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Select item 95699481.

Homozygous CRISPR/Cas9 Knockout Generated a Novel Functionally Active Exon 1 Skipping XPA Variant in Melanoma Cells

Veronika Banicka, Marie Christine Martens, Rüdiger Panzer, David Schrama, Steffen Emmert, Lars Boeckmann, Alexander Thiem

Int J Mol Sci. 2022 Oct; 23(19): 11649. Published online 2022 Oct 1. doi: 10.3390/ijms231911649

PMCID:: PMC9569948

Abstract Article PDF–3.8M

Select item 90961952.

XPA Enhances Temozolomide Resistance of Glioblastoma Cells by Promoting Nucleotide Excision Repair

Weimin Dai, An Wu, Yunping Li, Guofeng Yu, Xinjiang Yan

Cell Transplant. 2022 Jan-Dec; 31: 09636897221092778. Published online 2022 May 10. doi: 10.1177/09636897221092778

PMCID:: PMC9096195

Abstract Article PDF–2.3M

Select item 88780083.

Nucleotide Excision Repair Pathway Activity Is Inhibited by Airborne Particulate Matter (PM₁₀) through XPA Deregulation in Lung Epithelial Cells

Ericka Marel Quezada-Maldonado, Yolanda I. Chirino, María Eugenia Gonsebatt, Rocío Morales-Bárcenas, Yesennia Sánchez-Pérez, Claudia M. García-Cuellar

Int J Mol Sci. 2022 Feb; 23(4): 2224. Published online 2022 Feb 17. doi: 10.3390/ijms23042224

PMCID:: PMC8878008

Abstract Article PDF–2.2M

Select item 71397264.

XPA: DNA Repair Protein of Significant Clinical Importance

Lucia Borszéková Pulzová, Thomas A. Ward, Miroslav Chovanec

Int J Mol Sci. 2020 Mar; 21(6): 2182. Published online 2020 Mar 22. doi: 10.3390/ijms21062182

PMCID:: PMC7139726

Abstract Article PDF–1.1M

Select item 69455135.

Increased levels of XPA might be the basis of cisplatin resistance in germ cell tumours

Zuzana Cierna, Vera Miskovska, Jan Roska, Dana Jurkovicova, Lucia Borszekova Pulzova, Zuzana Sestakova, Lenka Hurbanova, Katarina Machalekova, Michal Chovanec, Katarina Rejlekova, Daniela Svetlovska, Katarina Kalavska, Karol Kajo, Pavel Babal, Jozef Mardiak, Thomas A. Ward, Michal Mego, Miroslav Chovanec

BMC Cancer. 2020; 20: 17. Published online 2020 Jan 6. doi: 10.1186/s12885-019-6496-1

PMCID:: PMC6945513

Abstract Article PDF–1.0M

Select item 67220206.

Alcohol effects on colon epithelium are time dependent

Faraz Bishehsari, Lijuan Zhang, Robin M. Voigt, Natalie Maltby, Bita Semsarieh, Eyas Zorub, Maliha Shaikh, Sherry Wilber, Andrew R Armstrong, Seyed Sina Mirbagheri, Nailliw Z. Preite, Peter Song, Alessia Stornetta, Silvia Balbo, Christopher B. Forsyth, Ali Keshavarzian

Alcohol Clin Exp Res. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Alcohol Clin Exp Res. 2019 Sep; 43(9): 1898–1908. Published online 2019 Jul 22. doi: 10.1111/acer.14141

PMCID:: PMC6722020

Abstract Article PDF–1.2M

Select item 63174617.

The redefined DNA-binding domain of human xeroderma pigmentosum complementation group A: production, crystallization and structure solution

Fu-Ming Lian, Xiangwei Yang, Wancai Yang, Yong-Liang Jiang, Chengmin Qian

Acta Crystallogr F Struct Biol Commun. 2019 Jan 1; 75(Pt 1): 62–66. Published online 2019 Jan 1. doi: 10.1107/S2053230X18016990

PMCID:: PMC6317461

Abstract Article PDF–618K

Select item 62758958.

A functional analysis of G23A polymorphism and the alternative splicing in the expression of the XPA gene

Dorota Butkiewicz, Małgorzata Krześniak, Rasa Vaitiekunaite, Bożena Sikora, Elise D. Bowman, Curtis C. Harris, Marek Rusin

Cell Mol Biol Lett. 2010 Dec; 15(4): 611–629. Published online 2010 Sep 17. doi: 10.2478/s11658-010-0032-2

PMCID:: PMC6275895

Summary PDF–1.1M

Select item 60396759.

Association of XPA polymorphism with breast cancer risk: A meta-analysis

Yunhong Zhang, Qiang Guo, Xunqiang Yin, Xiaoxiao Zhu, Lin Zhao, Zhen Zhang, Ran Wei, Bin Wang, Xia Li

Medicine (Baltimore) 2018 Jun; 97(26): e11276. Published online 2018 Jun 29. doi: 10.1097/MD.0000000000011276

PMCID:: PMC6039675

Abstract Article PDF–1.1M

Select item 573145210.

Transcriptional consequences of XPA disruption in human cell lines

Mandira Manandhar, Megan G. Lowery, Karen S. Boulware, Kevin H. Lin, Yue Lu, Richard D. Wood

DNA Repair (Amst) Author manuscript; available in PMC 2017 Dec 15.

Published in final edited form as: DNA Repair (Amst). 2017 Sep; 57: 76–90. Published online 2017 Jun 29. doi: 10.1016/j.dnarep.2017.06.028

PMCID:: PMC5731452

Abstract Article PDF–1.0M

Select item 571807911.

Genetic investigation of XPA gene: high frequency of the c.682C>T mutation in Moroccan XP patients with moderate clinical profile

Zineb Kindil, Mohamed Amine Senhaji, Amina Bakhchane, Hicham Charoute, Soumia Chihab, Sellama Nadifi, Abdelhamid Barakat

BMC Res Notes. 2017; 10: 704. Published online 2017 Dec 6. doi: 10.1186/s13104-017-3042-6

PMCID:: PMC5718079

Abstract Article PDF–1.2M

Select item 564187312.

Analysis of DNA binding by human factor xeroderma pigmentosum complementation group A (XPA) provides insight into its interactions with nucleotide excision repair substrates

Norie Sugitani, Markus W. Voehler, Michelle S. Roh, Agnieszka M. Topolska-Woś, Walter J. Chazin

J Biol Chem. 2017 Oct 13; 292(41): 16847–16857. Published online 2017 Aug 31. doi: 10.1074/jbc.M117.800078

PMCID:: PMC5641873

Abstract Article PDF–1.4M

Select item 532749913.

Metal binding mediated conformational change of XPA protein: a potential cytotoxic mechanism of nickel in the nucleotide excision repair

Jianping Hu, Ziheng Hu, Yan Zhang, Xiaojun Gou, Ying Mu, Lirong Wang, Xiang-Qun Xie

J Mol Model. Author manuscript; available in PMC 2017 Jul 1.

Published in final edited form as: J Mol Model. 2016 Jul; 22(7): 156. Published online 2016 Jun 16. doi: 10.1007/s00894-016-3017-x

PMCID:: PMC5327499

Abstract Article PDF–1.8M

Select item 502126114.

A Functional Polymorphism (rs10817938) in the XPA Promoter Region Is Associated with Poor Prognosis of Oral Squamous Cell Carcinoma in a Chinese Han Population

Chunhai Gao, Jinzhu Wang, Chong Li, Wei Zhang, Guoxia Liu

PLoS One. 2016; 11(9): e0160801. Published online 2016 Sep 13. doi: 10.1371/journal.pone.0160801

PMCID:: PMC5021261

Abstract Article PDF–1.9M

Select item 495858515.

XPA: A key scaffold for human nucleotide excision repair

Norie Sugitani, Robert M. Sivley, Kelly E. Perry, John A. Capra, Walter J. Chazin

DNA Repair (Amst) Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: DNA Repair (Amst). 2016 Aug; 44: 123–135. Published online 2016 May 20. doi: 10.1016/j.dnarep.2016.05.018

PMCID:: PMC4958585

Abstract Article PDF–2.7M

Select item 469507316.

High expression of XPA confers poor prognosis for nasopharyngeal carcinoma patients treated with platinum-based chemoradiotherapy

Xiang Fu, Jiali Hu, Hong-yu Han, Yi-jun Hua, Ling Zhou, Wen-di Shuai, Wu-ying Du, Chun-mei Kuang, Shuai Chen, Wenlin Huang, Ran-yi Liu

Oncotarget. 2015 Sep 29; 6(29): 28478–28490. Published online 2015 Jun 10. doi: 10.18632/oncotarget.4424

PMCID:: PMC4695073

Abstract Article PDF–6.4M

Select item 464173417.

Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome

Akira Sassa, Nagisa Kamoshita, Yuki Kanemaru, Masamitsu Honma, Manabu Yasui

PLoS One. 2015; 10(11): e0142218. Published online 2015 Nov 11. doi: 10.1371/journal.pone.0142218

PMCID:: PMC4641734

Abstract Article PDF–719K

Select item 442511918.

Xeroderma Pigmentosum: Low Prevalence of Germline XPA Mutations in a Brazilian XP Population

Karina Miranda Santiago, Amanda França de Nóbrega, Rafael Malagoli Rocha, Silvia Regina Rogatto, Maria Isabel Achatz

Int J Mol Sci. 2015 Apr; 16(4): 8988–8996. Published online 2015 Apr 22. doi: 10.3390/ijms16048988

PMCID:: PMC4425119

Abstract Article PDF–3.3M

Select item 426692319.

A new structural insight into XPA–DNA interactions

Benjamin Hilton, Nick Shkriabai, Phillip R. Musich, Mamuka Kvaratskhelia, Steven Shell, Yue Zou

Biosci Rep. 2014; 34(6): e00162. Prepublished online 2014 Nov 7. Published online 2014 Dec 12. doi: 10.1042/BSR20140158

PMCID:: PMC4266923

Abstract Article PDF–752K

Select item 413295620.

Redefining the DNA-Binding Domain of Human XPA

Norie Sugitani, Steven M. Shell, Sarah E. Soss, Walter J. Chazin

J Am Chem Soc. 2014 Aug 6; 136(31): 10830–10833. Published online 2014 Jul 21. doi: 10.1021/ja503020f

PMCID:: PMC4132956

Abstract Article PDF–1.2M

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PMC Links for Gene (Select 7507) (121)
PMC
Homo sapiens tudor and KH domain containing (TDRKH), transcript variant 3, mRNA
Homo sapiens tudor and KH domain containing (TDRKH), transcript variant 3, mRNA
gi|1675028554|ref|NM_006862.4|

Nucleotide
hemogen isoform X1 [Homo sapiens]
hemogen isoform X1 [Homo sapiens]
gi|2462625272|ref|XP_054219212.1|

Protein
Homo sapiens cDNA FLJ10533 fis, clone NT2RP2001056
Homo sapiens cDNA FLJ10533 fis, clone NT2RP2001056
gi|7022625|dbj|AK001395.1|

Nucleotide

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