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Items: 1 to 20 of 68

1.
Human APOER2 Isoforms Have Differential Cleavage Events and Synaptic Properties
Kerilyn Casey Omuro, Christina M. Gallo, Lauren Scrandis, Angela Ho, Uwe Beffert
J Neurosci. 2022 May 18; 42(20): 4054–4068. doi: 10.1523/JNEUROSCI.1800-21.2022
PMCID:
PMC9121830
AbstractArticlePDF–4.3M
2.
Targeting LRP8 inhibits breast cancer stem cells in triple-negative breast cancer
Chang-Ching Lin, Miao-Chia Lo, Rebecca Moody, Hui Jiang, Ramdane Harouaka, Nicholas Stevers, Samantha Tinsley, Mari Gasparyan, Max Wicha, Duxin Sun
Cancer Lett. Author manuscript; available in PMC 2020 Jan 7.
Published in final edited form as: Cancer Lett. 2018 Dec 1; 438: 165–173. Published online 2018 Sep 15. doi: 10.1016/j.canlet.2018.09.022
Correction in:
Cancer Lett. 2020 Mar 27
PMCID:
PMC6945120
AbstractArticlePDF–1.8M
3.
LRP8 is overexpressed in estrogen‐negative breast cancers and a potential target for these tumors
Virginie Maire, Faisal Mahmood, Guillem Rigaill, Mengliang Ye, Amélie Brisson, Fariba Némati, David Gentien, Gordon C. Tucker, Sergio Roman‐Roman, Thierry Dubois
Cancer Med. 2019 Jan; 8(1): 325–336. Published online 2018 Dec 21. doi: 10.1002/cam4.1923
PMCID:
PMC6346259
AbstractArticlePDF–777K
4.
Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides
Anthony J Hinrich, Francine M Jodelka, Jennifer L Chang, Daniella Brutman, Angela M Bruno, Clark A Briggs, Bryan D James, Grace E Stutzmann, David A Bennett, Steven A Miller, Frank Rigo, Robert A Marr, Michelle L Hastings
EMBO Mol Med. 2016 Apr; 8(4): 328–345. Published online 2016 Feb 22. doi: 10.15252/emmm.201505846
PMCID:
PMC4818756
AbstractArticlePDF–2.4M
5.
A Novel Molecular Diagnostic Marker for Familial and Early-Onset CAD and MI in the LRP8 Gene
Gong-Qing Shen, Domenico Girelli, Lin Li, Shaoqi Rao, Stephen Archacki, Oliviero Olivieri, Nicola Martinelli, Jeong Euy Park, Qiuyun Chen, Eric J. Topol, Qing K. Wang
Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Aug 1.
Published in final edited form as: Circ Cardiovasc Genet. 2014 Aug; 7(4): 514–520. Published online 2014 May 27. doi: 10.1161/CIRCGENETICS.113.000321
PMCID:
PMC4140990
AbstractArticlePDF–702K
6.
Impaired lipoprotein receptor-mediated peripheral binding of plasma Aβ is an early biomarker for mild cognitive impairment preceding Alzheimer’s disease
Abhay P. Sagare, Rashid Deane, Henrik Zetterberg, Anders Wallin, Kaj Blennow, Berislav V. Zlokovic
J Alzheimers Dis. Author manuscript; available in PMC 2014 Jul 14.
Published in final edited form as: J Alzheimers Dis. 2011; 24(1): 25–34. doi: 10.3233/JAD-2010-101248
PMCID:
PMC4096563
AbstractArticlePDF–1.2M
7.
Multi-allelic haplotype association identifies novel information different from single-SNP analysis: A new protective haplotype in the LRP8 gene is against familial and early-onset CAD and MI
Gong-Qing Shen, Domenico Girelli, Lin Li, Oliviero Olivieri, Nicola Martinelli, Qiuyun Chen, Eric J. Topol, Qing K. Wang
Gene. Author manuscript; available in PMC 2014 Feb 10.
Published in final edited form as: Gene. 2013 May 25; 521(1): 78–81. Published online 2013 Mar 21. doi: 10.1016/j.gene.2013.03.022
PMCID:
PMC3919654
AbstractArticlePDF–84K
8.
Similarities and differences in structure, expression, and functions of VLDLR and ApoER2
Sunil S Reddy, Teal E Connor, Edwin J Weeber, William Rebeck
Mol Neurodegener. 2011; 6: 30. Published online 2011 May 9. doi: 10.1186/1750-1326-6-30
PMCID:
PMC3113299
AbstractArticlePDF–525K
9.
Additive effect of LRP8/APOER2 R952Q variant to APOE ε2/ε3/ε4 genotype in modulating apolipoprotein E concentration and the risk of myocardial infarction: a case-control study
Nicola Martinelli, Oliviero Olivieri, Gong-Qing Shen, Elisabetta Trabetti, Francesca Pizzolo, Fabiana Busti, Simonetta Friso, Antonella Bassi, Lin Li, Ying Hu, Pier Franco Pignatti, Roberto Corrocher, Qing Kenneth Wang, Domenico Girelli
BMC Med Genet. 2009; 10: 41. Published online 2009 May 13. doi: 10.1186/1471-2350-10-41
PMCID:
PMC2689206
AbstractArticlePDF–235K
10.
Polymorphism in Maternal LRP8 Gene Is Associated with Fetal Growth
Lin Wang, Xiaobin Wang, Nan Laird, Barry Zuckerman, Philip Stubblefield, Xin Xu
Am J Hum Genet. 2006 May; 78(5): 770–777. Published online 2006 Mar 10. doi: 10.1086/503712
PMCID:
PMC1474043
AbstractArticlePDF–120K
11.
Premature Myocardial Infarction Novel Susceptibility Locus on Chromosome 1P34-36 Identified by Genomewide Linkage Analysis
Qing Wang, Shaoqi Rao, Gong-Qing Shen, Lin Li, David J. Moliterno, L. Kristin Newby, William J. Rogers, Ruth Cannata, Erich Zirzow, Robert C. Elston, Eric J. Topol
Am J Hum Genet. 2004 Feb; 74(2): 262–271. Published online 2004 Jan 19. doi: 10.1086/381560
Correction in:
Am J Hum Genet. 2004 May; 74(5): 1080.
PMCID:
PMC1181924
AbstractArticlePDF–225K
12.
Spon1+ inflammatory monocytes promote collagen remodeling and lung cancer metastasis through lipoprotein receptor 8 signaling
Kristina M. Whately, Nisitha Sengottuvel, Lincy Edatt, Sonal Srivastava, Allison T. Woods, Yihsuan S. Tsai, Alessandro Porrello, Matthew P. Zimmerman, Aaron C. Chack, Stuart R. Jefferys, Gabriella Yacovone, Dae Joong Kim, Andrew C. Dudley, Antonio L. Amelio, Chad V. Pecot
JCI Insight. 2024 May 8; 9(9): e168792. Published online 2024 May 8. doi: 10.1172/jci.insight.168792
PMCID:
PMC11141919
AbstractArticlePDF–4.4M
13.
ApoER2-Dab1 disruption as the origin of pTau-associated neurodegeneration in sporadic Alzheimer’s disease
Christopher E. Ramsden, Daisy Zamora, Mark S. Horowitz, Jahandar Jahanipour, Elizabeth Calzada, Xiufeng Li, Gregory S. Keyes, Helen C. Murray, Maurice A. Curtis, Richard M. Faull, Andrea Sedlock, Dragan Maric
Acta Neuropathol Commun. 2023; 11: 197. Published online 2023 Dec 13. doi: 10.1186/s40478-023-01693-9
PMCID:
PMC10720169
AbstractArticlePDF–6.4M
14.
Single molecule, long-read Apoer2 sequencing identifies conserved and species-specific splicing patterns
Christina M. Gallo, Adam T. Labadorf, Angela Ho, Uwe Beffert
Genomics. Author manuscript; available in PMC 2023 Mar 1.
Published in final edited form as: Genomics. 2022 Mar; 114(2): 110318. Published online 2022 Feb 19. doi: 10.1016/j.ygeno.2022.110318
PMCID:
PMC8978334
AbstractArticlePDF–1.8M
15.
Differential Action of Reelin on Oligomerization of ApoER2 and VLDL Receptor in HEK293 Cells Assessed by Time-Resolved Anisotropy and Fluorescence Lifetime Imaging Microscopy
Paula Dlugosz, Roland Tresky, Johannes Nimpf
Front Mol Neurosci. 2019; 12: 53. Published online 2019 Feb 26. doi: 10.3389/fnmol.2019.00053
PMCID:
PMC6403468
AbstractArticlePDF–10M
16.
Structural basis for ligand capture and release by the endocytic receptor ApoER2
Hidenori Hirai, Norihisa Yasui, Keitaro Yamashita, Sanae Tabata, Masaki Yamamoto, Junichi Takagi, Terukazu Nogi
EMBO Rep. 2017 Jun; 18(6): 982–999. Published online 2017 Apr 26. doi: 10.15252/embr.201643521
PMCID:
PMC5452030
AbstractArticlePDF–2.8M
17.
Apolipoprotein E Receptor 2 mediates Activated Protein C-induced endothelial Akt activation and endothelial barrier stabilization
Ranjeet K. Sinha, Xia V. Yang, José A. Fernández, Xiao Xu, Laurent O. Mosnier, John H. Griffin
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Mar 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3): 518–524. Published online 2016 Jan 21. doi: 10.1161/ATVBAHA.115.306795
PMCID:
PMC4816599
AbstractArticlePDF–986K
18.
Sorting Nexin 17 Regulates ApoER2 Recycling and Reelin Signaling
Pablo Sotelo, Pamela Farfán, María Luisa Benitez, Guojun Bu, María-Paz Marzolo
PLoS One. 2014; 9(4): e93672. Published online 2014 Apr 4. doi: 10.1371/journal.pone.0093672
PMCID:
PMC3976305
AbstractArticlePDF–3.7M
19.
Exome-Wide Association Study of Replicable Nonsynonymous Variants Conferring Risk for Alcohol Dependence
Lingjun Zuo, Laura Saba, Kesheng Wang, Xiangyang Zhang, John H. Krystal, Boris Tabakoff, Xingguang Luo
J Stud Alcohol Drugs. 2013 Jul; 74(4): 622–625. doi: 10.15288/jsad.2013.74.622
PMCID:
PMC3711352
AbstractArticlePDF–136K
20.
An LRP8 Variant Is Associated with Familial and Premature Coronary Artery Disease and Myocardial Infarction
Gong-Qing  Shen, Lin  Li, Domenico  Girelli, Sara B.  Seidelmann, Shaoqi  Rao, Chun  Fan, Jeong Euy  Park, Quansheng  Xi, Jing  Li, Ying  Hu, Oliviero  Olivieri, Kandice  Marchant, John  Barnard, Roberto  Corrocher, Robert  Elston, June  Cassano, Susan  Henderson, Stanley L.  Hazen, Edward F.  Plow, Eric J.  Topol, Qing K.  Wang
Am J Hum Genet. 2007 Oct; 81(4): 780–791. Published online 2007 Aug 31. doi: 10.1086/521581
PMCID:
PMC2227927
AbstractArticlePDF–394K

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