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Select item 109846621.

FAT4 loss initiates hepatocarcinogenesis through the switching of canonical to noncanonical WNT signaling pathways

Fung-Yu Huang, Danny Ka-Ho Wong, Lung-Yi Mak, Tan-To Cheung, Sai-Sai Zhang, Hau-Tak Chau, Rex Wan-Hin Hui, Wai-Kay Seto, Man-Fung Yuen

Hepatol Commun. 2023 Dec; 7(12): e0338. Published online 2023 Dec 7. doi: 10.1097/HC9.0000000000000338

PMCID:: PMC10984662

Abstract Article PDF–1.9M

Select item 105431452.

Identification of FAT4 as a positive prognostic biomarker in DLBCL by comprehensive genomic analysis

Liyang Lv, Xiaolong Qi, Chun Wang, Yutong Ma, Yuling Nie, Renaguli Abulaiti, Fang Zhang, Qiping Shi, Zhen Kou, Muhebaier Abuduer, Shunsheng Zhai, Li An, Qin Huang, Zailinuer Gu, Qiuxiang Ou, Hong Liu, Zengsheng Wang, Yang Shao, Zhenzhu Sun, Ling Fu, Xiaomin Wang, Min Mao, Yan Li

Clin Exp Med. 2023; 23(6): 2675–2685. Published online 2023 Feb 22. doi: 10.1007/s10238-023-01018-z

PMCID:: PMC10543145

Abstract Article PDF–4.3M

Select item 98834283.

Increased expression of FAT4 suppress metastasis of lung adenocarcinoma through regulating MAPK pathway and associated with immune cells infiltration

Yue Ning, Yang Yang, Hongmei Zheng, Yuting Zhan, Hongjing Zang, Qiuyuan Wen, Jinwu Peng, Songqing Fan

Cancer Med. 2023 Jan; 12(2): 1616–1629. Published online 2022 Jun 30. doi: 10.1002/cam4.4977

PMCID:: PMC9883428

Abstract Article PDF–26M

Select item 94245484.

A pan-cancer analysis of FAT atypical cadherin 4 (FAT4) in human tumors

Weili Mao, Jiajing Zhou, Jie Hu, Kui Zhao, Zhenling Fu, Jun Wang, Kaili Mao

Front Public Health. 2022; 10: 969070. Published online 2022 Aug 16. doi: 10.3389/fpubh.2022.969070

PMCID:: PMC9424548

Abstract Article PDF–6.2M

Select item 86308275.

FAT4 Identified as a Potential Modifier of Orofacial Cleft Laterality

Sarah W. Curtis, Daniel Chang, Miranda R. Sun, Michael P. Epstein, Jeffrey C. Murray, Eleanor Feingold, Terri H. Beaty, Seth M. Weinberg, Mary L. Marazita, Robert J. Lipinski, Jenna C. Carlson, Elizabeth J. Leslie

Genet Epidemiol. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Genet Epidemiol. 2021 Oct; 45(7): 721–735. Published online 2021 Jun 15. doi: 10.1002/gepi.22420

PMCID:: PMC8630827

Abstract Article PDF–1.2M

Select item 66865556.

Targeted genomic profiling identifies frequent deleterious mutations in FAT4 and TP53 genes in HBV-associated hepatocellular carcinoma

Fung-Yu Huang, Danny Ka-Ho Wong, Vivien Wai-Man Tsui, Wai-Kay Seto, Lung-Yi Mak, Tan-To Cheung, Keane K.-Y. Lai, Man-Fung Yuen

BMC Cancer. 2019; 19: 789. Published online 2019 Aug 8. doi: 10.1186/s12885-019-6002-9

PMCID:: PMC6686555

Abstract Article PDF–2.6M

Select item 63999647.

FAT4 regulates the EMT and autophagy in colorectal cancer cells in part via the PI3K-AKT signaling axis

Ran Wei, Yuhong Xiao, Yi Song, Huiping Yuan, Jun Luo, Wei Xu

J Exp Clin Cancer Res. 2019; 38: 112. Published online 2019 Mar 4. doi: 10.1186/s13046-019-1043-0

PMCID:: PMC6399964

Abstract Article PDF–6.3M

Select item 48230778.

Inferring the progression of multifocal liver cancer from spatial and temporal genomic heterogeneity

Jie-Yi Shi, Qingfeng Xing, Meng Duan, Zhi-Chao Wang, Liu-Xiao Yang, Ying-Jun Zhao, Xiao-Ying Wang, Yun Liu, Minghua Deng, Zhen-Bin Ding, Ai-Wu Ke, Jian Zhou, Jia Fan, Ya Cao, Jiping Wang, Ruibin Xi, Qiang Gao

Oncotarget. 2016 Jan 19; 7(3): 2867–2877. Published online 2015 Dec 11. doi: 10.18632/oncotarget.6558

PMCID:: PMC4823077

Abstract Article PDF–5.4M

Select item 47019929.

FAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/β-catenin signalling

Jian Cai, Dan Feng, Liang Hu, Haiyang Chen, Guangzhen Yang, Qingping Cai, Chunfang Gao, Dong Wei

Br J Cancer. 2015 Dec 22; 113(12): 1720–1729. Published online 2015 Dec 3. doi: 10.1038/bjc.2015.367

PMCID:: PMC4701992

Abstract Article PDF–2.0M

Select item 433452210.

Inhibitory Mechanism of FAT4 Gene Expression in Response to Actin Dynamics during Src-Induced Carcinogenesis

Takao Ito, Hiroaki Taniguchi, Kousuke Fukagai, Shota Okamuro, Akira Kobayashi

PLoS One. 2015; 10(2): e0118336. Published online 2015 Feb 13. doi: 10.1371/journal.pone.0118336

PMCID:: PMC4334522

Abstract Article PDF–3.3M

Select item 993587611.

Structure of the planar cell polarity cadherins Fat4 and Dachsous1

Elliot Medina, Yathreb Easa, Daniel K. Lester, Eric K. Lau, David Sprinzak, Vincent C. Luca

Nat Commun. 2023; 14: 891. Published online 2023 Feb 16. doi: 10.1038/s41467-023-36435-x

PMCID:: PMC9935876

Abstract Article PDF–2.8M

Select item 760719212.

MiR-106b-5p regulates the migration and invasion of colorectal cancer cells by targeting FAT4

Min Pan, Qiuqiu Chen, Yusong Lu, Feifei Wei, Chunqiao Chen, Guiyan Tang, Hui Huang

Biosci Rep. 2020 Nov 27; 40(11): BSR20200098. Published online 2020 Nov 2. doi: 10.1042/BSR20200098

Expression of Concern in:: Biosci Rep. 2021 Apr 30; 41(4): BSR-20200098_EOC.

PMCID:: PMC7607192

Abstract Article PDF–4.3M

Select item 655664113.

FAT4-USP51 complex regulates the proliferation and invasion of endometrial cancer via Hippo pathway

Xiaoxia Che, Fangfang Jian, Nan Jia, Ya Zheng, Yahui Jiang, Weiwei Feng

Am J Transl Res. 2019; 11(5): 2784–2800. Published online 2019 May 15.

PMCID:: PMC6556641

Abstract Article PDF–9.5M

Select item 557692014.

A synthetic planar cell polarity system reveals localized feedback on Fat4-Ds1 complexes

Olga Loza, Idse Heemskerk, Nadav Gordon-Bar, Liat Amir-Zilberstein, Yunmin Jung, David Sprinzak

eLife. 2017; 6: e24820. Published online 2017 Aug 18. doi: 10.7554/eLife.24820

PMCID:: PMC5576920

Abstract Article PDF–3.2M

Select item 484781915.

Fat4 suppression induces Yap translocation accounting for the promoted proliferation and migration of gastric cancer cells

Liangang Ma, Jianxin Cui, Hongqing Xi, Shibo Bian, Bo Wei, Lin Chen

Cancer Biol Ther. 2016 Jan; 17(1): 36–47. Published online 2015 Nov 17. doi: 10.1080/15384047.2015.1108488

PMCID:: PMC4847819

Abstract Article PDF–1.4M

Select item 266715616.

Identification of Fat4 as a candidate tumor suppressor gene in breast cancers

Chao Qi, Yiwei Tony Zhu, Liping Hu, Yi-Jun Zhu

Int J Cancer. Author manuscript; available in PMC 2010 Feb 15.

Published in final edited form as: Int J Cancer. 2009 Feb 15; 124(4): 793–798. doi: 10.1002/ijc.23775

PMCID:: PMC2667156

Abstract Article PDF–580K

Select item 719712817.

FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and β-catenin activity in ovarian cancer

Shika Hanif Malgundkar, Ikram Burney, Mansour Al Moundhri, Moza Al Kalbani, Ritu Lakhtakia, Aikou Okamoto, Yahya Tamimi

BMC Cancer. 2020; 20: 374. Published online 2020 May 4. doi: 10.1186/s12885-020-06900-7

PMCID:: PMC7197128

Abstract Article PDF–1.2M

Select item 423454618.

Giant cadherins Fat and Dachsous self-bend to organize properly spaced intercellular junctions

Yoshikazu Tsukasaki, Naoyuki Miyazaki, Atsushi Matsumoto, Shigenori Nagae, Shigenobu Yonemura, Takuji Tanoue, Kenji Iwasaki, Masatoshi Takeichi

Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45): 16011–16016. Published online 2014 Oct 29. doi: 10.1073/pnas.1418990111

PMCID:: PMC4234546

Abstract Article PDF–1.5M

Select item 388362719.

Meta-Analysis of Genome-Wide Association Data of Bipolar Disorder and Major Depressive Disorder

Youfang Liu, Douglas H. Blackwood, Sian Caesar, Eco J.C. de Geus, Anne Farmer, Manuel A. R. Ferreira, I. Nicol Ferrier, Christing Fraser, Katherine Gordon-Smith, Elaine K. Green, Detelina Grozeva, Hugh M. Gurling, Marian L. Hamshere, Peter Heutink, Peter A. Holmans, Witte J. Hoogendijk, Jouke Jan Hottenga, Lisa Jones, Ian R. Jones, George Kirov, Danyu Lin, Peter McGuffin, Valentina Moskvina, Willem A. Nolen, Roy H. Perlis, Danielle Posthuma, Edward M. Scolnick, August B. Smit, Johannes H. Smit, Jordan W. Smoller, David St. Clair, Richard van Dyck, Matthijs Verhage, Wellcome Trust Case-Control Consortium, Gonneke Willemsen, Allan H. Young, Tim Zandbelt, Dorret I. Boomsma, Nick Craddock, Michael C. O’Donovan, Michael J. Owen, Brenda W.J.H. Penninx, Shaun Purcell, Pamela Sklar, Patrick F. Sullivan

Mol Psychiatry. Author manuscript; available in PMC 2014 Jan 7.

Published in final edited form as: Mol Psychiatry. 2011 Jan; 16(1): 10.1038/mp.2009.107. Published online 2010 Mar 30. doi: 10.1038/mp.2009.107

PMCID:: PMC3883627

Article PDF–190K

Select item 386272720.

Whole Exome Sequencing Identifies Novel Recurrently Mutated Genes in Patients with Splenic Marginal Zone Lymphoma

Marina Parry, Matthew J. J. Rose-Zerilli, Jane Gibson, Sarah Ennis, Renata Walewska, Jade Forster, Helen Parker, Zadie Davis, Anne Gardiner, Andrew Collins, David G. Oscier, Jonathan C. Strefford

PLoS One. 2013; 8(12): e83244. Published online 2013 Dec 13. doi: 10.1371/journal.pone.0083244

PMCID:: PMC3862727

Abstract Article PDF–256K

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