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Select item 53253691.

Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer

Xiao-Feng Wang, Xiao-Wei Zhang, Rui-Xi Hua, Yi-Qun Du, Ming-Zhu Huang, Yong Liu, Yu Fang Cheng, Wei-Jian Guo

Oncotarget. 2016 Sep 27; 7(39): 63352–63361. Published online 2016 Aug 11. doi: 10.18632/oncotarget.11221

PMCID:: PMC5325369

Abstract Article PDF–3.1M

Select item 44631882.

MEL-18 loss mediates estrogen receptor–α downregulation and hormone independence

Jeong-Yeon Lee, Hee-Young Won, Ji-Hye Park, Hye-Yeon Kim, Hee-Joo Choi, Dong-Hui Shin, Ju-Hee Kang, Jong-Kyu Woo, Seung-Hyun Oh, Taekwon Son, Jin-Woo Choi, Sehwan Kim, Hyung-Yong Kim, Kijong Yi, Ki-Seok Jang, Young-Ha Oh, Gu Kong

J Clin Invest. 2015 May 1; 125(5): 1801–1814. Published online 2015 Mar 30. doi: 10.1172/JCI73743

PMCID:: PMC4463188

Abstract Article PDF–4.8M

Select item 30151673.

Polycomb genes expression as a predictor of poor clinical outcome in children with medulloblastoma

Magdalena Zakrzewska, Krzysztof Zakrzewski, Sylwia M. Grešner, Sylwester Piaskowski, Beata Zalewska-Szewczyk, Paweł P. Liberski

Childs Nerv Syst. 2011; 27(1): 79–86. Published online 2010 Aug 18. doi: 10.1007/s00381-010-1260-5

PMCID:: PMC3015167

Abstract Article PDF–359K

Select item 30130884.

Expression of BMI-1 and Mel-18 in breast tissue - a diagnostic marker in patients with breast cancer

Margit LH Riis, Torben Lüders, Anne-Jorunn Nesbakken, Hilde S Vollan, Vessela Kristensen, Ida RK Bukholm

BMC Cancer. 2010; 10: 686. Published online 2010 Dec 16. doi: 10.1186/1471-2407-10-686

PMCID:: PMC3013088

Abstract Article PDF–546K

Select item 29936585.

Expression and clinicopathological significance of Mel-18 and Bmi-1 mRNA in gastric carcinoma

You-Wei Lu, Jin Li, Wei-Jian Guo

J Exp Clin Cancer Res. 2010; 29(1): 143. Published online 2010 Nov 8. doi: 10.1186/1756-9966-29-143

PMCID:: PMC2993658

Abstract Article PDF–386K

Select item 28422376.

BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer

Xiao-Wei Zhang, Ya-Ping Sheng, Qian Li, Wei Qin, You-Wei Lu, Yu-Fan Cheng, Bing-Ya Liu, Feng-Chun Zhang, Jin Li, Goberdhan P Dimri, Wei-Jian Guo

Mol Cancer. 2010; 9: 40. Published online 2010 Feb 21. doi: 10.1186/1476-4598-9-40

PMCID:: PMC2842237

Abstract Article PDF–2.5M

Select item 23866627.

MEL-18 ACTS AS A TUMOR SUPPRESSOR BY REPRESSING BMI-1 EXPRESSION AND DOWN-REGULATING AKT ACTIVITY IN BREAST CANCER CELLS

Wei-Jian Guo, Mu-Sheng Zeng, Ajay Yadav, Li-Bing Song, Bao-Hong Guo, Vimla Band, Goberdhan P. Dimri

Cancer Res. Author manuscript; available in PMC 2008 Jun 1.

Published in final edited form as: Cancer Res. 2007 Jun 1; 67(11): 5083–5089. doi: 10.1158/0008-5472.CAN-06-4368

PMCID:: PMC2386662

Abstract Article PDF–2.2M

Select item 19514878.

Contribution of Polycomb Homologues Bmi-1 and Mel-18 to Medulloblastoma Pathogenesis

Dmitri Wiederschain, Lin Chen, Brett Johnson, Kimberly Bettano, Dowdy Jackson, John Taraszka, Y. Karen Wang, Michael D. Jones, Michael Morrissey, James Deeds, Rebecca Mosher, Paul Fordjour, Christoph Lengauer, John D. Benson

Mol Cell Biol. 2007 Jul; 27(13): 4968–4979. Published online 2007 Apr 23. doi: 10.1128/MCB.02244-06

PMCID:: PMC1951487

Abstract Article PDF–990K

Select item 25624519.

Mel-18 interacts with RanGAP1 and inhibits its sumoylation

Jie Zhang, Kevin D. Sarge

Biochem Biophys Res Commun. Author manuscript; available in PMC 2009 Oct 17.

Published in final edited form as: Biochem Biophys Res Commun. 2008 Oct 17; 375(2): 252–255. Published online 2008 Aug 14. doi: 10.1016/j.bbrc.2008.08.012

PMCID:: PMC2562451

Abstract Article PDF–697K

Select item 178376810.

Mel-18, a Polycomb Group Protein, Regulates Cell Proliferation and Senescence via Transcriptional Repression of Bmi-1 and c-Myc Oncoproteins

Wei-Jian Guo, Sonal Datta, Vimla Band, Goberdhan P. Dimri

Mol Biol Cell. 2007 Feb; 18(2): 536–546. doi: 10.1091/mbc.E06-05-0447

PMCID:: PMC1783768

Abstract Article PDF–1.8M

Select item 227490011.

MEL-18 Interacts with HSF2 and the SUMO E2 UBC9 to Inhibit HSF2 Sumoylation

Jie Zhang, Michael L. Goodson, Yiling Hong, Kevin D. Sarge

J Biol Chem. 2008 Mar 21; 283(12): 7464–7469. doi: 10.1074/jbc.M707122200

PMCID:: PMC2274900

Abstract Article PDF–962K

Select item 340599912.

Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity

Mitsuhiro Endoh, Takaho A. Endo, Tamie Endoh, Kyo-ichi Isono, Jafar Sharif, Osamu Ohara, Tetsuro Toyoda, Takashi Ito, Ragnhild Eskeland, Wendy A. Bickmore, Miguel Vidal, Bradley E. Bernstein, Haruhiko Koseki

PLoS Genet. 2012 Jul; 8(7): e1002774. Published online 2012 Jul 26. doi: 10.1371/journal.pgen.1002774

PMCID:: PMC3405999

Abstract Article PDF–459K

Select item 677182413.

Topology and enzymatic properties of a canonical Polycomb repressive complex 1 isoform

Matteo Colombo, Ombeline Pessey, Marco Marcia

FEBS Lett. 2019 Jul; 593(14): 1837–1848. Published online 2019 May 29. doi: 10.1002/1873-3468.13442

PMCID:: PMC6771824

Abstract Article PDF–1.1M

Select item 912086014.

Functional redundancy among Polycomb complexes in maintaining the pluripotent state of embryonic stem cells

Yaru Zhu, Lixia Dong, Congcong Wang, Kunying Hao, Jingnan Wang, Linchun Zhao, Lijun Xu, Yin Xia, Qing Jiang, Jinzhong Qin

Stem Cell Reports. 2022 May 10; 17(5): 1198–1214. Published online 2022 Mar 31. doi: 10.1016/j.stemcr.2022.02.020

PMCID:: PMC9120860

Abstract Article PDF–8.6M

Select item 400390915.

Structure of the Polycomb Group protein PCGF1 (NSPC1) in complex with BCOR reveals basis for binding selectivity of PCGF homologs

Sarah E. Junco, Renjing Wang, John C. Gaipa, Alexander B. Taylor, Virgil Schirf, Micah D. Gearhart, Vivian J. Bardwell, Borries Demeler, P. John Hart, Chongwoo A. Kim

Structure. Author manuscript; available in PMC 2014 Apr 29.

Published in final edited form as: Structure. 2013 Apr 2; 21(4): 665–671. Published online 2013 Mar 21. doi: 10.1016/j.str.2013.02.013