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Select item 102384161.

A pan-cancer analysis of the role of USP5 in human cancers

Bokang Yan, Jiaxing Guo, Shuang Deng, Dongliang Chen, Meiyuan Huang

Sci Rep. 2023; 13: 8972. Published online 2023 Jun 2. doi: 10.1038/s41598-023-35793-2

PMCID:: PMC10238416

Abstract Article PDF–15M

Select item 83910722.

Two ZnF-UBP domains in isopeptidase T (USP5)

George V. Avvakumov, John R. Walker, Sheng Xue, Abdellah Allali-Hassani, Abdalin Asinas, Usha B. Nair, Xianyang Fang, Xiaobing Zuo, Yun-Xing Wang, Keith D. Wilkinson, Sirano Dhe-Paganon

Biochemistry. Author manuscript; available in PMC 2021 Aug 27.

Published in final edited form as: Biochemistry. 2012 Feb 14; 51(6): 1188–1198. Published online 2012 Feb 3. doi: 10.1021/bi200854q

PMCID:: PMC8391072

Abstract Article PDF–2.0M

Select item 107875063.

PFKP deubiquitination and stabilization by USP5 activate aerobic glycolysis to promote triple-negative breast cancer progression

Zi-Mei Peng, Xiao-Jian Han, Tao Wang, Jian-Jun Li, Chun-Xi Yang, Fang-Fang Tou, Zhen Zhang

Breast Cancer Res. 2024; 26: 10. Published online 2024 Jan 12. doi: 10.1186/s13058-024-01767-z

PMCID:: PMC10787506

Abstract Article PDF–11M

Select item 105530064.

USP5 promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein

Songchang Shi, Xiaobin Pan, Minyong Chen, Lihui Zhang, Shujuan Zhang, Xincai Wang, Songjing Shi, Zhixin Chen, Wei Lin, Yi Jiang

Hepatol Commun. 2023 Aug; 7(8): e0193. Published online 2023 Aug 3. doi: 10.1097/HC9.0000000000000193

PMCID:: PMC10553006

Abstract Article PDF–1.7M

Select item 85779675.

Deubiquitinase USP5 promotes non-small cell lung cancer cell proliferation by stabilizing cyclin D1

Zhiwei Zhang, Zihan Cui, Zhuolin Xie, Chang Li, Chun Xu, Xia Guo, Jie Yu, Tengfei Chen, Francesco Facchinetti, Hanibal Bohnenberger, Tracy L. Leong, Yufeng Xie, Xinliang Mao, Jun Zhao

Transl Lung Cancer Res. 2021 Oct; 10(10): 3995–4011. doi: 10.21037/tlcr-21-767

PMCID:: PMC8577967

Abstract Article PDF–4.6M

Select item 85713066.

USP5 facilitates non-small cell lung cancer progression through stabilization of PD-L1

Jinghua Pan, Yiting Qiao, Congcong Chen, Hongjing Zang, Xiaojing Zhang, Feng Qi, Cunjie Chang, Fan Yang, Mengqing Sun, Shengbin Lin, Quandong Tang, Lina Li, Menglan Wang, Minjie Wu, Yongzhu Liu, Caiyong Lai, Jianxiang Chen, Guo Chen

Cell Death Dis. 2021 Nov; 12(11): 1051. Published online 2021 Nov 5. doi: 10.1038/s41419-021-04356-6

PMCID:: PMC8571306

Abstract Article PDF–3.3M

Select item 84153577.

USP5 Sustains the Proliferation of Glioblastoma Through Stabilization of CyclinD1

Gen Li, Tianquan Yang, Yanling Chen, Jianping Bao, Di Wu, Xiaohan Hu, Chenxi Feng, Lixiao Xu, Mei Li, Gang Li, Meifang Jin, Yunyun Xu, Rui Zhang, Guanghui Qian, Jian Pan

Front Pharmacol. 2021; 12: 720307. Published online 2021 Aug 16. doi: 10.3389/fphar.2021.720307

PMCID:: PMC8415357

Abstract Article PDF–2.8M

Select item 77440278.

MAFG‐AS1 promotes tumor progression via regulation of the HuR/PTBP1 axis in bladder urothelial carcinoma

Mengqing Xiao, Jianye Liu, Liang Xiang, Kai Zhao, Dong He, Qinghai Zeng, Qun Zhang, Dan Xie, Minhua Deng, Yuxing Zhu, Yeyu Zhang, Yan Liu, Hao Bo, Xiaoming Liu, Xingyu Chen, Lian Gong, Ying Bao, Yi Hu, Yaxin Cheng, Liping Deng, Rongrong Zhu, Xiaowei Xing, Ming Zhou, Wei Xiong, Yanhong Zhou, Jianda Zhou, Xiaohui Li, Ke Cao

Clin Transl Med. 2020 Dec; 10(8): e241. Published online 2020 Dec 16. doi: 10.1002/ctm2.241

PMCID:: PMC7744027

Abstract Article PDF–17M

Select item 77266689.

Depleting deubiquitinating enzymes promotes apoptosis in glioma cell line via RNA binding proteins SF2/ASF1

Vidhi Vashistha, Sachin Bhardwaj, Birendra K. Yadav, Ajay K. Yadav

Biochem Biophys Rep. 2020 Dec; 24: 100846. Published online 2020 Dec 8. doi: 10.1016/j.bbrep.2020.100846

PMCID:: PMC7726668

Abstract Article PDF–5.3M

Select item 756706110.

Mesenchymal stem cells reverse EMT process through blocking the activation of NF-κB and Hedgehog pathways in LPS-induced acute lung injury

Kun Xiao, Wanxue He, Wei Guan, Fei Hou, Peng Yan, Jianqiao Xu, Ting Zhou, Yuhong Liu, Lixin Xie

Cell Death Dis. 2020 Oct; 11(10): 863. Published online 2020 Oct 15. doi: 10.1038/s41419-020-03034-3

PMCID:: PMC7567061

Abstract Article PDF–3.3M

Select item 746857811.

Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis

Xue-han Chen, Yu-jia Xu, Xiao-ge Wang, Peng Lin, Bi-yin Cao, Yuan-ying Zeng, Qi Wang, Zu-bin Zhang, Xin-liang Mao, Tie Zhang

Acta Pharmacol Sin. 2019 Dec; 40(12): 1568–1577. Published online 2019 Jun 13. doi: 10.1038/s41401-019-0249-1

PMCID:: PMC7468578

Abstract Article PDF–2.4M

Select item 708537212.

Proinflammatory Effects of Ubiquitin-Specific Protease 5 (USP5) in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

Xiao-Bo Luo, Jian-Cheng Xi, Zhen Liu, Yu Long, Li-tao Li, Zhan-Peng Luo, Dao-Hong Liu

Mediators Inflamm. 2020; 2020: 8295149. Published online 2020 Mar 9. doi: 10.1155/2020/8295149

PMCID:: PMC7085372

Abstract Article PDF–1.1M

Select item 687444713.

Ubiquitin specific peptidase 5 promotes ovarian cancer cell proliferation through deubiquitinating HDAC2

Yanhua Du, Jun Lin, Rulin Zhang, Wanli Yang, Heng Quan, Lijuan Zang, Yaqin Han, Bing Li, Hong Sun, Jun Wu

Aging (Albany NY) 2019 Nov 15; 11(21): 9778–9793. Published online 2019 Nov 13. doi: 10.18632/aging.102425

PMCID:: PMC6874447

Abstract Article PDF–6.0M

Select item 678888214.

Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

Lina Odqvist, Zala Jevnikar, Rebecca Riise, Lisa Öberg, Magdalena Rhedin, Dag Leonard, Linda Yrlid, Sonya Jackson, Johan Mattsson, Sambit Nanda, Philip Cohen, Axel Knebel, Simon Arthur, Kristofer Thörn, Elisabet Svenungsson, Andreas Jönsen, Iva Gunnarsson, Karolina Tandre, Andrei Alexsson, Alf Kastbom, Solbritt Rantapää-Dahlqvist, Maija-Leena Eloranta, Ann-Christine Syvänen, Anders Bengtsson, Patrik Johansson, Johanna K Sandling, Christopher Sjöwall, Lars Rönnblom, Barry Collins, Outi Vaarala

Ann Rheum Dis. 2019 Oct; 78(10): 1363–1370. Published online 2019 Jul 12. doi: 10.1136/annrheumdis-2019-215434

PMCID:: PMC6788882

Abstract Article PDF–2.0M

Select item 667578715.

circHECTD1 facilitates glutaminolysis to promote gastric cancer progression by targeting miR-1256 and activating β-catenin/c-Myc signaling

Juan Cai, Zhiqiang Chen, Jinguo Wang, Junfeng Wang, Xianjun Chen, Linhu Liang, Min Huang, Zhengrong Zhang, Xueliang Zuo

Cell Death Dis. 2019 Aug; 10(8): 576. Published online 2019 Aug 2. doi: 10.1038/s41419-019-1814-8

PMCID:: PMC6675787

Abstract Article PDF–7.2M

Select item 637617816.

USP5 promotes epithelial-mesenchymal transition by stabilizing SLUG in hepatocellular carcinoma

Jing Meng, Xiaoyu Ai, Yueyang Lei, Weilong Zhong, Baoxin Qian, Kailiang Qiao, Xiaorui Wang, Bijiao Zhou, Hongzhi Wang, Longcong Huai, Xiaoyun Zhang, Jingxia Han, Yinyin Xue, Yuan Liang, Honggang Zhou, Shuang Chen, Tao Sun, Cheng Yang

Theranostics. 2019; 9(2): 573–587. Published online 2019 Jan 1. doi: 10.7150/thno.27654