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Select item 62558271.

Phosphatase of Regenerating Liver-1 (PRL-1) Regulates Actin Dynamics During Immunological Synapse Assembly and T Cell Effector Function

Patricia Castro-Sánchez, Rocío Ramirez-Munoz, Noa B. Martín-Cófreces, Oscar Aguilar-Sopeña, Sergio Alegre-Gomez, Sara Hernández-Pérez, Raquel Reyes, Qi Zeng, Carlos Cabañas, Francisco Sánchez-Madrid, Pedro Roda-Navarro

Front Immunol. 2018; 9: 2655. Published online 2018 Nov 20. doi: 10.3389/fimmu.2018.02655

PMCID:: PMC6255827

Abstract Article PDF–9.3M

Select item 53427352.

Protein tyrosine phosphatase PTP4A1 promotes proliferation and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma via the PI3K/AKT pathway

Long-Zi Liu, Yi-Zhou He, Ping-Ping Dong, Li-Jie Ma, Zhi-Chao Wang, Xin-Yang Liu, Meng Duan, Liu-Xiao Yang, Jie-Yi Shi, Jian Zhou, Jia Fan, Qiang Gao, Xiao-Ying Wang

Oncotarget. 2016 Nov 15; 7(46): 75210–75220. Published online 2016 Sep 19. doi: 10.18632/oncotarget.12116

PMCID:: PMC5342735

Abstract Article PDF–11M

Select item 41165133.

Oncogenic function and prognostic significance of protein tyrosine phosphatase PRL-1 in hepatocellular carcinoma

Shaowen Jin, Kaimei Wang, Kang Xu, Junyao Xu, Jian Sun, Zhonghua Chu, Dechen Lin, Phillip H. Koeffler, Jie Wang, Dong Yin

Oncotarget. 2014 Jun; 5(11): 3685–3696. Published online 2014 May 19. doi: 10.18632/oncotarget.1986

PMCID:: PMC4116513

Abstract Article PDF–2.7M

Select item 27597774.

Enzyme Activity of Phosphatase of Regenerating Liver (PRL-1) Is Controlled by Redox Environment and Its C-terminal Residues

Andria L. Skinner, Anthony A. Vartia, Todd D. Williams, Jennifer S. Laurence

Biochemistry. Author manuscript; available in PMC 2010 May 26.

Published in final edited form as: Biochemistry. 2009 May 26; 48(20): 4262–4272. doi: 10.1021/bi900241k

PMCID:: PMC2759777

Abstract Article PDF–3.0M

Select item 104119435.

Endothelial PTP4A1 mitigates vascular inflammation via USF1/A20 axis-mediated NF-κB inactivation

Min Ji Cho, Dong Gwang Lee, Jeong Woong Lee, Byungtae Hwang, Sung-Jin Yoon, Seon-Jin Lee, Young-Jun Park, Seung-Ho Park, Hee Gu Lee, Yong-Hoon Kim, Chul-Ho Lee, Jangwook Lee, Nam-Kyung Lee, Tae-Su Han, Hyun-Soo Cho, Jeong Hee Moon, Ga Seul Lee, Kwang-Hee Bae, Geum-Sook Hwang, Sang-Hak Lee, Sang J Chung, Sungbo Shim, Jaehyung Cho, Goo Taeg Oh, Young-Guen Kwon, Jong-Gil Park, Jeong-Ki Min

Cardiovasc Res. 2023 May; 119(5): 1265–1278. Published online 2022 Dec 19. doi: 10.1093/cvr/cvac193

PMCID:: PMC10411943

Abstract Article PDF–1.6M

Select item 88551636.

GINS2 regulates the proliferation and apoptosis of colon cancer cells through PTP4A1

Hao Hu, Lina Ye, Zhe Liu

Mol Med Rep. 2022 Apr; 25(4): 117. Published online 2022 Feb 8. doi: 10.3892/mmr.2022.12633

PMCID:: PMC8855163

Abstract Article PDF–5.6M

Select item 62596077.

miR-339-5p Increases Radiosensitivity of Lung Cancer Cells by Targeting Phosphatases of Regenerating Liver-1 (PRL-1)

Jia Wang, Mawei Jiang, Shian Xia

Med Sci Monit. 2018; 24: 8408–8416. Published online 2018 Nov 21. doi: 10.12659/MSM.910808

PMCID:: PMC6259607

Abstract Article PDF–1.6M

Select item 39581268.

Cellular Localization of PRL-1 and PRL-2 Gene Expression in Normal Adult Human Tissues

Carmen M. Dumaual, George E. Sandusky, Pamela L. Crowell, Stephen K. Randall

J Histochem Cytochem. 2006 Dec; 54(12): 1401–1412. doi: 10.1369/jhc.6A7019.2006

PMCID:: PMC3958126

Abstract Article PDF–651K

Select item 32101239.

A Novel, Functional and Replicable Risk Gene Region for Alcohol Dependence Identified by Genome-Wide Association Study

Lingjun Zuo, Clarence K. Zhang, Fei Wang, Chiang-Shan R. Li, Hongyu Zhao, Lingeng Lu, Xiang-Yang Zhang, Lin Lu, Heping Zhang, Fengyu Zhang, John H. Krystal, Xingguang Luo

PLoS One. 2011; 6(11): e26726. Published online 2011 Nov 7. doi: 10.1371/journal.pone.0026726

PMCID:: PMC3210123

Abstract Article PDF–1.0M

Select item 565190610.

PTP4A1 promotes TGFβ signaling and fibrosis in systemic sclerosis

Cristiano Sacchetti, Yunpeng Bai, Stephanie M. Stanford, Paola Di Benedetto, Paola Cipriani, Eugenio Santelli, Sonsoles Piera-Velazquez, Vladimir Chernitskiy, William B. Kiosses, Arnold Ceponis, Klaus H. Kaestner, Francesco Boin, Sergio A. Jimenez, Roberto Giacomelli, Zhong-Yin Zhang, Nunzio Bottini

Nat Commun. 2017; 8: 1060. Published online 2017 Oct 20. doi: 10.1038/s41467-017-01168-1

PMCID:: PMC5651906

Abstract Article PDF–2.0M

Select item 493266711.

Suppression of cell migration is promoted by miR-944 through targeting of SIAH1 and PTP4A1 in breast cancer cells

Ali Flores-Pérez, Laurence A. Marchat, Sergio Rodríguez-Cuevas, Verónica Piña Bautista, Lizeth Fuentes-Mera, Diana Romero-Zamora, Anabel Maciel-Dominguez, Olga Hernández de la Cruz, Miguel Fonseca-Sánchez, Erika Ruíz-García, Horacio Astudillo-de la Vega, César López-Camarillo

BMC Cancer. 2016; 16: 379. Published online 2016 Jul 4. doi: 10.1186/s12885-016-2470-3

PMCID:: PMC4932667

Abstract Article PDF–1.1M

Select item 411125612.

Common PTP4A1-PHF3-EYS variants are specific for alcohol dependence

Lingjun Zuo, Kesheng Wang, Guilin Wang, Xinghua Pan, Xiangyang Zhang, Heping Zhang, Xingguang Luo

Am J Addict. Author manuscript; available in PMC 2014 Jul 25.

Published in final edited form as: Am J Addict. 2014 Jul; 23(4): 411–414. Published online 2013 Sep 13. doi: 10.1111/j.1521-0391.2013.12115.x

PMCID:: PMC4111256

Abstract Article PDF–76K

Select item 236063213.

Expression and prognostic impact of the protein tyrosine phosphatases PRL-1, PRL-2, and PRL-3 in breast cancer

I Radke, M Götte, C Kersting, B Mattsson, L Kiesel, P Wülfing

Br J Cancer. 2006 Aug 7; 95(3): 347–354. Published online 2006 Jul 11. doi: 10.1038/sj.bjc.6603261

PMCID:: PMC2360632

Abstract Article PDF–285K

Select item 359163414.

Tasuku Ishii, Yosuke Funato, Hiroaki Miki

J Biol Chem. 2013 Mar 8; 288(10): 7263–7270. Published online 2013 Jan 28. doi: 10.1074/jbc.M112.418004

PMCID:: PMC3591634

Abstract Article PDF–2.9M

Select item 276553815.

PRL1 promotes cell migration and invasion by increasing MMP2 and MMP9 expression through Src and ERK1/2 pathways

Yong Luo, Fubo Liang, Zhong-Yin Zhang

Biochemistry. Author manuscript; available in PMC 2010 Mar 3.

Published in final edited form as: Biochemistry. 2009 Mar 3; 48(8): 1838–1846. doi: 10.1021/bi8020789

PMCID:: PMC2765538

Abstract Article PDF–2.9M

Select item 13379816.

Tyrosine Phosphorylation Regulates Alpha II Spectrin Cleavage by Calpain

Gaël Nicolas, Catherine M. Fournier, Colette Galand, Laurence Malbert-Colas, Odile Bournier, Yolande Kroviarski, Monique Bourgeois, Jacques H. Camonis, Didier Dhermy, Bernard Grandchamp, Marie-Christine Lecomte

Mol Cell Biol. 2002 May; 22(10): 3527–3536. doi: 10.1128/MCB.22.10.3527-3536.2002

PMCID:: PMC133798

Abstract Article PDF–450K

Select item 617039317.

MYC-containing amplicons in acute myeloid leukemia: genomic structures, evolution, and transcriptional consequences

Alberto L′Abbate, Doron Tolomeo, Ingrid Cifola, Marco Severgnini, Antonella Turchiano, Bartolomeo Augello, Gabriella Squeo, Pietro D′Addabbo, Debora Traversa, Giulia Daniele, Angelo Lonoce, Mariella Pafundi, Massimo Carella, Orazio Palumbo, Anna Dolnik, Dominique Muehlematter, Jacqueline Schoumans, Nadine Van Roy, Gianluca De Bellis, Giovanni Martinelli, Giuseppe Merla, Lars Bullinger, Claudia Haferlach, Clelia Tiziana Storlazzi

Leukemia. 2018; 32(10): 2152–2166. Published online 2018 Feb 22. doi: 10.1038/s41375-018-0033-0

Correction in:: Leukemia. 2018; 32(10): 2304.

PMCID:: PMC6170393

Abstract Article PDF–2.4M

Select item 323493918.

PRL-1 Protein Promotes ERK1/2 and RhoA Protein Activation through a Non-canonical Interaction with the Src Homology 3 Domain of p115 Rho GTPase-activating Protein

Yunpeng Bai, Yong Luo, Sijiu Liu, Lujuan Zhang, Kui Shen, Yuanshu Dong, Chad D. Walls, Lawrence A. Quilliam, Clark D. Wells, Youjia Cao, Zhong-Yin Zhang

J Biol Chem. 2011 Dec 9; 286(49): 42316–42324. Published online 2011 Oct 18. doi: 10.1074/jbc.M111.286302

PMCID:: PMC3234939

Abstract Article PDF–2.2M

Select item 438322919.

Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression

Dmitry E Andreev, Patrick BF O'Connor, Ciara Fahey, Elaine M Kenny, Ilya M Terenin, Sergey E Dmitriev, Paul Cormican, Derek W Morris, Ivan N Shatsky, Pavel V Baranov

eLife. 2015; 4: e03971. Published online 2015 Jan 26. doi: 10.7554/eLife.03971

PMCID:: PMC4383229

Abstract Article PDF–3.4M

Select item 1024099820.

PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805

Yunpeng Bai, Guimei Yu, Hong-Ming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu, Qinglin Li, Lujuan Zhang, Frederick Nguele Meke, Yiming Miao, Eli Chapman, W. Andy Tao, Zhong-Yin Zhang

Autophagy. 2023; 19(5): 1562–1581. Published online 2022 Nov 7. doi: 10.1080/15548627.2022.2140558

PMCID:: PMC10240998

Abstract Article PDF–4.4M

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PMC Links for Gene (Select 7803) (44)
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Homo sapiens dynein regulatory complex subunit 7 (DRC7), transcript variant 1, m...
Homo sapiens dynein regulatory complex subunit 7 (DRC7), transcript variant 1, mRNA
gi|1653961989|ref|NM_001289162.2|

Nucleotide
RecName: Full=Translocon-associated protein subunit gamma; Short=TRAP-gamma; Alt...
RecName: Full=Translocon-associated protein subunit gamma; Short=TRAP-gamma; AltName: Full=Signal sequence receptor subunit gamma; Short=SSR-gamma
gi|62906894|sp|Q08013.2|SSRG_RAT

Protein

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