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Select item 86836311.

Novel compound heterozygous STN1 variants are associated with Coats Plus syndrome

Tanvi Acharya, Helen V. Firth, Shilpa Dugar, Tassos Grammatikopoulos, Luis Seabra, Angharad Walters, Yanick J. Crow, Alasdair P. J. Parker

Mol Genet Genomic Med. 2021 Dec; 9(12): e1708. Published online 2021 Jun 10. doi: 10.1002/mgg3.1708

PMCID:: PMC8683631

Abstract Article PDF–906K

Select item 70397112.

Association between common telomere length genetic variants and telomere length in an African population and impacts of HIV and TB

Stephanie Wang, Emily Chang, Patrick Byanyima, Peter Huang, Ingvar Sanyu, Emmanuel Musisi, Abdul Sessolo, J. Lucian Davis, William Worodria, Laurence Huang, Jue Lin, Inflammation, Aging, Microbes and Obstructive Lung Disease (I AM OLD) Study

J Hum Genet. Author manuscript; available in PMC 2020 Feb 24.

Published in final edited form as: J Hum Genet. 2019 Oct; 64(10): 1033–1040. Published online 2019 Aug 6. doi: 10.1038/s10038-019-0646-9

PMCID:: PMC7039711

Abstract Article PDF–470K

Select item 56696203.

Correction

Cell Rep. Author manuscript; available in PMC 2017 Nov 3.

Published in final edited form as: Cell Rep. 2016 Aug 16; 16(7): 2048. doi: 10.1016/j.celrep.2016.08.008

Corrects:: Cell Rep. 2016 Aug 2; 16(5): 1300–1314.

PMCID:: PMC5669620

Correction PDF–27K

Select item 48443564.

Beyond Telomerase: Telomere Instability as a Novel Target for Cancer Therapy

Maria Fadri-Moskwik, Qing Zhou, Weihang Chai

J Mol Genet Med. Author manuscript; available in PMC 2016 Apr 25.

Published in final edited form as: J Mol Genet Med. 2013 Dec; 7(4): 91. Published online 2013 Dec 9. doi: 10.4172/1747-0862.1000091

PMCID:: PMC4844356

Abstract Article PDF–331K

Select item 35157545.

Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in

Chenhui Huang, Xueyu Dai, Weihang Chai

Cell Res. 2012 Dec; 22(12): 1681–1695. Published online 2012 Sep 11. doi: 10.1038/cr.2012.132

PMCID:: PMC3515754

Abstract Article PDF–1.4M

Select item 35136926.

Human CST has independent functions during telomere duplex replication and C-strand fill-in

Feng Wang, Jason A. Stewart, Christopher Kasbek, Yong Zhao, Woodring E. Wright, Carolyn M. Price

Cell Rep. Author manuscript; available in PMC 2012 Dec 4.

Published in final edited form as: Cell Rep. 2012 Nov 29; 2(5): 1096–1103. Published online 2012 Nov 8. doi: 10.1016/j.celrep.2012.10.007

PMCID:: PMC3513692

Abstract Article PDF–1.4M

Select item 60894527.

Overlapping open reading frames strongly reduce human and yeast STN1 gene expression and affect telomere function

Victoria Torrance, David Lydall

PLoS Genet. 2018 Aug; 14(8): e1007523. Published online 2018 Aug 1. doi: 10.1371/journal.pgen.1007523

PMCID:: PMC6089452

Abstract Article PDF–6.2M

Select item 60524798.

CTC1‐STN1 coordinates G‐ and C‐strand synthesis to regulate telomere length

Peili Gu, Shuting Jia, Taylor Takasugi, Eric Smith, Jayakrishnan Nandakumar, Eric Hendrickson, Sandy Chang

Aging Cell. 2018 Aug; 17(4): e12783. Published online 2018 May 17. doi: 10.1111/acel.12783

PMCID:: PMC6052479

Abstract Article PDF–3.1M

Select item 57661589.

STN1–POLA2 interaction provides a basis for primase-pol α stimulation by human STN1

Swapna Ganduri, Neal F. Lue

Nucleic Acids Res. 2017 Sep 19; 45(16): 9455–9466. Published online 2017 Jul 19. doi: 10.1093/nar/gkx621

PMCID:: PMC5766158

Abstract Article PDF–3.4M

Select item 537900610.

Telomere length in the two extremes of abnormal fetal growth and the programming effect of maternal arterial hypertension

Mariana Tellechea, Tomas Fernandéz Gianotti, Jorge Alvariñas, Claudio D. González, Silvia Sookoian, Carlos J. Pirola

Sci Rep. 2015; 5: 7869. Published online 2015 Jan 19. doi: 10.1038/srep07869

PMCID:: PMC5379006

Abstract Article PDF–660K

Select item 498652811.

Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects

Amos J. Simon, Atar Lev, Yong Zhang, Batia Weiss, Anna Rylova, Eran Eyal, Nitzan Kol, Ortal Barel, Keren Cesarkas, Michalle Soudack, Noa Greenberg-Kushnir, Michele Rhodes, David L. Wiest, Ginette Schiby, Iris Barshack, Shulamit Katz, Elon Pras, Hana Poran, Haike Reznik-Wolf, Elena Ribakovsky, Carlos Simon, Wadi Hazou, Yechezkel Sidi, Avishay Lahad, Hagar Katzir, Shira Sagie, Haifa A. Aqeilan, Galina Glousker, Ninette Amariglio, Yehuda Tzfati, Sara Selig, Gideon Rechavi, Raz Somech

J Exp Med. 2016 Jul 25; 213(8): 1429–1440. doi: 10.1084/jem.20151618

PMCID:: PMC4986528

Abstract Article PDF–2.1M

Select item 386144812.

Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart Disease

Cécilia G. Maubaret, Klelia D. Salpea, Casey E. Romanoski, Lasse Folkersen, Jackie A. Cooper, Coralea Stephanou, Ka Wah Li, Jutta Palmen, Anders Hamsten, Andrew Neil, Jeffrey W. Stephens, Aldons J. Lusis, Per Eriksson, Philippa J. Talmud, Steve E. Humphries, the Simon Broome Research Group , the EARSII consortium

PLoS One. 2013; 8(12): e83122. Published online 2013 Dec 12. doi: 10.1371/journal.pone.0083122

PMCID:: PMC3861448

Abstract Article PDF–1015K

Select item 343378013.

Human CST promotes telomere duplex replication and general replication restart after fork stalling

Jason A Stewart, Feng Wang, Mary F Chaiken, Christopher Kasbek, Paul D Chastain, II, Woodring E Wright, Carolyn M Price

EMBO J. 2012 Aug 29; 31(17): 3537–3549. Published online 2012 Aug 3. doi: 10.1038/emboj.2012.215

PMCID:: PMC3433780

Abstract Article PDF–1.7M

Select item 1116094014.

CST–Polymeraseα-primase solves a second telomere end-replication problem

Hiroyuki Takai, Valentina Aria, Pamela Borges, Joseph T. P. Yeeles, Titia de Lange

Nature. Author manuscript; available in PMC 2024 Jun 7.

Published in final edited form as: Nature. 2024 Mar; 627(8004): 664–670. Published online 2024 Feb 28. doi: 10.1038/s41586-024-07137-1

PMCID:: PMC11160940

Abstract Article PDF–2.4M

Select item 1068950315.

CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection

Rishi Kumar Jaiswal, Kai-Hang Lei, Megan Chastain, Yuan Wang, Olga Shiva, Shan Li, Zhongsheng You, Peter Chi, Weihang Chai

Nat Commun. 2023; 14: 7882. Published online 2023 Nov 30. doi: 10.1038/s41467-023-43685-2

PMCID:: PMC10689503

Abstract Article PDF–5.2M

Select item 1026823116.

Structures of the human CST-Polα–primase complex bound to telomere templates

Qixiang He, Xiuhua Lin, Bianca L. Chavez, Sourav Agrawal, Benjamin L. Lusk, Ci Ji Lim

Nature. Author manuscript; available in PMC 2023 Jun 15.

Published in final edited form as: Nature. 2022 Aug; 608(7924): 826–832. Published online 2022 Jul 13. doi: 10.1038/s41586-022-05040-1

PMCID:: PMC10268231

Abstract Article PDF–6.4M

Select item 940243917.

Reconstitution of a telomeric replicon organized by CST

Arthur J. Zaug, Karen J. Goodrich, Jessica J. Song, Ashley E. Sullivan, Thomas R. Cech

Nature. 2022; 608(7924): 819–825. Published online 2022 Jul 13. doi: 10.1038/s41586-022-04930-8

PMCID:: PMC9402439

Abstract Article PDF–29M

Select item 809326618.

Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population

Xuling Chang, Resham L. Gurung, Ling Wang, Aizhen Jin, Zheng Li, Renwei Wang, Kenneth B. Beckman, Jennifer Adams-Haduch, Wee Yang Meah, Kar Seng Sim, Weng Khong Lim, Sonia Davila, Patrick Tan, Jing Xian Teo, Khung Keong Yeo, Yiamunaa M., Sylvia Liu, Su Chi Lim, Jianjun Liu, Rob M. van Dam, Yechiel Friedlander, Woon-Puay Koh, Jian-Min Yuan, Chiea Chuen Khor, Chew-Kiat Heng, Rajkumar Dorajoo

Commun Biol. 2021; 4: 519. Published online 2021 May 3. doi: 10.1038/s42003-021-02056-7

PMCID:: PMC8093266

Abstract Article PDF–1009K

Select item 808102519.

CST in maintaining genome stability: beyond telomeres

Xinxing Lyu, Pau Biak Sang, Weihang Chai

DNA Repair (Amst) Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: DNA Repair (Amst). 2021 Jun; 102: 103104. Published online 2021 Mar 22. doi: 10.1016/j.dnarep.2021.103104

PMCID:: PMC8081025

Abstract Article PDF–903K

Select item 654741720.

Mammalian CST averts replication failure by preventing G-quadruplex accumulation

Miaomiao Zhang, Bing Wang, Tingfang Li, Rui Liu, Yingnan Xiao, Xin Geng, Guang Li, Qiang Liu, Carolyn M Price, Yang Liu, Feng Wang

Nucleic Acids Res. 2019 Jun 4; 47(10): 5243–5259. Published online 2019 Apr 12. doi: 10.1093/nar/gkz264

PMCID:: PMC6547417

Abstract Article PDF–6.9M

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PMC Links for Gene (Select 79991) (59)
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RecName: Full=CST complex subunit STN1; AltName: Full=Oligonucleotide/oligosacch...
RecName: Full=CST complex subunit STN1; AltName: Full=Oligonucleotide/oligosaccharide-binding fold-containing protein 1; AltName: Full=Suppressor of cdc thirteen homolog
gi|62900737|sp|Q9H668.2|STN1_HUMAN

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