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Select item 105027861.

ZIC1 Dictates Osteogenesis Versus Adipogenesis in Human Mesenchymal Progenitor Cells Via a Hedgehog Dependent Mechanism

Neelima Thottappillil, Mario A Gomez-Salazar, Mingxin Xu, Qizhi Qin, Xin Xing, Jiajia Xu, Kristen Broderick, Ji-Hye Yea, Mary Archer, Ginny Ching-Yun Hsu, Bruno Péault, Aaron W James

Stem Cells. 2023 Sep; 41(9): 862–876. Published online 2023 Jun 15. doi: 10.1093/stmcls/sxad047

PMCID:: PMC10502786

Abstract Article PDF–36M

Select item 89559932.

Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis

Harish K. Datta, Marianne K. Kringen, Stephen P. Tuck, Georgia Salpingidou, Ole K. Olstad, Kaare M. Gautvik, Simon J. Cockell, Vigdis T. Gautvik, Michael Prediger, Jun Jie Wu, Mark A. Birch, Sjur Reppe

Int J Mol Sci. 2022 Mar; 23(6): 2957. Published online 2022 Mar 9. doi: 10.3390/ijms23062957

PMCID:: PMC8955993

Abstract Article PDF–24M

Select item 64889173.

A single factor induces neuronal differentiation to suppress glioma cell growth

Ji‐Qiang Fu, Zhen Chen, Yong‐Jia Hu, Zhao‐Huan Fan, Zhen‐Xing Guo, Jin‐Ye Liang, Bo‐Mi Ryu, Jian‐Lin Ren, Xiu‐Juan Shi, Jiao Li, Song Jia, Juan Wang, Xiao‐Si Ke, Xin Ma, Xiao Tan, Ting Zhang, Xian‐Zhen Chen, Chen Zhang

CNS Neurosci Ther. 2019 Apr; 25(4): 486–495. Published online 2018 Sep 27. doi: 10.1111/cns.13066

PMCID:: PMC6488917

Abstract Article PDF–1.5M

Select item 45147714.

Zic1 Promoter Hypermethylation in Plasma DNA Is a Potential Biomarker for Gastric Cancer and Intraepithelial Neoplasia

Xueqin Chen, Zhenghua Lin, Meng Xue, Jianmin Si, Shujie Chen

PLoS One. 2015; 10(7): e0133906. Published online 2015 Jul 24. doi: 10.1371/journal.pone.0133906

PMCID:: PMC4514771

Abstract Article PDF–844K

Select item 38573425.

Comprehensive methylome analysis of ovarian tumors reveals hedgehog signaling pathway regulators as prognostic DNA methylation biomarkers

Rui-Lan Huang, Fei Gu, Nameer B. Kirma, Jianhua Ruan, Chun-Liang Chen, Hui-Chen Wang, Yu-Ping Liao, Cheng-Chang Chang, Mu-Hsien Yu, Jay M. Pilrose, Ian M. Thompson, Hsuan-Cheng Huang, Tim Hui-Ming Huang, Hung-Cheng Lai, Kenneth P. Nephew

Epigenetics. 2013 Jun 1; 8(6): 624–634. Published online 2013 May 10. doi: 10.4161/epi.24816

PMCID:: PMC3857342

Abstract Article PDF–2.1M

Select item 34114116.

ZIC1 modulates cell-cycle distributions and cell migration through regulation of sonic hedgehog, PI₃K and MAPK signaling pathways in gastric cancer

Jing Zhong, Shujie Chen, Meng Xue, Qin Du, Jianting Cai, Hongchuan Jin, Jianmin Si, Liangjing Wang

BMC Cancer. 2012; 12: 290. Published online 2012 Jul 16. doi: 10.1186/1471-2407-12-290

PMCID:: PMC3411411

Abstract Article PDF–1.7M

Select item 30396537.

ZIC1 Is Downregulated through Promoter Hypermethylation, and Functions as a Tumor Suppressor Gene in Colorectal Cancer

Lihong Gan, Shujie Chen, Jing Zhong, Xian Wang, Emily K. Y. Lam, Xin Liu, Jianbin Zhang, Tianhua Zhou, Jun Yu, Jianmin Si, Liangjing Wang, Hongchuan Jin

PLoS One. 2011; 6(2): e16916. Published online 2011 Feb 15. doi: 10.1371/journal.pone.0016916

PMCID:: PMC3039653

Abstract Article PDF–1.8M

Select item 24419888.

Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif

Amit Arora, Mariola Dutkiewicz, Vinod Scaria, Manoj Hariharan, Souvik Maiti, Jens Kurreck

RNA. 2008 Jul; 14(7): 1290–1296. doi: 10.1261/rna.1001708

PMCID:: PMC2441988

Abstract Article PDF–368K

Select item 100528099.

Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy

Franziska Hopfner, Anja K. Tietz, Viktoria C. Ruf, Owen A. Ross, Shunsuke Koga, Dennis Dickson, Adriano Aguzzi, Johannes Attems, Thomas Beach, Allison Beller, William P. Cheshire, Vivianna van Deerlin, Paula Desplats, Günther Deuschl, Charles Duyckaerts, David Ellinghaus, Valentin Evsyukov, Margaret Ellen Flanagan, Andre Franke, Matthew P. Frosch, Marla Gearing, Ellen Gelpi, Jay A. van Gerpen, Bernardino Ghetti, Jonathan D. Glass, Lea T. Grinberg, Glenda Halliday, Ingo Helbig, Matthias Höllerhage, Inge Huitinga, David John Irwin, Dirk C. Keene, Gabor G. Kovacs, Edward B. Lee, Johannes Levin, Maria J. Martí, Ian Mackenzie, Ian McKeith, Catriona Mclean, Brit Mollenhauer, Manuela Neumann, Kathy L. Newell, Alex Pantelyat, Manuela Pendziwiat, Annette Peters, Laura Molina Porcel, Alberto Rabano, Radoslav Matěj, Alex Rajput, Ali Rajput, Regina Reimann, William K. Scott, William Seeley, Sashika Selvackadunco, Tanya Simuni, Christine Stadelmann, Per Svenningsson, Alan Thomas, Claudia Trenkwalder, Claire Troakes, John Q. Trojanowski, Ryan J. Uitti, Charles L. White, Zbigniew K. Wszolek, Tao Xie, Teresa Ximelis, Yebenes Justo, Alzheimer’s Disease Genetics Consortium, Ulrich Müller, Gerard D. Schellenberg, Jochen Herms, Gregor Kuhlenbäumer, Günter Höglinger

Mov Disord. Author manuscript; available in PMC 2023 Oct 1.

Published in final edited form as: Mov Disord. 2022 Oct; 37(10): 2110–2121. Published online 2022 Aug 23. doi: 10.1002/mds.29164

PMCID:: PMC10052809

Abstract Article PDF–1.2M

Select item 914110010.

Jürgen Serth, Inga Peters, Bastian Hill, Tatjana Hübscher, Jörg Hennenlotter, Michael Klintschar, Markus Antonius Kuczyk

Int J Mol Sci. 2022 May; 23(10): 5327. Published online 2022 May 10. doi: 10.3390/ijms23105327

PMCID:: PMC9141100

Abstract Article PDF–11M

Select item 606545211.

ZIC1 acts a tumor suppressor in breast cancer by targeting survivin

Wei Han, Fang Cao, Xiao-Jiao Gao, Hua-Bing Wang, Fang Chen, Si-Jian Cai, Cong Zhang, Yong-Wei Hu, Jun Ma, Xing Gu, Hou-Zhong Ding

Int J Oncol. 2018 Sep; 53(3): 937–948. Published online 2018 Jun 21. doi: 10.3892/ijo.2018.4450

PMCID:: PMC6065452

Abstract Article PDF–1.2M

Select item 326695012.

ZIC1 Overexpression Is Oncogenic in Liposarcoma

Elliott Brill, Ryan Gobble, Christina Angeles, Mariana Lagos-Quintana, Aimee Crago, Bernadette Laxa, Penelope DeCarolis, Lei Zhang, Cristina Antonescu, Nicholas D. Socci, Barry S. Taylor, Chris Sander, Andrew Koff, Samuel Singer

Cancer Res. Author manuscript; available in PMC 2012 Jan 26.

Published in final edited form as: Cancer Res. 2010 Sep 1; 70(17): 6891–6901. Published online 2010 Aug 16. doi: 10.1158/0008-5472.CAN-10-0745

PMCID:: PMC3266950

Abstract Article PDF–2.9M

Select item 841327413.

Transcriptional expression of ZICs as an independent indicator of survival in gliomas

Zhaocheng Han, Jingnan Jia, Yangting Lv, Rongyanqi Wang, Kegang Cao

Sci Rep. 2021; 11: 17532. Published online 2021 Sep 2. doi: 10.1038/s41598-021-93877-3

PMCID:: PMC8413274

Abstract Article PDF–3.7M

Select item 456489514.

Gain-of-Function Mutations in ZIC1 Are Associated with Coronal Craniosynostosis and Learning Disability

Stephen R.F. Twigg, Jennifer Forecki, Jacqueline A.C. Goos, Ivy C.A. Richardson, A. Jeannette M. Hoogeboom, Ans M.W. van den Ouweland, Sigrid M.A. Swagemakers, Maarten H. Lequin, Daniel Van Antwerp, Simon J. McGowan, Isabelle Westbury, Kerry A. Miller, Steven A. Wall, WGS500 Consortium, Peter J. van der Spek, Irene M.J. Mathijssen, Erwin Pauws, Christa S. Merzdorf, Andrew O.M. Wilkie

Am J Hum Genet. 2015 Sep 3; 97(3): 378–388. Published online 2015 Sep 3. doi: 10.1016/j.ajhg.2015.07.007

PMCID:: PMC4564895

Abstract Article PDF–1.7M

Select item 283882315.

Expression of ZIC family genes in meningiomas and other brain tumors

Jun Aruga, Yayoi Nozaki, Minoru Hatayama, Yuri S Odaka, Naoki Yokota

BMC Cancer. 2010; 10: 79. Published online 2010 Mar 3. doi: 10.1186/1471-2407-10-79

PMCID:: PMC2838823

Abstract Article PDF–2.8M

Select item 375170016.

The role of Zic transcription factors in regulating hindbrain retinoic acid signaling

Danna L Drummond, Caroline S Cheng, Lyndsay G Selland, Jennifer C Hocking, Lisa B Prichard, Andrew J Waskiewicz

BMC Dev Biol. 2013; 13: 31. Published online 2013 Aug 12. doi: 10.1186/1471-213X-13-31

PMCID:: PMC3751700

Abstract Article PDF–7.0M

Select item 433481417.

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis

Sergio E. Baranzini, Joanne Wang, Rachel A. Gibson, Nicholas Galwey, Yvonne Naegelin, Frederik Barkhof, Ernst-Wilhelm Radue, Raija L.P. Lindberg, Bernard M.G. Uitdehaag, Michael R. Johnson, Aspasia Angelakopoulou, Leslie Hall, Jill C. Richardson, Rab K. Prinjha, Achim Gass, Jeroen J.G. Geurts, Jolijn Kragt, Madeleine Sombekke, Hugo Vrenken, Pamela Qualley, Robin R. Lincoln, Refujia Gomez, Stacy J. Caillier, Michaela F. George, Hourieh Mousavi, Rosa Guerrero, Darin T. Okuda, Bruce A. C. Cree, Ari J. Green, Emmanuelle Waubant, Douglas S. Goodin, Daniel Pelletier, Paul M. Matthews, Stephen L. Hauser, Ludwig Kappos, Chris H. Polman, Jorge R. Oksenberg

Hum Mol Genet. 2009 Feb 15; 18(4): 767–778. Published online 2008 Nov 14. doi: 10.1093/hmg/ddn388

PMCID:: PMC4334814

Abstract Article PDF–274K

Select item 1626718.

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags

Emmanuel Dias Neto, Ricardo Garcia Correa, Sergio Verjovski-Almeida, Marcelo R. S. Briones, Maria Aparecida Nagai, Wilson da Silva, Jr., Marco Antonio Zago, Silvana Bordin, Fernando Ferreira Costa, Gustavo Henrique Goldman, Alex F. Carvalho, Adriana Matsukuma, Gilson S. Baia, David H. Simpson, Adriana Brunstein, Paulo S. L. de Oliveira, Philipp Bucher, C. Victor Jongeneel, Michael J. O'Hare, Fernando Soares, Ricardo R. Brentani, Luis F. L. Reis, Sandro J. de Souza, Andrew J. G. Simpson

Proc Natl Acad Sci U S A. 2000 Mar 28; 97(7): 3491–3496. doi: 10.1073/pnas.97.7.3491

PMCID:: PMC16267

Abstract Article PDF–111K

Select item 800904819.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 13914620.

Large-Scale Concatenation cDNA Sequencing

Wei Yu, Björn Andersson, Kim C. Worley, Donna M. Muzny, Yan Ding, Wen Liu, Jennifer Y. Ricafrente, Meredith A. Wentland, Greg Lennon, Richard A. Gibbs

Genome Res. 1997 Apr; 7(4): 353–358. doi: 10.1101/gr.7.4.353

PMCID:: PMC139146

Abstract Article PDF–62K

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