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Select item 111589821.

Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer

Takuya Akashi, Keiichi Koizumi, Koichi Tsuneyama, Ikuo Saiki, Yasuo Takano, Hideki Fuse

Cancer Sci. 2008 Mar; 99(3): 539–542. Published online 2008 Jan 15. doi: 10.1111/j.1349-7006.2007.00712.x

PMCID:: PMC11158982

Abstract Article PDF–145K

Select item 111049132.

Inhibition of HIV replication through siRNA carried by CXCR4-targeted chimeric nanobody

Catarina Cunha-Santos, Pedro Ricardo Lucas Perdigao, Francisco Martin, Joana Gomes Oliveira, Miguel Cardoso, Ana Manuel, Nuno Taveira, Joao Goncalves

Cell Mol Life Sci. 2020 Jul; 77(14): 2859–2870. Published online 2019 Oct 22. doi: 10.1007/s00018-019-03334-8

PMCID:: PMC11104913

Abstract Article PDF–2.6M

Select item 109944153.

The CXCR4 might be a potential biomarker for esophageal squamous cell carcinoma: A meta-analysis

Pei Chen, Yu-Ling Zhang, Xiao-Lei Zhang, Ying Guo, Pei-Pei Tang

Medicine (Baltimore) 2024 Apr 5; 103(14): e37681. Published online 2024 Apr 5. doi: 10.1097/MD.0000000000037681

PMCID:: PMC10994415

Abstract Article PDF–930K

Select item 109603604.

Expression and clinical value of CXCR4 in high grade gastroenteropancreatic neuroendocrine neoplasms

Chaoyu Pang, Yongzheng Li, Ming Shi, Zhiyao Fan, Xin Gao, Yufan Meng, Shujie Liu, Changhao Gao, Peng Su, Xiao Wang, Hanxiang Zhan

Front Endocrinol (Lausanne) 2024; 15: 1281622. Published online 2024 Mar 8. doi: 10.3389/fendo.2024.1281622

PMCID:: PMC10960360

Abstract Article PDF–3.7M

Select item 109374465.

Intratumoral CXCR4^hi neutrophils display ferroptotic and immunosuppressive signatures in hepatoblastoma

Zhengjing Lu, Xiaolin Wang, Jun Feng, Wenjia Chai, Wei Wang, Qixin Wang, Shen Yang, Wei Yang, Yan Su, Wenjun Mou, Yun Peng, Huanmin Wang, Jingang Gui

Front Immunol. 2024; 15: 1363454. Published online 2024 Feb 29. doi: 10.3389/fimmu.2024.1363454

PMCID:: PMC10937446

Abstract Article PDF–14M

Select item 102454366.

Targeting CXCR4 abrogates resistance to trastuzumab by blocking cell cycle progression and synergizes with docetaxel in breast cancer treatment

Shuying Liu, Shelly M. Xie, Wenbin Liu, Mihai Gagea, Ariella B. Hanker, Nguyen Nguyen, Akshara Singareeka Raghavendra, Gloria Yang-Kolodji, Fuliang Chu, Sattva S. Neelapu, Adriano Marchese, Samir Hanash, Johann Zimmermann, Carlos L. Arteaga, Debasish Tripathy

Breast Cancer Res. 2023; 25: 62. Published online 2023 Jun 6. doi: 10.1186/s13058-023-01665-w

PMCID:: PMC10245436

Abstract Article PDF–7.0M

Select item 101593517.

The N-terminus of CXCR4 splice variants determines expression and functional properties

Hee-Kyung Park, Lan Phuong Nguyen, Thai Uy Nguyen, Minyeong Cho, Huong Thi Nguyen, Sunghoon Hurh, Hong-Rae Kim, Jae Young Seong, Cheol Soon Lee, Byung-Joo Ham, Jong-Ik Hwang

PLoS One. 2023; 18(5): e0283015. Published online 2023 May 4. doi: 10.1371/journal.pone.0283015

PMCID:: PMC10159351

Abstract Article PDF–2.1M

Select item 98412508.

C-X-C Motif Chemokine Receptor 4–Targeted Radioligand Therapy in Patients with Advanced T-Cell Lymphoma

Andreas K. Buck, Götz Ulrich Grigoleit, Sabrina Kraus, Andreas Schirbel, Michael Heinsch, Niklas Dreher, Takahiro Higuchi, Constantin Lapa, Heribert Hänscheid, Samuel Samnick, Hermann Einsele, Sebastian E. Serfling, Rudolf A. Werner

J Nucl Med. 2023 Jan; 64(1): 34–39. doi: 10.2967/jnumed.122.264207

PMCID:: PMC9841250

Abstract Article PDF–775K

Select item 96651359.

Aberrant regulation of CXCR4 in cancer via deviant microRNA-targeted interactions

Alexei J. Stuckel, Tripti Khare, Marc Bissonnette, Sharad Khare

Epigenetics. 2022; 17(13): 2318–2331. Published online 2022 Sep 6. doi: 10.1080/15592294.2022.2118947

PMCID:: PMC9665135

Abstract Article PDF–389K

Select item 966054310.

Multi-omic Characterization of Pancreatic Ductal Adenocarcinoma Relates CXCR4 mRNA Expression Levels to Potential Clinical Targets

Florian Kocher, Alberto Puccini, Gerold Untergasser, Agnieszka Martowicz, Kai Zimmer, Andreas Pircher, Yasmine Baca, Joanne Xiu, Johannes Haybaeck, Piotr Tymoszuk, Richard M. Goldberg, Angelica Petrillo, Anthony F. Shields, Mohamed E. Salem, John L. Marshall, Michael Hall, W. Michael Korn, Chadi Nabhan, Francesca Battaglin, Heinz-Josef Lenz, Emil Lou, Su-Pin Choo, Chee-Keong Toh, Silvia Gasteiger, Renate Pichler, Dominik Wolf, Andreas Seeber

Clin Cancer Res. 2022 Nov 14; 28(22): 4957–4967. Published online 2022 Sep 16. doi: 10.1158/1078-0432.CCR-22-0275

PMCID:: PMC9660543

Abstract Article PDF–1.4M

Select item 951944211.

Genotype–phenotype correlations in WHIM syndrome: a systematic characterization of CXCR4^WHIM variants

Katarina Zmajkovicova, Sumit Pawar, Sabine Maier-Munsa, Barbara Maierhofer, Ivana Wiest, Renato Skerlj, Arthur G. Taveras, Adriana Badarau

Genes Immun. 2022; 23(6): 196–204. Published online 2022 Sep 12. doi: 10.1038/s41435-022-00181-9

PMCID:: PMC9519442

Abstract Article PDF–1.3M

Select item 926105012.

Comparative evaluation of somatostatin and CXCR4 receptor expression in different types of thyroid carcinoma using well-characterised monoclonal antibodies

Max Czajkowski, Daniel Kaemmerer, Jörg Sänger, Guido Sauter, Ralph M. Wirtz, Stefan Schulz, Amelie Lupp

BMC Cancer. 2022; 22: 740. Published online 2022 Jul 7. doi: 10.1186/s12885-022-09839-z

PMCID:: PMC9261050

Abstract Article PDF–1.7M

Select item 921061713.

The clinicopathological and prognostic value of CXCR4 expression in patients with lung cancer: a meta-analysis

Liping Qiu, Yuanyuan Xu, Hui Xu, Biyun Yu

BMC Cancer. 2022; 22: 681. Published online 2022 Jun 21. doi: 10.1186/s12885-022-09756-1

PMCID:: PMC9210617

Abstract Article PDF–2.8M

Select item 917376014.

Altered CXCR4 dynamics at the cell membrane impairs directed cell migration in WHIM syndrome patients

Eva M. García-Cuesta, José Miguel Rodríguez-Frade, Sofía R. Gardeta, Gianluca D’Agostino, Pablo Martínez, Blanca Soler Palacios, Graciela Cascio, Tobias Wolf, Nicolas Mateos, Rosa Ayala-Bueno, César A. Santiago, Pilar Lucas, Lucia Llorente, Luis M. Allende, Luis Ignacio González-Granado, Noa Martín-Cófreces, Pedro Roda-Navarro, Federica Sallusto, Francisco Sánchez-Madrid, María F. García-Parajo, Laura Martínez-Muñoz, Mario Mellado

Proc Natl Acad Sci U S A. 2022 May 24; 119(21): e2119483119. Published online 2022 May 19. doi: 10.1073/pnas.2119483119

PMCID:: PMC9173760

Abstract Article PDF–2.2M

Select item 911305615.

Bone marrow involvement and subclonal diversity impairs detection of mutated CXCR4 by diagnostic next generation sequencing in Waldenström macroglobulinemia

Joshua N. Gustine, Lian Xu, Guang Yang, Xia Liu, Amanda Kofides, Nicholas Tsakmaklis, Manit Munshi, Maria Demos, Maria Luisa Guerrera, Kirsten Meid, Christopher J. Patterson, Shayna Sarosiek, Andrew R. Branagan, Zachary R. Hunter, Jorge J. Castillo, Steven P. Treon

Br J Haematol. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: Br J Haematol. 2021 Aug; 194(4): 730–733. Published online 2021 Mar 13. doi: 10.1111/bjh.17385

PMCID:: PMC9113056

Abstract Article PDF–342K

Select item 909023616.

Differential CXCR4 expression on hematopoietic progenitor cells versus stem cells directs homing and engraftment

Sydney Felker, Archana Shrestha, Jeff Bailey, Devin M Pillis, Dylan Siniard, Punam Malik

JCI Insight. 2022 May 9; 7(9): e151847. Published online 2022 May 9. doi: 10.1172/jci.insight.151847

PMCID:: PMC9090236

Abstract Article PDF–2.5M

Select item 899423217.

High ratio of pCXCR4/CXCR4 tumor infiltrating immune cells in primary high grade ovarian cancer is indicative for response to chemotherapy

Fabio Walther, Jana Ladina Berther, Alexandros Lalos, Michaela Ramser, Simone Eichelberger, Robert Mechera, Savas Soysal, Simone Muenst, Alberto Posabella, Uwe Güth, Sylvia Stadlmann, Luigi Terracciano, Raoul A. Droeser, Jasmin Zeindler, Gad Singer

BMC Cancer. 2022; 22: 376. Published online 2022 Apr 9. doi: 10.1186/s12885-022-09374-x

PMCID:: PMC8994232

Abstract Article PDF–1.3M

Select item 898687418.

Characteristics of immunophenotypes and immunological in tumor microenvironment and analysis of immune implication of CXCR4 in gastric cancer

Fang Wen, Xiaona Lu, Wenjie Huang, Xiaoxue Chen, Shuai Ruan, SuPing Gu, Peixing Gu, Ye Li, Jiatong Liu, Shenlin Liu, Peng Shu

Sci Rep. 2022; 12: 5720. Published online 2022 Apr 6. doi: 10.1038/s41598-022-08622-1

PMCID:: PMC8986874

Abstract Article PDF–13M

Select item 897290919.

Dysregulated Expression of CXCR4/CXCL12 in Subsets of Patients with Systemic Lupus Erythematosus

Andrew Wang, Philippe Guilpain, Benjamin F. Chong, Sandrine Chouzenoux, Loïc Guillevin, Yong Du, Xin J. Zhou, Fangming Lin, Anna-Marie Fairhurst, Christopher Boudreaux, Christian Roux, Edward K. Wakeland, Laurie Davis, Frederic Batteux, Chandra Mohan

Arthritis Rheum. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Arthritis Rheum. 2010 Nov; 62(11): 3436–3446. doi: 10.1002/art.27685

PMCID:: PMC8972909

Abstract Article PDF–735K

Select item 890325620.

CXCR4 expression in tumor associated cells in blood is prognostic for progression and survival in pancreatic cancer

Kirby P. Gardner, Susan Tsai, Mohammed Aldakkak, Stephen Gironda, Daniel L. Adams

PLoS One. 2022; 17(3): e0264763. Published online 2022 Mar 8. doi: 10.1371/journal.pone.0264763

PMCID:: PMC8903256

Abstract Article PDF–1.6M

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