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Select item 110586681.

Expression of human dCTP pyrophosphatase 1 (DCTPP1) and its association with cisplatin resistance characteristics in ovarian cancer

Yu Wang, Xiangyun Chen, Qiduan Chen, Tiancai Liu, Yingsong Wu, Liping Huang, Yao Chen

J Cell Mol Med. 2024 May; 28(9): e18371. Published online 2024 Apr 30. doi: 10.1111/jcmm.18371

PMCID:: PMC11058668

Abstract Article PDF–26M

Select item 71628422.

DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools

Blanca Martínez-Arribas, Cristina E. Requena, Guiomar Pérez-Moreno, Luis M. Ruíz-Pérez, Antonio E. Vidal, Dolores González-Pacanowska

Cell Mol Life Sci. 2020 Apr; 77(8): 1645–1660. Published online 2019 Aug 3. doi: 10.1007/s00018-019-03250-x

PMCID:: PMC7162842

Abstract Article PDF–4.6M

Select item 44916113.

Human dCTP pyrophosphatase 1 promotes breast cancer cell growth and stemness through the modulation on 5-methyl-dCTP metabolism and global hypomethylation

F-f Song, L-l Xia, P Ji, Y-b Tang, Z-m Huang, L Zhu, J Zhang, J-q Wang, G-p Zhao, H-l Ge, Y Zhang, Y Wang

Oncogenesis. 2015 Jun; 4(6): e159. Published online 2015 Jun 15. doi: 10.1038/oncsis.2015.10

PMCID:: PMC4491611

Abstract Article PDF–5.0M

Select item 37943604.

dCTP Pyrophosphohydrase Exhibits Nucleic Accumulation in Multiple Carcinomas

Y. Zhang, W.Y. Ye, J.Q. Wang, S.J. Wang, P. Ji, G.Y. Zhou, G.P. Zhao, H.L. Ge, Y. Wang

Eur J Histochem. 2013 Sep 27; 57(3): e29. Published online 2013 Sep 25. doi: 10.4081/ejh.2013.e29

PMCID:: PMC3794360

Abstract Article PDF–479K

Select item 35035175.

Triptolide Directly Inhibits dCTP Pyrophosphatase

Dr. Timothy W. Corson, Dr. Hüseyin Cavga, Dr. Nicholas Aberle, Craig M. Crews

Chembiochem. Author manuscript; available in PMC 2012 Nov 21.

Published in final edited form as: Chembiochem. 2011 Jul 25; 12(11): 1767–1773. Published online 2011 Jun 10. doi: 10.1002/cbic.201100007

PMCID:: PMC3503517

Abstract Article PDF–1.0M

Select item 53565786.

DCTPP1 attenuates the sensitivity of human gastric cancer cells to 5-fluorouracil by up-regulating MDR1 expression epigenetically

Li-liang Xia, Ya-bin Tang, Fei-fei Song, Ling Xu, Ping Ji, Shu-jun Wang, Ji-min Zhu, Yong Zhang, Guo-ping Zhao, Ying Wang, Tao-tao Liu

Oncotarget. 2016 Oct 18; 7(42): 68623–68637. Published online 2016 Sep 6. doi: 10.18632/oncotarget.11864

PMCID:: PMC5356578

Abstract Article PDF–5.2M

Select item 74254427.

Silencing DSCAM-AS1 suppresses the growth and invasion of ER-positive breast cancer cells by downregulating both DCTPP1 and QPRT

Zhang Yue, Jia Shusheng, Song Hongtao, Zhao Shu, Huang Lan, Zhang Qingyuan, Cheng Shaoqiang, Huang Yuanxi

Aging (Albany NY) 2020 Jul 31; 12(14): 14754–14774. Published online 2020 Jul 27. doi: 10.18632/aging.103538

Correction in:: Aging (Albany NY). 2022 Jan 15; 14(1): 528–529.

PMCID:: PMC7425442

Abstract Article PDF–3.9M

Select item 27206868.

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

Jennifer M. Svendsen, Agata Smogorzewska, Mathew E. Sowa, Brenda C. O’Connell, Steven P. Gygi, Stephen J. Elledge, J. Wade Harper

Cell. Author manuscript; available in PMC 2010 Jan 10.

Published in final edited form as: Cell. 2009 Jul 10; 138(1): 63–77. doi: 10.1016/j.cell.2009.06.030

PMCID:: PMC2720686

Abstract Article PDF–6.1M

Select item 43527079.

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization

Stephanie J Papp, Anne-Laure Huber, Sabine D Jordan, Anna Kriebs, Madelena Nguyen, James J Moresco, John R Yates, III, Katja A Lamia

eLife. 2015; 4: e04883. Published online 2015 Mar 10. doi: 10.7554/eLife.04883

PMCID:: PMC4352707

Abstract Article PDF–3.4M

Select item 397941110.

Characterizing WW Domain Interactions of Tumor Suppressor WWOX Reveals Its Association with Multiprotein Networks

Mohammad Abu-Odeh, Tomer Bar-Mag, Haiming Huang, TaeHyung Kim, Zaidoun Salah, Suhaib K. Abdeen, Marius Sudol, Dana Reichmann, Sachdev Sidhu, Philip M. Kim, Rami I. Aqeilan

J Biol Chem. 2014 Mar 28; 289(13): 8865–8880. Published online 2014 Feb 18. doi: 10.1074/jbc.M113.506790

PMCID:: PMC3979411

Abstract Article PDF–3.0M

Select item 794845211.

A conserved acetylation switch enables pharmacological control of tubby-like protein stability

Evan M. Kerek, Kevin H. Yoon, Shu Y. Luo, Jerry Chen, Robert Valencia, Olivier Julien, Andrew J. Waskiewicz, Basil P. Hubbard

J Biol Chem. 2021 Jan-Jun; 296: 100073. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015839

PMCID:: PMC7948452

Abstract Article PDF–3.6M

Select item 761053512.

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase

Bikash Adhikari, Jelena Bozilovic, Mathias Diebold, Jessica Denise Schwarz, Julia Hofstetter, Martin Schröder, Marek Wanior, Ashwin Narain, Markus Vogt, Nevenka Dudvarski Stankovic, Apoorva Baluapuri, Lars Schönemann, Lorenz Eing, Pranjali Bhandare, Bernhard Kuster, Andreas Schlosser, Stephanie Heinzlmeir, Christoph Sotriffer, Stefan Knapp, Elmar Wolf

Nat Chem Biol. Author manuscript; available in PMC 2021 Apr 6.

Published in final edited form as: Nat Chem Biol. 2020 Nov 1; 16(11): 1179–1188. Published online 2020 Sep 28. doi: 10.1038/s41589-020-00652-y

PMCID:: PMC7610535

Abstract Article PDF–5.1M

Select item 730149913.

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease

Ruinan Shen, Xiaobei Zhao, Lu He, Yongbo Ding, Wei Xu, Suzhen Lin, Savannah Fang, Wanlin Yang, Kijung Sung, Brian Spencer, Robert A. Rissman, Ming Lei, Jianqing Ding, Chengbiao Wu

Transl Neurodegener. 2020; 9: 26. Published online 2020 Jun 18. doi: 10.1186/s40035-020-00206-1

PMCID:: PMC7301499

Abstract Article PDF–14M

Select item 316943214.

Protein interactome reveals converging molecular pathways among autism disorders

Yasunari Sakai, Chad A. Shaw, Brian C. Dawson, Diana V. Dugas, Zaina Al-Mohtaseb, David E. Hill, Huda Y. Zoghbi

Sci Transl Med. Author manuscript; available in PMC 2011 Dec 8.

Published in final edited form as: Sci Transl Med. 2011 Jun 8; 3(86): 86ra49. doi: 10.1126/scitranslmed.3002166

PMCID:: PMC3169432

Abstract Article PDF–6.0M

Select item 574645515.

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals Molecular Determinants of Redox Homeostasis and NF-κB Signaling

Ramy H. Malty, Hiroyuki Aoki, Ashwani Kumar, Sadhna Phanse, Shahreen Amin, Qingzhou Zhang, Zoran Minic, Florian Goebels, Gabriel Musso, Zhuoran Wu, Hosam Abou-tok, Michael Meyer, Viktor Deineko, Sandy Kassir, Vishaldeep Sidhu, Matthew Jessulat, Nichollas E. Scott, Xuejian Xiong, James Vlasblom, Bhanu Prasad, Leonard J. Foster, Tiziana Alberio, Barbara Garavaglia, Haiyuan Yu, Gary D. Bader, Ken Nakamura, John Parkinson, Mohan Babu

Cell Syst. Author manuscript; available in PMC 2018 Dec 27.

Published in final edited form as: Cell Syst. 2017 Dec 27; 5(6): 564–577.e12. Published online 2017 Nov 8. doi: 10.1016/j.cels.2017.10.010

PMCID:: PMC5746455

Abstract Article PDF–3.3M

Select item 563060016.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

Select item 501331517.

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family

Xu Li, Kim My Tran, Kathryn E. Aziz, Alexey V. Sorokin, Junjie Chen, Wenqi Wang

Mol Cell Proteomics. 2016 Sep; 15(9): 3030–3044. Published online 2016 Jul 18. doi: 10.1074/mcp.M116.060277

PMCID:: PMC5013315

Abstract Article PDF–3.2M

Select item 554841318.

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling

Parveen Kumar, Prathyusha Munnangi, KVS Rammohan Chowdary, Varun J. Shah, Swapnil R. Shinde, Nanci R. Kolli, Rachita R. Halehalli, Hampapathalu A. Nagarajaram, Subbareddy Maddika

J Proteome Res. 2017 Aug 4; 16(8): 2789–2801. Published online 2017 Jul 4. doi: 10.1021/acs.jproteome.7b00065

PMCID:: PMC5548413

Abstract Article PDF–5.2M

Select item 484875819.

An inter‐species protein–protein interaction network across vast evolutionary distance

Quan Zhong, Samuel J Pevzner, Tong Hao, Yang Wang, Roberto Mosca, Jörg Menche, Mikko Taipale, Murat Taşan, Changyu Fan, Xinping Yang, Patrick Haley, Ryan R Murray, Flora Mer, Fana Gebreab, Stanley Tam, Andrew MacWilliams, Amélie Dricot, Patrick Reichert, Balaji Santhanam, Lila Ghamsari, Michael A Calderwood, Thomas Rolland, Benoit Charloteaux, Susan Lindquist, Albert‐László Barabási, David E Hill, Patrick Aloy, Michael E Cusick, Yu Xia, Frederick P Roth, Marc Vidal

Mol Syst Biol. 2016 Apr; 12(4): 865. Published online 2016 Apr 23. doi: 10.15252/msb.20156484

PMCID:: PMC4848758

Abstract Article PDF–2.1M

Select item 903609220.

Tumor suppressor BAP1 nuclear import is governed by transportin-1

Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu

J Cell Biol. 2022 Jun 6; 221(6): e202201094. Published online 2022 Apr 21. doi: 10.1083/jcb.202201094

PMCID:: PMC9036092

Abstract Article PDF–4.0M

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PMC Links for Gene (Select 79077) (36)
PMC
rap guanine nucleotide exchange factor 4 isoform h [Homo sapiens]
rap guanine nucleotide exchange factor 4 isoform h [Homo sapiens]
gi|1772791022|ref|NP_001362795.1|

Protein
PREDICTED: Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), tran...
PREDICTED: Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X2, mRNA
gi|2217325129|ref|XM_047443028.1|

Nucleotide
dCTP pyrophosphatase 1 [Homo sapiens]
dCTP pyrophosphatase 1 [Homo sapiens]
gi|13129100|ref|NP_077001.1|

Protein

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