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Select item 50351891.

Novel Calmodulin Mutations Associated with Congenital Long QT Syndrome Affect Calcium Current in Human Cardiomyocytes

Daniel C. Pipilas, Christopher N. Johnson, Gregory Webster, Jurg Schlaepfer, Florence Fellmann, Nicole Sekarski, Lisa M. Wren, Kateryna V. Ogorodnik, Daniel M. Chazin, Walter J. Chazin, Lia Crotti, Zahurul A. Bhuiyan, Alfred L. George, Jr.

Heart Rhythm. Author manuscript; available in PMC 2017 Oct 1.

Published in final edited form as: Heart Rhythm. 2016 Oct; 13(10): 2012–2019. Published online 2016 Jul 1. doi: 10.1016/j.hrthm.2016.06.038

PMCID:: PMC5035189

Abstract Article PDF–1.2M

Select item 48395662.

Calmodulin 2 Mutation N98S Is Associated with Unexplained Cardiac Arrest in Infants Due to Low Clinical Penetrance Electrical Disorders

Juan Jiménez-Jáimez, Julián Palomino Doza, Ángeles Ortega, Rosa Macías-Ruiz, Francesca Perin, M. Mar Rodríguez-Vázquez del Rey, Martín Ortiz-Genga, Lorenzo Monserrat, Roberto Barriales-Villa, Enrique Blanca, Miguel Álvarez, Luis Tercedor

PLoS One. 2016; 11(4): e0153851. Published online 2016 Apr 21. doi: 10.1371/journal.pone.0153851

PMCID:: PMC4839566

Abstract Article PDF–1.2M

Select item 41409983.

Novel Calmodulin (CALM2) Mutations Associated with Congenital Arrhythmia Susceptibility

Naomasa Makita, Nobue Yagihara, Lia Crotti, Christopher N. Johnson, Britt-Maria Beckmann, Michelle S. Roh, Daichi Shigemizu, Peter Lichtner, Taisuke Ishikawa, Takeshi Aiba, Tessa Homfray, Elijah R. Behr, Didier Klug, Isabelle Denjoy, Elisa Mastantuono, Daniel Theisen, Tatsuhiko Tsunoda, Wataru Satake, Tatsushi Toda, Hidewaki Nakagawa, Yukiomi Tsuji, Takeshi Tsuchiya, Hirokazu Yamamoto, Yoshihiro Miyamoto, Naoto Endo, Akinori Kimura, Kouichi Ozaki, Hideki Motomura, Kenji Suda, Toshihiro Tanaka, Peter J. Schwartz, Thomas Meitinger, Stefan Kääb, Pascale Guicheney, Wataru Shimizu, Zahurul A. Bhuiyan, Hiroshi Watanabe, Walter J. Chazin, Alfred L. George, Jr.

Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Aug 1.

Published in final edited form as: Circ Cardiovasc Genet. 2014 Aug; 7(4): 466–474. Published online 2014 Jun 10. doi: 10.1161/CIRCGENETICS.113.000459

PMCID:: PMC4140998

Abstract Article PDF–2.4M

Select item 104359394.

microRNA‐651‐5p affects the proliferation, migration, and invasion of lung cancer cells by regulating Calmodulin 2 expression

Yaoguo Lang, Xianglong Kong, Benkun Liu, Xiangyuan Jin, Lantao Chen, Shidong Xu

Clin Respir J. 2023 Aug; 17(8): 754–763. Published online 2023 Jul 20. doi: 10.1111/crj.13665

PMCID:: PMC10435939

Abstract Article PDF–2.2M

Select item 38347685.

Calmodulin Mutations Associated with Recurrent Cardiac Arrest in Infants

Lia Crotti, Christopher N. Johnson, Elisabeth Graf, Gaetano M. De Ferrari, Bettina F. Cuneo, Marc Ovadia, John Papagiannis, Michael D. Feldkamp, Subodh G. Rathi, Jennifer D. Kunic, Matteo Pedrazzini, Thomas Wieland, Peter Lichtner, Britt-Maria Beckmann, Travis Clark, Christian Shaffer, D. Woodrow Benson, Stefan Kääb, Thomas Meitinger, Tim M. Strom, Walter J. Chazin, Peter J. Schwartz, Alfred L. George, Jr.

Circulation. Author manuscript; available in PMC 2014 Mar 5.

Published in final edited form as: Circulation. 2013 Mar 5; 127(9): 10.1161/CIRCULATIONAHA.112.001216. Published online 2013 Feb 6. doi: 10.1161/CIRCULATIONAHA.112.001216

PMCID:: PMC3834768

Abstract Article PDF–2.9M

Select item 76147656.

Prevalence and Phenotypic Correlations of Calmodulinopathy-Causative CALM1-3 Variants Detected in a Multi-Center Molecular Autopsy Cohort of Sudden Unexplained Death Victims

Daniel J. Clemens, Belinda Gray, Richard D. Bagnall, David J. Tester, John R. Giudicessi, Joseph J. Maleszewski, Lia Crotti, Peter J. Schwartz, Emma Matthews, Christopher Semsarian, Elijah R. Behr, Michael J. Ackerman

Circ Genom Precis Med. Author manuscript; available in PMC 2023 Jul 17.

Published in final edited form as: Circ Genom Precis Med. 2020 Dec 1; 13(6): e003032. Published online 2020 Nov 15. doi: 10.1161/CIRCGEN.120.003032

PMCID:: PMC7614765

Article PDF–744K

Select item 32952677.

Crystallographic basis for calcium regulation of sodium channels

Maen F. Sarhan, Ching-Chieh Tung, Filip Van Petegem, Christopher A. Ahern

Proc Natl Acad Sci U S A. 2012 Feb 28; 109(9): 3558–3563. Published online 2012 Feb 13. doi: 10.1073/pnas.1114748109

PMCID:: PMC3295267

Abstract Article PDF–1.3M

Select item 27263678.

Potent neutralization of anthrax edema toxin by a humanized monoclonal antibody that competes with calmodulin for edema factor binding

Zhaochun Chen, Mahtab Moayeri, Huaying Zhao, Devorah Crown, Stephen H. Leppla, Robert H. Purcell

Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32): 13487–13492. Published online 2009 Jul 27. doi: 10.1073/pnas.0906581106

PMCID:: PMC2726367

Abstract Article PDF–1.0M

Select item 26050169.

Non-canonical binding of calmodulin to aquaporin-0: implications for channel regulation

Steve L. Reichow, Tamir Gonen

Structure. Author manuscript; available in PMC 2009 Sep 10.

Published in final edited form as: Structure. 2008 Sep 10; 16(9): 1389–1398. doi: 10.1016/j.str.2008.06.011

PMCID:: PMC2605016

Abstract Article PDF–2.3M

Select item 55412410.

Calcium-independent calmodulin binding and two-metal–ion catalytic mechanism of anthrax edema factor

Yuequan Shen, Natalia L Zhukovskaya, Qing Guo, Jan Florián, Wei-Jen Tang

EMBO J. 2005 Mar 9; 24(5): 929–941. Published online 2005 Feb 17. doi: 10.1038/sj.emboj.7600574

PMCID:: PMC554124

Abstract Article PDF–653K

Select item 36577411.

Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection

Yuequan Shen, Natalia L. Zhukovskaya, Michael I. Zimmer, Sandriyana Soelaiman, Pamela Bergson, Chyung-Ru Wang, Craig S. Gibbs, Wei-Jen Tang

Proc Natl Acad Sci U S A. 2004 Mar 2; 101(9): 3242–3247. Published online 2004 Feb 20. doi: 10.1073/pnas.0306552101

PMCID:: PMC365774

Abstract Article PDF–537K

Select item 624125112.

Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures

Chia-Hsueh Lee, Roderick MacKinnon

Science. Author manuscript; available in PMC 2018 Nov 19.

Published in final edited form as: Science. 2018 May 4; 360(6388): 508–513. doi: 10.1126/science.aas9466

PMCID:: PMC6241251

Abstract Article PDF–1006K

Select item 376645013.

Allosteric mechanism of water channel gating by Ca²⁺–calmodulin

Steve L. Reichow, Daniel M. Clemens, J. Alfredo Freites, Karin L. Németh-Cahalan, Matthias Heyden, Douglas J. Tobias, James E. Hall, Tamir Gonen

Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Nat Struct Mol Biol. 2013 Sep; 20(9): 1085–1092. Published online 2013 Jul 28. doi: 10.1038/nsmb.2630

PMCID:: PMC3766450

Abstract Article PDF–2.5M

Select item 361054014.

Crystal structure of the ternary complex of a NaV C-terminal domain, a fibroblast growth factor homologous factor, and calmodulin

Chaojian Wang, Ben C. Chung, Haidun Yan, Seok-Yong Lee, Geoffrey S. Pitt

Structure. Author manuscript; available in PMC 2013 Jul 3.

Published in final edited form as: Structure. 2012 Jul 3; 20(7): 1167–1176. Published online 2012 Jun 14. doi: 10.1016/j.str.2012.05.001

PMCID:: PMC3610540

Abstract Article PDF–2.0M

Select item 302090115.

Insights into voltage-gated calcium channel regulation from the structure of the Ca_V1.2 IQ domain–Ca²⁺/calmodulin complex

Filip Van Petegem, Franck C Chatelain, Daniel L Minor, Jr

Nat Struct Mol Biol. Author manuscript; available in PMC 2011 Jan 13.

Published in final edited form as: Nat Struct Mol Biol. 2005 Dec; 12(12): 1108–1115. Published online 2005 Nov 20. doi: 10.1038/nsmb1027

PMCID:: PMC3020901

Abstract Article PDF–865K

Select item 302064816.

Multiple C-terminal tail Ca²⁺/CaMs regulate Ca_V1.2 function but do not mediate channel dimerization

Eun Young Kim, Christine H Rumpf, Filip Van Petegem, Ryan J Arant, Felix Findeisen, Elizabeth S Cooley, Ehud Y Isacoff, Daniel L Minor, Jr

EMBO J. 2010 Dec 1; 29(23): 3924–3938. Published online 2010 Oct 15. doi: 10.1038/emboj.2010.260

Correction in:: EMBO J. 2010 Dec 1; 29(23): 4062.

PMCID:: PMC3020648

Abstract Article PDF–2.2M

Select item 300991817.

Binding of Calmodulin to the HIV-1 Matrix Protein Triggers Myristate Exposure

Ruba H. Ghanam, Timothy F. Fernandez, Emily L. Fledderman, Jamil S. Saad

J Biol Chem. 2010 Dec 31; 285(53): 41911–41920. Published online 2010 Oct 18. doi: 10.1074/jbc.M110.179093

PMCID:: PMC3009918

Abstract Article PDF–1.5M

Select item 270123618.

Structures of Ca_V2 Ca²⁺/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation

Eun Young Kim, Christine H. Rumpf, Yuichiro Fujiwara, Elizabeth S. Cooley, Filip Van Petegem, Daniel L. Minor, Jr.

Structure. Author manuscript; available in PMC 2009 Oct 8.

Published in final edited form as: Structure. 2008 Oct 8; 16(10): 1455–1467. doi: 10.1016/j.str.2008.07.010

PMCID:: PMC2701236

Abstract Article PDF–4.2M

Select item 265439119.

Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca²⁺·calmodulins

Jennifer L. Fallon, Mariah R. Baker, Liangwen Xiong, Ryan E. Loy, Guojun Yang, Robert T. Dirksen, Susan L. Hamilton, Florante A. Quiocho

Proc Natl Acad Sci U S A. 2009 Mar 31; 106(13): 5135–5140. Published online 2009 Mar 11. doi: 10.1073/pnas.0807487106

PMCID:: PMC2654391

Abstract Article PDF–849K

Select item 237346020.

Nef of HIV-1 interacts directly with calcium-bound calmodulin

Nobuhiro Hayashi, Mamoru Matsubara, Yuji Jinbo, Koiti Titani, Yoshinobu Izumi, Norio Matsushima

Protein Sci. 2002 Mar; 11(3): 529–537. doi: 10.1110/ps.23702

PMCID:: PMC2373460

Abstract Article PDF–230K

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