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Items: 1 to 20 of 45

1.
DCAF11 supports targeted protein degradation by electrophilic proteolysis-targeting chimeras
Xiaoyu Zhang, Lena M. Luukkonen, Christie L. Eissler, Vincent M. Crowley, Yu Yamashita, Michael A. Schafroth, Shota Kikuchi, David S. Weinstein, Kent T. Symons, Brian E. Nordin, Joe L. Rodriguez, Thomas G. Wucherpfennig, Ludwig Bauer, Melissa M. Dix, Dean Stamos, Todd M. Kinsella, Gabriel M. Simon, Kristen A. Baltgalvis, Benjamin F. Cravatt
J Am Chem Soc. Author manuscript; available in PMC 2022 Apr 7.
Published in final edited form as: J Am Chem Soc. 2021 Apr 7; 143(13): 5141–5149. Published online 2021 Mar 30. doi: 10.1021/jacs.1c00990
PMCID:
PMC8309050
AbstractArticlePDF–1.4M
2.
TFEB activates Nrf2 by repressing its E3 ubiquitin ligase DCAF11 and promoting phosphorylation of p62
Jee-Yun Park, Sunhyo Kim, Hee Young Sohn, Young Ho Koh, Chulman Jo
Sci Rep. 2019; 9: 14354. Published online 2019 Oct 4. doi: 10.1038/s41598-019-50877-8
PMCID:
PMC6778067
AbstractArticlePDF–1.6M
3.
Activation of TNF‐α/NF‐κB axis enhances CRL4BDCAF11 E3 ligase activity and regulates cell cycle progression in human osteosarcoma cells
Caiguo Zhang, Bin Chen, Kaibiao Jiang, Lifeng Lao, Hongxing Shen, Zhi Chen
Mol Oncol. 2018 Apr; 12(4): 476–494. Published online 2018 Feb 20. doi: 10.1002/1878-0261.12176
PMCID:
PMC5891038
AbstractArticlePDF–1.9M
4.
DDB1 and CUL4 associated factor 11 (DCAF11) mediates degradation of Stem-loop binding protein at the end of S phase
Umidahan Djakbarova, William F. Marzluff, M. Murat Köseoğlu
Cell Cycle. 2016; 15(15): 1986–1996. Published online 2016 Jun 2. doi: 10.1080/15384101.2016.1191708
PMCID:
PMC4968976
AbstractArticlePDF–1017K
5.
Structural basis of UV DNA damage recognition by the DDB1-DDB2 complex
Andrea Scrima, Renata Koníčková, Bryan K. Czyzewski, Yusuke Kawasaki, Philip D. Jeffrey, Regina Groisman, Yoshihiro Nakatani, Shigenori Iwai, Nikola P. Pavletich, Nicolas H. Thomä
Cell. Author manuscript; available in PMC 2009 Jun 26.
Published in final edited form as: Cell. 2008 Dec 26; 135(7): 1213–1223. doi: 10.1016/j.cell.2008.10.045
PMCID:
PMC2676164
AbstractArticlePDF–3.3M
6.
WDR23 regulates NRF2 independently of KEAP1
Jacqueline Y. Lo, Brett N. Spatola, Sean P. Curran
PLoS Genet. 2017 Apr; 13(4): e1006762. Published online 2017 Apr 28. doi: 10.1371/journal.pgen.1006762
PMCID:
PMC5428976
AbstractArticlePDF–21M
7.
CRL4BDCAF11 E3 ligase targets p21 for degradation to control cell cycle progression in human osteosarcoma cells
Zhi Chen, Kun Wang, Canglong Hou, Kaibiao Jiang, Bin Chen, Jianwei Chen, Lifeng Lao, Lie Qian, Guibin Zhong, Zude Liu, Caiguo Zhang, Hongxing Shen
Sci Rep. 2017; 7: 1175. Published online 2017 Apr 26. doi: 10.1038/s41598-017-01344-9
PMCID:
PMC5430835
AbstractArticlePDF–2.1M
8.
The WD40 Repeat Protein WDR-23 Functions with the CUL4/DDB1 Ubiquitin Ligase To Regulate Nuclear Abundance and Activity of SKN-1 in Caenorhabditis elegans
Keith P. Choe, Aaron J. Przybysz, Kevin Strange
Mol Cell Biol. 2009 May; 29(10): 2704–2715. Published online 2009 Mar 9. doi: 10.1128/MCB.01811-08
PMCID:
PMC2682033
AbstractArticlePDF–2.2M
9.
Cryptochromes-mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism
Luca Rizzini, Daniel C. Levine, Mark Perelis, Joseph Bass, Clara B. Peek, Michele Pagano
Curr Biol. Author manuscript; available in PMC 2020 Jun 17.
Published in final edited form as: Curr Biol. 2019 Jun 17; 29(12): 1954–1962.e4. Published online 2019 May 30. doi: 10.1016/j.cub.2019.04.073
PMCID:
PMC6581574
AbstractArticlePDF–1.1M
10.
DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4–ROC1 ubiquitin ligases
Yizhou Joseph He, Chad M. McCall, Jian Hu, Yaxue Zeng, Yue Xiong
Genes Dev. 2006 Nov 1; 20(21): 2949–2954. doi: 10.1101/gad.1483206
PMCID:
PMC1620025
AbstractArticlePDF–420K
11.
Vif hijacks CBF – β to degrade APOBEC3G and promote HIV–1 infection
Stefanie Jäger, Dong Young Kim, Judd F. Hultquist, Keisuke Shindo, Rebecca S. LaRue, Eunju Kwon, Ming Li, Brett D. Anderson, Linda Yen, David Stanley, Cathal Mahon, Joshua Kane, Kathy Franks-Skiba, Peter Cimermancic, Alma Burlingame, Andrej Sali, Charles S. Craik, Reuben S. Harris, John D. Gross, Nevan J. Krogan
Nature. Author manuscript; available in PMC 2013 Jan 19.
Published in final edited form as: Nature. 2011 Dec 21; 481(7381): 371–375. Published online 2011 Dec 21. doi: 10.1038/nature10693
PMCID:
PMC3310910
AbstractArticlePDF–928K
12.
CUL4B Promotes Breast Carcinogenesis by Coordinating with Transcriptional Repressor Complexes in Response to Hypoxia Signaling Pathway
Wei Huang, Jingyao Zhang, Miaomiao Huo, Jie Gao, Tianshu Yang, Xin Yin, Pei Wang, Shuai Leng, Dandan Feng, Yang Chen, Yang Yang, Yan Wang
Adv Sci (Weinh) 2021 May; 8(10): 2001515. Published online 2021 Mar 16. doi: 10.1002/advs.202001515
PMCID:
PMC8132058
AbstractArticlePDF–10M
13.
An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases
Michael Hans Olma, Marcia Roy, Thierry Le Bihan, Izabela Sumara, Sarah Maerki, Brett Larsen, Manfredo Quadroni, Matthias Peter, Mike Tyers, Lionel Pintard
J Cell Sci. 2009 Apr 1; 122(7): 1035–1044. Published online 2009 Mar 18. doi: 10.1242/jcs.043539
PMCID:
PMC2720933
AbstractArticle
14.
CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling
Si‐Han Chen, Gwendolyn M Jang, Ruth Hüttenhain, David E Gordon, Dan Du, Billy W Newton, Jeffrey R Johnson, Joseph Hiatt, Judd F Hultquist, Tasha L Johnson, Yi‐Liang Liu, Lily A Burton, Jordan Ye, Kurt M Reichermeier, Robert M Stroud, Alexander Marson, Jayanta Debnath, John D Gross, Nevan J Krogan
EMBO J. 2018 Sep 14; 37(18): e97508. Published online 2018 Aug 30. doi: 10.15252/embj.201797508
PMCID:
PMC6138441
AbstractArticlePDF–1.7M
15.
Identification of proteins that interact with alpha A-crystallin using a human proteome microarray
Qi Fan, Lv-Zhen Huang, Xiang-Jia Zhu, Ke-Ke Zhang, Hong-Fei Ye, Yi Luo, Xing-Huai Sun, Peng Zhou, Yi Lu
Mol Vis. 2014; 20: 117–124. Published online 2014 Jan 14.
PMCID:
PMC3893783
AbstractArticlePDF–1024K
16.
IKK-mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5
Jingzi Zhang, Ruoyu Zhao, Christine L. N. Bryant, Kenneth Wu, Zhihong Liu, Yibing Ding, Yue Zhao, Bin Xue, Zhen-Qiang Pan, Chaojun Li, Lan Huang, Lei Fang
J Proteome Res. Author manuscript; available in PMC 2020 Jun 17.
Published in final edited form as: J Proteome Res. 2020 Mar 6; 19(3): 1119–1130. Published online 2020 Feb 3. doi: 10.1021/acs.jproteome.9b00626
PMCID:
PMC7299130
AbstractArticlePDF–2.2M
17.
Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II
Yujing Li, Yunhua Liu, Hanchen Xu, Guanglong Jiang, Kevin Van der Jeught, Yuanzhang Fang, Zhuolong Zhou, Lu Zhang, Michael Frieden, Lifei Wang, Zhenhua Luo, Milan Radovich, Bryan P. Schneider, Yibin Deng, Yunlong Liu, Kun Huang, Bin He, Jin Wang, Xiaoming He, Xinna Zhang, Guang Ji, Xiongbin Lu
Nat Commun. 2018; 9: 4394. Published online 2018 Oct 22. doi: 10.1038/s41467-018-06811-z
PMCID:
PMC6197287
AbstractArticlePDF–1.9M
18.
Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex
Marissa M. Minor, F. Blaine Hollinger, Adrienne L. McNees, Sung Yun Jung, Antrix Jain, Joseph M. Hyser, Karl-Dimiter Bissig, Betty L. Slagle
Cells. 2020 Apr; 9(4): 834. Published online 2020 Mar 30. doi: 10.3390/cells9040834
PMCID:
PMC7226812
AbstractArticlePDF–2.3M
19.
ARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection
Ruth Hüttenhain, Jiewei Xu, Lily A. Burton, David E. Gordon, Judd F. Hultquist, Jeffrey R. Johnson, Laura Satkamp, Joseph Hiatt, David Y. Rhee, Kheewoong Baek, David C. Crosby, Alan D. Frankel, Alexander Marson, J. Wade Harper, Arno F. Alpi, Brenda A. Schulman, John D. Gross, Nevan J. Krogan
Cell Host Microbe. Author manuscript; available in PMC 2020 Jul 10.
Published in final edited form as: Cell Host Microbe. 2019 Jul 10; 26(1): 86–99.e7. Published online 2019 Jun 25. doi: 10.1016/j.chom.2019.05.008
PMCID:
PMC7153695
AbstractArticlePDF–2.6M
20.
Phospho-tyrosine dependent protein–protein interaction network
Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl
Mol Syst Biol. 2015 Mar; 11(3): 0794. Published online 2015 Mar 26. doi: 10.15252/msb.20145968
PMCID:
PMC4380928
AbstractArticlePDF–1.9M

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