PMC Links for Gene (Select 79677) - PMC

Diego Serrano, Gustavo Cordero, Ryo Kawamura, Aleksandr Sverzhinsky, Muzaddid Sarker, Shamayita Roy, Catherine Malo, John M. Pascal, John F. Marko, Damien D’Amours

Mol Cell. Author manuscript; available in PMC 2021 Dec 17.

Published in final edited form as: Mol Cell. 2020 Dec 17; 80(6): 1025–1038.e5. Published online 2020 Dec 9. doi: 10.1016/j.molcel.2020.11.011

PMCID:: PMC8224240

Abstract Article PDF–2.5M

Select item 70015104.

SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability

Francesco Rossi, Anne Helbling‐Leclerc, Ryotaro Kawasumi, Nanda Kumar Jegadesan, Xinlin Xu, Pierre Devulder, Takuya Abe, Minoru Takata, Dongyi Xu, Filippo Rosselli, Dana Branzei

EMBO Rep. 2020 Feb 5; 21(2): e48222. Published online 2019 Dec 23. doi: 10.15252/embr.201948222

PMCID:: PMC7001510

Abstract Article PDF–1.6M

Select item 60522965.

The SMC5/6 Complex Interacts with the Papillomavirus E2 Protein and Influences Maintenance of Viral Episomal DNA

Peris Bentley, Min Jie Alvin Tan, Alison A. McBride, Elizabeth A. White, Peter M. Howley

J Virol. 2018 Aug 1; 92(15): e00356-18. Prepublished online 2018 May 30. Published online 2018 Jul 17. doi: 10.1128/JVI.00356-18

PMCID:: PMC6052296

Abstract Article PDF–2.1M

Select item 38903506.

Smc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells

Lina Marcela Gallego-Paez, Hiroshi Tanaka, Masashige Bando, Motoko Takahashi, Naohito Nozaki, Ryuichiro Nakato, Katsuhiko Shirahige, Toru Hirota

Mol Biol Cell. 2014 Jan 15; 25(2): 302–317. doi: 10.1091/mbc.E13-01-0020

PMCID:: PMC3890350

Abstract Article PDF–5.8M

Select item 112944467.

The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress

Dylan F Fingerman, David R O’Leary, Ava R Hansen, Thi Tran, Brooke R Harris, Rachel A DeWeerd, Katharina E Hayer, Jiayi Fan, Emily Chen, Mithila Tennakoon, Alice Meroni, Julia H Szeto, Jessica Devenport, Danielle LaVigne, Matthew D Weitzman, Ophir Shalem, Jeffrey Bednarski, Alessandro Vindigni, Xiaolan Zhao, Abby M Green

EMBO J. 2024 Aug; 43(15): 3240–3255. Published online 2024 Jun 17. doi: 10.1038/s44318-024-00137-x

PMCID:: PMC11294446

Abstract Article PDF–9.0M

Select item 81186238.

The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr

Liane Dupont, Stuart Bloor, James C. Williamson, Sergio Martínez Cuesta, Raven Shah, Ana Teixeira-Silva, Adi Naamati, Edward J.D. Greenwood, Stefan G. Sarafianos, Nicholas J. Matheson, Paul J. Lehner

Cell Host Microbe. 2021 May 12; 29(5): 792–805.e6. doi: 10.1016/j.chom.2021.03.001

PMCID:: PMC8118623

Abstract Article

Select item 52409919.

The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection

Congrong Niu, Christine M. Livingston, Li Li, Rudolf K. Beran, Stephane Daffis, Dhivya Ramakrishnan, Dara Burdette, Leanne Peiser, Eduardo Salas, Hilario Ramos, Mei Yu, Guofeng Cheng, Michel Strubin, William E. Delaney IV, Simon P. Fletcher

PLoS One. 2017; 12(1): e0169648. Published online 2017 Jan 17. doi: 10.1371/journal.pone.0169648

PMCID:: PMC5240991

Abstract Article PDF–3.8M

Select item 513378310.

Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress

Dideke E. Verver, Yi Zheng, Dave Speijer, Ron Hoebe, Henk L. Dekker, Sjoerd Repping, Jan Stap, Geert Hamer

Int J Mol Sci. 2016 Nov; 17(11): 1782. Published online 2016 Oct 26. doi: 10.3390/ijms17111782

PMCID:: PMC5133783

Abstract Article PDF–3.9M

Select item 507899311.

Hepatitis B Virus X protein promotes degradation of SMC5/6 to enhance HBV replication

Christopher M. Murphy, Yanping Xu, Feng Li, Kouki Nio, Natalia Reszka-Blanco, Xiaodong Li, Yaxu Wu, Yanbao Yu, Yue Xiong, Lishan Su

Cell Rep. Author manuscript; available in PMC 2016 Oct 25.

Published in final edited form as: Cell Rep. 2016 Sep 13; 16(11): 2846–2854. doi: 10.1016/j.celrep.2016.08.026

PMCID:: PMC5078993

Abstract Article PDF–2.2M

Select item 34381412.

Coordination of DNA Damage Responses via the Smc5/Smc6 Complex

Susan H. Harvey, Daniel M. Sheedy, Andrew R. Cuddihy, Matthew J. O'Connell

Mol Cell Biol. 2004 Jan; 24(2): 662–674. doi: 10.1128/MCB.24.2.662-674.2004

PMCID:: PMC343814

Abstract Article PDF–834K

Select item 620648413.

PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner

Wei Xu, Chunqiang Ma, Qi Zhang, Rong Zhao, Dan Hu, Xuewu Zhang, Junbo Chen, Fang Liu, Kailang Wu, Yingle Liu, Jianguo Wu

J Virol. 2018 Nov 15; 92(22): e00825-18. Prepublished online 2018 Sep 5. Published online 2018 Oct 29. doi: 10.1128/JVI.00825-18

PMCID:: PMC6206484

Abstract Article PDF–5.1M

Select item 529027714.

Specialized interfaces of Smc5/6 control hinge stability and DNA association

Aaron Alt, Hung Q. Dang, Owen S. Wells, Luis M. Polo, Matt A. Smith, Grant A. McGregor, Thomas Welte, Alan R. Lehmann, Laurence H. Pearl, Johanne M. Murray, Antony W. Oliver

Nat Commun. 2017; 8: 14011. Published online 2017 Jan 30. doi: 10.1038/ncomms14011

PMCID:: PMC5290277

Abstract Article PDF–3.0M

Select item 3732615.

Characterization of a Novel Human SMC Heterodimer Homologous to the Schizosaccharomyces pombe Rad18/Spr18 Complex

Elaine M. Taylor, Jeelan S. Moghraby, Jennifer H. Lees, Bep Smit, Peter B. Moens, Alan R. Lehmann

Mol Biol Cell. 2001 Jun; 12(6): 1583–1594. doi: 10.1091/mbc.12.6.1583

PMCID:: PMC37326

Abstract Article PDF–1.1M

Select item 543061616.

Genome-Wide Analysis in Brazilians Reveals Highly Differentiated Native American Genome Regions

Josyf C. Mychaleckyj, Alexandre Havt, Uma Nayak, Relana Pinkerton, Emily Farber, Patrick Concannon, Aldo A. Lima, Richard L. Guerrant

Mol Biol Evol. 2017 Mar; 34(3): 559–574. Published online 2017 Jan 18. doi: 10.1093/molbev/msw249

PMCID:: PMC5430616

Abstract Article PDF–1.6M

Select item 496631217.

Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease

Saskia N. van der Crabben, Marije P. Hennus, Grant A. McGregor, Deborah I. Ritter, Sandesh C.S. Nagamani, Owen S. Wells, Magdalena Harakalova, Ivan K. Chinn, Aaron Alt, Lucie Vondrova, Ron Hochstenbach, Joris M. van Montfrans, Suzanne W. Terheggen-Lagro, Stef van Lieshout, Markus J. van Roosmalen, Ivo Renkens, Karen Duran, Isaac J. Nijman, Wigard P. Kloosterman, Eric Hennekam, Jordan S. Orange, Peter M. van Hasselt, David A. Wheeler, Jan J. Palecek, Alan R. Lehmann, Antony W. Oliver, Laurence H. Pearl, Sharon E. Plon, Johanne M. Murray, Gijs van Haaften

J Clin Invest. 2016 Aug 1; 126(8): 2881–2892. Published online 2016 Jul 18. doi: 10.1172/JCI82890

PMCID:: PMC4966312

Abstract Article PDF–1.1M

Select item 119024218.

Human MMS21/NSE2 Is a SUMO Ligase Required for DNA Repair

Patrick Ryan Potts, Hongtao Yu

Mol Cell Biol. 2005 Aug; 25(16): 7021–7032. doi: 10.1128/MCB.25.16.7021-7032.2005

PMCID:: PMC1190242

Abstract Article PDF–780K

Select item 255593619.

Nse1 RING-like Domain Supports Functions of the Smc5-Smc6 Holocomplex in Genome Stability

Stephanie Pebernard, J. Jefferson P. Perry, John A. Tainer, Michael N. Boddy

Mol Biol Cell. 2008 Oct; 19(10): 4099–4109. doi: 10.1091/mbc.E08-02-0226

PMCID:: PMC2555936

Abstract Article PDF–1.1M

Select item 53876520.

Composition and Architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) Complex

John Sergeant, Elaine Taylor, Jan Palecek, Maria Fousteri, Emily A. Andrews, Sara Sweeney, Hideo Shinagawa, Felicity Z. Watts, Alan R. Lehmann

Mol Cell Biol. 2005 Jan; 25(1): 172–184. doi: 10.1128/MCB.25.1.172-184.2005

PMCID:: PMC538765

Abstract Article PDF–1.0M

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PMC Links for Gene (Select 79677) (63)
PMC
PREDICTED: Homo sapiens structural maintenance of chromosomes 6 (SMC6), transcri...
PREDICTED: Homo sapiens structural maintenance of chromosomes 6 (SMC6), transcript variant X5, mRNA
gi|2217331048|ref|XM_017004916.3|

Nucleotide
PREDICTED: Homo sapiens ubiquitin C-terminal hydrolase L5 (UCHL5), transcript va...
PREDICTED: Homo sapiens ubiquitin C-terminal hydrolase L5 (UCHL5), transcript variant X13, mRNA
gi|2217268031|ref|XM_047422353.1|

Nucleotide
PREDICTED: Homo sapiens ubiquitin C-terminal hydrolase L5 (UCHL5), transcript va...
PREDICTED: Homo sapiens ubiquitin C-terminal hydrolase L5 (UCHL5), transcript variant X9, mRNA
gi|2462509906|ref|XM_054336948.1|

Nucleotide
electron transfer flavoprotein subunit beta isoform X1 [Homo sapiens]
electron transfer flavoprotein subunit beta isoform X1 [Homo sapiens]
gi|2462563719|ref|XP_054176164.1|

Protein

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