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Select item 73696541.

Low UGP2 Expression Is Associated with Tumour Progression and Predicts Poor Prognosis in Hepatocellular Carcinoma

Qiuyue Hu, Shen Shen, Jianhao Li, Liwen Liu, Xin Liu, Yingying Zhang, Yongjian Zhou, Weiwei Zhu, Yan Yu, Guangying Cui

Dis Markers. 2020; 2020: 3231273. Published online 2020 Jul 11. doi: 10.1155/2020/3231273

PMCID:: PMC7369654

Abstract Article PDF–3.3M

Select item 71393862.

Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium

Christelle Durrant, Jana I. Fuehring, Alexandra Willemetz, Dominique Chrétien, Giusy Sala, Riccardo Ghidoni, Abram Katz, Agnès Rötig, Monica Thelestam, Myriam Ermonval, Stuart E. H. Moore

Int J Mol Sci. 2020 Mar; 21(6): 2028. Published online 2020 Mar 16. doi: 10.3390/ijms21062028

PMCID:: PMC7139386

Abstract Article PDF–3.6M

Select item 83467923.

UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth

Andrew L. Wolfe, Qingwen Zhou, Eneda Toska, Jacqueline Galeas, Angel A. Ku, Richard P. Koche, Sourav Bandyopadhyay, Maurizio Scaltriti, Carlito B. Lebrilla, Frank McCormick, Sung Eun Kim

Proc Natl Acad Sci U S A. 2021 Aug 3; 118(31): e2103592118. Published online 2021 Jul 30. doi: 10.1073/pnas.2103592118

PMCID:: PMC8346792

Abstract Article PDF–1.1M

Select item 57741104.

Expression of UGP2 and CFL1 expression levels in benign and malignant pancreatic lesions and their clinicopathological significance

Lingxiang Wang, Li Xiong, Zhengchun Wu, Xiongying Miao, Ziru Liu, Daiqiang Li, Qiong Zou, Zhulin Yang

World J Surg Oncol. 2018; 16: 11. Published online 2018 Jan 18. doi: 10.1186/s12957-018-1316-7

PMCID:: PMC5774110

Abstract Article PDF–884K

Select item 70352415.

Loss of UGP2 in brain leads to a severe epileptic encephalopathy, emphasizing that bi-allelic isoform-specific start-loss mutations of essential genes can cause genetic diseases

Elena Perenthaler, Anita Nikoncuk, Soheil Yousefi, Woutje M. Berdowski, Maysoon Alsagob, Ivan Capo, Herma C. van der Linde, Paul van den Berg, Edwin H. Jacobs, Darija Putar, Mehrnaz Ghazvini, Eleonora Aronica, Wilfred F. J. van IJcken, Walter G. de Valk, Evita Medici-van den Herik, Marjon van Slegtenhorst, Lauren Brick, Mariya Kozenko, Jennefer N. Kohler, Jonathan A. Bernstein, Kristin G. Monaghan, Amber Begtrup, Rebecca Torene, Amna Al Futaisi, Fathiya Al Murshedi, Renjith Mani, Faisal Al Azri, Erik-Jan Kamsteeg, Majid Mojarrad, Atieh Eslahi, Zaynab Khazaei, Fateme Massinaei Darmiyan, Mohammad Doosti, Ehsan Ghayoor Karimiani, Jana Vandrovcova, Faisal Zafar, Nuzhat Rana, Krishna K. Kandaswamy, Jozef Hertecant, Peter Bauer, Mohammed A. AlMuhaizea, Mustafa A. Salih, Mazhor Aldosary, Rawan Almass, Laila Al-Quait, Wafa Qubbaj, Serdar Coskun, Khaled O. Alahmadi, Muddathir H. A. Hamad, Salem Alwadaee, Khalid Awartani, Anas M. Dababo, Futwan Almohanna, Dilek Colak, Mohammadreza Dehghani, Mohammad Yahya Vahidi Mehrjardi, Murat Gunel, A. Gulhan Ercan-Sencicek, Gouri Rao Passi, Huma Arshad Cheema, Stephanie Efthymiou, Henry Houlden, Aida M. Bertoli-Avella, Alice S. Brooks, Kyle Retterer, Reza Maroofian, Namik Kaya, Tjakko J. van Ham, Tahsin Stefan Barakat

Acta Neuropathol. 2020; 139(3): 415–442. Published online 2019 Dec 9. doi: 10.1007/s00401-019-02109-6

PMCID:: PMC7035241

Abstract Article PDF–17M

Select item 28373736.

Hypoxia Promotes Glycogen Accumulation through Hypoxia Inducible Factor (HIF)-Mediated Induction of Glycogen Synthase 1

Nuria Pescador, Diego Villar, Daniel Cifuentes, Mar Garcia-Rocha, Amaya Ortiz-Barahona, Silvia Vazquez, Angel Ordoñez, Yolanda Cuevas, David Saez-Morales, Maria Laura Garcia-Bermejo, Manuel O. Landazuri, Joan Guinovart, Luis del Peso

PLoS One. 2010; 5(3): e9644. Published online 2010 Mar 12. doi: 10.1371/journal.pone.0009644

PMCID:: PMC2837373

Abstract Article PDF–887K

Select item 85640147.

Mitochondrial Fission Factor Is a Novel Interacting Protein of the Critical B Cell Survival Regulator TRAF3 in B Lymphocytes

Yingying Liu, Samantha Gokhale, Jaeyong Jung, Sining Zhu, Chang Luo, Debanjan Saha, Jessie Yanxiang Guo, Huaye Zhang, Saw Kyin, Wei-Xing Zong, Eileen White, Ping Xie

Front Immunol. 2021; 12: 670338. Published online 2021 Oct 20. doi: 10.3389/fimmu.2021.670338

PMCID:: PMC8564014

Abstract Article PDF–18M

Select item 41555088.

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles

Jacqueline I Goldstein, L Fredrik Jarskog, Chris Hilliard, Ana Alfirevic, Laramie Duncan, Denis Fourches, Hailiang Huang, Monkol Lek, Benjamin M Neale, Stephan Ripke, Kevin Shianna, Jin P Szatkiewicz, Alexander Tropsha, Edwin JCG van den Oord, Ingolf Cascorbi, Michael Dettling, Ephraim Gazit, Donald C Goff, Arthur L Holden, Deanna L Kelly, Anil K Malhotra, Jimmi Nielsen, Munir Pirmohamed, Dan Rujescu, Thomas Werge, Deborah L Levy, Richard C Josiassen, James L Kennedy, Jeffrey A Lieberman, Mark J Daly, Patrick F Sullivan

Nat Commun. Author manuscript; available in PMC 2015 Mar 4.

Published in final edited form as: Nat Commun. 2014; 5: 4757. Published online 2014 Sep 4. doi: 10.1038/ncomms5757

PMCID:: PMC4155508

Abstract Article PDF–1.8M

Select item 41106369.

Protein interaction discovery using parallel analysis of translated ORFs (PLATO)

Jian Zhu, H. Benjamin Larman, Geng Gao, Romel Somwar, Zijuan Zhang, Uri Laserson, Alberto Ciccia, Natalya Pavlova, George Church, Wei Zhang, Santosh Kesari, Stephen J. Elledge

Nat Biotechnol. Author manuscript; available in PMC 2014 Jul 25.

Published in final edited form as: Nat Biotechnol. 2013 Apr; 31(4): 331–334. Published online 2013 Mar 17. doi: 10.1038/nbt.2539

PMCID:: PMC4110636

Abstract Article PDF–585K

Select item 510887210.

A cascading activity-based probe sequentially targets E1–E2–E3 ubiquitin enzymes

Monique P.C. Mulder, Katharina Witting, Ilana Berlin, Jonathan N. Pruneda, Kuen-Phon Wu, Jer-Gung Chang, Remco Merkx, Johanna Bialas, Marcus Groettrup, Alfred C.O. Vertegaal, Brenda A. Schulman, David Komander, Jacques Neefjes, Farid El Oualid, Huib Ovaa

Nat Chem Biol. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: Nat Chem Biol. 2016 Jul; 12(7): 523–530. Published online 2016 May 16. doi: 10.1038/nchembio.2084

PMCID:: PMC5108872

Abstract Article PDF–2.4M

Select item 1002268611.

Myosin-X recruits lamellipodin to filopodia tips

Ana Popović, Mitro Miihkinen, Sujan Ghimire, Rafael Saup, Max L. B. Grönloh, Neil J. Ball, Benjamin T. Goult, Johanna Ivaska, Guillaume Jacquemet

J Cell Sci. 2023 Mar 1; 136(5): jcs260574. Published online 2023 Mar 2. doi: 10.1242/jcs.260574

PMCID:: PMC10022686

Abstract Article

Select item 901471112.

Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

Fabian Hosp, Hannes Vossfeldt, Matthias Heinig, Djordje Vasiljevic, Anup Arumughan, Emanuel Wyler, Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, Markus Landthaler, Norbert Hubner, Erich E. Wanker, Lars Lannfelt, Martin Ingelsson, Maciej Lalowski, Aaron Voigt, Matthias Selbach

Cell Rep. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Cell Rep. 2015 May 19; 11(7): 1134–1146. Published online 2015 May 7. doi: 10.1016/j.celrep.2015.04.030

PMCID:: PMC9014711

Abstract Article PDF–2.2M

Select item 910272613.

VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway

Zhangya Pu, Dan G. Duda, Yuanyuan Zhu, Siya Pei, Xiaofang Wang, Yan Huang, Panpan Yi, Zebing Huang, Fang Peng, Xingwang Hu, Xuegong Fan

J Transl Med. 2022; 20: 212. Published online 2022 May 13. doi: 10.1186/s12967-022-03416-5

PMCID:: PMC9102726

Abstract Article PDF–15M

Select item 910630314.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 361021415.

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome

Gaëlle Blandin, Sylvie Marchand, Karine Charton, Nathalie Danièle, Evelyne Gicquel, Jean-Baptiste Boucheteil, Azéddine Bentaib, Laetitia Barrault, Daniel Stockholm, Marc Bartoli, Isabelle Richard

Skelet Muscle. 2013; 3: 3. Published online 2013 Feb 15. doi: 10.1186/2044-5040-3-3

PMCID:: PMC3610214

Abstract Article PDF–1.7M

Select item 435840316.

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt

Jernej Murn, Kathi Zarnack, Yawei J. Yang, Omer Durak, Elisabeth A. Murphy, Sihem Cheloufi, Dilenny M. Gonzalez, Marianna Teplova, Tomaž Curk, Johannes Zuber, Dinshaw J. Patel, Jernej Ule, Nicholas M. Luscombe, Li-Huei Tsai, Christopher A. Walsh, Yang Shi

Genes Dev. 2015 Mar 1; 29(5): 501–512. doi: 10.1101/gad.258483.115

PMCID:: PMC4358403

Abstract Article PDF–1.4M

Select item 607772217.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 856647318.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 458732219.

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage

Romain Drissi, Marie-Line Dubois, Mélanie Douziech, François-Michel Boisvert

Mol Cell Proteomics. 2015 Jul; 14(7): 2002–2013. Published online 2015 May 11. doi: 10.1074/mcp.M115.048991

PMCID:: PMC4587322

Abstract Article PDF–3.0M

Select item 1110948320.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

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