Li, Li-Ya Jia

Int J Mol Med. 2018 May; 41(5): 2715–2723. Published online 2018 Feb 12. doi: 10.3892/ijmm.2018.3484

PMCID:: PMC5846661

Abstract Article PDF–863K

Select item 535869418.

The role of lncRNA MALAT1 in the regulation of hepatocyte proliferation during liver regeneration

Cuicui Li, Lei Chang, Zhiquan Chen, Zhongzhong Liu, Yanfeng Wang, Qifa Ye

Int J Mol Med. 2017 Feb; 39(2): 347–356. Published online 2017 Jan 11. doi: 10.3892/ijmm.2017.2854

PMCID:: PMC5358694

Abstract Article PDF–1.4M

Select item 532061019.

Long Noncoding RNA Malat1 Regulates Cerebrovascular Pathologies in Ischemic Stroke

Xuejing Zhang, Xuelian Tang, Kai Liu, Milton H. Hamblin, Ke-Jie Yin

J Neurosci. 2017 Feb 15; 37(7): 1797–1806. doi: 10.1523/JNEUROSCI.3389-16.2017

PMCID:: PMC5320610

Abstract Article PDF–3.9M

Select item 476901120.

Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in Mice

Tim Peters, Steffie Hermans-Beijnsberger, Abdelaziz Beqqali, Nicole Bitsch, Shinichi Nakagawa, Kannanganattu V. Prasanth, Leon J. de Windt, Ralph J. van Oort, Stephane Heymans, Blanche Schroen

PLoS One. 2016; 11(2): e0150236. Published online 2016 Feb 26. doi: 10.1371/journal.pone.0150236

PMCID:: PMC4769011

Abstract Article PDF–1.3M

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PMC Links for Gene (Select 72289) (87)
PMC
Hydantoinase B/oxoprolinase domain-containing protein [Caenorhabditis elegans]
Hydantoinase B/oxoprolinase domain-containing protein [Caenorhabditis elegans]
gi|1972266343|ref|NP_001379804.1|

Protein
Mus musculus metastasis associated lung adenocarcinoma transcript 1 (non-coding ...
Mus musculus metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) (Malat1), long non-coding RNA
gi|1108847852|ref|NR_002847.3|

Nucleotide

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