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Select item 78231871.

Correlation of zinc finger protein 2, a prognostic biomarker, with immune infiltrates in liver cancer

Lei Sun, Yaru Lin, Guichun Wang, Lin Zhang, Liangchang Hu, Zhong Lu

Biosci Rep. 2021 Jan 29; 41(1): BSR20203115. Published online 2021 Jan 22. doi: 10.1042/BSR20203115

PMCID:: PMC7823187

Abstract Article PDF–1.4M

Select item 68053382.

Random forest-based modelling to detect biomarkers for prostate cancer progression

Reka Toth, Heiko Schiffmann, Claudia Hube-Magg, Franziska Büscheck, Doris Höflmayer, Sören Weidemann, Patrick Lebok, Christoph Fraune, Sarah Minner, Thorsten Schlomm, Guido Sauter, Christoph Plass, Yassen Assenov, Ronald Simon, Jan Meiners, Clarissa Gerhäuser

Clin Epigenetics. 2019; 11: 148. Published online 2019 Oct 22. doi: 10.1186/s13148-019-0736-8

PMCID:: PMC6805338

Abstract Article PDF–2.6M

Select item 57631573.

In-depth investigations of adolescents and adults with holoprosencephaly identify unique characteristics

Karin Weiss, Paul Kruszka, Maria J Guillen Sacoto, Yonit A Addissie, Donald W Hadley, Casey K Hadsall, Bethany Stokes, Ping Hu, Erich Roessler, Beth Solomon, Edythe Wiggs, Audrey Thurm, Robert B Hufnagel, Wadih M Zein, Jin S Hahn, Elaine Stashinko, Eric Levey, Debbie Baldwin, Nancy J Clegg, Mauricio R Delgado, Maximilian Muenke

Genet Med. 2018 Jan; 20(1): 14–23. Published online 2017 Jun 22. doi: 10.1038/gim.2017.68

PMCID:: PMC5763157

Abstract Article PDF–1004K

Select item 46950584.

Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2

Shingo Inaguma, Hideaki Ito, Miho Riku, Hiroshi Ikeda, Kenji Kasai

Oncotarget. 2015 Sep 29; 6(29): 28257–28268. Published online 2015 Jul 22. doi: 10.18632/oncotarget.4960

PMCID:: PMC4695058

Abstract Article PDF–2.8M

Select item 45821555.

The zinc finger gene ZIC2 has features of an oncogene and its over- expression correlates strongly with the clinical course of epithelial ovarian cancer

Sergio Marchini, Elizabeth Poynor, Richard R Barakat, Luca Clivio, Michela Cinquini, Robert Fruscio, Luca Porcu, Cecilia Bussani, Maurizio D’Incalci, Eugenio Erba, Michela Romano, Giorgio Cattoretti, Dionyssios Katsaros, Andrew Koff, Lucio Luzzatto

Clin Cancer Res. Author manuscript; available in PMC 2015 Sep 25.

Published in final edited form as: Clin Cancer Res. 2012 Aug 15; 18(16): 4313–4324. Published online 2012 Jun 25. doi: 10.1158/1078-0432.CCR-12-0037

PMCID:: PMC4582155

Abstract Article PDF–1.1M

Select item 34091916.

Unique Alterations of an Ultraconserved Non-Coding Element in the 3′UTR of ZIC2 in Holoprosencephaly

Erich Roessler, Ping Hu, Sung-Kook Hong, Kshitij Srivastava, Blake Carrington, Raman Sood, Hanna Petrykowska, Laura Elnitski, Lucilene A. Ribeiro, Antonio Richieri-Costa, Benjamin Feldman, Ward F. Odenwald, Maximilian Muenke

PLoS One. 2012; 7(7): e39026. Published online 2012 Jul 31. doi: 10.1371/journal.pone.0039026

PMCID:: PMC3409191

Abstract Article PDF–363K

Select item 32086267.

Mutations in ZIC2 in human holoprosencephaly: description of a novel ZIC2 specific phenotype and comprehensive analysis of 157 individuals

Benjamin D. Solomon, Felicitas Lacbawan, Sandra Mercier, Nancy J. Clegg, Mauricio R. Delgado, Kenneth Rosenbaum, Christèle Dubourg, Véronique David, Ann Haskins Olney, Lars-Erik Wehner, Ute Hehr, Sherri Bale, Aimee Paulussen, Hubert J. Smeets, Emily Hardisty, Anna Tylki-Szymanska, Ewa Pronicka, Michelle Clemens, Elizabeth Mcpherson, Raoul Cm Hennekam, Jin Hahn, Elaine Stashinko, Eric Levey, Dagmar Wieczorek, Elizabeth Roeder, Chayim Can Schell-Apacik, Carol W. Booth, Ronald L. Thomas, Sue Kenwrick, Amelia Keaton, Joan Z. Balog, Donald Hadley, Nan Zhou, Robert Long, Jorge I. Velez, Daniel E. Pineda-Alvarez, Sylvie Odent, Erich Roessler, Maximilian Muenke

J Med Genet. Author manuscript; available in PMC 2011 Nov 7.

Published in final edited form as: J Med Genet. 2010 Aug; 47(8): 513–524. Published online 2009 Dec 2. doi: 10.1136/jmg.2009.073049

PMCID:: PMC3208626

Abstract Article

Select item 31995168.

Transcription Factor Zic2 Inhibits Wnt/β-Catenin Protein Signaling

Rasoul Pourebrahim, Rob Houtmeyers, Stephen Ghogomu, Sylvie Janssens, Aurore Thelie, Hong Thi Tran, Tobias Langenberg, Kris Vleminckx, Eric Bellefroid, Jean-Jacques Cassiman, Sabine Tejpar

J Biol Chem. 2011 Oct 28; 286(43): 37732–37740. Published online 2011 Sep 9. doi: 10.1074/jbc.M111.242826

PMCID:: PMC3199516

Abstract Article PDF–1.5M

Select item 31219089.

Recurrent Partial Rhombencephalosynapsis and Holoprosencephaly in Siblings with a Mutation of ZIC2

Melissa B. Ramocki, Fernando Scaglia, Pawel Stankiewicz, John W. Belmont, Jeremy Y. Jones, Gary D. Clark

Am J Med Genet A. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Am J Med Genet A. 2011 Jul; 155(7): 1574–1580. Published online 2011 Jun 2. doi: 10.1002/ajmg.a.34029

PMCID:: PMC3121908

Abstract Article PDF–465K

Select item 267458210.

The Full Spectrum of Holoprosencephaly-Associated Mutations within the ZIC2 Gene in Humans Predicts Loss-of-Function as the Predominant Disease Mechanism

Erich Roessler, Felicitas Lacbawan, Christèle Dubourg, Aimee Paulussen, Jos Herbergs, Ute Hehr, Claude Bendavid, Nan Zhou, Maia Ouspenskaia, Sherri Bale, Sylvie Odent, Vèronique David, Maximilian Muenke

Hum Mutat. Author manuscript; available in PMC 2010 Apr 1.

Published in final edited form as: Hum Mutat. 2009 Apr; 30(4): E541–E554. doi: 10.1002/humu.20982

PMCID:: PMC2674582

Abstract Article PDF–478K

Select item 828131311.

ZIC2 upregulates lncRNA SNHG12 expression to promote endometrial cancer cell proliferation and migration by activating the Notch signaling pathway

Pengyu Cai, Gaijuan Li, Mingxiu Wu, Bin Zhang, Hong Bai

Mol Med Rep. 2021 Sep; 24(3): 632. Published online 2021 Jul 5. doi: 10.3892/mmr.2021.12271

PMCID:: PMC8281313

Abstract Article PDF–6.1M

Select item 818499112.

Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin

Zhengshui Xu, Jianbao Zheng, Zilu Chen, Jing Guo, Xiaopeng Li, Xingjie Wang, Chao Qu, Liyue Yuan, Chen Cheng, Xuejun Sun, Junhui Yu

Cell Death Dis. 2021 Jun; 12(6): 584. Published online 2021 Jun 7. doi: 10.1038/s41419-021-03863-w

PMCID:: PMC8184991

Abstract Article PDF–2.8M

Select item 791383013.

De Novo PORCN and ZIC2 Mutations in a Highly Consanguineous Family

Laura Castilla-Vallmanya, Semra Gürsoy, Özlem Giray-Bozkaya, Aina Prat-Planas, Gemma Bullich, Leslie Matalonga, Mónica Centeno-Pla, Raquel Rabionet, Daniel Grinberg, Susanna Balcells, Roser Urreizti

Int J Mol Sci. 2021 Feb; 22(4): 1549. Published online 2021 Feb 4. doi: 10.3390/ijms22041549

PMCID:: PMC7913830

Abstract Article PDF–9.0M

Select item 784844714.

miR-1284 Inhibits the Growth and Invasion of Breast Cancer Cells by Targeting ZIC2

Pengcheng Zhang, Fang Yang, Qin Luo, Daxue Yan, Shengrong Sun

Oncol Res. 2019; 27(2): 253–260. Published online 2019 Feb 5. doi: 10.3727/096504018X15242763477504

PMCID:: PMC7848447

Abstract Article PDF–5.2M

Select item 629779515.

miR-1271-5p inhibits cell proliferation and induces apoptosis in acute myeloid leukemia by targeting ZIC2

Xiaohe Chen, Shouhang Yang, Jue Zeng, Ming Chen

Mol Med Rep. 2019 Jan; 19(1): 508–514. Published online 2018 Nov 21. doi: 10.3892/mmr.2018.9680

PMCID:: PMC6297795

Abstract Article PDF–1.0M

Select item 1036201016.

ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis

Qian Liu, Ting Yang, Yu Zhang, Ze-Dong Hu, Yan-Min Liu, Yi-Ling Luo, Shang-Xin Liu, Hua Zhang, Qian Zhong

Cell Death Dis. 2023 Jul; 14(7): 455. Published online 2023 Jul 21. doi: 10.1038/s41419-023-05983-x

PMCID:: PMC10362010

Abstract Article PDF–6.1M

Select item 831246517.

Downregulation of LINC00665 suppresses the progression of lung adenocarcinoma via regulating miR-181c-5p/ZIC2 axis

Wei Wei, Xiaoliang Zhao, Jiang Liu, Zhenfa Zhang

Aging (Albany NY) 2021 Jul 15; 13(13): 17499–17515. Published online 2021 Jul 7. doi: 10.18632/aging.203240

PMCID:: PMC8312465

Abstract Article PDF–2.6M

Select item 460711818.

ZIC2-dependent OCT4 activation drives self-renewal of human liver cancer stem cells

Pingping Zhu, Yanying Wang, Lei He, Guanling Huang, Ying Du, Geng Zhang, Xinlong Yan, Pengyan Xia, Buqing Ye, Shuo Wang, Lu Hao, Jiayi Wu, Zusen Fan

J Clin Invest. 2015 Oct 1; 125(10): 3795–3808. Published online 2015 Aug 31. doi: 10.1172/JCI81979

PMCID:: PMC4607118

Abstract Article PDF–6.5M

Select item 350155119.

Comparison of mutation findings in ZIC2 between microform and classical holoprosencephaly in a Brazilian cohort

Lucilene A. Ribeiro, Erich Roessler, Ping Hu, Daniel E. Pineda-Alvarez, Nan Zhou, MaryPat Jones, Settara Chandrasekharappa, Antonio Richieri-Costa, Maximilian Muenke

Birth Defects Res A Clin Mol Teratol. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Birth Defects Res A Clin Mol Teratol. 2012 Nov; 94(11): 912–917. Published online 2012 Jul 27. doi: 10.1002/bdra.23047

PMCID:: PMC3501551

Abstract Article PDF–299K

Select item 283882320.

Expression of ZIC family genes in meningiomas and other brain tumors

Jun Aruga, Yayoi Nozaki, Minoru Hatayama, Yuri S Odaka, Naoki Yokota

BMC Cancer. 2010; 10: 79. Published online 2010 Mar 3. doi: 10.1186/1471-2407-10-79

PMCID:: PMC2838823

Abstract Article PDF–2.8M

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